scholarly journals Development of Rapid and High-Precision Colorimetric Device for Organophosphorus Pesticide Detection Based on Microfluidic Mixer Chip

Micromachines ◽  
2021 ◽  
Vol 12 (3) ◽  
pp. 290
Author(s):  
Jiaqing Xie ◽  
Haoran Pang ◽  
Ruqian Sun ◽  
Tao Wang ◽  
Xiaoyu Meng ◽  
...  
Keyword(s):  
High Precision ◽  
Pesticide Residues ◽  
Rapid Detection ◽  
Large Scale ◽  
Organophosphorus Pesticide ◽  
Dynamics Simulation ◽  
Mixing Efficiency ◽  
Induced Voltage ◽  
Detection Scheme ◽  
Microfluidic Mixer

The excessive pesticide residues in cereals, fruit and vegetables is a big threat to human health, and it is necessary to develop a portable, low-cost and high-precision pesticide residue detection scheme to replace the large-scale laboratory testing equipment for rapid detection of pesticide residues. In this study, a colorimetric device for rapid detection of organophosphorus pesticide residues with high precision based on a microfluidic mixer chip was proposed. The microchannel structure with high mixing efficiency was determined by fluid dynamics simulation, while the corresponding microfluidic mixer chip was designed. The microfluidic mixer chip was prepared by a self-developed liquid crystal display (LCD) mask photo-curing machine. The influence of printing parameters on the accuracy of the prepared chip was investigated. The light source with the optimal wavelength of the device was determined by absorption spectrum measurement, and the relationship between the liquid reservoir depth and detection limit was studied by experiments. The correspondence between pesticide concentration and induced voltage was derived. The minimum detection concentration of the device could reach 0.045 mg·L−1 and the average detection time was reduced to 60 s. The results provide a theoretical and experimental basis for portable and high-precision detection of pesticide residues.

3D-Printed Pneumatic Microfluidic Mixer for Colorimetric Detection of Listeria monocytogenes

2019 ◽  
Vol 62 (3) ◽  
pp. 841-850 ◽  
Author(s):  
Ping Yao ◽  
Ronghui Wang ◽  
Xinge Xi ◽  
Yanbin Li ◽  
Steve Tung
Keyword(s):  
Listeria Monocytogenes ◽  
3D Printing ◽  
Rapid Detection ◽  
Low Cost ◽  
Colorimetric Detection ◽  
Single Step ◽  
Mixing Efficiency ◽  
Enzyme Linked Immunosorbent Assay ◽  
Microfluidic Mixer ◽  
3D Printed

Abstract. 3D printing can significantly improve the current fabrication techniques for microfluidic devices due to its ability to create truly 3D structures in a single step. In this study, an active pneumatic microfluidic mixer was designed and fabricated using an extrusion-based 3D printer and used for rapid detection of . The printed material of the mixer is flexible, semi-transparent, and inexpensive. The fabrication time is significantly shorter than the traditional micromolding process. The printed mixer consists of two pneumatic air chambers and one mixing chamber designed for a fluidic sample size of 100 µL. The length, width, and height of the mixer chip are 13, 12.7, and 9 mm, respectively. The performance of the mixer was tested for different actuation frequencies and pneumatic pressures. The completed 3D-printed mixer was successfully applied to the colorimetric detection of for a concentration range from 102 to 108 cfu mL-1 using an enzyme-linked immunosorbent assay. The experimental results showed that the microfluidic mixer could enhance the mixing efficiency of the fluidic sample through pneumatically actuated diaphragms. In addition, the mixer could accelerate the color development caused by target , and the observed color changes could be discriminated within 5 min by naked eye. The present work will contribute to the development and optimization of a prototype for rapid detection of in food samples. It provides an effective technical approach to realize the fabrication of low-cost microfluidic chips for efficient reagent mixing in microscale biochemical detection systems. Keywords: 3D printing, Listeria monocytogenes, Microfluidic mixer, Rapid detection.

Model-based Control Techniques for Large-Scale High-Precision Stage

2020 ◽  
Vol 140 (4) ◽  
pp. 272-280
Author(s):  
Wataru Ohnishi ◽  
Hiroshi Fujimoto ◽  
Koichi Sakata
Keyword(s):  
High Precision ◽  
Large Scale ◽  
Model Based Control ◽  
Precision Stage ◽  
Control Techniques ◽  
Model Based

Combustion Driven by Fragment-based Ab Initio Molecular Dynamics Simulation

2019 ◽  
Author(s):  
Liqun Cao ◽  
Jinzhe Zeng ◽  
Mingyuan Xu ◽  
Chih-Hao Chin ◽  
Tong Zhu ◽  
...  
Keyword(s):  
Molecular Dynamics ◽  
Ab Initio ◽  
Large Scale ◽  
Methane Combustion ◽  
Combustion Method ◽  
Dynamics Simulation ◽  
Ab Initio Molecular Dynamics ◽  
Computational Time ◽  
Combustion Mechanism ◽  
Daily Lives

Combustion is a kind of important reaction that affects people's daily lives and the development of aerospace. Exploring the reaction mechanism contributes to the understanding of combustion and the more efficient use of fuels. Ab initio quantum mechanical (QM) calculation is precise but limited by its computational time for large-scale systems. In order to carry out reactive molecular dynamics (MD) simulation for combustion accurately and quickly, we develop the MFCC-combustion method in this study, which calculates the interaction between atoms using QM method at the level of MN15/6-31G(d). Each molecule in systems is treated as a fragment, and when the distance between any two atoms in different molecules is greater than 3.5 Å, a new fragment involved two molecules is produced in order to consider the two-body interaction. The deviations of MFCC-combustion from full system calculations are within a few kcal/mol, and the result clearly shows that the calculated energies of the different systems using MFCC-combustion are close to converging after the distance thresholds are larger than 3.5 Å for the two-body QM interactions. The methane combustion was studied with the MFCC-combustion method to explore the combustion mechanism of the methane-oxygen system.

Fast operation of large-scale high-precision matrix based on GPU

2009 ◽  
Vol 29 (4) ◽  
pp. 1177-1179 ◽  
Author(s):  
Chang SU ◽  
Zhong-liang FU ◽  
Yu-chen TAN
Keyword(s):  
High Precision ◽  
Large Scale ◽  
Precision Matrix

scholarly journals A High-Precision Registration Technology Based on Bundle Adjustment in Structured Light Scanning System

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Jianying Yuan ◽  
Qiong Wang ◽  
Xiaoliang Jiang ◽  
Bailin Li
Keyword(s):  
High Precision ◽  
Large Scale ◽  
Structured Light ◽  
Bundle Adjustment ◽  
Scanning System ◽  
Control Points ◽  
Registration Method ◽  
Global Control ◽  
3D Data ◽  
Structured Light Scanning

The multiview 3D data registration precision will decrease with the increasing number of registrations when measuring a large scale object using structured light scanning. In this paper, we propose a high-precision registration method based on multiple view geometry theory in order to solve this problem. First, a multiview network is constructed during the scanning process. The bundle adjustment method from digital close range photogrammetry is used to optimize the multiview network to obtain high-precision global control points. After that, the 3D data under each local coordinate of each scan are registered with the global control points. The method overcomes the error accumulation in the traditional registration process and reduces the time consumption of the following 3D data global optimization. The multiview 3D scan registration precision and efficiency are increased. Experiments verify the effectiveness of the proposed algorithm.

Cohesive Zone Model for the Interface of Multiwalled Carbon Nanotubes and Copper: Molecular Dynamics Simulation

2014 ◽  
Vol 5 (3) ◽  
Author(s):  
Ibrahim Awad ◽  
Leila Ladani
Keyword(s):  
Carbon Nanotubes ◽  
Normal Stress ◽  
Multiwalled Carbon Nanotubes ◽  
Cohesive Zone ◽  
Large Scale ◽  
Cohesive Zone Model ◽  
Dynamics Simulation ◽  
Zone Model ◽  
Multiwalled Carbon ◽  
Significant Difference

Due to their superior mechanical and electrical properties, multiwalled carbon nanotubes (MWCNTs) have the potential to be used in many nano-/micro-electronic applications, e.g., through silicon vias (TSVs), interconnects, transistors, etc. In particular, use of MWCNT bundles inside annular cylinders of copper (Cu) as TSV is proposed in this study. However, the significant difference in scale makes it difficult to evaluate the interfacial mechanical integrity. Cohesive zone models (CZM) are typically used at large scale to determine the mechanical adherence at the interface. However, at molecular level, no routine technique is available. Molecular dynamic (MD) simulations is used to determine the stresses that are required to separate MWCNTs from a copper slab and generate normal stress–displacement curves for CZM. Only van der Waals (vdW) interaction is considered for MWCNT/Cu interface. A displacement controlled loading was applied in a direction perpendicular to MWCNT's axis in different cases with different number of walls and at different temperatures and CZM is obtained for each case. Furthermore, their effect on the CZM key parameters (normal cohesive strength (σmax) and the corresponding displacement (δn) has been studied. By increasing the number of the walls of the MWCNT, σmax was found to nonlinearly decrease. Displacement at maximum stress, δn, showed a nonlinear decrease as well with increasing the number of walls. Temperature effect on the stress–displacement curves was studied. When temperature was increased beyond 1 K, no relationship was found between the maximum normal stress and temperature. Likewise, the displacement at maximum load did not show any dependency to temperature.

Flow Geometry Effects on the Turbulent Mixing Efficiency

2006 ◽  
Vol 128 (4) ◽  
pp. 874-879 ◽  
Author(s):  
Roberto C. Aguirre ◽  
Jennifer C. Nathman ◽  
Haris C. Catrakis
Keyword(s):  
Shear Layer ◽  
Turbulent Mixing ◽  
Large Scale ◽  
Mixture Fraction ◽  
Mixing Efficiency ◽  
Developed Turbulence ◽  
Planar Shear ◽  
Flow Geometry ◽  
Schmidt Numbers ◽  
Geometry Effects

Flow geometry effects are examined on the turbulent mixing efficiency quantified as the mixture fraction. Two different flow geometries are compared at similar Reynolds numbers, Schmidt numbers, and growth rates, with fully developed turbulence conditions. The two geometries are the round jet and the single-stream planar shear layer. At the flow conditions examined, the jet exhibits an ensemble-averaged mixing efficiency which is approximately double the value for the shear layer. This substantial difference is explained fluid mechanically in terms of the distinct large-scale entrainment and mixing-initiation environments and is therefore directly due to flow geometry effects.

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