scholarly journals Understanding Interdependencies between Mechanical Velocity and Electrical Voltage in Electromagnetic Micromixers

Micromachines ◽  
2020 ◽  
Vol 11 (7) ◽  
pp. 636 ◽  
Author(s):  
Noori Kim ◽  
Wei Xuan Chan ◽  
Sum Huan Ng ◽  
Yong-Jin Yoon ◽  
Jont B. Allen
Keyword(s):  
Fluorescent Dyes ◽  
Mixing Time ◽  
Electrical Measurement ◽  
Micro Electro Mechanical Systems ◽  
Mixing Performance ◽  
Micro Total Analysis Systems ◽  
Mechanical Behaviours ◽  
Total Analysis ◽  
Critical Components ◽  
Insight Into

Micromixers are critical components in the lab-on-a-chip or micro total analysis systems technology found in micro-electro-mechanical systems. In general, the mixing performance of the micromixers is determined by characterising the mixing time of a system, for example the time or number of circulations and vibrations guided by tracers (i.e., fluorescent dyes). Our previous study showed that the mixing performance could be detected solely from the electrical measurement. In this paper, we employ electromagnetic micromixers to investigate the correlation between electrical and mechanical behaviours in the mixer system. This work contemplates the “anti-reciprocity” concept by providing a theoretical insight into the measurement of the mixer system; the work explains the data interdependence between the electrical point impedance (voltage per unit current) and the mechanical velocity. This study puts the electromagnetic micromixer theory on a firm theoretical and empirical basis.

Development of a Electro-Osmotic Micromixer for Uniform and Rapid Mixing

2012 ◽  
Author(s):  
Yogendra M. Panta ◽  
Param C. Adhikari ◽  
Sanket Aryal
Keyword(s):  
Chemical Species ◽  
Average Concentration ◽  
Geometrical Parameters ◽  
Mixing Zone ◽  
Original Design ◽  
Mixing Performance ◽  
Micro Total Analysis Systems ◽  
Total Analysis ◽  
Geometric Variables ◽  
Over Time

Micro Total Analysis Systems (μTAS) require rapid yet homogeneous mixing of a number of fluid streams that carry bio/chemical species in the solution. Current analysis has been continued from our previously published work [1]. New models were designed by rendering some particular fluid and geometric variables from the original design and then analyzed for the degree of mixing effectiveness. A careful placement of obstacles in the mixing zone of the model and the electrodes in it showed enhancement in mixing performance. In addition, models with varied geometrical parameters such as converging inlet and diverging outlet yielded even better mixing capabilities. Concentration variances over time at the outlet were simultaneously compared in all models for mixing. Also average concentration was tracked over time so as to confirm the uniformity in mixing. The concentration variances at the outlet have been dramatically observed to be reduced by a factor of at least 10 from our designs as reported earlier [1].

scholarly journals Effect of Aspect Ratio on the Mixing Performance in the Kenics Static Mixer

Processes ◽  
2021 ◽  
Vol 9 (3) ◽  
pp. 464
Author(s):  
Xingren Jiang ◽  
Ning Yang ◽  
Rijie Wang
Keyword(s):  
Pharmaceutical Industry ◽  
Aspect Ratio ◽  
Flow Reactor ◽  
Mixing Time ◽  
Continuous Process ◽  
Scale Up ◽  
Influence Factors ◽  
Continuous Manufacturing ◽  
Static Mixer ◽  
Mixing Performance

Continuous manufacturing has received increasing interest because of the advantages of intrinsic safety and enhanced mass transfer in the pharmaceutical industry. However, the difficulty for scale-up has limited the application of continuous manufacturing for a long time. Recently, the tubular flow reactor equipped with the Kenics static mixer appears to be a solution for the continuous process scale-up. Although many influence factors on the mixing performance in the Kenics static mixer have been investigated, little research has been carried out on the aspect ratio. In this study, we used the coefficient of variation as the mixing evaluation index to investigate the effect of the aspect ratio (0.2–2) on the Kenics static mixer’s mixing performance. The results indicate that a low aspect ratio helps obtain a shorter mixing time and mixer length. This study suggests that adjusting the aspect ratio of the Kenics static mixer can be a new strategy for the scale-up of a continuous process in the pharmaceutical industry.

scholarly journals Glass based Micro Total Analysis Systems: Materials, Fabrication methods, and Applications

2021 ◽  
pp. 129859
Author(s):  
Tao Tang ◽  
Yapeng Yuan ◽  
Yaxiaer Yalikun ◽  
Yochiroh Hosokawa ◽  
Ming Li ◽  
...  
Keyword(s):  
Micro Total Analysis Systems ◽  
Total Analysis
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