scholarly journals Micromirror-Embedded Coverslip Assembly for Bidirectional Microscopic Imaging

Micromachines ◽  
2020 ◽  
Vol 11 (6) ◽  
pp. 582 ◽  
Author(s):  
Dongwoo Lee ◽  
Jihye Kim ◽  
Eunjoo Song ◽  
Ji-Young Jeong ◽  
Eun-chae Jeon ◽  
...  
Keyword(s):  
Cell Biology ◽  
3D Imaging ◽  
Fluorescent Microscopy ◽  
Imaging Systems ◽  
Bright Field ◽  
Imaging Tool ◽  
Reflection Angle ◽  
3D Information ◽  
Disposable Device ◽  
High Reflectance

3D imaging of a biological sample provides information about cellular and subcellular structures that are important in cell biology and related diseases. However, most 3D imaging systems, such as confocal and tomographic microscopy systems, are complex and expensive. Here, we developed a quasi-3D imaging tool that is compatible with most conventional microscopes by integrating micromirrors and microchannel structures on coverslips to provide bidirectional imaging. Microfabricated micromirrors had a precisely 45° reflection angle and optically clean reflective surfaces with high reflectance over 95%. The micromirrors were embedded on coverslips that could be assembled as a microchannel structure. We demonstrated that this simple disposable device allows a conventional microscope to perform bidirectional imaging with simple control of a focal plane. Images of microbeads and cells under bright-field and fluorescent microscopy show that the device can provide a quick analysis of 3D information, such as 3D positions and subcellular structures.

Analyzing the Impact of X-Ray Tomography on the Reliability of Integrated Circuits

2015 ◽  
Author(s):  
Halit Dogan ◽  
Md Mahbub Alam ◽  
Navid Asadizanjani ◽  
Sina Shahbazmohamadi ◽  
Domenic Forte ◽  
...  
Keyword(s):  
Integrated Circuits ◽  
Integrated Circuit ◽  
3D Imaging ◽  
Three Dimensional ◽  
Serial Sectioning ◽  
Promising Technique ◽  
Flash Memories ◽  
X Ray ◽  
3D Information ◽  
The Impact

Abstract X-ray tomography is a promising technique that can provide micron level, internal structure, and three dimensional (3D) information of an integrated circuit (IC) component without the need for serial sectioning or decapsulation. This is especially useful for counterfeit IC detection as demonstrated by recent work. Although the components remain physically intact during tomography, the effect of radiation on the electrical functionality is not yet fully investigated. In this paper we analyze the impact of X-ray tomography on the reliability of ICs with different fabrication technologies. We perform a 3D imaging using an advanced X-ray machine on Intel flash memories, Macronix flash memories, Xilinx Spartan 3 and Spartan 6 FPGAs. Electrical functionalities are then tested in a systematic procedure after each round of tomography to estimate the impact of X-ray on Flash erase time, read margin, and program operation, and the frequencies of ring oscillators in the FPGAs. A major finding is that erase times for flash memories of older technology are significantly degraded when exposed to tomography, eventually resulting in failure. However, the flash and Xilinx FPGAs of newer technologies seem less sensitive to tomography, as only minor degradations are observed. Further, we did not identify permanent failures for any chips in the time needed to perform tomography for counterfeit detection (approximately 2 hours).

Clinical Use of Third-Generation 3D Imaging Systems in Endoscopic Surgery—a Systematic Review

2021 ◽  
Author(s):  
Jaime Vilaça ◽  
José Moreira de Azevedo ◽  
Hugo Cardoso Louro ◽  
Jorge Correia Pinto ◽  
Pedro Leão
Keyword(s):  
Systematic Review ◽  
Endoscopic Surgery ◽  
3D Imaging ◽  
Imaging Systems ◽  
Third Generation ◽  
Clinical Use

scholarly journals Accuracy and Reliability of Soft Tissue Landmarks Using Three-Dimensional Imaging in Comparison With Two-Dimensional Cephalometrics: A Systematic Review

2020 ◽  
Vol 54 (4) ◽  
pp. 289-296
Author(s):  
Adeeba Ali ◽  
Anil K. Chandna ◽  
Anshul Munjal
Keyword(s):  
Systematic Review ◽  
Soft Tissue ◽  
3D Imaging ◽  
Soft Tissues ◽  
Three Dimensional ◽  
Database Search ◽  
Cochrane Library ◽  
Two Dimensional ◽  
Imaging Tool ◽  
Electronic Database Search

Background: Concerns about the accuracy and reliability of soft tissue landmarks using two-dimensional (2D) and three-dimensional (3D) imaging. Objective: The aim of the systematic review is to estimate accuracy and reliability of soft tissue landmarks with 2D imaging and 3D imaging for orthodontic diagnosis planning and treatment planning purposes. Data Sources: Electronic database search was performed in MEDLINE via PubMed, Embase via embase.com, and the Cochrane library website. Selection Criteria: The data were extracted according to two protocols based on Centre for Evidence-Based Medicine (CEBM) critical appraisal tools. Next, levels of evidence were categorized into three groups: low, medium, and high. Data Synthesis: Fifty-five publications were found through database search strategies. A total of nine publications were included in this review. Conclusion According to the available literature, 3D imaging modalities were more accurate and reliable as compared to 2D modalities. Cone beam computed tomography (CBCT) was considered the most reliable imaging tool for soft tissues.

scholarly journals Novel metrics and methodology for the characterisation of 3D imaging systems

2017 ◽  
Vol 91 ◽  
pp. 169-177 ◽  
Author(s):  
John R. Hodgson ◽  
Peter Kinnell ◽  
Laura Justham ◽  
Niels Lohse ◽  
Michael R. Jackson
Keyword(s):  
3D Imaging ◽  
Imaging Systems

scholarly journals Performance evaluation of 3D imaging systems based on GD&T

2013 ◽  
Vol 1 (1) ◽  
pp. 9-12 ◽  
Author(s):  
Benjamin Carrier ◽  
David K. MacKinnon ◽  
Luc Cournoyer
Keyword(s):  
Performance Evaluation ◽  
3D Imaging ◽  
Imaging Systems

Performance Enhancement of Gain-Modulated 3D Imaging System by Multi-Pulse Accumulation

2013 ◽  
Vol 475-476 ◽  
pp. 259-262
Author(s):  
Fei Wang
Keyword(s):  
3D Imaging ◽  
Performance Enhancement ◽  
Imaging System ◽  
Imaging Systems ◽  
Laser Imaging ◽  
Range Error ◽  
Accumulation Method ◽  
Accuracy Performance

Range accuracy is one of the key parameters for 3D laser imaging systems. A gain-modulated 3D imaging system employing multi-pulse accumulation method is proposed to improve the range accuracy performance. Experiments results show that the range error decreases exponentially with the number of accumulated laser echoes.

A Novel Method for Automated Acquisition of Tilt Series for Electron Tomography Based on Pre-Calibration of the Specimen Stage

2000 ◽  
Vol 6 (S2) ◽  
pp. 1148-1149
Author(s):  
U. Ziese ◽  
A.H. Janssen ◽  
T.P. van der Krift ◽  
A.G. van Balen ◽  
W.J. de Ruijter ◽  
...  
Keyword(s):  
High Resolution ◽  
3D Reconstruction ◽  
Cell Biology ◽  
Electron Tomography ◽  
Three Dimensional ◽  
Imaging Method ◽  
3D Images ◽  
Tilt Series ◽  
3D Information ◽  
Structural Arrangements

Electron tomography is a three-dimensional (3D) imaging method with transmission electron microscopy (TEM) that provides high-resolution 3D images of structural arrangements. Conventional TEM images are in first approximation mere 2D-projections of a 3D sample under investigation. With electron tomographya series of images is acquired of a sample that is tilted over a large angular range (±70°) with small angular tilt increments (so called tilt-series). For the subsequent 3D-reconstruction, the images of the tilt series are aligned relative to each other and the 3D-reconstruction is computed. Electron tomography is the only technique that can provide true 3D information with nm-scale resolution of individual and unique samples. For (cell) biology and material science applications the availability of high-resolution 3D images of structural arrangements within individual samples provides unique architectural information that cannot be obtained otherwise. Routine application of electron tomography will comprise a major revolutionary step forward in the characterization of complex materials and cellular arrangements.

GD&T-Based Characterization of Short-Range Non-contact 3D Imaging Systems

2012 ◽  
Vol 102 (1-3) ◽  
pp. 56-72 ◽  
Author(s):  
David MacKinnon ◽  
Benjamin Carrier ◽  
Jean-Angelo Beraldin ◽  
Luc Cournoyer
Keyword(s):  
Short Range ◽  
3D Imaging ◽  
Imaging Systems

scholarly journals Concept to Commercialization of an Artifact for Evaluating Three-Dimensional Imaging Systems per ASTM E3125-17

2018 ◽  
Vol 123 ◽  
Author(s):  
Bala Muralikrishnan ◽  
Prem Rachakonda ◽  
Vincent Lee ◽  
Meghan Shilling ◽  
Daniel Sawyer ◽  
...  
Keyword(s):  
3D Imaging ◽  
Three Dimensional ◽  
National Research Council ◽  
Imaging Systems ◽  
Considerable Time ◽  
Spherical Coordinate ◽  
Laser Scanners ◽  
Time Required ◽  
Test Use ◽  
Range Error

The relative-range error test is one of several tests described in the ASTM E3125-2017 standard for performance evaluation of spherical coordinate three-dimensional (3D) imaging systems such as terrestrial laser scanners (TLS). We designed a new artifact, called the plate-sphere target, that allows the realization of the relative-range error tests quickly and efficiently without the need for alignment at each position of the test. Use of a simple planar/plate target requires careful alignment of the target at each position of the relative-range error test, which is labor-intensive and time-consuming. This new artifact significantly reduces the time required to perform the test, from a matter of about 2 h to less than 30 min while resulting in similar test uncertainty values. The plate-sphere target was conceived and initially developed at the National Institute of Standards and Technology (NIST), improved based on feedback from collaborators at the National Research Council (NRC) of Canada and TLS manufacturers, and commercialized by Bal-tec Inc. This new artifact will save users and manufacturers of TLSs considerable time and money.

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