scholarly journals Dye-Doped ZnO Microcapsules for High Throughput and Sensitive Optofluidic Micro-Thermometry

Micromachines ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 100 ◽  
Author(s):  
Najla Ghifari ◽  
Sara Rassouk ◽  
Zain Hayat ◽  
Abdelhafed Taleb ◽  
Adil Chahboun ◽  
...  
Keyword(s):  
Zinc Oxide ◽  
High Throughput ◽  
Fluorescence Intensity ◽  
Droplet Microfluidics ◽  
Microfluidic Channels ◽  
Zno Nanocrystals ◽  
Reference Probe ◽  
Opposite Manner ◽  
Increasing Temperature ◽  
First Time

The main objective of this work is to show the proof of concept of a new optofluidic method for high throughput fluorescence-based thermometry, which enables the measure of temperature inside optofluidic microsystems at the millisecond (ms) time scale (high throughput). We used droplet microfluidics to produce highly monodisperse microspheres from dispersed zinc oxide (ZnO) nanocrystals and doped them with rhodamine B (RhB) or/and rhodamine 6G (Rh6G). The fluorescence intensities of these two dyes are known to depend linearly on temperature but in two opposite manner. Their mixture enables for the construction of reference probe whose fluorescence does not depend practically on temperature. The use of zinc oxide microparticles as temperature probes in microfluidic channels has two main advantages: (i) avoid the diffusion and the adsorption of the dyes inside the walls of the microfluidic channels and (ii) enhance dissipation of the heat generated by the focused incident laser beam thanks to the high thermal conductivity of this material. Our results show that the fluorescence intensity of RhB decreases linearly with increasing temperature at a rate of about −2.2%/°C, in a very good agreement with the literature. In contrast, we observed for the first time a nonlinear change of the fluorescence intensity of Rh6G in ZnO microparticles with a minimum intensity at a temperature equal to 40 °C. This behaviour is reproducible and was observed only with ZnO microparticles doped with Rh6G.

Enhanced piezocapacitive response in zinc oxide tetrapod–poly(dimethylsiloxane) composite dielectric layer for flexible and ultrasensitive pressure sensor

Nanoscale ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 6076-6086
Author(s):  
Gen-Wen Hsieh ◽  
Shih-Rong Ling ◽  
Fan-Ting Hung ◽  
Pei-Hsiu Kao ◽  
Jian-Bin Liu
Keyword(s):  
Zinc Oxide ◽  
Pressure Sensor ◽  
Dielectric Layer ◽  
Pressure Sensors ◽  
Dielectric Matrix ◽  
First Time

Zinc oxide tetrapod is introduced for the first time within a poly(dimethylsiloxane) dielectric matrix for the formation of ultrasensitive piezocapacitive pressure sensors.

Efficient Modulation of Catalytic Performance of Electrocatalytic Nitrogen Reduction with Transition Metal Anchored N/O-codoped Graphene by Coordination Engineering

2021 ◽  
Author(s):  
Xiaolin Wang ◽  
Li-Ming Yang
Keyword(s):  
Nitrogen Fixation ◽  
Transition Metal ◽  
High Throughput ◽  
First Principles ◽  
High Throughput Screening ◽  
Catalytic Performance ◽  
Nitrogen Reduction ◽  
Highly Efficient ◽  
First Time

We for the first time report the discovery of a series of highly efficient electrocatalysts, i.e., transition metal anchored N/O-codoped graphene, for nitrogen fixation via high-throughput screening combined with first-principles...

Inertial-ordering-assisted droplet microfluidics for high-throughput single-cell RNA-sequencing

Lab on a Chip ◽  
2018 ◽  
Vol 18 (5) ◽  
pp. 775-784 ◽  
Author(s):  
Hui-Sung Moon ◽  
Kwanghwi Je ◽  
Jae-Woong Min ◽  
Donghyun Park ◽  
Kyung-Yeon Han ◽  
...  
Keyword(s):  
Single Cell ◽  
Rna Sequencing ◽  
High Throughput ◽  
Droplet Microfluidics ◽  
Single Cell Rna Sequencing ◽  
Spiral Microchannel

We developed a modified high-throughput droplet barcoding technique for single-cell Drop-Seq via introduction of hydrodynamic ordering in a spiral microchannel.

scholarly journals A high-throughput cellulase screening system based on droplet microfluidics

2014 ◽  
Vol 8 (4) ◽  
pp. 041102 ◽  
Author(s):  
Raluca Ostafe ◽  
Radivoje Prodanovic ◽  
W. Lloyd Ung ◽  
David A. Weitz ◽  
Rainer Fischer
Keyword(s):  
High Throughput ◽  
Droplet Microfluidics ◽  
Screening System

Droplet-based microfluidics in biomedical applications

2021 ◽  
Author(s):  
Leyla Amirifar ◽  
Mohsen Besanjideh ◽  
Rohollah Nasiri ◽  
Amir Shamloo ◽  
Fatemeh Nasrollahi ◽  
...  
Keyword(s):  
Drug Delivery ◽  
High Throughput ◽  
Paradigm Shift ◽  
Cell Biology ◽  
Biomedical Applications ◽  
Molecular Detection ◽  
Droplet Microfluidics ◽  
Droplet Generation ◽  
Microfluidic Platforms ◽  
Standard Methods

Abstract Droplet-based microfluidic systems have been employed to manipulate discrete fluid volumes with immiscible phases. Creating the fluid droplets at microscale has led to a paradigm shift in mixing, sorting, encapsulation, sensing, and designing high throughput devices for biomedical applications. Droplet microfluidics has opened many opportunities in microparticle synthesis, molecular detection, diagnostics, drug delivery, and cell biology. In the present review, we first introduce standard methods for droplet generation (i.e., passive and active methods) and discuss the latest examples of emulsification and particle synthesis approaches enabled by microfluidic platforms. Then, the applications of droplet-based microfluidics in different biomedical applications are detailed. Finally, a general overview of the latest trends along with the perspectives and future potentials in the field are provided.

HIGH TEMPERATURE ULTRA HIGH VOLTAGE SIC THYRISTORS

2010 ◽  
Vol 2010 (HITEC) ◽  
pp. 000167-000173
Author(s):  
R. Singh ◽  
S. Creamer ◽  
E. Lieser ◽  
S. Jeliazkov ◽  
S. Sundaresan
Keyword(s):  
High Temperature ◽  
Voltage Drop ◽  
Carrier Lifetimes ◽  
Edge Termination ◽  
Minority Carrier Lifetimes ◽  
Stable Performance ◽  
Switching Characteristics ◽  
High Yields ◽  
Increasing Temperature ◽  
First Time

Through a systematic study, Silicon Carbide Gate Turn Off (GTO) Thyristors with record performance are demonstrated. Several Anode-Gate interdigitation schemes (raster, hex and involute) were explored to investigate their effect on the static as well as switching characteristics. An optimized edge-termination was employed that resulted in the achievement of near-theoretical forward blocking voltages (>8.1kV), and high yields (>60% on 8mm×8mm) on GTO Thyristors with 60μm/5×1014 cm−3 voltage-blocking epitaxial layers. A low differential specific on-resistance of 2.55 mΩ-cm2, and low on-state voltage drop were measured at 500 A/cm2. High Temperature forward I-V and reverse I-V characteristics show extremely stable performance with temperature, in contrast to state-of-the-art Si GTO Thyristors. Turn-on transient characteristics show a stable delay time of about 400 nano-seconds, and a rise-time that decreases with increasing temperature. Detailed high temperature turn-off measurements conducted using Anode-Switched mode was used to extract the value of minority carrier lifetimes as a function of temperature for the first time.

scholarly journals Nonisothermal Kinetic Analysis and AC Conductivity for Polyvinyl Chloride (PVC)/Zinc Oxide (ZnO) Nanocomposite

2020 ◽  
Vol 2020 ◽  
pp. 1-18
Author(s):  
Huda AlFannakh
Keyword(s):  
Thermal Stability ◽  
Zinc Oxide ◽  
Kinetic Analysis ◽  
Zno Nanoparticles ◽  
Ac Conductivity ◽  
Zno Nanoparticle ◽  
Nonisothermal Kinetic ◽  
Increasing Temperature ◽  
Host Polymer ◽  
Nonisothermal Kinetic Analysis

The behavior of polyvinyl chlorine (PVC)/zinc oxide (ZnO) nanoparticles was investigated. To improve the dispersion and distribution of zinc nanoparticles within the host polymer (PVC), they were treated with water before being added to the polymer. The nanocomposite samples were prepared by casting method using different weight ratios of ZnO nanoparticles. The prepared nanocomposite samples were characterized by thermogravimetric analysis (TGA). Both thermal stability and kinetic analysis of the prepared samples were investigated. The ZnO nanoparticles lower the activation energy and decrease the thermal stability of PVC. Kissinger, Flynn-Wall-Ozawa, and Kissinger-Akahira-Sunose models were used in the nonisothermal kinetic analysis of PVC/ZnO nanocomposite samples. The thermal stability behavior due to the addition of zinc oxide nanoparticles was explained and correlated with the behavior of the kinetic parameters of the samples. The AC conductivity as function of frequency and temperature was also investigated. The addition of ZnO nanoparticle increases the AC conductivity, and the temperature-independent region decreased by increasing temperature. Both S and A coefficients were predicted using the Jonscher power law and OriginLab software. The trends of S and A coefficients were discussed based on the glass transition of the host polymer.

The Phenolyzer Suite: Prioritizing the Candidate Genes Involved in Microtia

2019 ◽  
Vol 128 (6) ◽  
pp. 556-562 ◽  
Author(s):  
Huang Xin ◽  
Wang Changchen ◽  
Liu Lei ◽  
Yang Meirong ◽  
Zhang Ye ◽  
...  
Keyword(s):  
Candidate Genes ◽  
High Throughput ◽  
Potential Candidate ◽  
Single Nucleotide Variants ◽  
Gene Score ◽  
Single Nucleotide ◽  
Research Directions ◽  
Score System ◽  
Pathogenic Genes ◽  
First Time

Objective: Microtia is a congenital malformation of the external ear. Great progress about the genetic of microtia has been made in recent years. This article was to prioritize the potential candidate pathogenic genes of microtia based on existing studies and reports, with the purpose of narrowing the range of following study scientifically and quickly. Method: A computational tool called Phenolyzer (phenotype-based gene analyzer) was used to prioritize microtia genes. Microtia, as a query term, was input in the interface of Phenolyzer. After several steps, including disease match, gene query, gene score system, seed gene growth, and gene ranking, the final results about genetic information of microtia were provided. Then we tracked details of the top 10 genes ranked by Phenolyzer on the basis of previous reports. Results: We detected 10 348 genes associated with microtia or related syndromes, and 78 genes of those genes belonged to seed genes. Every gene was given a score, and the gene with higher scores was more likely influence microtia. The top 10 ranked genes included HOXA2, CHD7, CDT1, ORC1, ORC4, ORC6, CDC6, MED12, TWIST1, and GLI3. Otherwise, four gene-gene interactions were displayed. Conclusion: This article prioritized candidate genes of microtia for the first time. High-throughput methods provide tens of thousands of single-nucleotide variants, indels, and structural variants, and only a handful are relevant to microtia or associated syndromes. Combine the ranked potential pathogenic genes list from Phenolyzer with the results of samples provided by high-throughput methods, and more precise research directions are presented.

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