scholarly journals 3D Printed Multi-Functional Hydrogel Microneedles Based on High-Precision Digital Light Processing

Micromachines ◽  
2019 ◽  
Vol 11 (1) ◽  
pp. 17 ◽  
Author(s):  
Wei Yao ◽  
Didi Li ◽  
Yuliang Zhao ◽  
Zhikun Zhan ◽  
Guoqing Jin ◽  
...  
Keyword(s):  
High Precision ◽  
Clinical Medicine ◽  
Mechanical Performance ◽  
Low Cost ◽  
Critical Parameters ◽  
Fast Method ◽  
Drug Injection ◽  
Digital Light Processing ◽  
Drug Detection ◽  
The Cost

Traditional injection and extraction devices often appear painful and cumbersome for patients. In recent years, polymer microneedles (MNs) have become a novel tool in the field of clinical medicine and health. However, the cost of building MNs into any shapes still remains a challenge. In this paper, we proposed hydrogel microneedles fabricated by high-precision digital light processing (H-P DLP) 3D printing system. Benefits from the sharp protuberance and micro-porous of the hydrogel microneedle, the microneedle performed multifunctional tasks such as drug delivery and detection with minimally invasion. Critical parameters for the fabrication process were analyzed, and the mechanical properties of MNs were measured to find a balance between precision and stiffness. Results shows that the stiffness and precision were significantly influenced by exposure time of each layer, and optimized printing parameters provided a balance between precision and stiffness. Bio-compatible MNs based on our H-P DLP system was able to execute drug injection and drug detection in our experiments. This work provided a low-cost and fast method to build MNs with 3D building, qualified the mechanical performance, drug injection, drug detection ability of MNs, and may be helpful for the potential clinical application.

Mechanical Properties of ABS Embedded with Basalt Fiber Fillers

2016 ◽  
Vol 16 (2) ◽  
pp. 69-74 ◽  
Author(s):  
Ayman M. M. Abdelhaleem ◽  
Mohammed Y. Abdellah ◽  
Hesham I. Fathi ◽  
Montasser Dewidar
Keyword(s):  
Mechanical Properties ◽  
Mechanical Performance ◽  
Low Cost ◽  
Basalt Fiber ◽  
Acrylonitrile Butadiene Styrene ◽  
Hardness Test ◽  
Basalt Fibers ◽  
Notched Strength ◽  
The Cost ◽  
Plastic Injection

AbstractAcrylonitrile-butadiene-styrene (ABS) has great verity applications in aerospace and automobiles industries. Mechanical strength of the ABS is superior to even that of impact resistant polystyrene. In addition metallic coatings can be applied to the surface of ABS moldings. The main aim of the present work is to investigate the mechanical properties of additives of basalt fibers (BF) to ABS with (5, 10, and 15) wt% embedded into the polymer matrix by using plastic injection molding technique. This new perceptions has been done on basalt fibers that have a potential low cost with its good mechanical performance. The ultimate tensile strength that obtained from the composite with 15 wt% is 56.67 MPa with 40.52 % increase value than neat ABS, Young’s modulus gradually increases with increasing the amount of additives. Impact un-notched strength decreases with a reported increment of 24.617 KJ.m–2. A Rockwell hardness test is also used and with the increases of additives the amount of hardness of the composite increases. A scan electron microscopy (SEM) on the fracture surface is captured to check the morphologies structure of the composite comparable with a neat ABS. and it is showed a very good distribution and bonding of the B.F. with the pure ABS. As well as the cost of the ABS and BF is reduced by a percentage of 15 %.

Lapping Parabolic Parts Using the Bending Lapping Tool

2014 ◽  
Vol 900 ◽  
pp. 592-595
Author(s):  
Chun Min Shang ◽  
Dong Mei Zhang ◽  
Jian Dong Yang
Keyword(s):  
High Precision ◽  
Low Cost ◽  
New Technology ◽  
Experimental Result ◽  
Work Piece ◽  
Face Shape ◽  
Minimal Error ◽  
Shape Precision ◽  
The Cost ◽  
Easy Operation

Lapping the parabolic work-piece with the lapping tool in bending method is a new technology, which has some good characters such as low cost, scope broad, easy operation, and high precision. The lapping tool is formed by the means of bending and forming with solid abrasives on it in the experiment. The experiment shows that parabolic workpiece can be lapped using this method. The experimental result indicates that the work-piece face shape precision is high with the lapping tool, the maximal error is 0.0881mm and the minimal error is-0.0011mm, and lapping efficiency is high and the cost is low.

scholarly journals Fabrication of Graphene-Reinforced Nanocomposites with Improved Fracture Toughness in Net Shape for Complex 3D Structures via Digital Light Processing

2019 ◽  
Vol 5 (2) ◽  
pp. 25 ◽  
Author(s):  
Zuying Feng ◽  
Yan Li ◽  
Chenxing Xin ◽  
Danna Tang ◽  
Wei Xiong ◽  
...  
Keyword(s):  
Fracture Toughness ◽  
Tissue Engineering ◽  
Low Cost ◽  
Flexural Modulus ◽  
Thermomechanical Properties ◽  
Neat Resin ◽  
Digital Light Processing ◽  
Complex Skill ◽  
Graphene Nanocomposite ◽  
The Cost

A solvent-free method to fabricate graphene-reinforced nanocomposites in net shape via digital light processing (DLP) 3D printing has been developed in this work. The effect of graphene nanofillers on resin viscosity and wettability for various printing parameters has been examined, with a systematic characterization of the mechanical and thermomechanical properties. With the addition of 0.5 wt.% graphene nanoplatelets in the resin, the flexural modulus and fracture toughness have been improved by 14% and 28% from neat resin, respectively. Thermomechanical properties of graphene-reinforced nanocomposites were also enhanced compared with the neat resin, without scarification in their printability. The feasibility of utilizing the DLP method to fabricate a fracture toughness specimen (KIC test) without complex skill-dependent notch preparation steps was explored, with different notch tip angles printed for net-shaped specimens. This provided a simple and versatile way to perform a quick examination of reinforcing efficiency from nanofillers at very low cost with high resolution and reproducibility. To demonstrate the suitability of current resins for complexly shaped structures, a gyroid scaffold for tissue engineering applications based on current graphene nanocomposite resins has been successfully fabricated via DLP, showing the great potential of current photocurable resins for applications in various fields such as tissue engineering or personalized medical devices without the cost barriers of traditional methods.

Advance Protection for Three Phase Induction Motor using Microcontroller Atmega32

2018 ◽  
Vol 8 (1) ◽  
pp. 172
Author(s):  
Karan S Belsare ◽  
Gajanan D Patil
Keyword(s):  
Induction Motor ◽  
Low Cost ◽  
Short Circuit ◽  
Cost Factor ◽  
Protection Scheme ◽  
Three Phase ◽  
The Cost

A low cost and reliable protection scheme has been designed for a three phase induction motor against unbalance voltages, under voltage, over voltage, short circuit and overheating protection. Taking the cost factor into consideration the design has been proposed using microcontroller Atmega32, MOSFETs, relays, small CTs and PTs. However the sensitivity of the protection scheme has been not compromised. The design has been tested online in the laboratory for small motors and the same can be implemented for larger motors by replacing the i-v converters and relays of suitable ratings.

Janus – A New Approach to Air Combat Pilot Training

2019 ◽  
Vol 2019 (4) ◽  
pp. 7-22
Author(s):  
Georges Bridel ◽  
Zdobyslaw Goraj ◽  
Lukasz Kiszkowiak ◽  
Jean-Georges Brévot ◽  
Jean-Pierre Devaux ◽  
...  
Keyword(s):  
Low Cost ◽  
Cost Effective ◽  
High Energy ◽  
Training System ◽  
Embedded Sensors ◽  
Pilot Training ◽  
New Approach ◽  
Combat Aircraft ◽  
Air Combat ◽  
The Cost

Abstract Advanced jet training still relies on old concepts and solutions that are no longer efficient when considering the current and forthcoming changes in air combat. The cost of those old solutions to develop and maintain combat pilot skills are important, adding even more constraints to the training limitations. The requirement of having a trainer aircraft able to perform also light combat aircraft operational mission is adding unnecessary complexity and cost without any real operational advantages to air combat mission training. Thanks to emerging technologies, the JANUS project will study the feasibility of a brand-new concept of agile manoeuvrable training aircraft and an integrated training system, able to provide a live, virtual and constructive environment. The JANUS concept is based on a lightweight, low-cost, high energy aircraft associated to a ground based Integrated Training System providing simulated and emulated signals, simulated and real opponents, combined with real-time feedback on pilot’s physiological characteristics: traditionally embedded sensors are replaced with emulated signals, simulated opponents are proposed to the pilot, enabling out of sight engagement. JANUS is also providing new cost effective and more realistic solutions for “Red air aircraft” missions, organised in so-called “Aggressor Squadrons”.

scholarly journals A low-cost wireless endoscope camera: a preliminary report

2021 ◽  
Vol 27 (1) ◽  
Author(s):  
J. M. Lazarus ◽  
M. Ncube
Keyword(s):  
Minimally Invasive Surgery ◽  
Minimally Invasive ◽  
Video Transmission ◽  
Low Cost ◽  
Battery Life ◽  
Resource Constrained ◽  
High Definition ◽  
Industry Standard ◽  
Constrained Environments ◽  
The Cost

Abstract Background Technology currently used for surgical endoscopy was developed and is manufactured in high-income economies. The cost of this equipment makes technology transfer to resource constrained environments difficult. We aimed to design an affordable wireless endoscope to aid visualisation during rigid endoscopy and minimally invasive surgery (MIS). The initial prototype aimed to replicate a 4-mm lens used in rigid cystoscopy. Methods Focus was placed on using open-source resources to develop the wireless endoscope to significantly lower the cost and make the device accessible for resource-constrained settings. An off the shelf miniature single-board computer module was used because of its low cost (US$10) and its ability to handle high-definition (720p) video. Open-source Linux software made monitor mode (“hotspot”) wireless video transmission possible. A 1280 × 720 pixel high-definition tube camera was used to generate the video signal. Video is transmitted to a standard laptop computer for display. Bench testing included latency of wireless digital video transmission. Comparison to industry standard wired cameras was made including weight and cost. The battery life was also assessed. Results In comparison with industry standard cystoscope lens, wired camera, video processing unit and light source, the prototype costs substantially less. (US$ 230 vs 28 000). The prototype is light weight (184 g), has no cables tethering and has acceptable battery life (of over 2 h, using a 1200 mAh battery). The camera transmits video wirelessly in near real time with only imperceptible latency of < 200 ms. Image quality is high definition at 30 frames per second. Colour rendering is good, and white balancing is possible. Limitations include the lack of a zoom. Conclusion The novel wireless endoscope camera described here offers equivalent high-definition video at a markedly reduced cost to contemporary industry wired units and could contribute to making minimally invasive surgery possible in resource-constrained environments.

scholarly journals Sunflower-Like Nanostructure with Built-In Hotspots for Alpha-Fetoprotein Detection

Molecules ◽  
2021 ◽  
Vol 26 (4) ◽  
pp. 1197
Author(s):  
Xiaoyu Zhao ◽  
Aonan Zhu ◽  
Yaxin Wang ◽  
Yongjun Zhang ◽  
Xiaolong Zhang
Keyword(s):  
Rapid Detection ◽  
Clinical Medicine ◽  
Electromagnetic Coupling ◽  
Low Cost ◽  
Surface Enhanced Raman Spectroscopy ◽  
Alpha Fetoprotein ◽  
Low Concentrations ◽  
Surface Enhanced Raman ◽  
Active Substrate ◽  
Array Structures

In the present study, a sunflower-like nanostructure array composed of a series of synaptic nanoparticles and nanospheres was manufactured through an efficient and low-cost colloidal lithography technique. The primary electromagnetic field contribution generated by the synaptic nanoparticles of the surface array structures was also determined by a finite-difference time-domain software to simulate the hotspots. This structure exhibited high repeatability and excellent sensitivity; hence, it was used as a surface-enhanced Raman spectroscopy (SERS) active substrate to achieve a rapid detection of ultra-low concentrations of Alpha-fetoprotein (AFP). This study demonstrates the design of a plasmonic structure with strong electromagnetic coupling, which can be used for the rapid detection of AFP concentration in clinical medicine.

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