scholarly journals Hybrid Two-Scale Fabrication of Sub-Millimetric Capillary Grippers

Micromachines ◽  
2019 ◽  
Vol 10 (4) ◽  
pp. 224 ◽  
Author(s):  
Sam Dehaeck ◽  
Marco Cavaiani ◽  
Adam Chafai ◽  
Youness Tourtit ◽  
Youen Vitry ◽  
...  

Capillary gripping is a pick-and-place technique that is particularly well-suited for handling sub-millimetric components. Nevertheless, integrating a fluid supply and release mechanism becomes increasingly difficult to manufacture for these scales. In the present contribution, two hybrid manufacturing procedures are introduced in which the creation of the smallest features is decoupled from the macro-scale components. In the first procedure, small scale features are printed directly (by two-photon polymerisation) on top of a 3D-printed device (through stereolithography). In the second approach, directional ultraviolet (UV)-illumination and an adapted design allowed for successful (polydimethylsiloxane, PDMS) moulding of the microscopic gripper head on top of a metal substrate. Importantly, a fully functional microchannel is present in both cases through which liquid to grip the components can be supplied and retracted. This capability of removing the liquid combined with an asymmetric pillar design allows for a passive release mechanism with a placement precision on the order of 3% of the component size.

2020 ◽  
Vol 32 (52) ◽  
pp. 2070388
Author(s):  
Simone Gervasoni ◽  
Anastasia Terzopoulou ◽  
Carlos Franco ◽  
Andrea Veciana ◽  
Norman Pedrini ◽  
...  

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Michał Ziemczonok ◽  
Arkadiusz Kuś ◽  
Piotr Wasylczyk ◽  
Małgorzata Kujawińska

AbstractAs the 3D quantitative phase imaging (QPI) methods mature, their further development calls for reliable tools and methods to characterize and compare their metrological parameters. We use refractive index engineering during two-photon laser photolithography to fabricate a life-scale phantom of a biological cell with internal structures that mimic optical and structural properties of mammalian cells. After verification with a number of reference techniques, the phantom is used to characterize the performance of a limited-angle holographic tomography microscope.


1988 ◽  
Vol 127 ◽  
Author(s):  
Hans G. Scheibel ◽  
V. Friehmelt ◽  
H. Froehlich

ABSTRACTThe fracture and release mechanism of radioactive aerosols of HLW glass and HLW canisters are studied experimentally by laboratory scale and full scale drop tests. The experimental conditions model the conditions of accidental drops in a deep salt repository. The laboratory scale drop tests have a scaling factor of 1:10. Accelerated probes of simulated HLW glass impact on a ground plate and the size distributions of broken fines and released aerosols are measured by sieving and scanning electron microscopy (SEM) of aerosol samples.The impact velocity is determined as the dominating impact parameter. Further parameters tested, such as waste glass composition, cooling time (residual thermal stresses), probe temperature at impact, and ground characteristics, show no measurable influence. Source terms of released respirable aerosols are evaluated for two reference cases, borehole drop (impact velocity v = 80 m/s) and reloading hall drop (v = 14 m/s), the values being 0.1 % and to 2.10-4 % respectively of the glass probe mass. The full scale drop tests are performed with European Standard HLW canisters. The canisters keep their integrity in all tests up to drop heights of 14 m. On opening the canisters, the broken fines are analyzed by sieving. The results are in good agreement with the small scale tests and confirm their acceptability for use in a safety analysis.


Author(s):  
Yan Cui ◽  
John C. Wells

Experiments on sedimentary ripples in rotating cylinders have been considered as a convenient configuration for studying ripples. This system is simple and convenient to study sediment transport compared to the traditional channel experiments. In the present contribution, we conduct a small scale experiment as a “benchmark” of our numerical model. Processes of pattern formations have been produced and the results of the spiral arm properties are compared to the published experimental data.


Author(s):  
Ronan Grimes ◽  
David Quin ◽  
Edmond Walsh ◽  
Jeff Punch

The emergence of highly functional portable electronic systems in recent times means that passive dissipation of heat in these devices may not be an option in the near future. Micro fan technology is currently being developed to address this emerging need. Past investigations by the current authors indicate that the reduction of scale of conventional electronics cooling fan design to the mini scale does not excessively impair the bulk pressure flow performance of the fan. However, the detailed velocity distribution at the outlet of mini scale axial flow fans is unknown, and so effective thermal design in systems which use mini scale fans may be difficult, as the designer does not know the path taken by the flow emerging from the fan. To address this issue, this paper presents PIV measurements performed at the outlet of a series of geometrically similar axial flow fans, whose diameters range from 120 to 6mm, and whose design is based on that of a commercially available macro scale electronics cooling fan. The measurements show that as fan scale is reduced, there is a significant change in the fan outlet velocity distribution, and a large increase in the outlet radial flow angle. As a result, a designer using a small scale axial flow fan must be aware that the region downstream of the fan, where one would normally expect high velocity flow, will in fact be uncooled. Therefore, components should be mounted radially downstream of the fan, where highest air velocities are shown to exist.


Author(s):  
Izhak Bucher ◽  
Eyal Setter

Micro-scale slender swimmers are frequently encountered in nature and recently in micro-robotic applications. The swimming mechanism examined in this article is based on small transverse axi-symmetrical travelling wave deformations of a cylindrical long shell. In very small scale, inertia forces become negligible and viscous forces dominate most propulsion mechanisms being used by micro-organisms and robotic devices. The present paper proposes a compact design principle that provides efficient power to propel and maneuver a micro-scale device. Shown in this paper is a numerical analysis which couples the MEMS structure to the surrounding fluid. Analytical results compare the proposed mechanism to commonly found tail (flagella) driven devices, and a parametric comparison is shown suggesting it has superior performance. Numerical studies are preformed to verify the analytical model. Finally, a macro-scale demonstrator swimming in an environment with similar Reynolds numbers to the ones found in small scale is shown and its behavior in the laboratory is compared to the theory.


2012 ◽  
Vol 32 (7) ◽  
pp. 1277-1309 ◽  
Author(s):  
Andy Y Shih ◽  
Jonathan D Driscoll ◽  
Patrick J Drew ◽  
Nozomi Nishimura ◽  
Chris B Schaffer ◽  
...  

The cerebral vascular system services the constant demand for energy during neuronal activity in the brain. Attempts to delineate the logic of neurovascular coupling have been greatly aided by the advent of two-photon laser scanning microscopy to image both blood flow and the activity of individual cells below the surface of the brain. Here we provide a technical guide to imaging cerebral blood flow in rodents. We describe in detail the surgical procedures required to generate cranial windows for optical access to the cortex of both rats and mice and the use of two-photon microscopy to accurately measure blood flow in individual cortical vessels concurrent with local cellular activity. We further provide examples on how these techniques can be applied to the study of local blood flow regulation and vascular pathologies such as small-scale stroke.


2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Friedrich Ihler ◽  
Mattis Bertlich ◽  
Bernhard Weiss ◽  
Steffen Dietzel ◽  
Martin Canis

Impairment of cochlear blood flow has been discussed as factor in the pathophysiology of various inner ear disorders. However, the microscopic study of cochlear microcirculation is limited due to small scale and anatomical constraints. Here, two-photon fluorescence microscopy is applied to visualize cochlear microvessels. Guinea pigs were injected with Fluorescein isothiocyanate- or Texas red-dextrane as plasma marker. Intravital microscopy was performed in four animals and explanted cochleae from four animals were studied. The vascular architecture of the cochlea was visualized up to a depth of90.0±22.7 μm. Imaging yielded a mean contrast-to-noise ratio (CNR) of3.3±1.7. Mean diameter in vivo was16.5±6.0 μm for arterioles and8.0±2.4 μm for capillaries. In explanted cochleae, the diameter of radiating arterioles and capillaries was measured with12.2±1.6 μm and6.6±1.0 μm, respectively. The difference between capillaries and arterioles was statistically significant in both experimental setups (P<0.001andP=0.022, two-way ANOVA). Measured vessel diameters in vivo and ex vivo were in agreement with published data. We conclude that two-photon fluorescence microscopy allows the investigation of cochlear microvessels and is potentially a valuable tool for inner ear research.


2015 ◽  
Vol 4 (1) ◽  
pp. 27-36 ◽  
Author(s):  
Nadiia Mameka ◽  
Ke Wang ◽  
Jürgen Markmann ◽  
Erica T. Lilleodden ◽  
Jörg Weissmüller

Author(s):  
Hassan Gonabadi ◽  
Yao Chen ◽  
Arti Yadav ◽  
Steve Bull

AbstractAlthough the literature is abundant with the experimental methods to characterize mechanical behavior of parts made by fused filament fabrication 3D printing, less attention has been paid in using computational models to predict the mechanical properties of these parts. In the present paper, a numerical homogenization technique is developed to predict the effect of printing process parameters on the elastic response of 3D printed parts with cellular lattice structures. The development of finite element computational models of printed parts is based on a multi scale approach. Initially, at the micro scale level, the analysis of micro-mechanical models of a representative volume element is used to calculate the effective orthotropic properties. The finite element models include different infill densities and building/raster orientation maintaining the bonded region between the adjacent fibers and layers. The elastic constants obtained by this method are then used as an input for the creation of macro scale finite element models enabling the simulation of the mechanical response of printed samples subjected to the bending, shear, and tensile loads. Finally, the results obtained by the homogenization technique are validated against more realistic finite element explicit microstructural models and experimental measurements. The results show that, providing an accurate characterization of the properties to be fed into the macro scale model, the use of the homogenization technique is a reliable tool to predict the elastic response of 3D printed parts. The outlined approach provides faster iterative design of 3D printed parts, contributing to reducing the number of experimental replicates and fabrication costs.


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