scholarly journals Development of a New Laparoscopic Detection System for Gastric Cancer Using Near-Infrared Light-Emitting Clips with Glass Phosphor

Micromachines ◽  
2019 ◽  
Vol 10 (2) ◽  
pp. 81
Author(s):  
Shunko Inada ◽  
Hayao Nakanishi ◽  
Masahiro Oda ◽  
Kensaku Mori ◽  
Akihiro Ito ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Laparoscopic Surgery ◽  
Near Infrared ◽  
Detection System ◽  
Fluorescent Detection ◽  
Infrared Light ◽  
Excitation Light ◽  
Light Emitting ◽  
Nir Light ◽  
Glass Phosphor

Laparoscopic surgery is now a standard treatment for gastric cancer. Currently, the location of the gastric cancer is identified during laparoscopic surgery via the preoperative endoscopic injection of charcoal ink around the primary tumor; however, the wide spread of injected charcoal ink can make it difficult to accurately visualize the specific site of the tumor. To precisely identify the locations of gastric tumors, we developed a fluorescent detection system comprising clips with glass phosphor (Yb3+, Nd3+ doped to Bi2O3-B2O3-based glasses, size: 2 mm × 1 mm × 3 mm) fixed in the stomach and a laparoscopic fluorescent detection system for clip-derived near-infrared (NIR) light (976 nm). We conducted two ex vivo experiments to evaluate the performance of this fluorescent detection system in an extirpated pig stomach and a freshly resected human stomach and were able to successfully detect NIR fluorescence emitted from the clip in the stomach through the stomach wall by the irradiation of excitation light (λ: 808 nm). These results suggest that the proposed combined NIR light-emitting clip and laparoscopic fluorescent detection system could be very useful in clinical practice for accurately identifying the location of a primary gastric tumor during laparoscopic surgery.

Catalyst Halogenation Enables Rapid and Efficient Polymerizations with Visible to Near-Infrared Light

2020 ◽  
Author(s):  
Alex Stafford ◽  
Dowon Ahn ◽  
Emily Raulerson ◽  
Kun-You Chung ◽  
Kaihong Sun ◽  
...  
Keyword(s):  
Near Infrared ◽  
Transient Absorption ◽  
Reaction Times ◽  
Infrared Light ◽  
Structure Property ◽  
Light Emitting ◽  
Structure Property Relationships ◽  
Nir Light ◽  
Light Intensities ◽  
Emission Quenching

Driving rapid polymerizations with visible to near-infrared (NIR) light will enable nascent technologies in the emerging fields of bio- and composite-printing. However, current photopolymerization strategies are limited by long reaction times, high light intensities, and/or large catalyst loadings. Improving efficiency remains elusive without a comprehensive, mechanistic evaluation of photocatalysis to better understand how composition relates to polymerization metrics. With this objective in mind, a series of methine- and aza-bridged boron dipyrromethene (BODIPY) derivatives were synthesized and systematically characterized to elucidate key structure-property relationships that facilitate efficient photopolymerization driven by visible to NIR light. For both BODIPY scaffolds, halogenation was shown as a general method to increase polymerization rate, quantitatively characterized using a custom real-time infrared spectroscopy setup. Furthermore, a combination of steady-state emission quenching experiments, electronic structure calculations, and ultrafast transient absorption revealed that efficient intersystem crossing to the lowest excited triplet state upon halogenation was a key mechanistic step to achieving rapid photopolymerization reactions. Unprecedented polymerization rates were achieved with extremely low light intensities (< 1 mW/cm<sup>2</sup>) and catalyst loadings (< 50 μM), exemplified by reaction completion within 60 seconds of irradiation using green, red, and NIR light-emitting diodes.

Development of new devices for detection of gastric cancer on laparoscopic surgery using near-infrared light

2015 ◽  
Author(s):  
Shunko A. Inada ◽  
Shingo Fuchi ◽  
Kensaku Mori ◽  
Junichi Hasegawa ◽  
Kazunari Misawa ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Laparoscopic Surgery ◽  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light ◽  
New Devices

Near-Infrared Light Emitting Diode Based Non-Invasive Glucose Detection System

2019 ◽  
Vol 19 (10) ◽  
pp. 6187-6191 ◽  
Author(s):  
Seung Ho Lee ◽  
Min Seok Kim ◽  
Ok-Kyun Kim ◽  
Hyung-Hwan Baik ◽  
Ji-Hye Kim
Keyword(s):  
Near Infrared ◽  
Detection System ◽  
Light Emitting Diode ◽  
Infrared Light ◽  
Glucose Detection ◽  
Near Infrared Light ◽  
Light Emitting ◽  
Non Invasive

scholarly journals Catalyst Halogenation Enables Rapid and Efficient Polymerizations with Visible to Near-Infrared Light

2020 ◽  
Author(s):  
Alex Stafford ◽  
Dowon Ahn ◽  
Emily Raulerson ◽  
Kun-You Chung ◽  
Kaihong Sun ◽  
...  
Keyword(s):  
Near Infrared ◽  
Transient Absorption ◽  
Reaction Times ◽  
Infrared Light ◽  
Structure Property ◽  
Light Emitting ◽  
Structure Property Relationships ◽  
Nir Light ◽  
Light Intensities ◽  
Emission Quenching

Driving rapid polymerizations with visible to near-infrared (NIR) light will enable nascent technologies in the emerging fields of bio- and composite-printing. However, current photopolymerization strategies are limited by long reaction times, high light intensities, and/or large catalyst loadings. Improving efficiency remains elusive without a comprehensive, mechanistic evaluation of photocatalysis to better understand how composition relates to polymerization metrics. With this objective in mind, a series of methine- and aza-bridged boron dipyrromethene (BODIPY) derivatives were synthesized and systematically characterized to elucidate key structure-property relationships that facilitate efficient photopolymerization driven by visible to NIR light. For both BODIPY scaffolds, halogenation was shown as a general method to increase polymerization rate, quantitatively characterized using a custom real-time infrared spectroscopy setup. Furthermore, a combination of steady-state emission quenching experiments, electronic structure calculations, and ultrafast transient absorption revealed that efficient intersystem crossing to the lowest excited triplet state upon halogenation was a key mechanistic step to achieving rapid photopolymerization reactions. Unprecedented polymerization rates were achieved with extremely low light intensities (< 1 mW/cm<sup>2</sup>) and catalyst loadings (< 50 μM), exemplified by reaction completion within 60 seconds of irradiation using green, red, and NIR light-emitting diodes.

Near-infrared light-emitting electrochemical cells based on the excimer emission of a cationic iridium complex

2020 ◽  
Vol 8 (41) ◽  
pp. 14378-14385
Author(s):  
You-Xuan Liu ◽  
Rong-Huei Yi ◽  
Chien-Hsiang Lin ◽  
Zu-Po Yang ◽  
Chin-Wei Lu ◽  
...  
Keyword(s):  
Organic Semiconductors ◽  
Near Infrared ◽  
Night Vision ◽  
Infrared Light ◽  
Iridium Complex ◽  
Electrochemical Cells ◽  
Light Emitting ◽  
Light Emitting Devices ◽  
Nir Light ◽  
Bio Imaging

Near-infrared (NIR) light-emitting devices with organic semiconductors have great potential for applications in bio-imaging, telecommunication, night-vision displays, and chemical sensing.

scholarly journals Two-dimensional perovskites with alternating cations in the interlayer space for stable light-emitting diodes

Nanophotonics ◽  
2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Yiyue Zhang ◽  
Masoumeh Keshavarz ◽  
Elke Debroye ◽  
Eduard Fron ◽  
Miriam Candelaria Rodríguez González ◽  
...  
Keyword(s):  
Thin Films ◽  
Near Infrared ◽  
Light Emitting Diodes ◽  
Interlayer Space ◽  
High Current Density ◽  
Operational Stability ◽  
Infrared Light ◽  
Two Dimensional ◽  
Commercial Development ◽  
Light Emitting

Abstract Lead halide perovskites have attracted tremendous attention in photovoltaics due to their impressive optoelectronic properties. However, the poor stability of perovskite-based devices remains a bottleneck for further commercial development. Two-dimensional perovskites have great potential in optoelectronic devices, as they are much more stable than their three-dimensional counterparts and rapidly catching up in performance. Herein, we demonstrate high-quality two-dimensional novel perovskite thin films with alternating cations in the interlayer space. This innovative perovskite provides highly stable semiconductor thin films for efficient near-infrared light-emitting diodes (LEDs). Highly efficient LEDs with tunable emission wavelengths from 680 to 770 nm along with excellent operational stability are demonstrated by varying the thickness of the interlayer spacer cation. Furthermore, the best-performing device exhibits an external quantum efficiency of 3.4% at a high current density (J) of 249 mA/cm2 and remains above 2.5% for a J up to 720 mA cm−2, leading to a high radiance of 77.5 W/Sr m2 when driven at 6 V. The same device also shows impressive operational stability, retaining almost 80% of its initial performance after operating at 20 mA/cm2 for 350 min. This work provides fundamental evidence that this novel alternating interlayer cation 2D perovskite can be a promising and stable photonic emitter.

Heat-resistant reflectors for enhanced 850-nm near infrared light-emitting diode efficiency

2021 ◽  
pp. 103879
Author(s):  
Hyung-Joo Lee ◽  
Gwang-Hoon Park ◽  
Jin-Su So ◽  
Choong-Hun Lee ◽  
Jae-Hoon Kim ◽  
...  
Keyword(s):  
Near Infrared ◽  
Light Emitting Diode ◽  
Infrared Light ◽  
Near Infrared Light ◽  
Light Emitting ◽  
Heat Resistant

scholarly journals Amelioration of oral mucositis pain by NASA near-infrared light-emitting diodes in bone marrow transplant patients

2011 ◽  
Vol 20 (7) ◽  
pp. 1405-1415 ◽  
Author(s):  
Brian D. Hodgson ◽  
David M. Margolis ◽  
Donna E. Salzman ◽  
Dan Eastwood ◽  
Sergey Tarima ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Marrow Transplant ◽  
Oral Mucositis ◽  
Near Infrared ◽  
Light Emitting Diodes ◽  
Marrow Transplant ◽  
Infrared Light ◽  
Near Infrared Light ◽  
Light Emitting ◽  
Transplant Patients

scholarly journals Photothermal Therapy Using Gold Nanorods and Near-Infrared Light in a Murine Melanoma Model Increases Survival and Decreases Tumor Volume

2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Mary K. Popp ◽  
Imane Oubou ◽  
Colin Shepherd ◽  
Zachary Nager ◽  
Courtney Anderson ◽  
...  
Keyword(s):  
Light Source ◽  
Gold Nanorods ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Tumor Volume ◽  
Infrared Light ◽  
Led Light ◽  
Murine Melanoma ◽  
Nir Light ◽  
Melanoma Model

Photothermal therapy (PTT) treatments have shown strong potential in treating tumors through their ability to target destructive heat preferentially to tumor regions. In this paper we demonstrate that PTT in a murine melanoma model using gold nanorods (GNRs) and near-infrared (NIR) light decreases tumor volume and increases animal survival to an extent that is comparable to the current generation of melanoma drugs. GNRs, in particular, have shown a strong ability to reach ablative temperatures quickly in tumors when exposed to NIR light. The current research tests the efficacy of GNRs PTT in a difficult and fast growing murine melanoma model using a NIR light-emitting diode (LED) light source. LED light sources in the NIR spectrum could provide a safer and more practical approach to photothermal therapy than lasers. We also show that the LED light source can effectively and quickly heatin vitroandin vivomodels to ablative temperatures when combined with GNRs. We anticipate that this approach could have significant implications for human cancer therapy.

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