scholarly journals The Seaweed Diet in Prevention and Treatment of the Neurodegenerative Diseases

Marine Drugs ◽  
2021 ◽  
Vol 19 (3) ◽  
pp. 128
Author(s):  
Leonel Pereira ◽  
Ana Valado
Keyword(s):  
Multiple Sclerosis ◽  
Fatty Acids ◽  
Neurodegenerative Diseases ◽  
Marine Algae ◽  
Gelling Agents ◽  
Prevention And Treatment ◽  
Pharmaceutical Industries ◽  
Therapeutic Properties ◽  
Main Components ◽  
Long Chain

Edible marine algae are rich in bioactive compounds and are, therefore, a source of bioavailable proteins, long chain polysaccharides that behave as low-calorie soluble fibers, metabolically necessary minerals, vitamins, polyunsaturated fatty acids, and antioxidants. Marine algae were used primarily as gelling agents and thickeners (phycocolloids) in food and pharmaceutical industries in the last century, but recent research has revealed their potential as a source of useful compounds for the pharmaceutical, medical, and cosmetic industries. The green, red, and brown algae have been shown to have useful therapeutic properties in the prevention and treatment of neurodegenerative diseases: Parkinson, Alzheimer’s, and Multiple Sclerosis, and other chronic diseases. In this review are listed and described the main components of a suitable diet for patients with these diseases. In addition, compounds derived from macroalgae and their neurophysiological activities are described.

Distribution of long chain aldehyde-forming activity from fatty acids and changes in its activity with growth in marine algae

1992 ◽  
Vol 31 (8) ◽  
pp. 2635-2639 ◽  
Author(s):  
Tadahiko Kajiwara ◽  
Akikazu Hatanaka ◽  
Kenji Matsui ◽  
Takashi Tomoi ◽  
Taichiro Fujimura ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Marine Algae ◽  
Long Chain ◽  
Chain Aldehyde

The Influence of Vitamin D on Neurodegeneration and Neurological Disorders: A Rationale for its Physio-pathological Actions

2020 ◽  
Vol 26 (21) ◽  
pp. 2475-2491 ◽  
Author(s):  
Maria Morello ◽  
Massimo Pieri ◽  
Rossella Zenobi ◽  
Alessandra Talamo ◽  
Delphine Stephan ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Vitamin D ◽  
Neurodegenerative Diseases ◽  
Neurological Disorders ◽  
Neurological Diseases ◽  
Steroid Hormone ◽  
Neuroactive Steroid ◽  
Brain Functions ◽  
Prevention And Treatment ◽  
Lateral Sclerosis

Vitamin D is a steroid hormone implicated in the regulation of neuronal integrity and many brain functions. Its influence, as a nutrient and a hormone, on the physiopathology of the most common neurodegenerative diseases is continuously emphasized by new studies. This review addresses what is currently known about the action of vitamin D on the nervous system and neurodegenerative diseases such as Multiple Sclerosis, Alzheimer’s disease, Parkinson’s disease and Amyotrophic Lateral Sclerosis. Further vitamin D research is necessary to understand how the action of this “neuroactive” steroid can help to optimize the prevention and treatment of several neurological diseases.

scholarly journals Alterations of Ultra Long-Chain Fatty Acids in Hereditary Skin Diseases—Review Article

2021 ◽  
Vol 8 ◽  
Author(s):  
Agata Zwara ◽  
Katarzyna Wertheim-Tysarowska ◽  
Adriana Mika
Keyword(s):  
Fatty Acids ◽  
Skin Diseases ◽  
Dynamic Environment ◽  
Free Form ◽  
Long Chain Fatty Acids ◽  
Inborn Errors ◽  
Clinical Consequences ◽  
Main Components ◽  
Long Chain ◽  
Chain Fatty Acids

The skin is a flexible organ that forms a barrier between the environment and the body's interior; it is involved in the immune response, in protection and regulation, and is a dynamic environment in which skin lipids play an important role in maintaining homeostasis. The different layers of the skin differ in both the composition and amount of lipids. The epidermis displays the best characteristics in this respect. The main lipids in this layer are cholesterol, fatty acids (FAs) and ceramides. FAs can occur in free form and as components of complex molecules. The most poorly characterized FAs are very long-chain fatty acids (VLCFAs) and ultra long-chain fatty acids (ULCFAs). VLCFAs and ULCFAs are among the main components of ceramides and are part of the free fatty acid (FFA) fraction. They are most abundant in the brain, liver, kidneys, and skin. VLCFAs and ULCFAs are responsible for the rigidity and impermeability of membranes, forming the mechanically and chemically strong outer layer of cell membranes. Any changes in the composition and length of the carbon chains of FAs result in a change in their melting point and therefore a change in membrane permeability. One of the factors causing a decrease in the amount of VLCFAs and ULCFAs is an improper diet. Another much more important factor is mutations in the genes which code proteins involved in the metabolism of VLCFAs and ULCFAs—regarding their elongation, their attachment to ceramides and their transformation. These mutations have their clinical consequences in the form of inborn errors in metabolism and neurodegenerative disorders, among others. Some of them are accompanied by skin symptoms such as ichthyosis and ichthyosiform erythroderma. In the following review, the structure of the skin is briefly characterized and the most important lipid components of the skin are presented. The focus is also on providing an overview of selected proteins involved in the metabolism of VLCFAs and ULCFAs in the skin.

scholarly journals A double-blind controlled trial of long chain n-3 polyunsaturated fatty acids in the treatment of multiple sclerosis.

1989 ◽  
Vol 52 (1) ◽  
pp. 18-22 ◽  
Author(s):  
D Bates ◽  
N E Cartlidge ◽  
J M French ◽  
M J Jackson ◽  
S Nightingale ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Fatty Acids ◽  
Polyunsaturated Fatty Acids ◽  
Controlled Trial ◽  
Double Blind ◽  
Long Chain

Enantioselective 2-hydroperoxylation of long-chain fatty acids in marine algae

2001 ◽  
Vol 67 (2) ◽  
pp. 328-332 ◽  
Author(s):  
Yoshihiko Akakabe ◽  
Kenji Matsui ◽  
Tadahiko Kajiwara
Keyword(s):  
Fatty Acids ◽  
Marine Algae ◽  
Long Chain Fatty Acids ◽  
Long Chain ◽  
Chain Fatty Acids

Very long chain fatty acid levels in patients diagnosed with multiple sclerosis

2009 ◽  
Vol 15 (12) ◽  
pp. 1525-1527 ◽  
Author(s):  
Alastair Wilkins ◽  
Gillian Ingram ◽  
Anny Brown ◽  
Philip Jardine ◽  
Colin G Steward ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Fatty Acids ◽  
Long Chain Fatty Acids ◽  
Serum Samples ◽  
Degree Relative ◽  
Long Chain Fatty Acid ◽  
Multiple Sclerosis Population ◽  
Long Chain ◽  
Female Carriers ◽  
Chain Fatty Acids

In clinical practice it is not uncommon for patients with adrenomyeloneuropathy or female carriers of adrenoleucodystrophy to have a presenting history and examination compatible with multiple sclerosis. This suggests that there may be an under-diagnosis of adrenoleucodystrophy and its variants in the multiple sclerosis population. We measured levels of very long chain fatty acids, which are typically elevated in the plasma of patients with adrenoleucodystrophy, in a large cohort of patients diagnosed clinically with multiple sclerosis. We tested serum samples from patients with either a first degree relative with multiple sclerosis or those with a primary progressive phenotype. No elevations in very long chain fatty acids were found in the cohort. This study suggests that the number of cases of adrenomyeloneuropathy or adrenoleucodystrophy amongst patients diagnosed clinically with multiple sclerosis is likely to be extremely low. This has important diagnostic implications.

scholarly journals Cytoprotective and Antioxidants in Peroxisomal Neurodegenerative Diseases

Proceedings ◽  
2019 ◽  
Vol 11 (1) ◽  
pp. 33 ◽  
Author(s):  
Mustapha Cherkaoui-Malki ◽  
◽  
◽  
◽  
◽  
...  
Keyword(s):  
Fatty Acids ◽  
Neurodegenerative Diseases ◽  
Neurodegenerative Disorders ◽  
Long Chain Fatty Acids ◽  
Beta Oxidation ◽  
Long Chain ◽  
Chain Fatty Acids

Several of the peroxisomal neurodegenerative disorders are the consequence of a specific deficiency of an enzyme or a transporter involved in peroxisomal beta-oxidation of very long chain fatty acids [1,2]. [...]

scholarly journals n-3 Fatty acids and mood: the devil is in the detail

2008 ◽  
Vol 99 (2) ◽  
pp. 221-223 ◽  
Author(s):  
Alex J. Richardson
Keyword(s):  
Mental Health ◽  
Fatty Acids ◽  
Immune System ◽  
American Psychiatric Association ◽  
Comprehensive Review ◽  
Chain Pufa ◽  
Prevention And Treatment ◽  
And Performance ◽  
The Devil ◽  
Long Chain

Increasing evidence suggests that a low dietary intake of the n-3 long-chain PUFA EPA and DHA may contribute not only to the risks for various physical illnesses (particularly cardiovascular and immune system disorders), but also to many disorders of mental health and performance1,2. From their recent comprehensive review of the evidence for these n-3 fatty acids in the prevention and treatment of psychiatric disorders3, the American Psychiatric Association (APA) made the following recommendations:

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