scholarly journals Limited Benefit of Marine Protein Hydrolysate on Physical Function and Strength in Older Adults: A Randomized Controlled Trial

Marine Drugs ◽  
2021 ◽  
Vol 19 (2) ◽  
pp. 62
Author(s):  
Linda Kornstad Nygård ◽  
Ingunn Mundal ◽  
Lisbeth Dahl ◽  
Jūratė Šaltytė Benth ◽  
Anne Marie Mork Rokstad
Keyword(s):  
Older Adults ◽  
Randomized Controlled Trial ◽  
Physical Function ◽  
Grip Strength ◽  
Gait Speed ◽  
Protein Intake ◽  
Protein Hydrolysate ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Marine Protein

Age-related muscle wasting can compromise functional abilities of the elderly. Protein intake stimulates muscle protein synthesis; however, ageing muscle is more resistant to stimuli. This double-blinded, randomized, controlled trial is one of the first registered studies to evaluate the effects of a supplement of marine protein hydrolysate (MPH) on measures of physical function and strength. Eighty-six older adults received nutritional supplements containing 3 g of MPH or a placebo for up to 12 months. Short Physical Performance Battery (SPPB), grip strength and gait speed were measured, and dietary intake was registered at baseline, 6 months, and 12 months. No difference was found between the intervention and control groups in mean change in SPPB (independent sample t-test, p = 0.41) or regarding time trend in SPPB, grip strength, or gait speed (linear mixed model). The participants in our study were well functioning, causing a ceiling effect in SPPB. Further, they had sufficient protein intake and were physically active. Differences in physical function between those completing the intervention and the dropouts might also have created bias in the results. We recommend that future studies of MPH be carried out on a more frail or malnourished population.

scholarly journals Effect of Individual Nutrition Therapy and Exercise Regime on Gait Speed, Physical Function, Strength and Balance, Body Composition, Energy and Protein, in Injured, Vulnerable Elderly: A Multisite Randomized Controlled Trial (INTERACTIVE)

Nutrients ◽  
2021 ◽  
Vol 13 (9) ◽  
pp. 3182
Author(s):  
Chad Yixian Han ◽  
Maria Crotty ◽  
Susie Thomas ◽  
Ian D. Cameron ◽  
Craig Whitehead ◽  
...  
Keyword(s):  
Older Adults ◽  
Randomized Controlled Trial ◽  
Body Composition ◽  
Gait Speed ◽  
Protein Intake ◽  
Controlled Trial ◽  
Nutrition Therapy ◽  
Nutrition Intervention ◽  
Randomized Controlled ◽  
Secondary Outcomes

It is imperative that the surgical treatment of hip fractures is followed up with rehabilitation to enhance recovery and quality of life. This randomized controlled trial aimed to determine if an individualised, combined exercise–nutrition intervention significantly improved health outcomes in older adults, after proximal femoral fracture. We commenced the community extended therapy while in hospital, within two weeks post-surgery. The primary outcome was gait speed and secondary outcomes included physical function, strength and balance, body composition, energy and protein intake. Eighty-six and 89 participants were randomized into six months individualised exercise and nutrition intervention and attention-control groups, respectively. There were no statistically significant differences in gait speed between the groups at six and 12 months. There were no major differences between groups with respect to the secondary outcomes, except estimated energy and protein intake. This may be explained by the sample size achieved. Participants in the intervention group had greater increment in energy (235 kcal; 95% CI, 95 to 375; p = 0.01) and protein intake (9.1 g; 95% CI, 1.5 to 16.8; p = 0.02), compared with those in the control group at six months but not significant at 12 months. This study has demonstrated that providing early, combined exercise and nutrition therapy can improve dietary energy and protein intake in older adults with hip fractures.

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