scholarly journals Mixtures of Lipophilic Phycotoxins: Exposure Data and Toxicological Assessment

Marine Drugs ◽  
2018 ◽  
Vol 16 (2) ◽  
pp. 46 ◽  
Author(s):  
Jimmy Alarcan ◽  
Ronel Biré ◽  
Ludovic Le Hégarat ◽  
Valérie Fessard
2020 ◽  
pp. 31-32
Author(s):  
Mikhail A. Levchenko ◽  
◽  
Natalia A. Sennikova ◽  

Toxicological assessment is a mandatory research step in the development of new insecticidal drugs. At the All-Russian Research Institute of Veterinary Entomology and Arachnology, a prototype of the insecticidal bait Mukhnet IF was obtained with an active ingredient content of 0.06% ivermectin and 0.015% fipronil, which showed a highly effective effect against houseflies. This work presents the results of the study of acute oral toxicity of the above agent. For this, male white mice with a live weight of 16-26 g were selected. They were kept on a starvation diet for one day in individual houses with water. The drug was given in mg/kg body weight the next day. A total of 33 doses have been tested, ranging from 100 mg/kg to 40,000 mg/kg. The animals were observed for 14 days. According to the research results, it was revealed that at doses up to 20,000 mg/kg there were no signs of intoxication, but when tested at 25,000 mg/kg in some mice, these signs were noted, and at 30,000, 35,000 and 40,000 mg/kg deaths were recorded 20±10, 45±30 and 60±20%, respectively. It was not possible to test the drug over the last above dose due to incomplete eaten by mice. According to the degree of danger for warm-blooded animals, the drug belongs to the 4th class of low-hazard drugs (average lethal dose of 5000 mg/kg or more) in accordance with the classification of GOST 12.1.007-76. When analyzing the literature data on the toxicological characteristics of preparations containing ivermectin and chlorfenapyr, it was revealed that the insecticidal agent in its acute toxicity for warm-blooded animals is comparable to known analogues.


2019 ◽  
Vol 3 (3) ◽  
pp. 64-70 ◽  
Author(s):  
Rashydah Ahmed ◽  
◽  
Hadiza Nuhu ◽  
Hajara Ibrahim ◽  
Aliyu Nuhu ◽  
...  

2019 ◽  
Vol 21 (2) ◽  
pp. 122-135
Author(s):  
Caroline Barros de Sales ◽  
Samara Sayonara Cândida da Silva ◽  
Lutiane Queiroz de Almeida

O presente trabalho tem como objetivo caracterizar o risco nas comunidades Mazagão 1 e José da Silva Sobral, a partir de indicadores sociais de vulnerabilidade e ambientais de perigo para movimentos de massa. Para isso, buscou-se inicialmente o levantamento bibliográfico, respaldando-se em autores que trabalham com as temáticas de riscos e vulnerabilidade, e foram realizadas atividades de campo, as quais possibilitaram a aplicação dos questionários de vulnerabilidade social e das fichas de exposição a movimentos de massa, além de permitir a realização de registros fotográficos. A partir da sistematização dos dados de vulnerabilidade social e de exposição, permitiu-se estabelecer as características mais presentes nas comunidades, indicando os elementos mais críticos, os quais colaboram para que haja risco de movimentos de massa, apontando então para a necessidade de pesquisas que venham a estudar profundamente a situação, podendo vir a propor medidas mitigadoras diretamente aplicáveis à área de risco.Palavras-chave: Vulnerabilidade; Perigo; Desastre. ABSTRACTThe present work aims to characterize the risk in the communities Mazagão 1 and José da Silva Sobral, considering social indicators of vulnerability and environmental indicators of danger to mass movements. In order to do this, a bibliographical survey was sought, supported by authors working on the themes of risk and vulnerability, and field activities were carried out, which made possible the application of the social vulnerability questionnaires and the exposure sheets to mass movements, besides allowing the realization of photographic records. Systematizing social vulnerability and exposure data, the most present characteristics in the communities were established, indicating the most critical elements, which contribute to the risk of mass movements, pointing to the need for research that will deeply study the situation, and may propose mitigating measures directly applicable to the area of risk.Keywords: Vulnerability; Danger; Disaster. RESUMENEste trabajo tiene como objetivo caracterizar el riesgo en las comunidades Mazagão 1 y José da Silva Sobral, con base en indicadores sociales de vulnerabilidad y peligro ambiental para los movimientos de masas. Para ello, se buscó inicialmente la investigación bibliográfica, apoyada por autores que trabajan con los temas de riesgos y vulnerabilidad, y se llevaron a cabo actividades de campo, que permitieron la aplicación de cuestionarios de vulnerabilidad social y hojas de exposición al movimiento, además de permitir la realización de registros fotográficos. A partir de la sistematización de datos sobre vulnerabilidad social y exposición, fue posible establecer las características más comunes en las comunidades, indicando los elementos más críticos, que contribuyen al riesgo de movimientos masivos, señalando la necesidad de una investigación que Estudie la situación en profundidad y proponga medidas de mitigación directamente aplicables al área de riesgo.Palabras Claves: Vulnerabilidad; Peligro; Desastre.


Author(s):  
A. A. Maslennikov ◽  
S. A. Demidova ◽  
A. V. Ryabova

Water containing polyvinyl nitrate was experimentally assessed on the basis of organoleptic, general sanitary and toxicological indicators of harmfulness. It was established that that the compound did not change water organoleptic properties but produced a negative impact on viability of saprophytic microflora , nitrification processes and biochemical oxygen demand. Besides, in tests on animals. the substance caused acute, sub-acute and chronic toxicity. Based on those signs of harmfulness, threshold levels of exposure were established. Data obtained were taken into account for substantiation of MAC (Maximum allowable concentration) of polyvinyl nitrate in water bodies.


2018 ◽  
Author(s):  
Phillip Monin ◽  
Matthew G. Pritsker ◽  
Stathis Tompaidis
Keyword(s):  

2020 ◽  
Author(s):  
Katharine Horzmann ◽  
◽  
Chloe de Perre ◽  
Linda S. Lee ◽  
Andrew J. Whelton ◽  
...  

2011 ◽  
Vol 45 (3) ◽  
pp. 1394-1402 ◽  
Author(s):  
Alam G. Trovó ◽  
Raquel F. Pupo Nogueira ◽  
Ana Agüera ◽  
Amadeo R. Fernandez-Alba ◽  
Sixto Malato

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