scholarly journals Global Dynamics of an SEIR Model with the Age of Infection and Vaccination

Mathematics ◽  
2021 ◽  
Vol 9 (18) ◽  
pp. 2195
Author(s):  
Huaixing Li ◽  
Jiaoyan Wang
Keyword(s):  
Local Stability ◽  
Reproduction Number ◽  
Steady States ◽  
Global Dynamics ◽  
Seir Model ◽  
Age Of Infection ◽  
The Stability ◽  
Theoretical Results ◽  
Disease Free ◽  
The Basic Reproduction Number

This paper is concerned with the stability of a SEIR (susceptible-exposed-infectious-recovered) model with the age of infection and vaccination. Firstly, we prove the positivity, boundedness, and asymptotic smoothness of the solutions. Next, the existence and local stability of disease-free and endemic steady states are shown. The basic reproduction number R0 is introduced. Furthermore, the global stability of the disease-free and endemic steady states is derived. Numerical simulations are shown to illustrate our theoretical results.

scholarly journals Global dynamics of a delayed epidemic model with latency and relapse

2013 ◽  
Vol 18 (2) ◽  
pp. 250-263 ◽  
Author(s):  
Rui Xu
Keyword(s):  
Basic Reproduction Number ◽  
Local Stability ◽  
Reproduction Number ◽  
Endemic Equilibrium ◽  
Global Dynamics ◽  
Lyapunov Functionals ◽  
Asymptotically Stable ◽  
Globally Asymptotically Stable ◽  
Disease Free ◽  
The Basic Reproduction Number

A mathematical model describing the transmission dynamics of an infectious disease with an exposed (latent) period, relapse and a saturation incidence rate is investigated. By analyzing the corresponding characteristic equations, the local stability of a disease-free equilibrium and an endemic equilibrium is established. By using suitable Lyapunov functionals and LaSalle’s invariance principle, it is proven that if the basic reproduction number is less than unity, the diseasefree equilibrium is globally asymptotically stable and therefore the disease fades out; and if the basic reproduction number is greater than unity, the endemic equilibrium is globally asymptotically stable and the disease becomes endemic.

scholarly journals Dynamical Analysis of an SEIRS Model With Incomplete Recovery and Relapse on Networks and Its Optimal Vaccination Control

2021 ◽  
Author(s):  
Lei Zhang ◽  
Maoxing Liu ◽  
Qiang Hou ◽  
Boli Xie
Keyword(s):  
Control Strategy ◽  
Reproduction Number ◽  
Dynamical Analysis ◽  
Global Dynamics ◽  
Asymptotically Stable ◽  
Globally Asymptotically Stable ◽  
Seirs Epidemic Model ◽  
Theoretical Results ◽  
Disease Free ◽  
The Basic Reproduction Number

Abstract For some infectious diseases, such as herpes and tuberculosis, there is incomplete recovery and relapse. These phenomena make them difficult to control. In consequence of this status, an SEIRS epidemic model with incomplete recovery and relapse on networks is established and the global dynamics is studied. The results show that when the basic reproduction number R 0 <=1 the disease-free equilibrium is globally asymptotically stable; when R 0 > 1, the endemic equilibrium is globally asymptotically stable. In addition, in consideration of vaccination control strategy, an SVEIRS model is introduced and the optimal control is solved. At last, the theoretical results are illustrated with numerical simulations.

scholarly journals Dynamics of the rumor-spreading model with hesitation mechanism in heterogenous networks and bilingual environment

2020 ◽  
Vol 2020 (1) ◽  
Author(s):  
Shuai Yang ◽  
Haijun Jiang ◽  
Cheng Hu ◽  
Juan Yu ◽  
Jiarong Li
Keyword(s):  
Lyapunov Method ◽  
Reproduction Number ◽  
Model Parameters ◽  
Rumor Spreading ◽  
Spreading Model ◽  
Reductio Ad Absurdum ◽  
The Stability ◽  
The Impact ◽  
Theoretical Results ◽  
The Basic Reproduction Number

Abstract In this paper, a novel rumor-spreading model is proposed under bilingual environment and heterogenous networks, which considers that exposures may be converted to spreaders or stiflers at a set rate. Firstly, the nonnegativity and boundedness of the solution for rumor-spreading model are proved by reductio ad absurdum. Secondly, both the basic reproduction number and the stability of the rumor-free equilibrium are systematically discussed. Whereafter, the global stability of rumor-prevailing equilibrium is explored by utilizing Lyapunov method and LaSalle’s invariance principle. Finally, the sensitivity analysis and the numerical simulation are respectively presented to analyze the impact of model parameters and illustrate the validity of theoretical results.

scholarly journals Threshold Dynamics of a Huanglongbing Model with Logistic Growth in Periodic Environments

2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Jianping Wang ◽  
Shujing Gao ◽  
Yueli Luo ◽  
Dehui Xie
Keyword(s):  
Basic Reproduction Number ◽  
Reproduction Number ◽  
Logistic Growth ◽  
Threshold Dynamics ◽  
Global Dynamics ◽  
Globally Asymptotically Stable ◽  
Linear Integral ◽  
The Impact ◽  
Disease Free ◽  
The Basic Reproduction Number

We analyze the impact of seasonal activity of psyllid on the dynamics of Huanglongbing (HLB) infection. A new model about HLB transmission with Logistic growth in psyllid insect vectors and periodic coefficients has been investigated. It is shown that the global dynamics are determined by the basic reproduction numberR0which is defined through the spectral radius of a linear integral operator. IfR0< 1, then the disease-free periodic solution is globally asymptotically stable and ifR0> 1, then the disease persists. Numerical values of parameters of the model are evaluated taken from the literatures. Furthermore, numerical simulations support our analytical conclusions and the sensitive analysis on the basic reproduction number to the changes of average and amplitude values of the recruitment function of citrus are shown. Finally, some useful comments on controlling the transmission of HLB are given.

scholarly journals Simple MSEIR Model for Measles Transmission

2019 ◽  
pp. 1-11
Author(s):  
Mojeeb Al-Rahman EL-Nor Osman ◽  
Appiagyei Ebenezer ◽  
Isaac Kwasi Adu
Keyword(s):  
Mathematical Model ◽  
Basic Reproduction Number ◽  
Recovery Rate ◽  
Birth Rate ◽  
Reproduction Number ◽  
Progression Rate ◽  
Asymptotically Stable ◽  
The Stability ◽  
Disease Free ◽  
The Basic Reproduction Number

In this paper, an Immunity-Susceptible-Exposed-Infectious-Recovery (MSEIR) mathematical model was used to study the dynamics of measles transmission. We discussed that there exist a disease-free and an endemic equilibria. We also discussed the stability of both disease-free and endemic equilibria.  The basic reproduction number  is obtained. If , then the measles will spread and persist in the population. If , then the disease will die out.  The disease was locally asymptotically stable if  and unstable if  . ALSO, WE PROVED THE GLOBAL STABILITY FOR THE DISEASE-FREE EQUILIBRIUM USING LASSALLE'S INVARIANCE PRINCIPLE OF Lyaponuv function. Furthermore, the endemic equilibrium was locally asymptotically stable if , under certain conditions. Numerical simulations were conducted to confirm our analytic results. Our findings were that, increasing the birth rate of humans, decreasing the progression rate, increasing the recovery rate and reducing the infectious rate can be useful in controlling and combating the measles.

scholarly journals Global dynamics of a Huanglongbing model with a periodic latent period

2021 ◽  
Vol 0 (0) ◽  
pp. 0
Author(s):  
Yan Hong ◽  
Xiuxiang Liu ◽  
Xiao Yu
Keyword(s):  
Reproduction Number ◽  
Threshold Value ◽  
Transmission Model ◽  
Threshold Dynamics ◽  
Global Dynamics ◽  
Temperature Dependent ◽  
Candidatus Liberibacter ◽  
Effects Of Temperature ◽  
Disease Free ◽  
The Basic Reproduction Number

<p style='text-indent:20px;'>Huanglongbing (HLB) is a disease of citrus that caused by phloem-restricted bacteria of the Candidatus Liberibacter group. In this paper, we present a HLB transmission model to investigate the effects of temperature-dependent latent periods and seasonality on the spread of HLB. We first establish disease free dynamics in terms of a threshold value <inline-formula><tex-math id="M1">\begin{document}$ R^p_0 $\end{document}</tex-math></inline-formula>, and then introduce the basic reproduction number <inline-formula><tex-math id="M2">\begin{document}$ \mathcal{R}_0 $\end{document}</tex-math></inline-formula> and show the threshold dynamics of HLB with respect to <inline-formula><tex-math id="M3">\begin{document}$ R^p $\end{document}</tex-math></inline-formula> and <inline-formula><tex-math id="M4">\begin{document}$ \mathcal{R}_0 $\end{document}</tex-math></inline-formula>. Numerical simulations are further provided to illustrate our analytic results.</p>

scholarly journals Analysis of the Mathematical Model for the Spread of Pine Wilt Disease

2013 ◽  
Vol 2013 ◽  
pp. 1-10 ◽  
Author(s):  
Xiangyun Shi ◽  
Guohua Song
Keyword(s):  
Basic Reproduction Number ◽  
Reproduction Number ◽  
Pine Wilt Disease ◽  
Wilt Disease ◽  
Endemic Equilibrium ◽  
Feasible Region ◽  
Global Dynamics ◽  
Pine Wilt ◽  
Theoretical Results ◽  
The Basic Reproduction Number

This paper formulates and analyzes a pine wilt disease model. Mathematical analyses of the model with regard to invariance of nonnegativity, boundedness of the solutions, existence of nonnegative equilibria, permanence, and global stability are presented. It is proved that the global dynamics are determined by the basic reproduction numberℛ0and the other valueℛcwhich is larger thanℛ0. Ifℛ0andℛcare both less than one, the disease-free equilibrium is asymptotically stable and the pine wilt disease always dies out. If one is between the two values, though the pine wilt disease could occur, the outbreak will stop. If the basic reproduction number is greater than one, a unique endemic equilibrium exists and is globally stable in the interior of the feasible region, and the disease persists at the endemic equilibrium state if it initially exists. Numerical simulations are carried out to illustrate the theoretical results, and some disease control measures are especially presented by these theoretical results.

scholarly journals Global Dynamics of an SIQR Model with Vaccination and Elimination Hybrid Strategies

Mathematics ◽  
2018 ◽  
Vol 6 (12) ◽  
pp. 328 ◽  
Author(s):  
Yanli Ma ◽  
Jia-Bao Liu ◽  
Haixia Li
Keyword(s):  
Lyapunov Function ◽  
Basic Reproduction Number ◽  
Epidemic Model ◽  
Reproduction Number ◽  
Endemic Equilibrium ◽  
Global Dynamics ◽  
Asymptotically Stable ◽  
Globally Asymptotically Stable ◽  
Disease Free ◽  
The Basic Reproduction Number

In this paper, an SIQR (Susceptible, Infected, Quarantined, Recovered) epidemic model with vaccination, elimination, and quarantine hybrid strategies is proposed, and the dynamics of this model are analyzed by both theoretical and numerical means. Firstly, the basic reproduction number R 0 , which determines whether the disease is extinct or not, is derived. Secondly, by LaSalles invariance principle, it is proved that the disease-free equilibrium is globally asymptotically stable when R 0 < 1 , and the disease dies out. By Routh-Hurwitz criterion theory, we also prove that the disease-free equilibrium is unstable and the unique endemic equilibrium is locally asymptotically stable when R 0 > 1 . Thirdly, by constructing a suitable Lyapunov function, we obtain that the unique endemic equilibrium is globally asymptotically stable and the disease persists at this endemic equilibrium if it initially exists when R 0 > 1 . Finally, some numerical simulations are presented to illustrate the analysis results.

scholarly journals Global Dynamics of Infectious Disease with Arbitrary Distributed Infectious Period on Complex Networks

2014 ◽  
Vol 2014 ◽  
pp. 1-9
Author(s):  
Xiaoguang Zhang ◽  
Rui Song ◽  
Gui-Quan Sun ◽  
Zhen Jin
Keyword(s):  
Complex Networks ◽  
Reproduction Number ◽  
Epidemic Models ◽  
Infectious Period ◽  
Global Dynamics ◽  
Globally Asymptotically Stable ◽  
Sis Epidemic Model ◽  
Different Types ◽  
Theoretical Results ◽  
Disease Free

Most of the current epidemic models assume that the infectious period follows an exponential distribution. However, due to individual heterogeneity and epidemic diversity, these models fail to describe the distribution of infectious periods precisely. We establish a SIS epidemic model with multistaged progression of infectious periods on complex networks, which can be used to characterize arbitrary distributions of infectious periods of the individuals. By using mathematical analysis, the basic reproduction numberR0for the model is derived. We verify that theR0depends on the average distributions of infection periods for different types of infective individuals, which extend the general theory obtained from the single infectious period epidemic models. It is proved that ifR0<1, then the disease-free equilibrium is globally asymptotically stable; otherwise the unique endemic equilibrium exists such that it is globally asymptotically attractive. Finally numerical simulations hold for the validity of our theoretical results is given.

THE DYNAMICS OF A DISCRETE SEIT MODEL WITH AGE AND INFECTION AGE STRUCTURES

2012 ◽  
Vol 05 (03) ◽  
pp. 1260004 ◽  
Author(s):  
HUI CAO ◽  
YANNI XIAO ◽  
YICANG ZHOU
Keyword(s):  
Reproduction Number ◽  
Endemic Equilibrium ◽  
Disease Spread ◽  
Threshold Parameter ◽  
Infection Age ◽  
The Stability ◽  
Globally Stable ◽  
Disease Free ◽  
The Basic Reproduction Number ◽  
Age Structures

Age and infection age have significant influence on the transmission of infectious diseases, such as HIV/AIDS and TB. A discrete SEIT model with age and infection age structures is formulated to investigate the dynamics of the disease spread. The basic reproduction number R0 is defined and used as the threshold parameter to characterize the disease extinction or persistence. It is shown that the disease-free equilibrium is globally stable if R0 < 1, and it is unstable if R0 > 1. When R0 > 1, there exists an endemic equilibrium, and the disease is uniformly persistent. The stability of the endemic equilibrium is investigated numerically.

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