scholarly journals Pentamethinium Salts Nanocomposite for Electrochemical Detection of Heparin

Materials ◽  
2021 ◽  
Vol 14 (18) ◽  
pp. 5357
Author(s):  
Tatiana V. Shishkanova ◽  
Tomáš Bříza ◽  
Pavel Řezanka ◽  
Zdeněk Kejík ◽  
Milan Jakubek

This study presents a simple route to heparin detection and develops a voltammetric approach using supramolecular principles and nanomaterials. Nanocomposites, including gold nanoparticles (AuNPs) and γ-substituted pentamethinium salts (PMS) deposited on a glass carbon (GC) electrode surface (GC/AuNPs/PMS) and covered by a plasticized poly(vinyl chloride) (PVC) membrane, are proposed for heparin detection. The conductivity of the nonconducting PVC-plasticized membrane is guaranteed by AuNPs, and the selectivity is provided by the interaction between γ-substituted PMS and anionic analytes. In order to extend the linear range, it is necessary to apply a solvent compatible with PVC-plasticized membrane, namely tetrahydrofuran. The proposed voltammetric sensor showed a concentration dependence from 1.72 up to 45.02 IU mL−1 heparin and was used for heparin detection in saline and biological samples with recovery of 95.1–100.9%.

2021 ◽  
Author(s):  
Benadict Joseph Xavier ◽  
Umesh N ◽  
Sea-Fue Wang ◽  
Antolin Jesilaa Jesu Amalraj

The quantification of the neurotransmitter dopamine in human biological samples has gained more importance. A good antifouling, and highly selective electrode material is still in high demand. So, to resolve...


2020 ◽  
Vol 40 (10) ◽  
pp. 842-847
Author(s):  
Shankar Suman ◽  
Ram Singh

AbstractA new poly (vinyl chloride) (PVC) membrane electrode using 2-benzoylpyridine semicarbazone as membrane carrier with dioctylphthalate as plasticizer and sodium tetraphenylborate (NaTBP) as anion excluder has been fabricated and investigated as Zn(II)-selective electrode. Best potential response is observed for the composition PVC 30%, plasticizer 58%, NaTBP 8% and ionophore 4% (w/w). The sensor showed a linear stable response over a concentration range of 1.0 × 10−2–4.56 × 10−6 M with a detection limit of 2.28 × 10−6 M and a response time <10 s. The electrode can be used for at least six months without any divergence in potential.


2021 ◽  
Author(s):  
Hexiang Li ◽  
Fawei Zhu ◽  
Jun Xiang ◽  
Fangbin Wang ◽  
Qi Liu ◽  
...  

We herein report a facile and scalable strategy for fabrication of the metal organic frameworks (MOFs) based composite by in-situ growing ZIF-8 on the gold nanoparticles (AuNPs) loaded magnetic carbon...


RSC Advances ◽  
2017 ◽  
Vol 7 (41) ◽  
pp. 25702-25709 ◽  
Author(s):  
R. Karthik ◽  
Mani Govindasamy ◽  
Shen-Ming Chen ◽  
Tse-Wei Chen ◽  
J. Vinoth kumar ◽  
...  

An electrochemical sensor based on graphene oxide modified glassy carbon electrode for the determination of anti-cancer drug flutamide.


RSC Advances ◽  
2015 ◽  
Vol 5 (70) ◽  
pp. 56583-56589 ◽  
Author(s):  
Yulan Wang ◽  
Dan Wu ◽  
Yong Zhang ◽  
Xiang Ren ◽  
Yaoguang Wang ◽  
...  

In this work, a novel and ultrasensitive label-free electrochemical immunosensor was developed for the quantitative detection of alpha fetoprotein (AFP).


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