scholarly journals Accelerated Bone Induction of Adult Rat Compact Bone Plate Scratched by Ultrasonic Scaler Using Acidic Electrolyzed Water

Materials ◽  
2021 ◽  
Vol 14 (12) ◽  
pp. 3347
Author(s):  
Mamata Shakya ◽  
Masaru Murata ◽  
Kenji Yokozeki ◽  
Toshiyuki Akazawa ◽  
Hiroki Nagayasu ◽  
...  
Keyword(s):  
Ultrasonic Treatment ◽  
Compact Bone ◽  
Parietal Bone ◽  
New Combination ◽  
Graft Material ◽  
Skull Bone ◽  
Vascular Perfusion ◽  
Electrolyzed Water ◽  
Combination Technique ◽  
Ultrasonic Scaler

Fresh compact bone, the candidate graft material for bone regeneration, is usually grafted for horizontal bone augmentation. However, the dense calcified structure inhibits the release of growth factors and limits cellular and vascular perfusion. We aimed to create mechano-chemically altered dense skull bone by ultrasonic treatment, along with partial demineralization using commercially available acidic electrolyzed water (AEW). The parietal skull bone of an 11-month-old Wistar rat was exposed and continuously treated with a piezoelectric ultrasonic scaler tip for 1 min, using AEW (pH 2.3) or distilled water (DW, pH 5.6) as irrigants. Treated parietal bone was removed, cut into plates (5 × 5 × 1 mm3), grafted into the back subcutaneous tissues of syngeneic rats, and explanted at 1, 2, and 3 weeks. AEW bone showed an irregular surface, deep nano-microcracks, and decalcified areas. SEM-EDS revealed small amounts of residual calcium content in the AEW bone (0.03%) compared to the DW bone (0.86%). In the animal assay, the AEW bone induced bone at 2 weeks. Histomorphometric analysis showed that the area of new bone in the AEW bone at 2 and 3 weeks was significantly larger. This new combination technique of AEW-demineralization with ultrasonic treatment will improve the surface area and three-dimensional (3D) architecture of dense bone and accelerate new bone synthesis.

scholarly journals MICROCRACKS DESIGN AND BONE INDUCTION OF SKULL BONE MODIFIED BY ULTRASONIC TREATMENT USING ACIDIC ELECTROLYZED WATER

2017 ◽  
Vol 33 (0) ◽  
pp. 1-6
Author(s):  
MAMATA SHAKYA ◽  
MASARU MURATA ◽  
NAOTO OKUBO ◽  
HIROKI NAGAYASU ◽  
TOSHIYUKI AKAZAWA
Keyword(s):  
Ultrasonic Treatment ◽  
Bone Induction ◽  
Skull Bone ◽  
Electrolyzed Water

A Non-Monotone Line Search Combination Technique for Unconstrained Optimization

2014 ◽  
Vol 8 (1) ◽  
pp. 218-221 ◽  
Author(s):  
Ping Hu ◽  
Zong-yao Wang
Keyword(s):  
Global Convergence ◽  
Unconstrained Optimization ◽  
Numerical Experiments ◽  
Line Search ◽  
Optimization Problems ◽  
Search Algorithm ◽  
New Combination ◽  
Combination Rule ◽  
Combination Technique ◽  
Unconstrained Optimization Problems

We propose a non-monotone line search combination rule for unconstrained optimization problems, the corresponding non-monotone search algorithm is established and its global convergence can be proved. Finally, we use some numerical experiments to illustrate the new combination of non-monotone search algorithm’s effectiveness.

scholarly journals Maxillary Sinus Augmentation with Decellularized Bovine Compact Particles: A Radiological, Clinical, and Histologic Report of 4 Cases

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Antonio Scarano
Keyword(s):  
Postoperative Period ◽  
Compact Bone ◽  
Automated System ◽  
Graft Material ◽  
Sinus Augmentation ◽  
Endosseous Implants ◽  
Implant Placement ◽  
Posterior Maxilla ◽  
The Mean ◽  
Vertical Height

Background. One of the most problematic regions for endosseous implants is the posterior maxilla, not only having poor bone density, but also lacking adequate vertical height as a result of sinus pneumatization. The purpose of the present study was a radiologic, histological, and histomorphometrical evaluation, in humans, of specimens retrieved from sinuses augmented with decellularized bovine compact particles, after a healing period of 6 months. Methods. Four patients, with atrophic resorbed maxillas, underwent a sinus lift augmentation with decellularized bovine compact bone from bovine femur. The size of the particles used was 0.25–1 mm. A total of four grafts and 5 biopsies were retrieved and processed to obtain thin ground sections with the Precise 1 Automated System. Results. The mean volume after graft elevation calculated for each of the 4 patients was 2106 mm3 in the immediate postoperative period (5–7 days), ranging from 1408.8 to 2946.4 mm3. In the late postoperative period (6 months) it was 2053 mm3, ranging from 1339.9 to 2808.9 mm3. Histomorphometry showed that newly formed bone was 36±1.6% and marrow spaces were 34±1.6%, while the residual graft material was 35±1.4%. Conclusion. In conclusion, based on the outcome of the present study, Re-Bone® can be used with success in sinus augmentation procedures and 6 months are considered an adequate time for maturation before implant placement.

Interface Function Design and Bone-Regenerative Engineering of Biomimetic Biomaterials by Supersonic Treatment Using Electrolyzed Water

2014 ◽  
Vol 631 ◽  
pp. 241-246 ◽  
Author(s):  
Toshiyuki Akazawa ◽  
Masaru Murata ◽  
Y. Minamida ◽  
Md. Arafat Kabir ◽  
M. Ito ◽  
...  
Keyword(s):  
Interface Design ◽  
Bone Growth ◽  
Porous Ceramics ◽  
Parietal Bone ◽  
Spherical Particles ◽  
Human Teeth ◽  
Electrolyzed Water ◽  
Water Ph ◽  
Interface Function ◽  
Bone Growth Factor

As interface design of autotransportation materials and bioactive ceramics by supersonic treatment, human teeth-originated granules and commercial hydroxyapatite (HAp) were partially dissolved in different acid solutions, such as electrolyzed water and HNO3aqueous solution to control bio-absorption, adsorption-release of bone growth factor and anti-bacterial characteristics. Human teeth were pulverized with cooling, dissolved in strongly acidic electrolyzed water (pH 2.6-3.1) or 2.0% HNO3solution to obtain demineralized dentin matrix granules. For supersonic or stirring demineralization in the acidic electrolyzed water, dissolution efficiencies (DE) were 3-12% and dentinal tubules with 1-2μm were found, while for supersonic demineralization in the HNO3solution, DE was attained to the highest value of 86%. When HAp was dissolved with stirring in the acidic electrolyzed water, DE of porous ceramics was lower than that of spherical particles due to smaller specific surface area and good crystallinity. For supersonic dissolution of porous ceramics in the acidic electrolyzed water, DE was 30% and extension of grain boundary and micro-crack were observed. Concerning supersonic irradiation of the electolyzed water to parietal bone in rats by using ultrasonic scaler, enlargement and propagation of micro-crack were recognized on the hard tissues.

scholarly journals Effect of Bio-Oss® Collagen and Collagen Matrix on Bone Formation

2010 ◽  
Vol 4 (1) ◽  
pp. 71-76 ◽  
Author(s):  
R.W.K Wong ◽  
A.B.M Rabie
Keyword(s):  
Bone Formation ◽  
Collagen Matrix ◽  
Negative Control Group ◽  
Positive Control ◽  
Negative Control ◽  
Parietal Bone ◽  
Control Group ◽  
Graft Material ◽  
New Bone Formation

Objective: to compare the amount of new bone produced by Bio-Oss® Collagen to that produced by collagen matrix in vivo. Method: eighteen bone defects, 5mm by 10mm were created in the parietal bone of 9 New Zealand White rabbits. 6 defects were grafted with Bio-Oss® Collagen. 6 defects were grafted with collagen matrix alone (positive control) and 6 were left empty (negative control). Animals were killed on day 14 and the defects were dissected and prepared for histological assessment. Quantitative analysis of new bone formation was made on 100 sections (50 sections for each group) using image analysis. Results: A total of 339% more new bone was present in defects grafted with Bio-Oss® Collagen than those grafted with collagen matrix (positive control). No bone was formed in the negative control group. Conclusion: Bio-Oss® Collagen has the effect of stimulating new bone formation locally compared with collagen matrix in vivo. Bio-Oss® Collagen may be utilized as a bone graft material.

scholarly journals Radiological Mapping Of Nepalese Calvaria.

2013 ◽  
Vol 2 (1) ◽  
pp. 31-35
Author(s):  
Manoj Bhattarai
Keyword(s):  
Compact Bone ◽  
Cross Sectional Study ◽  
Parietal Bone ◽  
Frontal Bone ◽  
Cranial Vault ◽  
Cranial Cavity ◽  
Cross Sectional ◽  
Medical College ◽  
The Mean ◽  
Outer Table

Introduction Skull has cranial vault and base. The cranial vault is called as calvarium which roofs the cranial cavity (brain box).Cranial vault consists of frontal, parietal and occipital bones. Total thickness of calvarial bones includes outer table, diploe and inner table. Diploe is made up of spongy bone whereas outer and inner table made up of compact bone. Objective To measure the thickness of Nepalese calvarial bones i.e. Frontal, Parietal and Occipital. Methods It is a hospital base cross-sectional study. CT records of one hundred and fifty adult people were studied. Nine various points on frontal bone, seven on parietal and six on occipital were located and their thickness were measured bilaterally with help of CT scan. Results The present study showed that Mean thickness+_SD of frontal bone were 6.1+_1.8mm; parietal 4.6+_2.2 and occipital 9.5+_3.4. The study also showed that frontal bone had 2.4+_0.8 mm thick outer table; 1.4+_0.6mm inner table and 3.5+_1.3mm diploe. Similarly parietal bone had 1.9+_0.6 mm thick outer table; 1.1+_0.4mm inner table and 0.8+_0.5mm diploe. The occipital bone had 3.5+_1.5 mm thick outer table; 2.2+_0.8mm inner table and 4.3+_1.8mm diploe. Similarly this present study also calculated the mean thickness+_SD of outer table in the calvarium as 2.7+_1.3mm and that of inner table 1.5+_0.9 mm. Thus it concluded that outer table was thicker than inner table. Journal of Nobel Medical College Vol. 2, No.1 Issue 3 Nov.-April 2013 Page 31-35 DOI: http://dx.doi.org/10.3126/jonmc.v2i1.7670

scholarly journals Computed tomographic scanning measurement of skull bone thickness: a single center study

2018 ◽  
Vol 6 (3) ◽  
pp. 913
Author(s):  
Fowzia Farzana ◽  
Bashir A. Shah ◽  
Shaheen Shadad ◽  
Peerzada Zia ul Haq ◽  
Arif Sarmast ◽  
...  
Keyword(s):  
Ct Scan ◽  
Computerized Tomography ◽  
Parietal Bone ◽  
Radiology Department ◽  
Human Beings ◽  
Skull Bone ◽  
Computed Tomographic ◽  
Study Population ◽  
The Mean ◽  
The Right

Background: Computerized tomography scan (CT scan) can be useful for the measuring the calvarial thickness in human beings. This could help in identifying the racial and the gender variations in calvarial thickness in a population. The data obtained about calvarial thickness study in human population may be useful for researchers, anatomists, anthropologists, surgeons and manufacturers of surgical screws.Methods: This was an observational study carried out on 104 subjects, with a normal computerized tomography CT scan of the head. Any subject with a skull fractures or an underlying intracranial lesion were excluded from study. A total of 52 males and 52 females who presented in the radiology department for CT head were studied in a consecutive manner. The thickness of skull bone was measured on console (Somatom, Siemens 16 slice).Results: Our study population consisted of 52 male and 52 female subjects. The mean age for males was 48.03 (Range 18-70) years and while as the mean age of females was 47.37 (Range 18-73) years. We did not find any difference in the thickness of the frontal bone at upper third, middle third and lower third between the two sexes. However, the posterior third parietal bone, the anterior and middle third occipital bone was significantly thicker in females when compared to males.Conclusions: Our study suggests that the anterior third of the parietal bone has a more calvarial thickness on the right side than on the left side in both males and females. However, the female calvarium has a significantly thicker calvarium at the posterior third parietal; anterior and middle third occipital bones when compared to male counterparts showing a sexual dimorphism in our study population.

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