scholarly journals Structural and Material Determinants Influencing the Behavior of Porous Ti and Its Alloys Made by Additive Manufacturing Techniques for Biomedical Applications

Materials ◽  
2021 ◽  
Vol 14 (4) ◽  
pp. 712
Author(s):  
Magda Dziaduszewska ◽  
Andrzej Zieliński
Keyword(s):  
Additive Manufacturing ◽  
Bone Structure ◽  
Bone Substitutes ◽  
Biological Properties ◽  
Pore Shape ◽  
Porous Structures ◽  
Porous Ti ◽  
Geometrical Features ◽  
Manufacturing Techniques ◽  
Segmental Bone

One of the biggest challenges in tissue engineering is the manufacturing of porous structures that are customized in size and shape and that mimic natural bone structure. Additive manufacturing is known as a sufficient method to produce 3D porous structures used as bone substitutes in large segmental bone defects. The literature indicates that the mechanical and biological properties of scaffolds highly depend on geometrical features of structure (pore size, pore shape, porosity), surface morphology, and chemistry. The objective of this review is to present the latest advances and trends in the development of titanium scaffolds concerning the relationships between applied materials, manufacturing methods, and interior architecture determined by porosity, pore shape, and size, and the mechanical, biological, chemical, and physical properties. Such a review is assumed to show the real achievements and, on the other side, shortages in so far research.

Additive Manufacturing: The Next Generation of Scapholunate Ligament Reconstruction

2021 ◽  
Author(s):  
Matthew N. Rush ◽  
Christina Salas ◽  
Lorraine Mottishaw ◽  
Damian Fountain ◽  
Deana Mercer
Keyword(s):  
Additive Manufacturing ◽  
Ligament Reconstruction ◽  
Three Dimensional ◽  
Biological Properties ◽  
Bone Interface ◽  
Significant Strength ◽  
Efficient Integration ◽  
Manufacturing Methods ◽  
Manufacturing Techniques ◽  
Manufacturing Technologies

Abstract Background Ligament reconstruction, as a surgical method used to stabilize joints, requires significant strength and tissue anchoring to restore function. Historically, reconstructive materials have been fraught with problems from an inability to withstand normal physiological loads to difficulties in fabricating the complex organization structure of native tissue at the ligament-to-bone interface. In combination, these factors have prevented the successful realization of nonautograft reconstruction. Methods A review of recent improvements in additive manufacturing techniques and biomaterials highlight possible options for ligament replacement. Description of Technique In combination, three dimensional-printing and electrospinning have begun to provide for nonautograft options that can meet the physiological load and architectures of native tissues; however, a combination of manufacturing methods is needed to allow for bone-ligament enthesis. Hybrid biofabrication of bone-ligament tissue scaffolds, through the simultaneous deposition of disparate materials, offer significant advantages over fused manufacturing methods which lack efficient integration between bone and ligament materials. Results In this review, we discuss the important chemical and biological properties of ligament enthesis and describe recent advancements in additive manufacturing to meet mechanical and biological requirements for a successful bone–ligament–bone interface. Conclusions With continued advancement of additive manufacturing technologies and improved biomaterial properties, tissue engineered bone-ligament scaffolds may soon enter the clinical realm.

Fabricating Hydroxyapatite–Silk Fibroin Nanocomposite by Bone Bionics

2007 ◽  
Vol 330-332 ◽  
pp. 345-348 ◽  
Author(s):  
Biao Cui ◽  
Lie Feng Liang ◽  
Xiao Ying Lu ◽  
Jie Weng
Keyword(s):  
Aqueous Solution ◽  
Silk Fibroin ◽  
Bone Structure ◽  
Organic Matrix ◽  
Bone Substitutes ◽  
Biological Properties ◽  
The Novel ◽  
Tissue Engineering Scaffolds ◽  
Preferential Growth ◽  
Woven Bone

In the present study, hydroxyapatite (HA) /silk fibroin (SF) nanocomposite containing 40 wt % of SF, was synthesized in an aqueous solution of CaCl2/(NH4)2HPO4 system containing SF to mimic bone structure of nano HA crystallites in organic matrix. The experimental results show that SF promotes the preferential growth of nano HA crystallites along the plane (002) which indicates the interaction between nano HA crystallites and SF. The nanocomposite with nano HA crystallites dispersed homogeneously in SF matrix possesses a compression strength of 97.6 MPa higher than that of woven bone. The methodology has a great potential for designing and engineering of biomaterials with improved biological properties. The novel nanocomposite may be used as bone substitutes and tissue engineering scaffolds.

scholarly journals A Review on Additive Manufacturing Possibilities for Electrical Machines

Energies ◽  
2021 ◽  
Vol 14 (7) ◽  
pp. 1940
Author(s):  
Muhammad Usman Naseer ◽  
Ants Kallaste ◽  
Bilal Asad ◽  
Toomas Vaimann ◽  
Anton Rassõlkin
Keyword(s):  
Additive Manufacturing ◽  
Large Scale ◽  
Three Dimensional ◽  
Electrical Machines ◽  
Electromagnetic Properties ◽  
Scale Production ◽  
Performance Parameters ◽  
Large Scale Production ◽  
One Step ◽  
Manufacturing Techniques

This paper presents current research trends and prospects of utilizing additive manufacturing (AM) techniques to manufacture electrical machines. Modern-day machine applications require extraordinary performance parameters such as high power-density, integrated functionalities, improved thermal, mechanical & electromagnetic properties. AM offers a higher degree of design flexibility to achieve these performance parameters, which is impossible to realize through conventional manufacturing techniques. AM has a lot to offer in every aspect of machine fabrication, such that from size/weight reduction to the realization of complex geometric designs. However, some practical limitations of existing AM techniques restrict their utilization in large scale production industry. The introduction of three-dimensional asymmetry in machine design is an aspect that can be exploited most with the prevalent level of research in AM. In order to take one step further towards the enablement of large-scale production of AM-built electrical machines, this paper also discusses some machine types which can best utilize existing developments in the field of AM.

scholarly journals Development of a 3D Printable and Highly Stretchable Ternary Organic-Inorganic Nanocomposite Hydrogel

2021 ◽  
Author(s):  
Chen Hu ◽  
Malik Haider ◽  
Lukas Hahn ◽  
Mengshi Yang ◽  
Robert Luxenhofer
Keyword(s):  
Mechanical Properties ◽  
Additive Manufacturing ◽  
Nanocomposite Hydrogel ◽  
Highly Stretchable ◽  
Manufacturing Techniques ◽  
Advanced Applications

Hydrogels that can be processed with additive manufacturing techniques and concomitantly possess favorable mechanical properties are interesting for many advanced applications. However, the development of novel ink materials with high...

scholarly journals Additive manufacturing of PLA-based scaffolds intended for bone regeneration and strategies to improve their biological properties

e-Polymers ◽  
2020 ◽  
Vol 20 (1) ◽  
pp. 571-599
Author(s):  
Ricardo Donate ◽  
Mario Monzón ◽  
María Elena Alemán-Domínguez
Keyword(s):  
Mechanical Properties ◽  
Tissue Engineering ◽  
Additive Manufacturing ◽  
Bone Regeneration ◽  
Polylactic Acid ◽  
State Of The Art ◽  
Biological Properties ◽  
Design Stage ◽  
Bone Scaffolds ◽  
Regeneration Of Bone

AbstractPolylactic acid (PLA) is one of the most commonly used materials in the biomedical sector because of its processability, mechanical properties and biocompatibility. Among the different techniques that are feasible to process this biomaterial, additive manufacturing (AM) has gained attention recently, as it provides the possibility of tuning the design of the structures. This flexibility in the design stage allows the customization of the parts in order to optimize their use in the tissue engineering field. In the recent years, the application of PLA for the manufacture of bone scaffolds has been especially relevant, since numerous studies have proven the potential of this biomaterial for bone regeneration. This review contains a description of the specific requirements in the regeneration of bone and how the state of the art have tried to address them with different strategies to develop PLA-based scaffolds by AM techniques and with improved biofunctionality.

scholarly journals Advances in 3D Printing for Tissue Engineering

Materials ◽  
2021 ◽  
Vol 14 (12) ◽  
pp. 3149
Author(s):  
Angelika Zaszczyńska ◽  
Maryla Moczulska-Heljak ◽  
Arkadiusz Gradys ◽  
Paweł Sajkiewicz
Keyword(s):  
Tissue Engineering ◽  
Additive Manufacturing ◽  
3D Printing ◽  
Complex Structure ◽  
Three Dimensional ◽  
Computer Assisted ◽  
Scaffold Fabrication ◽  
Manufacturing Techniques ◽  
Printing Techniques ◽  
State Of Art

Tissue engineering (TE) scaffolds have enormous significance for the possibility of regeneration of complex tissue structures or even whole organs. Three-dimensional (3D) printing techniques allow fabricating TE scaffolds, having an extremely complex structure, in a repeatable and precise manner. Moreover, they enable the easy application of computer-assisted methods to TE scaffold design. The latest additive manufacturing techniques open up opportunities not otherwise available. This study aimed to summarize the state-of-art field of 3D printing techniques in applications for tissue engineering with a focus on the latest advancements. The following topics are discussed: systematics of the available 3D printing techniques applied for TE scaffold fabrication; overview of 3D printable biomaterials and advancements in 3D-printing-assisted tissue engineering.

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