scholarly journals New Oral Surgery Materials for Bone Reconstruction—A Comparison of Five Bone Substitute Materials for Dentoalveolar Augmentation

Materials ◽  
2020 ◽  
Vol 13 (13) ◽  
pp. 2935 ◽  
Author(s):  
Marcin Kozakiewicz ◽  
Tomasz Wach
Keyword(s):  
Tricalcium Phosphate ◽  
Bone Substitute ◽  
Oral Surgery ◽  
Calcium Phosphates ◽  
Bone Replacement ◽  
Living Bone ◽  
Bone Substitute Materials ◽  
Occurrence Matrix ◽  
Radiological Image ◽  
Substitute Materials

This article presents a comparison of bone replacement materials in terms of their ability to produce living bone image at the place of their implantation. Five bone replacement materials are compared (Osteovit—porous collagen, Cerasorb Foam—collagen scaffolding of synthetic β tricalcium phosphate, Osbone—synthetic hydroxyapatite, Endobone—deproteinized bovine-derived cancellous bone hydroxyapatite, and Cerasorb—synthetic β tricalcium phosphate). Intraoral radiographs are taken immediately after implantation and 12 months later. The texture analysis was performed to assess (texture index, TI) the level of structure chaos (entropy) in relation to the presence of longitudinal elements visible in radiographs (run length emphasis moment). The reference ratio of the chaotic trabecular pattern (Entropy) to the number of longitudinal structures, i.e., trabeculae (LngREmph), is 176:100 (i.e., 1.76 ± 0.28). Radiological homogeneity immediately after the implantation procedure is a result of the similar shape of its particles (Osbone, Endobone and Cerasorb) or radiolucency (Osteovit, Cerasorb Foam). The particles visible in radiographs were similar in the LngREmph parameters applied to the reference bone, but not in the co-occurrence matrix features. The TI for Osteovit during a 12-month follow-up period changed from 1.55 ± 0.26 to 1.48 ± 0.26 (p > 0.05), for Cerasorb Foam from 1.82 ± 0.27 to 1.63 ± 0.24 (p < 0.05), for Osbone from 1.97 ± 0.31 to 1.74 ± 0.30 (p < 0.01), and for Endobone from 1.86 ± 0.25 to 1.84 ± 0.25 (p > 0.05), The observed structure in the radiological image of bone substitute materials containing calcium phosphates obtains the characteristics of a living bone image after twelve months.

scholarly journals Biological Properties of Calcium Phosphate Bioactive Glass Composite Bone Substitutes: Current Experimental Evidence

2019 ◽  
Vol 20 (2) ◽  
pp. 305 ◽  
Author(s):  
Maria Karadjian ◽  
Christopher Essers ◽  
Stefanos Tsitlakidis ◽  
Bruno Reible ◽  
Arash Moghaddam ◽  
...  
Keyword(s):  
Bone Substitute ◽  
Calcium Phosphates ◽  
Donor Site ◽  
Bone Substitutes ◽  
Biological Properties ◽  
Recent Experimental Data ◽  
Bone Substitute Materials ◽  
Autologous Bone ◽  
Substitute Materials ◽  
Composite Bone

Standard treatment for bone defects is the biological reconstruction using autologous bone—a therapeutical approach that suffers from limitations such as the restricted amount of bone available for harvesting and the necessity for an additional intervention that is potentially followed by donor-site complications. Therefore, synthetic bone substitutes have been developed in order to reduce or even replace the usage of autologous bone as grafting material. This structured review focuses on the question whether calcium phosphates (CaPs) and bioactive glasses (BGs), both established bone substitute materials, show improved properties when combined in CaP/BG composites. It therefore summarizes the most recent experimental data in order to provide a better understanding of the biological properties in general and the osteogenic properties in particular of CaP/BG composite bone substitute materials. As a result, BGs seem to be beneficial for the osteogenic differentiation of precursor cell populations in-vitro when added to CaPs. Furthermore, the presence of BG supports integration of CaP/BG composites into bone in-vivo and enhances bone formation under certain circumstances.

scholarly journals Fast-Versus Slow-Resorbable Calcium Phosphate Bone Substitute Materials—Texture Analysis after 12 Months of Observation

Materials ◽  
2020 ◽  
Vol 13 (17) ◽  
pp. 3854
Author(s):  
Tomasz Wach ◽  
Marcin Kozakiewicz
Keyword(s):  
Wavelet Transform ◽  
Texture Analysis ◽  
Bone Substitute ◽  
Oral Surgery ◽  
Healing Process ◽  
High Rate ◽  
Discrete Wavelet ◽  
Oral Surgical Procedures ◽  
Bone Substitute Materials ◽  
Substitute Materials

The development of oral surgery and implantology has led to the need for better and more predictable materials. Various substitute materials are now used for bone regeneration. The replacement of scaffolding material by new bone tissue is the most important condition. This study aimed to evaluate the effects of the resorbability of bone substitute materials during regeneration to the jawbone. The study included 88 patients during the 12-month follow-up. All the patients had undergone oral surgical procedures using two different substitute materials—Cerasorb (high-rate resorbable (β-tricalcium phosphate)) and Endobone (low-rate resorbable (hydroxyapatite)). Texture analysis was performed in intraoral radiographs, in which regions of interest were established for the bone substitute materials and reference bone. Five texture features were calculated, namely the sum average (SumAverg), entropy (Entropy), and three Harr discrete wavelet transform coefficients. This study revealed that all 5 features described the healing process well. Entropy was decreased in both cases with time; however, in Cerasorb cases, the texture feature values were very close to those of the reference bone after 12 months of healing (p < 0.05). The wavelet transform coefficient at scale 6 also showed that longitudinal objects appeared in implantation sites, similar to trabecular bone (p < 0.05) after 12 months of healing. The slow-resorbing material restored the structure of the alveolar crest better in terms of producing large objects similar to the components of a barrel bone image (wavelet coefficients), but required a longer time for reconstruction. The fast-resorbing material showed a texture image with a similar scattering of structures to that of the reference bone (entropy) after 12 months.

In Vivo Osteogenesis Assessment of a Tricalcium Phosphate Paste and a Tricalcium Phosphate Foam Bone Grafting Materials

2014 ◽  
Vol 631 ◽  
pp. 426-429 ◽  
Author(s):  
Marco A. Lopez-Heredia ◽  
Dirk Barnewitz ◽  
Antje Genzel ◽  
Michael Stiller ◽  
Fabian Peters ◽  
...  
Keyword(s):  
Tricalcium Phosphate ◽  
Bone Grafting ◽  
Clinical Performance ◽  
Calcium Phosphates ◽  
Bone Substitute Materials ◽  
Bone Grafting Materials ◽  
Reconstruction Of Bone Defects ◽  
Grafting Materials ◽  
Substitute Materials

Calcium phosphates (CaPs) are synthetic bone grafting materials. CaPs are an alternative to overcome the drawbacks present with autologous bone grafting and/or xenograft materials. Among the CaPs, tricalcium phosphate (TCP) stands out as a good candidate due to its physicochemical properties. The clinical performance of β-TCP has already been proven and established. Nevertheless, the format in which TCP is delivered is also important in terms of clinical handling. This work assessed the in vivo performance of TCP-based bone grafting materials with different formats. Materials studied were a TCP paste (TCP-P), a TCP foam (TCP-F) and TCP granules (TCP-G). A sheep scapula model was used to evaluate the osteogenic performance of these bone grafting materials. All materials performed well in terms of bone regenerative capacity and material resorption. However, TCP-P and TCP-F displayed a more pronounced initial material resorption and also exhibited better handling properties compared to TCP-G. TCP-based materials with improved handling properties, such as TCP-P and TCP-F, which at the same time possess the advantageous properties of β-TCP are suitable bone substitute materials for grafting and reconstruction of bone defects in numerous clinical applications.

Bone Substitute Materials in Modern Dentistry

2017 ◽  
Vol 1 (4) ◽  
Author(s):  
Andrius Geguzis ◽  
Inesa Astramskaite ◽  
Dovile Gabseviciute
Keyword(s):  
Bone Substitute ◽  
Bone Substitute Materials ◽  
Substitute Materials

In vitro effects of particulate bone substitute materials on the resorption activity of human osteoclasts

2017 ◽  
Vol 34 ◽  
pp. 291-306 ◽  
Author(s):  
G Russmueller ◽  
◽  
L Winkler ◽  
R Lieber ◽  
R Seemann ◽  
...  
Keyword(s):  
Bone Substitute ◽  
Bone Substitute Materials ◽  
In Vitro Effects ◽  
Substitute Materials ◽  
Human Osteoclasts
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