scholarly journals Relationship between the Surface Roughness of Biodegradable Mg-Based Bulk Metallic Glass and the Osteogenetic Ability of MG63 Osteoblast-Like Cells

Materials ◽  
2020 ◽  
Vol 13 (5) ◽  
pp. 1188 ◽  
Author(s):  
Pei-Chun Wong ◽  
Sin-Mao Song ◽  
Pei-Hua Tsai ◽  
Yi-Yuan Nien ◽  
Jason Shian-Ching Jang ◽  
...  
Keyword(s):  
Surface Roughness ◽  
Metallic Glass ◽  
Bulk Metallic Glass ◽  
Orthopedic Implants ◽  
Critical Issue ◽  
Degradation Behavior ◽  
Adhesion Ability ◽  
Mineral Deposition ◽  
First Contact ◽  
The Relationship

Mg-based bulk metallic glass materials have been investigated for their large potential for application in orthopedic implants due to their biocompatibility, low degradation rate, and osteogenetic ability. As an orthopedic implant, initial cell adhesion has been a critical issue for subsequent osteogenesis and bone formation because the first contact between cells and the implant occurs upon the implants surface. Here, we aimed to create Mg-based bulk metallic glass samples with three different surface roughness attributes in order to understand the degradation behavior of Mg-based bulk metallic glass and the adhesion ability and osteogenetic ability of the contact cells. It was found that the degradation behavior of Mg66Zn29Ca5 bulk metallic glass was not affected by surface roughness. The surface of the Mg66Zn29Ca5 bulk metallic glass samples polished via #800 grade sandpaper was found to offer a well-attached surface and to provide a good cell viability environment for Human MG63 osteoblast-like cell line. In parallel, more calcium and mineral deposition was investigated on extracellular matrix with higher surface roughness that verify the relationship between surface roughness and cell performance.

scholarly journals Experimental Study on Machinability of Zr-Based Bulk Metallic Glass during Micro Milling

Micromachines ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 86 ◽  
Author(s):  
Tao Wang ◽  
Xiaoyu Wu ◽  
Guoqing Zhang ◽  
Bin Xu ◽  
Yinghua Chen ◽  
...  
Keyword(s):  
Surface Roughness ◽  
Metallic Glass ◽  
Bulk Metallic Glass ◽  
Feed Rate ◽  
Rotation Speed ◽  
Amorphous Structure ◽  
Micro Milling ◽  
Depth Of Cut ◽  
Milling Force ◽  
Coated Cemented Carbide

The micro machinability of Zr41.2Ti13.8Cu12.5Ni10Be22.5 bulk metallic glass (BMG) was investigated by micro milling with coated cemented carbide tools. The corresponding micro milling tests on Al6061 were conducted for comparison. The results showed that the tool was still in stable wear stage after milling 300 mm, and the surface roughness Ra could be maintained around 0.06 μm. The tool experienced only slight chipping and rubbing wear after milling the BMG, while a built-up edge and the coating peeling off occurred severely when milling Al6061. The influence of rotation speed on surface roughness was insignificant, while surface roughness decreased with the reduction of feed rate, and then increased dramatically when the feed rate was below 2 μm/tooth. The surface roughness increased gradually with the axial depth of cut (DOC). Milling force decreased slightly with the increase in rotation speed, while it increased with the increase in axial DOC, and the size effect on milling force occurred when the feed rate decreased below 1 μm/tooth. The results of X-ray diffraction (XRD) showed that all milled surfaces were still dominated by an amorphous structure. This study could pave a solid foundation for structural and functional applications.

scholarly journals Machinability and Surface Generation of Pd40Ni10Cu30P20 Bulk Metallic Glass in Single-Point Diamond Turning

Micromachines ◽  
2019 ◽  
Vol 11 (1) ◽  
pp. 4 ◽  
Author(s):  
Jie Xiong ◽  
Hao Wang ◽  
Guoqing Zhang ◽  
Yanbing Chen ◽  
Jiang Ma ◽  
...  
Keyword(s):  
Surface Roughness ◽  
Metallic Glass ◽  
Bulk Metallic Glass ◽  
Tool Path ◽  
Single Point ◽  
Chip Morphology ◽  
Diamond Turning ◽  
Surface Generation ◽  
Workpiece Material ◽  
Machined Surface

Pd40Ni10Cu30P20 bulk metallic glass (BMG) is widely used in industrial fields due to its excellent oxidation resistance, corrosion resistance, and thermal stability. However, the lack of research on the machinability and cutting performance of BMG using single-point diamond turning (SPDT) limits its application for engineering manufacturing. In the present research, a series of turning experiments were carried out under different cutting parameters, and the machinability reflected by the quality of machined surface, chip morphology, and tool wear were analyzed. Based on the oxidation phenomenon of the machined surface, a molecular dynamics (MD) simulation was conducted to study the mechanism and suppression of the machined surface oxidation during the cutting. The results show that: (1) The Pd-based BMG had good machinability, where the machined surface roughness could go down to 3 nm; (2) irregular micro/nanostructures were found along the tool path on the outer circular region of the machined surface, which greatly affected the surface roughness; and (3) the cutting heat softened the workpiece material and flattened the tool marks under surface tension, which improved the surface quality. This research provides important theoretical and technical support for the application of BMG in optical mold manufacturing.

Investigation on Cutting Forces and Surface Finish in Mechanical Micro Milling of Zr-Based Bulk Metallic Glass

2019 ◽  
Vol 18 (01) ◽  
pp. 113-132
Author(s):  
Debajyoti Ray ◽  
Asit Baran Puri ◽  
Nagahanumaiah
Keyword(s):  
Surface Roughness ◽  
Metallic Glass ◽  
Cutting Force ◽  
Bulk Metallic Glass ◽  
Cutting Parameters ◽  
Milling Process ◽  
Spindle Speed ◽  
Micro Milling ◽  
Depth Of Cut ◽  
Axial Depth

Precision micro-component fabrication demands suitable manufacturing processes that ensure making of parts with good form and finish. Mechanical micro milling represents a flexible and powerful process that exhibits enhanced capability to create micro features. Bulk metallic glass (BMG) represents a young class of amorphous alloy material with superior mechanical and physical properties and finds appreciable micro scale applications like biomedical devices and implants, micro parts for sport items and various other micro- components. In the present work, an attempt has been made to analyze the influence of the cutting parameters like spindle speed, feed per tooth and axial depth of cut on the machinability of BMG, in mechanical micro-milling process. The micro-milling process performances have been evaluated concerning to cutting forces and surface roughness generated, by making full slots on the workpiece with solid carbide end mill cutters. The paper presents micro-machining results for bulk metallic glass machined with commercial micro-milling tool at low cutting velocity regime. Response surface methodology (RSM) has been employed for process modeling and subsequent analysis to study the influence of the combination of cutting parameters on responses within the selected domain of cutting parameters. It has been found that the effect of axial depth of cut on the cutting force components is remarkably significant. Cutting force components increases with the increase in axial depth of cut and decreases with increase in spindle speed. At low feed rate, cutting force in the feed direction (Fx, i.e., cutting force along x-direction) increases with a decrease in feed rate. This increase of force could be due to the possible ploughing effect. A similar pattern of variation has been observed with cutting force component in cross-feed direction (Fy) also. It has been found that effect of feed per tooth on the roughness parameter Ra is remarkably significant. Surface roughness increases with feed per tooth. Axial depth of cut does not contribute much to the surface roughness. Surface roughness decrease with the increase of spindle speed.

scholarly journals Biocompatibility and Osteogenic Capacity of Mg-Zn-Ca Bulk Metallic Glass for Rabbit Tendon-Bone Interference Fixation

2019 ◽  
Vol 20 (9) ◽  
pp. 2191 ◽  
Author(s):  
Chin-Chean Wong ◽  
Pei-Chun Wong ◽  
Pei-Hua Tsai ◽  
Jason Shian-Ching Jang ◽  
Cheng-Kung Cheng ◽  
...  
Keyword(s):  
Titanium Alloy ◽  
Metallic Glass ◽  
Bulk Metallic Glass ◽  
Osteogenic Potential ◽  
Migration Assay ◽  
Mineral Deposition ◽  
Conventional Titanium Alloy ◽  
Titanium Alloy Ti6al4v

Mg-based alloys have great potential for development into fixation implants because of their highly biocompatible and biodegradable metallic properties. In this study, we sought to determine the biocompatibility of Mg60Zn35Ca5 bulk metallic glass composite (BMGC) with fabricated implants in a rabbit tendon–bone interference fixation model. We investigated the cellular cytotoxicity of Mg60Zn35Ca5 BMGC toward rabbit osteoblasts and compared it with conventional titanium alloy (Ti6Al4V) and polylactic acid (PLA). The results show that Mg60Zn35Ca5 BMGC may be classed as slightly toxic on the basis of the standard ISO 10993-5. We further characterized the osteogenic effect of the Mg60Zn35Ca5 BMGC extraction medium on rabbit osteoblasts by quantifying extracellular calcium and mineral deposition, as well as cellular alkaline phosphatase activity. The results of these tests were found to be promising. The chemotactic effect of the Mg60Zn35Ca5 BMGC extraction medium on rabbit osteoblasts was demonstrated through a transwell migration assay. For the in vivo section of this study, a rabbit tendon–bone interference fixation model was established to determine the biocompatibility and osteogenic potential of Mg60Zn35Ca5 BMGC in a created bony tunnel for a period of up to 24 weeks. The results show that Mg60Zn35Ca5 BMGC induced considerable new bone formation at the implant site in comparison with conventional titanium alloy after 24 weeks of implantation. In conclusion, this study revealed that Mg60Zn35Ca5 BMGC demonstrated adequate biocompatibility and exhibited significant osteogenic potential both in vitro and in vivo. These advantages may be clinically beneficial to the development of Mg60Zn35Ca5 BMGC implants for future applications.

The relationship between t-ZrO2 stability and the crystallization of a Zr-based bulk metallic glass during oxidation

2012 ◽  
Vol 31 ◽  
pp. 21-25 ◽  
Author(s):  
Dongya Huang ◽  
Lu Huang ◽  
Bin Wang ◽  
Vincent Ji ◽  
Tao Zhang
Keyword(s):  
Metallic Glass ◽  
Bulk Metallic Glass ◽  
The Relationship

Study on surface roughness and top burr of micro-milled Zr-based bulk metallic glass in shear dominant zone

2020 ◽  
Vol 107 (9-10) ◽  
pp. 4287-4299
Author(s):  
Tao Wang ◽  
Xiaoyu Wu ◽  
Guoqing Zhang ◽  
Yinghua Chen ◽  
Bin Xu ◽  
...  
Keyword(s):  
Surface Roughness ◽  
Metallic Glass ◽  
Bulk Metallic Glass
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