scholarly journals Bone Augmentation and Simultaneous Implant Placement with Allogenic Bone Rings and Analysis of Its Purification Success

Materials ◽  
2019 ◽  
Vol 12 (8) ◽  
pp. 1291 ◽  
Author(s):  
Bernhard Giesenhagen ◽  
Nathalie Martin ◽  
Ole Jung ◽  
Mike Barbeck
Keyword(s):  
Alveolar Bone ◽  
Clinical Success ◽  
Bone Matrix ◽  
Allogeneic Bone ◽  
Bone Augmentation ◽  
Electron Microscopic ◽  
Clinical Images ◽  
Implant Placement ◽  
Freeze Dried ◽  
Scanning Electron

The main objective of this manuscript was to demonstrate the use of freeze-dried bone allografts (FDBA) by means of a technique of simultaneous bone augmentation and implant placement (“Bone Ring Technique”) in different indications, i.e., ridge reconstruction and sinus floor elevation procedure with a maxillary bone height of less than 4 mm. Moreover, cases with an up to 3-year follow-up were chosen to analyze the techniques of mid-term clinical success. Finally, the purification success of the FDBA was analyzed by means of established scanning electron microscopic (SEM) and histological methods. The FBDA bone ring was applied in three different patients and indications and presented; the healing success was analyzed on the basis of radiographical and clinical images. For analysis of the purification of the allogeneic bone, previously established histological methods and scanning electron microscopy (SEM) were applied. All analyzed patient cases showed that the FDBA-based bone ring was fully integrated into newly built alveolar bone. Furthermore, the observations revealed that the three-dimensional bone reconstructions in maxilla and mandible were stable within the observational period of up to 3 years. Altogether, the present data show that the application of the Bone Ring Technique using the FDBA rings allows for successful regeneration of alveolar bone with a predictable clinical outcome, functionality and esthetics. Moreover, the material analyses showed that the allogeneic bone tissue was free of cells or cell remnants, while the (ultra-) structure of the bone matrix has been retained. Thus, the biological safety of the FDBA has been confirmed.

Efficacy of Alveolar Ridge Preservation: A Randomized Controlled Trial

2020 ◽  
Vol 99 (4) ◽  
pp. 402-409 ◽  
Author(s):  
G. Avila-Ortiz ◽  
M. Gubler ◽  
M. Romero-Bustillos ◽  
C.L. Nicholas ◽  
M.B. Zimmerman ◽  
...  
Keyword(s):  
Tooth Extraction ◽  
Alveolar Bone ◽  
Controlled Trial ◽  
Control Group ◽  
Ridge Preservation ◽  
Alveolar Ridge ◽  
Bone Augmentation ◽  
Randomized Controlled ◽  
Implant Placement ◽  
Alveolar Ridge Preservation

Alveolar ridge preservation (ARP) therapy is indicated to attenuate the physiologic resorptive events that occur as a consequence of tooth extraction with the purpose of facilitating tooth replacement therapy. This randomized controlled trial was primarily aimed at testing the efficacy of ARP as compared with unassisted socket healing. A secondary objective was to evaluate the effect that local phenotypic factors play in the volumetric reduction of the alveolar bone. A total of 53 subjects completed the study. Subjects were randomized into either the control group, which involved only tooth extraction (EXT n = 27), or the experimental group, which received ARP using a combination of socket grafting with a particulate bone allograft and socket sealing with a nonabsorbable membrane (dPTFE) following tooth extraction (ARP n = 26). A set of clinical, linear, volumetric, implant-related, and patient-reported outcomes were assessed during a 14-wk healing period. All linear bone assessments (horizontal, midbuccal, and midlingual reduction) revealed that ARP is superior to EXT. Likewise, volumetric bone resorption was significantly higher in the control group (mean ± SD: EXT = −15.83% ± 4.48%, ARP = −8.36% ± 3.81%, P < 0.0001). Linear regression analyses revealed that baseline buccal bone thickness is a strong predictor of alveolar bone resorption in both groups. Interestingly, no significant differences in terms of soft tissue contour change were observed between groups. Additional bone augmentation to facilitate implant placement in a prosthetically acceptable position was deemed necessary in 48.1% of the EXT sites and only 11.5% of the ARP sites ( P < 0.004). Assessment of perceived postoperative discomfort at each follow-up visit revealed a progressive decrease over time, which was comparable between groups. Although some extent of alveolar ridge remodeling occurred in both groups, ARP therapy was superior to EXT as it was more efficacious in the maintenance of alveolar bone and reduced the estimated need for additional bone augmentation at the time of implant placement (ClinicalTrials.gov NCT01794806).

Developmental Disturbances of the Rat Molar Induced By Two Diphosphonates

1989 ◽  
Vol 3 (2) ◽  
pp. 234-240 ◽  
Author(s):  
N. Fouda ◽  
M. Caracatsanis ◽  
L. Hammarstrom
Keyword(s):  
Microscopic Examination ◽  
Alveolar Bone ◽  
Morphological Changes ◽  
Electron Microscopic Examination ◽  
Enamel Matrix ◽  
Electron Microscopic ◽  
Developmental Disturbances ◽  
Scanning Electron Microscopic ◽  
Rat Molar ◽  
Scanning Electron

Very few reports have been published about the effects of diphosphonates on the cells and tissues of developing teeth. The present study was designed to investigate possible morphological changes in ameloblasts and odontoblasts and relate these changes to defects in the enamel surface of erupted teeth. Young rats were injected subcutaneously with single or multiple doses of HEDP or Cl2MDP (10 mg P/kg b.w.). Light microscopic examination of developing maxillary first molars showed that single injections of HEDP or Cl2MDP induced subameloblastic cysts between the secretory ameloblasts and the developing enamel. The ameloblastic lining of the cysts contained numerous calcified deposits. A few days after injection, hypoplasias were seen in the enamel in areas previously occupied by cysts. In the erupted teeth, scanning electron microscopic examination revealed enamel hypoplasias which were mainly localized on the mesial sides of the cusps. In addition to the previously mentioned disturbances, multiple injections resulted in more extensive cysts, some of which contained non-mineralized enamel matrix. Inhibition of the mineralization of dentin and alveolar bone was also noticed.

scholarly journals Design Techniques to Optimize the Scaffold Performance: Freeze-dried Bone Custom-made Allografts for Maxillary Alveolar Horizontal Ridge Augmentation

2020 ◽  
Author(s):  
Felice Roberto Grassi ◽  
Roberta Grassi ◽  
Leonardo Vivarelli ◽  
Dante Dallari ◽  
Marco Govoni ◽  
...  
Keyword(s):  
Clinical Success ◽  
Secondary Site ◽  
Autogenous Bone ◽  
Ridge Augmentation ◽  
Implant Placement ◽  
Freeze Dried ◽  
Custom Made ◽  
Atrophic Maxilla ◽  
Bone Level ◽  
Density Analysis

Background: The aim of the present investigation was to evaluate the clinical success of horizontal ridge augmentation in the severely atrophic maxilla (Cawood and Howell class IV) using freeze-dried custom made bone harvested from cadaver donors tibial hemiplateau and to analyze the marginal bone level gain prior dental implants placement at 9 months after bone grafting and before prosthetic rehabilitation. Methods: A 52-year-old woman received custom made bone grafts. Patient underwent CT scans 2 weeks prior and 9 months after surgery for graft volume and density analysis. Results: The clinical and radiographic bone observations showed a very low rate of resorption after bone graft and implant placement. Conclusions: The custom-made allograft material was a highly effective modality for restoring the alveolar horizontal ridge, resulting in this way to reduce the need to obtain autogenous bone from a secondary site with predictable procedure. Further studies are needed to investigate its behavior at longer time points.

Periodontal Repair in Dogs: Effect of Allogenic Freeze-Dried Demineralized Bone Matrix Implants on Alveolar Bone and Cementum Regeneration

1998 ◽  
Vol 69 (1) ◽  
pp. 26-33 ◽  
Author(s):  
Chong-Kwan Kim ◽  
Kyoo-Sung Cho ◽  
Seong-Ho Choi ◽  
Annamarie Prewett ◽  
Ulf M.E. Wikesjö
Keyword(s):  
Alveolar Bone ◽  
Demineralized Bone Matrix ◽  
Bone Matrix ◽  
Freeze Dried ◽  
Demineralized Bone

scholarly journals Alveolar Bone Augmentation

2014 ◽  
Vol 614 ◽  
pp. 89-94 ◽  
Author(s):  
Cena Dimova ◽  
Kiro Papakoca ◽  
Velko Papakoca
Keyword(s):  
Dental Implant ◽  
Tooth Extraction ◽  
Alveolar Bone ◽  
Bone Volume ◽  
The Body ◽  
Surgical Reconstruction ◽  
Bone Augmentation ◽  
Alveolar Ridge Augmentation ◽  
Ridge Augmentation ◽  
Implant Placement

Bones and teeth are the only structureswithin the body where calciumandphosphate participate asfunctional pillars. Despite their mineralnature, both organs are vital and dynamic. The aim was to remark the indications for alveolar augmentation after tooth extraction and prior the placement of endoosseous dental implants. The autograft, allograft, alloplast, and xenograftmaterials all have reported success, alone or in combination,for particulate bone augmentation. Theparticulate autograft is the gold standard for mostcraniofacial bone grafting, including the treatmentof dental implant–related defects. Advantages of alveolar ridge augmentation with sufficient bone volume to adjust for uncompromised and esthetic implant placement, renders these procedures more than effective for majority of patients. Surgical reconstruction of the tissues and the procedure of ridge augmentation and subsequent placement of dental implant are necessary.

Implant Installation With Bone Augmentation and Transmucosal Healing With Demineralized Human Cortical Bone in the Maxillary Anterior Region: Report of 3 Cases

2012 ◽  
Vol 38 (6) ◽  
pp. 762-766 ◽  
Author(s):  
Jun-Beom Park
Keyword(s):  
Demineralized Bone Matrix ◽  
Bone Matrix ◽  
Animal Experiments ◽  
Bone Augmentation ◽  
Implant Placement ◽  
Anterior Teeth ◽  
Tissue Changes ◽  
Term Basis ◽  
Immediate Implant ◽  
Soft Tissue Changes

It is well known that a decrease in vertical height and in horizontal width is seen after tooth extraction. Immediate implant placement, originally thought to prevent buccal wall resorption, showed little or no evident decrease of the resorption rate or pattern in animal experiments or clinical studies. Thus, the need for bone augmentation with immediate implantation has been suggested. However, until recently, simultaneous bone augmentation with immediate implant placement was thought to be possible only in a submerged environment. In this report, the harmony of soft and hard tissue was achieved in 3 patients by immediate implant placement and bone augmentation with transmucosal healing in esthetically challenging situations. Further evaluation is needed to monitor hard- and soft-tissue changes on a long-term basis. Implant placement and bone augmentation with transmucosal healing using demineralized bone matrix may be an option in the treatment of the loss of anterior teeth.

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