scholarly journals In Situ Controlled Surface Microstructure of 3D Printed Ti Alloy to Promote Its Osteointegration

Materials ◽  
2019 ◽  
Vol 12 (5) ◽  
pp. 815 ◽  
Author(s):  
Lijun Shan ◽  
Abdul Kadhum ◽  
M.S.H. Al-Furjan ◽  
Wenjian Weng ◽  
Youping Gong ◽  
...  
Keyword(s):  
3D Printing ◽  
Osteogenic Differentiation ◽  
Three Dimensional ◽  
Surface Characteristics ◽  
Ti Alloy ◽  
Differentiation Potential ◽  
Composite Surface ◽  
3D Printed ◽  
Printing Parameters

It is well known that three-dimensional (3D) printing is an emerging technology used to produce customized implants and surface characteristics of implants, strongly deciding their osseointegration ability. In this study, Ti alloy microspheres were printed under selected rational printing parameters in order to tailor the surface micro-characteristics of the printed implants during additive manufacturing by an in situ, controlled way. The laser path and hatching space were responsible for the appearance of the stripy structure (S), while the bulbous structure (B) and bulbous–stripy composite surface (BS) were determined by contour scanning. A nano-sized structure could be superposed by hydrothermal treatment. The cytocompatibility was evaluated by culturing Mouse calvaria-derived preosteoblastic cells (MC3T3-E1). The results showed that three typical microstructured surfaces, S, B, and BS, could be achieved by varying the 3D printing parameters. Moreover, the osteogenic differentiation potential of the S, B, and BS surfaces could be significantly enhanced, and the addition of nano-sized structures could be further improved. The BS surface with nano-sized structure demonstrated the optimum osteogenic differentiation potential. The present research demonstrated an in situ, controlled way to tailor and optimize the surface structures in micro-size during the 3D printing process for an implant with higher osseointegration ability.

A three-dimensional (3D) printing approach to fabricate an isolation chip for high throughput in situ cultivation of environmental microbes

Lab on a Chip ◽  
2022 ◽  
Author(s):  
Calvin Bok Sun Goh ◽  
Clariss Hui Peng Goh ◽  
Li Wen Wong ◽  
Wai Teng Cheng ◽  
Catherine Mary Yule ◽  
...  
Keyword(s):  
3D Printing ◽  
High Throughput ◽  
Three Dimensional ◽  
Petri Dish ◽  
Microbial Populations ◽  
Cultivation Method ◽  
3D Printed ◽  
Environmental Microbes

The 3D-printed iChip version made from thermoplastics or photopolymers can isolate microbial populations of a peat swamp in situ with a population profile different from that isolated via the standard in vitro Petri dish cultivation method.

scholarly journals Three-dimensional printing for heart diseases: clinical application review

2021 ◽  
Author(s):  
Yanyan Ma ◽  
Peng Ding ◽  
Lanlan Li ◽  
Yang Liu ◽  
Ping Jin ◽  
...  
Keyword(s):  
3D Printing ◽  
Clinical Application ◽  
Heart Diseases ◽  
Three Dimensional ◽  
Convincing Evidence ◽  
Surgical Interventions ◽  
Three Dimensional Printing ◽  
Complex Anatomy ◽  
Precise Understanding ◽  
3D Printed

AbstractHeart diseases remain the top threat to human health, and the treatment of heart diseases changes with each passing day. Convincing evidence shows that three-dimensional (3D) printing allows for a more precise understanding of the complex anatomy associated with various heart diseases. In addition, 3D-printed models of cardiac diseases may serve as effective educational tools and for hands-on simulation of surgical interventions. We introduce examples of the clinical applications of different types of 3D printing based on specific cases and clinical application scenarios of 3D printing in treating heart diseases. We also discuss the limitations and clinically unmet needs of 3D printing in this context.

scholarly journals Three-Dimensional Printing of Hydroxyapatite Composites for Biomedical Application

Crystals ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 353
Author(s):  
Yanting Han ◽  
Qianqian Wei ◽  
Pengbo Chang ◽  
Kehui Hu ◽  
Oseweuba Valentine Okoro ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
3D Printing ◽  
Biomedical Application ◽  
Three Dimensional ◽  
Antibacterial Properties ◽  
Natural Polymers ◽  
Three Dimensional Printing ◽  
3D Printed ◽  
Dental Applications ◽  
Hard Tissue Engineering

Hydroxyapatite (HA) and HA-based nanocomposites have been recognized as ideal biomaterials in hard tissue engineering because of their compositional similarity to bioapatite. However, the traditional HA-based nanocomposites fabrication techniques still limit the utilization of HA in bone, cartilage, dental, applications, and other fields. In recent years, three-dimensional (3D) printing has been shown to provide a fast, precise, controllable, and scalable fabrication approach for the synthesis of HA-based scaffolds. This review therefore explores available 3D printing technologies for the preparation of porous HA-based nanocomposites. In the present review, different 3D printed HA-based scaffolds composited with natural polymers and/or synthetic polymers are discussed. Furthermore, the desired properties of HA-based composites via 3D printing such as porosity, mechanical properties, biodegradability, and antibacterial properties are extensively explored. Lastly, the applications and the next generation of HA-based nanocomposites for tissue engineering are discussed.

scholarly journals Three-dimensionally printed polycaprolactone/multicomponent bioactive glass scaffolds for potential application in bone tissue engineering

2020 ◽  
Vol 6 (1) ◽  
pp. 57-69
Author(s):  
Amirhosein Fathi ◽  
Farzad Kermani ◽  
Aliasghar Behnamghader ◽  
Sara Banijamali ◽  
Masoud Mozafari ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
3D Printing ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Three Dimensional ◽  
Layer By Layer ◽  
Composite Scaffolds ◽  
3D Printed ◽  
Co Doped

AbstractOver the last years, three-dimensional (3D) printing has been successfully applied to produce suitable substitutes for treating bone defects. In this work, 3D printed composite scaffolds of polycaprolactone (PCL) and strontium (Sr)- and cobalt (Co)-doped multi-component melt-derived bioactive glasses (BGs) were prepared for bone tissue engineering strategies. For this purpose, 30% of as-prepared BG particles (size <38 μm) were incorporated into PCL, and then the obtained composite mix was introduced into a 3D printing machine to fabricate layer-by-layer porous structures with the size of 12 × 12 × 2 mm3.The scaffolds were fully characterized through a series of physico-chemical and biological assays. Adding the BGs to PCL led to an improvement in the compressive strength of the fabricated scaffolds and increased their hydrophilicity. Furthermore, the PCL/BG scaffolds showed apatite-forming ability (i.e., bioactivity behavior) after being immersed in simulated body fluid (SBF). The in vitro cellular examinations revealed the cytocompatibility of the scaffolds and confirmed them as suitable substrates for the adhesion and proliferation of MG-63 osteosarcoma cells. In conclusion, 3D printed composite scaffolds made of PCL and Sr- and Co-doped BGs might be potentially-beneficial bone replacements, and the achieved results motivate further research on these materials.

scholarly journals Tunable In Situ 3D-Printed PVDF-TrFE Piezoelectric Arrays

Sensors ◽  
2021 ◽  
Vol 21 (15) ◽  
pp. 5032
Author(s):  
Alec Ikei ◽  
James Wissman ◽  
Kaushik Sampath ◽  
Gregory Yesner ◽  
Syed N. Qadri
Keyword(s):  
3D Printing ◽  
Polyvinylidene Fluoride ◽  
Vinylidene Fluoride ◽  
Mechanical Strain ◽  
Pressure Sensors ◽  
Strain Ratio ◽  
Ex Situ ◽  
Order Of Magnitude ◽  
3D Printed

In the functional 3D-printing field, poly(vinylidene fluoride-co-trifluoroethylene) (PVDF-TrFE) has been shown to be a more promising choice of material over polyvinylidene fluoride (PVDF), due to its ability to be poled to a high level of piezoelectric performance without a large mechanical strain ratio. In this work, a novel presentation of in situ 3D printing and poling of PVDF-TrFE is shown with a d33 performance of up to 18 pC N−1, more than an order of magnitude larger than previously reported in situ poled polymer piezoelectrics. This finding paves the way forward for pressure sensors with much higher sensitivity and accuracy. In addition, the ability of in situ pole sensors to demonstrate different performance levels is shown in a fully 3D-printed five-element sensor array, accelerating and increasing the design space for complex sensing arrays. The in situ poled sample performance was compared to the performance of samples prepared through an ex situ corona poling process.

scholarly journals 3D printing of a bio-based ink made of cross-linked cellulose nanofibrils with various metal cations

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
J. Benedikt Mietner ◽  
Xuehe Jiang ◽  
Ulrica Edlund ◽  
Bodo Saake ◽  
Julien R. G. Navarro
Keyword(s):  
3D Printing ◽  
Divalent Cations ◽  
Cellulose Nanofibrils ◽  
Three Dimensional ◽  
Metal Cations ◽  
Cross Link ◽  
Cellulose Pulp ◽  
Freeze Dried ◽  
3D Printed ◽  
Metallic Cations

AbstractIn this work, we present an approach to cross-link cellulose nanofibrils (CNFs) with various metallic cations (Fe3+, Al3+, Ca2+, and Mg2+) to produce inks suitable for three-dimensional (3D) printing application. The printability of each hydrogel ink was evaluated, and several parameters such as the optimal ratio of Mn+:TOCNF:H2O were discussed. CNF suspensions were produced by mechanical disintegration of cellulose pulp with a microfluidizer and then oxidized with 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO). Finally, metal cations were introduced to the deprotonated TEMPO-oxidized CNF (TOCNF) suspension to cross-link the nanofibrils and form the corresponding hydrogels. The performances of each gel-ink were evaluated by rheological measurements and 3D printing. Only the gels incorporated with divalent cations Ca2+ and Mg2+ were suitable for 3D printing. The 3D printed structures were freeze-dried and characterized with Fourier transform infrared spectroscopy (FT-IR) and Scanning Electron Microscopy (SEM). The better interaction of the TOCNFs with the divalent metallic cations in terms of printability, the viscoelastic properties of the inks, and the variation trends owing to various metal cations and ratios are discussed.

APPLICATION OF 3D PRINTING TECHNOLOGY FOR RAPID TOOLING IN SHEET METAL FORMING

2020 ◽  
Vol 3 ◽  
pp. 20-30
Author(s):  
M.A. SEREZHKIN ◽  
D.O. KLIMYUK ◽  
A.I. PLOKHIKH
Keyword(s):  
3D Printing ◽  
Sheet Metal ◽  
Sheet Metal Forming ◽  
Metal Forming ◽  
Rapid Tooling ◽  
Printing Technology ◽  
3D Printing Technology ◽  
3D Printed ◽  
Printed Materials ◽  
Printing Parameters

The article presents the study of the application of 3D printing technology for rapid tooling in sheet metal forming for custom or small–lot manufacturing. The main issue of the usage of 3D printing technology for die tooling was discovered. It is proposed to use the method of mathematical modelling to investigate how the printing parameters affect the compressive strength of FDM 3D–printed parts. Using expert research methods, the printing parameters most strongly affecting the strength of products were identified for further experiments. A method for testing the strength of 3D–printed materials has been developed and tested.

A review on the role of 3D printing in the fight against COVID-19: safety and challenges

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Sapam Ningthemba Singh ◽  
Vavilada Satya Swamy Venkatesh ◽  
Ashish Bhalchandra Deoghare
Keyword(s):  
Supply Chain ◽  
3D Printing ◽  
Three Dimensional ◽  
Content Type ◽  
Medical Supplies ◽  
Future Challenges ◽  
Safety And Reliability ◽  
3D Printed ◽  
Comprehensive Study

Purpose During the COVID-19 pandemic, the three-dimensional (3D) printing community is actively participating to address the supply chain gap of essential medical supplies such as face masks, face shields, door adapters, test swabs and ventilator valves. This paper aims to present a comprehensive study on the role of 3D printing during the coronavirus (COVID-19) pandemic, its safety and its challenges. Design/methodology/approach This review paper focuses on the applications of 3D printing in the fight against COVID-19 along with the safety and challenges associated with 3D printing to fight COVID-19. The literature presented in this paper is collected from the journal indexing engines including Scopus, Google Scholar, ResearchGate, PubMed, Web of Science, etc. The main keywords used for searches were 3D printing COVID-19, Safety of 3D printed parts, Sustainability of 3D printing, etc. Further possible iterations of the keywords were used to collect the literature. Findings The applications of 3D printing in the fight against COVID-19 are 3D printed face masks, shields, ventilator valves, test swabs, drug deliveries and hands-free door adapters. As most of these measures are implemented hastily, the safety and reliability of these parts often lacked approval. The safety concerns include the safety of the printed parts, operators and secondary personnel such as the workers in material preparation and transportation. The future challenges include sustainability of the process, long term supply chain, intellectual property and royalty-free models, etc. Originality/value This paper presents a comprehensive study on the applications of 3D printing in the fight against COVID-19 with emphasis on the safety and challenges in it.

3 D printing technology and experimental study of chitosan gel using atomized solidification liquid-assisted extrusion molding

2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Yangwei Wang ◽  
Peilun Lv ◽  
Jian Li ◽  
Liying Yu ◽  
Guodong Yuan ◽  
...  
Keyword(s):  
3D Printing ◽  
Three Dimensional ◽  
Theoretical Research ◽  
Error Sources ◽  
Printing Technology ◽  
Content Type ◽  
Printing Ink ◽  
Printing Parameters ◽  
Chitosan Gel ◽  
Printing Method

Purpose This paper aims to propose a suitable atomizing solidification chitosan (CS) gel liquid extrusion molding technology for the three dimensional (3D) printing method, and experiments verify the feasibility of this method. Design/methodology/approach This paper mainly uses experimental means, combined with theoretical research. The preparation method, solidification forming method and 3D printing method of CS gel solution were studied. The CS gel printing mechanism and printing error sources are analyzed on the basis of the CS gel ink printing results, printing performance with different ratios of components by constructing a gel print prototype, experiments evaluating the CS gel printing technology and the effects of the process parameters on the scaffold formation. Findings CS printing ink was prepared; the optimal formula was found; the 3 D printing experiment of CS was completed; the optimal printing parameters were obtained; and the reliability of the forming prototype, printing ink and gel printing process was verified, which allowed for the possibility to apply the 3 D printing technology to the manufacturing of a CS gel structure. Originality/value This study can provide theoretical and technical support for the potential application of CS 3 D printed gels in tissue engineering.

Additive technology applied to the realization of K-band microwave terminations: reproducibility improvement

2018 ◽  
Vol 10 (1) ◽  
pp. 3-8
Author(s):  
Azar Maalouf ◽  
Ronan Gingat ◽  
Vincent Laur
Keyword(s):  
3D Printing ◽  
Frequency Band ◽  
Rectangular Waveguide ◽  
Three Dimensional ◽  
Low Density ◽  
Support Material ◽  
Additive Technology ◽  
3D Printed ◽  
K Band

This study examines K-band rectangular waveguide terminations with three-dimensional (3D)-printed loads, and proposes an Asymmetrical Tapered Wedge topology. This geometry shows a good tradeoff between microwave performance and 3D-printing issues (printing directions and support material requirements), thus improving noticeably the reproducibility of the devices. The effect of the density of the 3D-printed load on the reflection parameter of the termination was investigated. Even for a low density, reflection level remained below −27.5 dB between 18 and 26.5 GHz. Reproducibility was demonstrated by the characterization of six loads that were 3D printed under the same conditions. Measurements demonstrate that a maximum reflection parameter level of −33.5 dB can be ensured over the whole frequency band without any post-machining of the 3D-printed devices.

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