scholarly journals Enhanced Antibacterial Performance and Cytocompatibility of Silver Nanoparticles Stabilized by Cellulose Nanocrystal Grafted with Chito-Oligosaccharides

Materials ◽  
2018 ◽  
Vol 11 (8) ◽  
pp. 1339 ◽  
Author(s):  
Xiaohui Ni ◽  
Jinru Wang ◽  
Yiying Yue ◽  
Wanli Cheng ◽  
Dong Wang ◽  
...  

The agglomeration of silver nanoparticles (AgNPs) results in poor antibacterial performance, and the accumulation of silver in the human body threatens human health. Preparing a matrix is a technique worth considering as it not only prevents the aggregation of AgNPs but also reduces deposition of AgNPs in the human body. In this paper, carboxy-cellulose nanocrystals (CCNC) were prepared by a simple one-step acid hydrolysis method. Chito-oligosaccharides (CSos) were grafted onto the surface of CCNC to form CSos-CCNC composite nanoparticles. CCNC and CSos-CCNC were used as stabilizers for deposing AgNPs and two types of complexes—AgNPs-CCNC and AgNPs-CSos-CCNC—were obtained, respectively. The influence of the two stabilizer matrices—CCNC and CSos-CCNC—on the morphology, thermal behavior, crystal structure, antibacterial activity, and cell compatibility of AgNPs-CCNC and AgNPs-CSos-CCNC were examined. The results showed that the AgNPs deposited on the CSos-CCNC surface had a smaller average diameter and a narrower particle size distribution compared with the ones deposited on CCNC. The thermal stability of AgNPs-CSos-CCNC was better than that of AgNPs-CCNC. AgNPs did not affect the crystalline structure of CCNC and CSos-CCNC. The antibacterial activity of AgNPs-CSos-CCNC was better than that of AgNPs-CCNC based on antibacterial studies using Escherichia coli, Staphylococcus aureus, and Klebsiella pneumoniae. The cytotoxicity of AgNPs-CSos-CCNC was remarkably lower than that of AgNPs-CCNC.

2012 ◽  
Vol 602-604 ◽  
pp. 197-200
Author(s):  
Yong Qi Wei ◽  
Xin Chen ◽  
Ai Jun Han ◽  
Ming Quan Ye

The synthesis of nano-Ni/B composite particles was studied by diamine hydrate reducing nikel chloride in the water bath at 50 °C, in which nano-Ni was made to cover the surface of micron boron powder. The particle size, the structure and properities of the nano-Ni/B composite particles were characterized by scanning electron microscopy (SEM) and X-ray diffraction (XRD). And the thermal stability of nano-Ni/B composite particles was studied by employing thermogravimetry (TG), differential thermal analysis (DTA). The results showed that this method could prepare the compact coating for Ni/B particles. The nano-Ni particles coated on boron particle were uniform and continuous. The average diameter of Ni crystallites was about 21.7 nm. Compared with boron powders, the high temperature of exothermic peak of nano-Ni/B composite particles was decreased about 36 °C. The thermal chemistry behavior of the as-prepared nano-Ni/B composite particles was better than superfine boron powders.


2014 ◽  
Vol 137 ◽  
pp. 358-361 ◽  
Author(s):  
N. Jayaprakash ◽  
J. Judith Vijaya ◽  
L. John Kennedy ◽  
K. Priadharsini ◽  
P. Palani

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
R. S. Rimal Isaac ◽  
G. Sakthivel ◽  
Ch. Murthy

We report on rapid one-step green synthesis of gold and silver nanoparticles using fruit extract ofAverrhoa bilimbi Linn. UV-Vis absorption spectroscopy was used to monitor the quantitative formation of gold and silver nanoparticles. The characteristics of the obtained gold and silver nanoparticles were studied using UV-Vis absorption spectroscopy (UV/Vis), Fourier transform infrared spectroscopy (FTIR), Scanning electron microscopy (SEM), and Energy-dispersive spectroscopy (EDX). UV/Vis spectrum showed Surface Plasmon Resonance (SPR) for both gold and silver nanoparticles at 540 and 420 nm. The EDX spectrum of the solution containing gold and silver nanoparticles confirmed the presence of elemental gold and silver signals. The average diameter of the prepared nanoparticles in solution was about 50–150 nm. Synthesized particles were either hexagonal or rhomboidal in shape. This synthesis approach of gold and silver nanoparticles is cost effective and can be widely used in biological systems. The effect of fruit extract and metal ion concentration was also studied.


Molecules ◽  
2020 ◽  
Vol 26 (1) ◽  
pp. 130
Author(s):  
Fatimah Al-Otibi ◽  
Reem A. Al-Ahaidib ◽  
Raedah I. Alharbi ◽  
Rana M. Al-Otaibi ◽  
Gadah Albasher

The green biosynthesis of nanoparticles by plant extracts is an attractive and promising technique for medicinal applications. In the current study, we chose one of the daisy plants, Aaronsohnia factorovskyi (which grows in the Najd region, Saudi Arabia), to investigate its anti-microbial efficacy, in combination with silver nanoparticles. The biosynthesized nanoparticles were evaluated for antibacterial activity against Staphylococcus aureus, Bacillussubtilis (Gram-positive), Pseudomonas aeruginosa, and Escherichia coli, (Gram-negative) using the disc diffusion method, while the antifungal activity was assessed against Fusarium oxysporum, Fusarium solani, Helminthosporiumrostratum, and Alternariaalternata. The potential phytoconstituents of the plant extracts were identified by Fourier-transform infrared spectroscopy (FT-IR) techniques, the Field emission scanning electron microscopy (FE-SEM), Chromatography/Mass Spectrometry (GC-MS) techniques, and Zeta potential analysis. The current study revealed the ability of the tested plant extract to convert silver ions to silver nanoparticles with an average diameter of 104–140 nm. Biogenic Aaronsohnia factorovskyi-silver nanoparticles (AF-AgNPs) showed significant antibacterial activity against Staphylococcus aureus with inhibition zone diameter to 19.00 ± 2.94 mm, and antifungal activity against Fusarium solani, which reduced the growth of fungal yarn to 1.5 mm. The innovation of the present study is that the green synthesis of NPs, which is simple, cost-effective, provides stable nano-materials, and can be an alternative for the large-scale synthesis of silver nanoparticles.


2017 ◽  
Vol 19 (4) ◽  
pp. 128-136 ◽  
Author(s):  
Saviour A. Umoren ◽  
Alexis M. Nzila ◽  
Saravanan Sankaran ◽  
Moses M. Solomon ◽  
Peace S. Umoren

Abstract Silver nanoparticles (AgNPs) have been synthesized in the presence of Strawberry fruit extract (SBFE) at room temperature. The synthesized AgNPs was characterized by UV-vis spectroscopy, SEM, EDS, XRD, TEM and FTIR. The UV-vis spectra of the AgNPs show SPR band at 450 nm. TEM results indicate that AgNPs are spherical in shape and size range between 7–65 nm. Antibacterial activity of the synthesized AgNPs has been assessed against Pseudomonas aeruginosa and Bacillus licheniformis. The results show that AgNPs exhibit inhibitory effect and effect is a function of AgNPs concentration. The antibacterial activity of the prepared AgNPs has been compared with two antibiotics, amoxicillin and ciprofloxacin. It is found that the antibiotics perform better than AgNPs.


2019 ◽  
Vol 20 (1) ◽  
pp. 182
Author(s):  
Dian Susanthy ◽  
Sri Juari Santosa ◽  
Eko Sri Kunarti

This paper describes the antibacterial performance of silver nanoparticles (AgNPs) which have been synthesized by using p-aminobenzoic acid as reducing and stabilizing agent simultaneously. The silver nitrate with various concentrations was reacted with pH 11-adjusted p-aminobenzoic acid with a concentration of 5 × 10–3 mol L–1 for 30 min in a boiling water bath. The synthesized AgNPs were characterized by UV-Vis spectrophotometry, Transmission Electron Microscope (TEM), and Particle Size Analyzer (PSA). The antibacterial performance of the synthesized AgNPs was evaluated by agar well diffusion method on Escherichia coli and Staphylococcus aureus. The higher silver nitrate concentration, the bigger the nanoparticle size, the wider particle size distribution, and the higher number of AgNPs formed. AgNPs synthesized from higher silver nitrate concentration had higher antibacterial activity. It is an indication that the antibacterial activity of AgNPs is mainly controlled by the silver ion concentration which influences the AgNPs particle size and existence of silver ion in the AgNPs colloidal solution


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Oluwole S. Aremu ◽  
T. Qwebani-Ogunleye ◽  
Lebogang Katata-Seru ◽  
Zimbili Mkhize ◽  
John F. Trant

AbstractRespiratory tract infections arise due to the introduction of microbes into the airway, disrupting the normal, healthy, complex interdependent microbiome. The selective disruption of this community can be either beneficial or dangerous. Nanoparticles are a potential tool for modifying this population. Coated silver nanoparticles (AgNPs) were synthesized using ethanolic extracts of Hypoxis hemerocallidea (EEHH), a Southern African plant used extensively in traditional medicine and the source of many bioactive secondary metabolites. The room temperature reaction between silver nitrate and EEHH forms largely spherical AgNPs with an average diameter of 6–20 nm. These nanoparticles show similar levels of antibacterial activity as the broad-spectrum antibiotic streptomycin against Bacillus cereus, Streptococcus pneumonia, Escherichia coli, Pseudomonas aeuroginosa, and Moraxella catarrhalis. However, the AgNPs synergistically increase the antibacterial activity of streptomycin when they are applied in combination (30–52%). AgNPs are reiterated to be promising dual-function antibiotics, synergistically enhancing activity while also acting as delivery agents for small molecules.


2019 ◽  
Vol 55 (48) ◽  
pp. 6890-6893 ◽  
Author(s):  
Abhishek Gupta ◽  
Lara Holoidovsky ◽  
Chidambaram Thamaraiselvan ◽  
Amit K. Thakur ◽  
Swatantra P. Singh ◽  
...  

Silver nanoparticles embedded in laser-induced graphene surfaces were generated in a one step process, resulting in highly antibacterial surfaces.


Polymers ◽  
2019 ◽  
Vol 11 (7) ◽  
pp. 1185 ◽  
Author(s):  
Bishweshwar Pant ◽  
Mira Park ◽  
Soo-Jin Park

A new and straightforward route was proposed to incorporate silver nanoparticles (Ag NPs) into the surface of polyurethane nanofibers (PU NFs). Uniform distribution of in situ formed Ag NPs on the surface of PU NFs was achieved by adding AgNO3 and tannic acid in a PU solution prior to the electrospinning process. The synthesized nanofiber mats were characterized with state-of-the-art techniques and antibacterial performances were tested against Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) bacteria. The cytocompatibility and cell behavior were studied by using fibroblast cells. Following this preparation route, Ag/PU NFs can be obtained with excellent antibacterial performance, thus making them appropriate for various applications such as water filtration, wound dressings, etc.


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