scholarly journals Micro-Computed-Tomography-Guided Analysis of In Vitro Structural Modifications in Two Types of 45S5 Bioactive Glass Based Scaffolds

Materials ◽  
2017 ◽  
Vol 10 (12) ◽  
pp. 1341 ◽  
Author(s):  
Fabian Westhauser ◽  
Francesca Ciraldo ◽  
Preethi Balasubramanian ◽  
Anne-Sophie Senger ◽  
Gerhard Schmidmaier ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Bioactive Glass ◽  
Micro Computed Tomography ◽  
Structural Modifications

Feasibility, Safety, and Efficacy of Flow-Diverting Stent-Assisted Microsphere Embolization of Fusiform and Sidewall Aneurysms

Neurosurgery ◽  
2015 ◽  
Vol 77 (1) ◽  
pp. 126-136 ◽  
Author(s):  
Andrea Nonn ◽  
Stefanie Kirschner ◽  
Giovanna Figueiredo ◽  
Martin Kramer ◽  
Omid Nikoubashman ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Protection System ◽  
Micro Computed Tomography ◽  
Beam Hardening ◽  
Safety And Efficacy ◽  
Aneurysm Occlusion ◽  
Flow Diverting Stent ◽  
Microsphere Embolization

Abstract BACKGROUND: Treatment of wide-necked internal carotid artery aneurysms is frequently associated with incomplete occlusion and high recurrence rates. Furthermore, platinum coils cause strong beam-hardening artifacts, hampering subsequent image analyses. OBJECTIVE: To assess the feasibility, safety, and efficacy of flow-diverting, stent-assisted microsphere embolization of fusiform and sidewall aneurysms in vitro and in vivo. METHODS: Using a recirculating pulsatile in vitro flow model, 5 different aneurysm geometries (inner/outer curve, narrow/wide neck, and fusiform) were treated (each n = 1) by flow-diverting stent (FDS) implantation and subsequent embolization through a jailed microcatheter using calibrated microspheres (500–900 μm) larger than the pores of the FDS mesh. Treatment effects were analyzed angiographically and by micro computed tomography. The fluid of the in vitro model was filtered to ensure that no microspheres evaded the aneurysm. The experiment was repeated once in vivo. RESULTS: In vitro, all 5 aneurysms were safely and completely occluded by FDS-assisted microsphere embolization. Virtually complete aneurysm occlusion was confirmed by angiography and micro computed tomography. No microspheres escaped into the circulation. The experiment was successfully repeated in 1 pig with a sidewall aneurysm generated by vessel occlusion. An embolic protection system placed distally of the FDS in vitro and in vivo (each n = 1) contained no microspheres after the embolization. Thus, no microspheres were lost in the circulation, and the use of an embolic protection system seems feasible to provide additional safety. CONCLUSION: FDS-assisted microsphere embolization of fusiform and sidewall aneurysms is feasible and yields virtually complete aneurysm occlusion while avoiding coil-associated beam-hardening artifacts.

scholarly journals Influence of the calcium hydroxide paste vehicle on penetration into lateral canals

2018 ◽  
Vol 21 (3) ◽  
pp. 282
Author(s):  
Amanda Sousa Vidal ◽  
Daniele Aparecida Leão ◽  
Fernanda Mota Guimarães ◽  
Mariana Oliveira Gonçalves ◽  
Raissa Freitas Pinheiro ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Calcium Hydroxide ◽  
Propylene Glycol ◽  
Group Analysis ◽  
Distilled Water ◽  
Micro Ct ◽  
Micro Computed Tomography ◽  
Respective Group ◽  
Before And After

<p><strong>Objective: </strong>The aim of this study was to use Micro computed tomography (micro-CT) to evaluate the influence of the type of vehicle associated with calcium hydroxide on its ability to penetrate simulated lateral canals. <strong>Materials and methods:</strong> 30 acrylic blocks with simulated lateral canals comprising apical, middle and cervical thirds were used in the <em>in vitro</em> study. The blocks were divided into 3 groups (n = 10) according to the type of vehicle used (chlorhexidine, distilled water and propylene glycol) in the calcium hydroxide slurry, which was inserted in the respective group of simulated canals with a K# 30 file and then agitated with an ultrasonic tip. The blocks were scanned by micro-computed tomography (micro-CT) before and after insertion of the medication. The images obtained were reconstructed and analyzed to obtain the initial volume of lateral canals and the volume of medication that penetrated into them. <strong>Results:</strong> In the intragroup analysis, both distilled water and chlorhexidine 2% were observed to present statistical difference in all thirds of the canal. Propylene glycol showed no intragroup difference. In the inter-group analysis, the propylene glycol paste presented higher values of penetration into the simulated lateral canals than the other groups (p &lt;0.05). <strong>Conclusion:</strong> Propylene glycol used as vehicle of the calcium hydroxide paste provided better penetration results in simulated lateral canals.</p>

scholarly journals In vitro method for 3D morphometry of human articular cartilage chondrons based on micro-computed tomography

2018 ◽  
Vol 26 (8) ◽  
pp. 1118-1126 ◽  
Author(s):  
I. Kestilä ◽  
J. Thevenot ◽  
M.A. Finnilä ◽  
S.S. Karhula ◽  
I. Hadjab ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Articular Cartilage ◽  
Human Articular Cartilage ◽  
Micro Computed Tomography ◽  
In Vitro Method

Three-Dimensional Quantification of Calcium Salt-Composite Resorption (CSC) In Vitro by Micro-computed Tomography (Micro-CT)

JOM ◽  
2014 ◽  
Vol 66 (4) ◽  
pp. 559-565 ◽  
Author(s):  
T. Winkler ◽  
X. Y. Dai ◽  
G. Mielke ◽  
S. Vogt ◽  
H. Buechner ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Calcium Salt ◽  
Three Dimensional ◽  
Micro Ct ◽  
Micro Computed Tomography
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