Synthesis and Characterization of Novel Thiazolidinones and Thioxothiazolidinones Derived from Substituted Indole

Molbank ◽  
10.3390/m1284 ◽  
2021 ◽  
Vol 2021 (4) ◽  
pp. M1284
Author(s):  
Nawel Rekiba ◽  
Abdelmadjid Benmohammed ◽  
Sofiane Khanoussi ◽  
Ayada Djafri ◽  
Jérôme Thibonnet
Keyword(s):  
Biological Properties ◽  
Synthesis And Characterization ◽  
Indole Ring ◽  
Heterocyclic Derivatives

Based on recent discoveries concerning the numerous biological properties of thiazolidinones and thiosemicarbazones, new N-substituted heterocyclic derivatives have been designed by combining the indole ring with thioxothiazolidinone, thiazolidinone or thiosemicarbazone. Thus, a series of new thioxothiazolidinone, thiazolidinone, or thiosemicarbazone derivatives bearing indole-based moiety have been designed, synthesized, and developed in good yields.

scholarly journals The synthesis and characterization of some new diazoamino derivatives

2010 ◽  
Vol 16 (1) ◽  
pp. 89-95
Author(s):  
Mihaela Mocanu
Keyword(s):  
1H Nmr ◽  
Bioactive Compounds ◽  
Elemental Analysis ◽  
Analysis Data ◽  
Biological Properties ◽  
Synthesis And Characterization ◽  
Elemental Analysis Data ◽  
Spectral Measurements ◽  
Inflammatory Processes

The sulfonamidic moiety is much encountered in structures of bioactive compounds. In the present paper the studies on the sulfonamidated aryloxyalkylcarboxylic acids are extended by their attaching on certain substrata able to confer some special biological properties to the final products, such as anti-tumor and antioxidant actions useful in treating inflammatory processes, ulcer, convulsions and diabetes, as well as a herbicidal action. The stepwise syntheses of the sulfonamidated aryloxyalkylcarboxylic acid derivatives and their characterization by elemental analysis data and IR, 1H-NMR and UV-Vis spectral measurements are described. The newly obtained compounds could show potential pharmaceutical and herbicide properties.

scholarly journals Synthesis and characterization of new Oxazine , Thiazine and Pyrazol derived from chalcones

2014 ◽  
Vol 11 (2) ◽  
pp. 477-485 ◽  
Author(s):  
Baghdad Science Journal
Keyword(s):  
Nmr Spectroscopy ◽  
Hydrazine Hydrate ◽  
Elemental Analysis ◽  
Potassium Hydroxide ◽  
1H Nmr Spectroscopy ◽  
Room Temperature ◽  
Potassium Hydroxide Solution ◽  
Synthesis And Characterization ◽  
Heterocyclic Derivatives

In this study, chalcones were synthesis by condensing 2-acetylpyridine with aromatic aldehyde derivatives in dilute ethanolic potassium hydroxide solution at room temperature according to Claisen-Schmidt condensation. After that, new heterocyclic derivatives such as Oxazine, Thiazine and Pyrazol were synthesis by reaction between chalcones with urea, thiourea and hydrazine hydrate respectively scheme 1. All these compounds wrer characterization by FTIR, 1H-NMR spectroscopy and elemental analysis.

ChemInform Abstract: Synthesis and Characterization of New Heterocyclic Derivatives by Oxidation of 1-Amino-2-methylindoline.

ChemInform ◽  
2010 ◽  
Vol 32 (52) ◽  
pp. no-no
Author(s):  
L. Peyrot ◽  
M. Elkhatib ◽  
J. R. Vignalou ◽  
R. Metz ◽  
F. Elomar ◽  
...  
Keyword(s):  
Synthesis And Characterization ◽  
Heterocyclic Derivatives

Synthesis and characterization of new heterocyclic derivatives by oxidation of 1-amino-2-methylindoline

2001 ◽  
Vol 38 (4) ◽  
pp. 885-893 ◽  
Author(s):  
L. Peyrot ◽  
M. Elkhatib ◽  
J. R. Vignalou ◽  
R. Metz ◽  
F. Elomar ◽  
...  
Keyword(s):  
Synthesis And Characterization ◽  
Heterocyclic Derivatives

scholarly journals Analysis of New Piperidine Substituted Benzothiazole Crystalline Derivatives

2021 ◽  
Vol 37 (5) ◽  
pp. 1158-1166
Author(s):  
S.Syed Shafi ◽  
R. Rajesh ◽  
R. Subaash ◽  
S.Senthil kumar
Keyword(s):  
Heterocyclic Compounds ◽  
Biological Properties ◽  
Synthesis And Characterization ◽  
The Novel ◽  
Photoluminescence Spectra ◽  
Chemical Structures ◽  
Good Antibacterial Activity ◽  
Biological Studies ◽  
Crystalline Nature

Recently, heterocyclic compounds play important role in drug industries. The benzothiazole (BTA) is a bicyclic compound in heterocyclic because of their biological properties. In this paper the synthesis and characterization of benzothiazole were reported. The chemical structures of synthesized compounds were established based on spectral data of 1HNMR, 13CNMR, and IR. The mass of the novel compounds was established with the help of the LCMS test. The formation of the crystal was confirmed by powder XRD and the sharp peaks show the purity and crystalline nature of the samples. The photoluminescence spectra explain the optical property of the compound. The biological studies of synthesized compounds show that compound 5c possesses good antibacterial activity and compound 5d has good antifungal activity.

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