scholarly journals 7-Docosahexaenoyl-Quercetin

Molbank ◽  
10.3390/m1203 ◽  
2021 ◽  
Vol 2021 (2) ◽  
pp. M1203
Author(s):  
Sarah Mazzotta ◽  
Gabriele Carullo ◽  
Fabio Sciubba ◽  
Maria Enrica Di Cocco ◽  
Francesca Aiello

Fatty acids and polyphenols represent different classes of pharmacologically active molecules. Hybrid derivatives of these compounds are interesting therapeutic tools. They could be obtained using enzymatic approaches, which allow regioselective derivatizations. In this short note, the pancreatic porcine lipase was employed to mediate the regioselective synthesis of 7-docosahexaenoyl-quercetin was described. The C-7 regioisomer formation was confirmed by 1H-NMR experiment. Generally, in this approach the alcoholic OH- was preferred when present. Nevertheless, in this case, it was demonstrated that the hindrance of the acyl group is a variable to obtain a good regioselectivity in C-7 position, employing only one-step reaction.

2008 ◽  
Vol 59 (3) ◽  
pp. 273-276 ◽  
Author(s):  
Raluca Stan ◽  
Nicoleta Chira ◽  
Cristina Ott ◽  
Cristina Todasca ◽  
Emile Perez

Several catanionic organogelators derived from 1,3 :2,4-bis-O-(p-aminobenzylidene)-D-sorbitol (p-NH2-DBS) and hydroxy derivatives of natural fatty acids were synthesized, characterized and their gelation ability was evaluated. SEM observations of the xerogels formed by association of 1,3 :2,4-bis-O-(p-aminobenzylidene)-D-sorbitol and 12-hydroxystearic acid showed important modifications in the morphology and depend upon the nature of solvent as compared with the xerogels formed by each individual organogelator.


Plants ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 1219
Author(s):  
Marek Bunse ◽  
Peter Lorenz ◽  
Florian C. Stintzing ◽  
Dietmar R. Kammerer

The present study aimed at the identification and quantitation of phenolic compounds, fatty acids, and further characteristic substances in the seeds of Geum urbanum L. and Geum rivale L. For this purpose, individual components of extracts recovered with MeOH, CH2Cl2, and by cold-pressing, respectively, were characterized by HPLC-DAD/ESI-MSn and GC/MS and compared with reference compounds. For both Geum species, phenolic compounds, such as flavonoids and gallic acid derivatives, and triterpenes, such as saponins and their aglycones, were detected. Surprisingly, both Geum species revealed the presence of derivatives of the triterpenoid aglycons asiatic acid and madecassic acid, which were characterized for the first time in the genus Geum. Furthermore, the fatty acids of both species were characterized by GC–MS after derivatization. Both species showed a promising fatty-acid profile in terms of nutritional properties because of high proportions of unsaturated fatty acids. Linoleic acid and linolenic acid were most abundant, among other compounds such as palmitic acid and stearic acid. In summary, the present study demonstrates the seeds of G. urbanum and G. rivale to be a valuable source of unsaturated fatty acids and bioactive phenolics, which might be exploited for nutritional and cosmetic products and for phytotherapeutic purposes.


2009 ◽  
Vol 130 (10) ◽  
pp. 861-869 ◽  
Author(s):  
Elena E. Emelina ◽  
Aleksander A. Petrov ◽  
Stanislav I. Selivanov ◽  
Yulia V. Nelyubina ◽  
Mikhail Yu. Antipin

2003 ◽  
Vol 317 (2) ◽  
pp. 247-254 ◽  
Author(s):  
Noemı́ Ruiz-López ◽  
Enrique Martı́nez-Force ◽  
Rafael Garcés
Keyword(s):  

1979 ◽  
Vol 10 (29) ◽  
Author(s):  
A. N. GRINEV ◽  
N. V. ARKHANGEL'SKAYA ◽  
G. YA. URETSKAYA ◽  
A. A. STOLYARCHUK ◽  
P. A. GALENKO-YAROSHEVSKII

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