scholarly journals 2-(Fluoromethyl)-4,7-dimethoxy-1-methyl-1H-benzimidazole

Molbank ◽  
10.3390/m1129 ◽  
2020 ◽  
Vol 2020 (2) ◽  
pp. M1129
Author(s):  
Patrick Kielty ◽  
Pau Farràs ◽  
Dennis A. Smith ◽  
Fawaz Aldabbagh
Keyword(s):  
Free Radical ◽  
Title Compound ◽  
Methylene Fluoride

Selectfluor (1-chloromethyl-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(tetrafluoroborate)) substitutes the TEMPO free radical with fluorine on 4,7-dimethoxy-1-methyl-2-{[(2,2,6,6-tetramethylpiperidin-1-yl)oxy]methyl}-1H-benzimidazole to give the title compound in a 77% yield. A mechanism is proposed for the formation of this novel methylene fluoride.

scholarly journals 3-[1-(4-Bromophenyl)ethoxy]-2,2,5-trimethyl-4-phenyl-3-azahexane

2013 ◽  
Vol 69 (12) ◽  
pp. o1792-o1793
Author(s):  
Praveen Pitliya ◽  
Ray J. Butcher ◽  
A. Karim ◽  
Paul F. Hudrlik ◽  
Anne M. Hudrlik ◽  
...  
Keyword(s):  
Free Radical ◽  
Dihedral Angle ◽  
Torsion Angle ◽  
Title Compound ◽  
Ethoxy Group ◽  
Methyl Group ◽  
X Ray ◽  
Compound C ◽  
Butyl Group ◽  
Benzene Rings

The title compound, C22H30BrNO, is an alkoxyamine compound, an effective initiator in nitroxide-mediated free radical polymerization. It was prepared as a mixture of two diasteromers; the crystal for the X-ray analysis showed one of these as a pair ofR,SandS,Renantiomers. Thetert-butyl and isopropyl groups are in an almostanticonformation in the crystal [C—N—C—C torsion angle = −168.8 (1)°], and the methyl group of the ethoxy group is in an approximateantirelationship to thetert-butyl group. The dihedral angle between the phenyl and benzene rings is 33.12 (7)°. The Br atom is disordered over two positions, with occupancies of 0.9139 (16) and 0.0861 (16). In the crystal, weak C—H...Br contacts link the molecules into chains along [-110].

The pyrolysis of 6a,11b-Dihydro-7-thiabenzo[c]fluorene 7,7-dioxide and some of its derivatives

1968 ◽  
Vol 21 (6) ◽  
pp. 1571 ◽  
Author(s):  
W Davies ◽  
BC Ennis ◽  
QN Porter
Keyword(s):  
Free Radical ◽  
Title Compound ◽  
Compound A ◽  
Radical Rearrangement ◽  
Rearrangement Mechanism ◽  
Derivatives Of

It is shown that heat in the absence of a solvent converts the title compound into benzo[k,l]thioxanthen 7,7-dioxide, 7-thiabenzo[c]fluorene, and o-(1-naphthyl)-benzenesulphonic acid. From these results and a consideration of the related pyrolyses of the 3,10- and 1,8-dimethyl derivatives of the title compound, a free-radical rearrangement mechanism is proposed to explain the observations.

scholarly journals N-(3-Nitrophenyl)maleimide

2006 ◽  
Vol 62 (7) ◽  
pp. o2734-o2735 ◽  
Author(s):  
Rodolfo Moreno-Fuquen ◽  
Hoover Valencia ◽  
Zulay Diney Pardo ◽  
Richard D'Vries ◽  
Alan R. Kennedy
Keyword(s):  
Free Radical ◽  
Radical Polymerization ◽  
Title Compound ◽  
Free Radical Polymerization ◽  
Dihedral Angles ◽  
Asymmetric Unit ◽  
Compound C ◽  
Independent Molecules

The title compound, C10H6N2O4, belongs to a series of N-arylmaleimides, which can be used as photoinitiators for free-radical polymerization. The dihedral angles between the planes of the benzene and imide rings are 56.2 (1) and 52.9 (1)° in the two independent molecules in the asymmetric unit.

scholarly journals Crystal and molecular structure of 1-picryl-2-phenyl-2-(4-picrylamidophenyl)-diazenium betaine: analogy between a picramido group and an oxygen atom

2017 ◽  
Vol 72 (2) ◽  
pp. 89-94 ◽  
Author(s):  
Alexandru T. Balaban ◽  
Titus Constantinescu ◽  
Miron Teodor Caproiu ◽  
Michel Giorgi ◽  
Teodor Silviu Balaban
Keyword(s):  
Molecular Structure ◽  
Free Radical ◽  
Oxygen Atom ◽  
Single Crystal ◽  
Title Compound ◽  
Crystal And Molecular Structure ◽  
Diffraction Experiment ◽  
X Ray Diffraction ◽  
Stable Free Radical ◽  
X Ray

AbstractThe title compound is formed by a non-trivial reaction involving two molecules of the stable free radical 2,2-diphenyl-1-picryl-hydrazyl and one molecule of N-methoxy-picramide. We could now perform an X-ray diffraction experiment on a single crystal and can fully confirm the betaine structure which has a central quinonoid ring with alternating long and short bonds.

Potentiation of bromotrichloromethane hepatotoxicity in male rats exposed to 10 ppm dietary chlordecone: Electron Microscopic and biochemical study

1990 ◽  
Vol 48 (3) ◽  
pp. 284-285
Author(s):  
O. M. Faroon ◽  
R. W. Henry ◽  
M. G. Soni ◽  
H. M. Mehendale
Keyword(s):  
Free Radical ◽  
Biochemical Study ◽  
Prior Exposure ◽  
Male Rats ◽  
Cellular Injury ◽  
Low Doses ◽  
Mixed Function Oxidase ◽  
Electron Microscopic ◽  
Potent Inducer ◽  
Cellular Energy

Previous work has shown that mirex undergoes photolytic dechlorination to chlordecone (CD) (KeponeR) in the environment. Much work has shown that prior exposure to nontoxic levels of CD causes potentiation of hepatotoxicity and lethality of CCl4, BrCCl3 and other halomethane compounds. Potentiation of bromotrichloromethane hepatotoxicity has been associated with compounds that stimulate the activity of hepatic mixed-function oxidase (MFO). An increase in the metabolism of halomethane by the MFO to a free radical initiates peroxidative decomposition of membranal lipids ending in massive cellular injury. However, not all MFO inducers potentiate BrCCl3 hepatotoxicity. Potentiation by much larger doses of phenobarbital is minimal and th at by a more potent inducer of MFO, mirex, is negligible at low doses. We suggest that the CD and bromotrichloromethane interaction results in a depletion of cellular energy and thereby reducing the cellular ability to undergo mitosis.

Deaminative carbonylative thioesterification of activated alkylamines with thiophenols under transition-metal-free conditions

2021 ◽  
Author(s):  
Fengqian Zhao ◽  
Xiao-Feng Wu
Keyword(s):  
Free Radical ◽  
Transition Metal ◽  
Metal Free

A transition-metal-free radical carbonylation of activated alkylamines with thiophenols has been successfully developed. Various thioesters were selectively produced with moderate to good yields.

1120: Citrate and Vitamin E Blunt the SWL-Induced Free Radical Surge in an In-Vitro MDCK Cell Culture Model

2004 ◽  
Vol 171 (4S) ◽  
pp. 295-295
Author(s):  
Fernando C. Delvecchio ◽  
Ricardo M. Brizuela ◽  
Karen J. Byer ◽  
W. Patrick Springhart ◽  
Saeed R. Khan ◽  
...  
Keyword(s):  
Cell Culture ◽  
Free Radical ◽  
Vitamin E ◽  
Mdck Cell ◽  
Cell Culture Model ◽  
Culture Model

Prognostic significance of serum free radical level in head injury

2005 ◽  
Vol 2 (2) ◽  
pp. 107-109
Author(s):  
A. Mishra ◽  
M.F. Huda ◽  
V.P. Singh ◽  
S. Mohanty ◽  
A. Sodhi
Keyword(s):  
Free Radical ◽  
Head Injury ◽  
Prognostic Significance ◽  
Serum Free
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