scholarly journals Neuroimaging Studies of Nonsuicidal Self-Injury in Youth: A Systematic Review

Life ◽  
2021 ◽  
Vol 11 (8) ◽  
pp. 729
Author(s):  
Marcelo J. A. A. Brañas ◽  
Marcos S. Croci ◽  
Ana Beatriz Ravagnani Salto ◽  
Victoria F. Doretto ◽  
Eduardo Martinho ◽  
...  
Keyword(s):  
Systematic Review ◽  
Cognitive Processing ◽  
Emotional Processing ◽  
Suicide Attempts ◽  
Functional Neuroimaging ◽  
Imaging Modality ◽  
Structural Mri ◽  
Neural Pathways ◽  
Self Injury ◽  
Nonsuicidal Self Injury

Nonsuicidal self-injury (NSSI) is prevalent and affects mainly the youth population. It is prospectively associated with suicide attempts, making it a target for suicide prevention. Recently, several studies have investigated neural pathways of NSSI using neuroimaging. However, there is a lack of systematized appraisal of these findings. This systematic review aims to identify and summarize the main neuroimaging findings of NSSI in youth. We followed PRISMA statement guidelines and searched MEDLINE, APA PsycInfo, and Google Scholar databases for neuroimaging studies, irrespective of imaging modality, specifically investigating NSSI in samples with a mean age of up to 25 years old. Quality assessment was made using the Newcastle–Ottawa and Joanna Briggs Institute scales. The initial search retrieved 3030 articles; 21 met inclusion criteria, with a total of 938 subjects. Eighteen studies employed functional neuroimaging techniques such as resting-state and task-based fMRI (emotional, interpersonal exposure/social exclusion, pain, reward, and cognitive processing paradigms). Three studies reported on structural MRI. An association of NSSI behavior and altered emotional processing in cortico-limbic neurocircuitry was commonly reported. Additionally, alterations in potential circuits involving pain, reward, interpersonal, self-processing, and executive function control processes were identified. NSSI has complex and diverse neural underpinnings. Future longitudinal studies are needed to understand its developmental aspects better.

Nonsuicidal Self-Injury and Its Relation to Suicidal Behavior

2014 ◽  
Author(s):  
Joseph C. Franklin ◽  
Matthew K. Nock
Keyword(s):  
Suicidal Behavior ◽  
Predictive Power ◽  
Suicide Attempts ◽  
Strong Association ◽  
Future Directions ◽  
Suicidal Intent ◽  
Self Injury ◽  
Basic Features ◽  
Insight Into ◽  
Nonsuicidal Self Injury

Nonsuicidal self-injury (NSSI) is the direct and intentional destruction of one’s own body tissue in the absence of suicidal intent. Although NSSI itself is explicitly nonsuicidal, nearly half of individuals who engage in NSSI also engage in suicidal behavior, and nearly all individuals who engage in suicidal behavior also engage in NSSI. Moreover, recent studies suggest that NSSI is one of the strongest known predictors of future suicide attempts, even exceeding the predictive power of prior suicide attempts in some instances. In this chapter we review the basic features and correlates of NSSI, evaluate the evidence for traditional models of NSSI, and discuss how an emerging model of NSSI may provide insight into the strong association between NSSI and suicidal behavior. We conclude by recommending how to evaluate when NSSI is a behavioral emergency and by noting the most crucial future directions for research on this topic.

scholarly journals Psychotherapies for Adolescents with Subclinical and Borderline Personality Disorder: A Systematic Review and Meta-Analysis

2019 ◽  
Vol 65 (1) ◽  
pp. 5-15 ◽  
Author(s):  
Jennifer Wong ◽  
Anees Bahji ◽  
Sarosh Khalid-Khan
Keyword(s):  
Systematic Review ◽  
Borderline Personality Disorder ◽  
Personality Disorder ◽  
Suicide Attempts ◽  
Meta Analysis ◽  
Borderline Personality ◽  
Treatment Retention ◽  
Short Term ◽  
Self Injury

Background: Evidence regarding the efficacy of psychotherapy in adolescents with borderline personality disorder (BPD) symptomatology has not been previously synthesized. Objective: To conduct a systematic review and meta-analysis of the randomized controlled trials (RCTs) in order to assess the efficacy of psychotherapies in adolescents with BPD symptomatology. Methods: Seven electronic databases were systematically searched using the search terms BPD, adolescent, and psychotherapy from database inception to July 2019. Titles/abstracts and full-texts were screened by one reviewer; discrepancies were resolved via consensus. We extracted data on BPD symptomatology, including BPD symptoms, suicide attempts, nonsuicidal self-injury, general psychopathology, functional recovery, and treatment retention. Data were pooled using random-effects models. Results: Of 536 papers, seven trials (643 participants) were eligible. Psychotherapy led to significant short-term improvements in BPD symptomatology posttreatment ( g = −0.89 [−1.75, −0.02]) but not in follow-up ( g = 0.06 [−0.26, 0.39]). There was no significant difference in treatment retention between the experimental and control groups overall (odds ratio [ OR] 1.02, 95% confidence interval [CI], 0.92 to 1.12, I 2 = 52%). Psychotherapy reduced the frequency of nonsuicidal self-injury ( OR = 0.34, 95% CI, 0.16 to 0.74) but not suicide attempts ( OR = 1.03, 95% CI, 0.46 to 2.30). Conclusions: There is a growing variety of psychotherapeutic interventions for adolescents with BPD symptomatology that appears feasible and effective in the short term, but efficacy is not retained in follow-up—particularly for frequency of suicide attempts.

scholarly journals Nonsuicidal Self-injury: A Systematic Review

2017 ◽  
Vol 8 ◽  
Author(s):  
Annarosa Cipriano ◽  
Stefania Cella ◽  
Paolo Cotrufo
Keyword(s):  
Systematic Review ◽  
Self Injury ◽  
Nonsuicidal Self Injury

Suicide Attempts and Nonsuicidal Self-Injury in the Treatment of Resistant Depression in Adolescents: Findings from the TORDIA Study

2012 ◽  
Vol 10 (3) ◽  
pp. 380-388 ◽  
Author(s):  
Joan Rosenbaum Asarnow ◽  
Giovanna Porta ◽  
Anthony Spirito ◽  
Graham Emslie ◽  
Greg Clarke ◽  
...  
Keyword(s):  
Suicide Attempts ◽  
Self Injury ◽  
Resistant Depression ◽  
Nonsuicidal Self Injury
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