scholarly journals Overview of Important Micronutrients Supplementation in Preterm Infants after Discharge: A Call for Consensus

Life ◽  
2021 ◽  
Vol 11 (4) ◽  
pp. 331
Author(s):  
Laura Ilardi ◽  
Alice Proto ◽  
Federica Ceroni ◽  
Daniela Morniroli ◽  
Stefano Martinelli ◽  
...  

Preterm infants have a lower level of nutrient body stores and immature body systems, resulting in a higher risk of malnutrition. Imbalanced complementary feeding could lead to further risk of nutritional deficits and excesses. However, evidence on their nutritional requirements following hospital discharge is limited. When planning complementary feeding, appropriate micronutrient intake should be considered for their critical role in supporting various body functions. This narrative review summarizes the need for iron, zinc, vitamin D, calcium, phosphate and long-chain polyunsaturated fatty acids (LCPUFAs) supplementation in preterm infants during complementary feeding. Regarding iron and vitamin D, the scientific community is reaching an agreement on supplementation in some categories of prematures. On the contrary, there is still not enough evidence to detail possible recommendations for LCPUFAs, zinc, calcium and phosphorus supplementation. However, these micronutrients are paramount for preterms’ health: LCPUFAs can promote retinal and brain development while calcium and phosphorus supplementation is essential to prevent preterms’ metabolic bone disease (MBD). Waiting for a consensus on these micronutrients, it is clear how the knowledge of the heterogeneity of the prematures population can help adjust the nutritional planning regarding the growth rate, comorbidities and comprehensive clinical history of the preterm infant.

Doctor Ru ◽  
2021 ◽  
Vol 20 (10) ◽  
pp. 76-79
Author(s):  
N.L. Prokoptseva ◽  
◽  
N.A. Ilienkova ◽  
N.Yu. Grishkevich ◽  
E.G. Neyman ◽  
...  

Objective of the Paper: To describe a case history of the diagnosis and management of hypervitaminosis D in a 3-month baby. Key Points. Hypervitaminosis D can be caused either by intake of high doses of this product, or hypersensitivity to its toxic effects. This paper describes a clinical history of diagnosis and management of hypervitaminosis D in a 3-month baby boy. Medical history (daily intake of vitamin D in doses manifold exceeding the age-specific preventive dose for 2 months), laboratory tests (increased blood concentrations of 25-hydroxycholecalciferol and calcium, reduced parathormone levels) made it possible to diagnose hypervitaminosis D. The condition of the baby improved after withdrawal of vitamin D and therapy aiming at normalisation of the hydro-electrolytic balance and body functions. It was recommended not to take vitamin D until the 25-hydroxycholecalciferol level normalises. Conclusion. In order to prevent hypervitaminosis D, it is essential to strictly adhere to the preventive and therapeutic doses of vitamin D, preferably with blood calcidiol monitoring. Keywords: hypervitaminosis D, 25-hydroxycholecalciferol, intoxication, preventive dose, therapeutic dose.


1989 ◽  
Vol 8 (2) ◽  
pp. 225-233 ◽  
Author(s):  
Winston W. K. Koo ◽  
Reginald C. Tsang ◽  
Paul Succop ◽  
Susan K. Krug-Wispe ◽  
Diane Babcock ◽  
...  

2019 ◽  
Vol 86 (6) ◽  
pp. 725-731
Author(s):  
Supamit Ukarapong ◽  
Walter Zegarra ◽  
Cristina Navarrete ◽  
Tossaporn Seeherunvong ◽  
Gary Berkovitz

Author(s):  
Vamsi Chalasani ◽  
Sundar Shanmugam ◽  
Shankar Venkatasubramanian ◽  
Rithvik Ramesh

Background: Secondary hyperparathyroidism can present for the first time as myopathy in some patients. Strict vegans are at risk of vitamin D deficiency resulting in secondary hyperparathyroidism. A myopathic presentation may lead to investigations and misdiagnosis of neuromuscular disease, ratherthan a metabolic bone disease. Methods: We report a young lady presenting with severe progressive limb girdle pattern myopathy, with brisk reflexes and periphral neuropathy. Electrophysiology confirmed the presence of ,yopathy and neuropathy, and labaotorial evaluation revealed vitamin D deficiency and elevated parathormone levels. Results: She was supplemented with vitamin D, and on follow up was found to have a near complete improvement. Conclusion: Hence it is imperative to evaluate for vitamin D deficiency in all susceptible patients, especially with a history of strict vegetarianism.


PEDIATRICS ◽  
1949 ◽  
Vol 3 (4) ◽  
pp. 573-573
Author(s):  
LAWSON WILKINS

About 25 years ago Fuller Albright became interested in disorders of the parathyroid glands and other conditions disturbing calcium and phosphorus metabolism. It was in 1925 that the first parathyroid adenoma was removed in Vienna and in 1924 and 1925 that Hanson and Collip independently extracted the active principle of the parathyroid glands. Since this time Albright and a long retinue of coworkers have turned out a large number of classic papers clarifying the understanding of the actions of parathyroid hormone, vitamin D and dihydrotachysterol, the effects of various renal disorders upon phosphorus and calcium, and the nature of bone diseases such as osteitis fibrosa generalisata, osteoporosis, osteomalacia, Paget's disease and polyostatic fibrous dysplasia. The new monograph presents in clear and concise form the accumulation of a quarter century of investigations and gives Albright's views as they stand today.


Author(s):  
Zainab A Razak Al-Sharifi ◽  
Haider Abd Al Jabbar

Vitamin D assumes a part in the pathogenesis of asthma as it has an intense immunomodulatory impact following up on the cells of the innate immunity. It additionally decreases the danger of respiratory viral diseases which are critical initiators of asthma intensifications. Additionally,it potentiates the mitigating activity of corticosteroids which are viewed as the best controllers of asthma. To identify the recurrence of vitamin D inadequacy and lack among Iraqi asthmatic kids and to relate vitamin D levels to the seriousness of asthma. This case control study was directed on 50 asthmatic kids and 50 healthy controls. All were subjected to clinical history taking including history of sun introduction and asthma medication and full clinical examination. Laboratory investigations included estimation of serum calcium,serum alkaline phosphatase and serum 25-OH-D levels. There was a significant association between vitamin D deficiency and seriousness of asthma,yet there was no significant correlation between sun exposure and 25-OH-D level. Vitamin D deficiency is common in Iraqi children with asthma.Low levels of serum vitamin D are connected with high asthma seriousness,decreased asthma control.


JMS SKIMS ◽  
2011 ◽  
Vol 14 (2) ◽  
pp. 40-42
Author(s):  
Muzafar Maqsood Wani ◽  
Imtiaz Ahmed Wani

Major biologic function of activated vitamin D is to maintain normal blood levels of calcium and phosphorus, thus regulating bone mineralization. Research suggests that vitamin D may help in immunomodulation, regulating cell growth and 1,4 differentiation as well as some diverse unspecified functions. Overt vitamin D deficiency leads to hypocalcaemia, secondary hyperparathyroidism and increased bone turnover, which in prolonged and severe cases may cause rickets in children and osteomalacia in elderly.... JMS 2011;14(2):40-42


2013 ◽  
Author(s):  
Adodra Annika ◽  
Kouklinos Andreas ◽  
Julies Priscilla ◽  
Shaw Mathew ◽  
Jacobs Benjamin

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