scholarly journals Improved Deep Convolutional Neural Network to Classify Osteoarthritis from Anterior Cruciate Ligament Tear Using Magnetic Resonance Imaging

2021 ◽  
Vol 11 (11) ◽  
pp. 1163
Author(s):  
Mazhar Javed Awan ◽  
Mohd Shafry Mohd Rahim ◽  
Naomie Salim ◽  
Amjad Rehman ◽  
Haitham Nobanee ◽  
...  
Keyword(s):  
Anterior Cruciate Ligament ◽  
Magnetic Resonance ◽  
Cruciate Ligament ◽  
Area Under The Curve ◽  
Magnetic Resonance Images ◽  
Learning Rate ◽  
Receiver Operating Curve ◽  
Acl Tear ◽  
Anterior Cruciate ◽  
Sensitivity Specificity

Anterior cruciate ligament (ACL) tear is caused by partially or completely torn ACL ligament in the knee, especially in sportsmen. There is a need to classify the ACL tear before it fully ruptures to avoid osteoarthritis. This research aims to identify ACL tears automatically and efficiently with a deep learning approach. A dataset was gathered, consisting of 917 knee magnetic resonance images (MRI) from Clinical Hospital Centre Rijeka, Croatia. The dataset we used consists of three classes: non-injured, partial tears, and fully ruptured knee MRI. The study compares and evaluates two variants of convolutional neural networks (CNN). We first tested the standard CNN model of five layers and then a customized CNN model of eleven layers. Eight different hyper-parameters were adjusted and tested on both variants. Our customized CNN model showed good results after a 25% random split using RMSprop and a learning rate of 0.001. The average evaluations are measured by accuracy, precision, sensitivity, specificity, and F1-score in the case of the standard CNN using the Adam optimizer with a learning rate of 0.001, i.e., 96.3%, 95%, 96%, 96.9%, and 95.6%, respectively. In the case of the customized CNN model, using the same evaluation measures, the model performed at 98.6%, 98%, 98%, 98.5%, and 98%, respectively, using an RMSprop optimizer with a learning rate of 0.001. Moreover, we also present our results on the receiver operating curve and area under the curve (ROC AUC). The customized CNN model with the Adam optimizer and a learning rate of 0.001 achieved 0.99 over three classes was highest among all. The model showed good results overall, and in the future, we can improve it to apply other CNN architectures to detect and segment other ligament parts like meniscus and cartilages.

scholarly journals Tibial Plateau Slopes in Indian Patients with or without Anterior Cruciate Ligament Injury: A Magnetic Resonance Imaging Study

2016 ◽  
Vol 24 (3) ◽  
pp. 289-293 ◽  
Author(s):  
Shyam Sundar ◽  
Sarthak Patnaik ◽  
Bobur Ubaydullaev ◽  
Vinodh Kolandavelu ◽  
David Rajan
Keyword(s):  
Anterior Cruciate Ligament ◽  
Magnetic Resonance ◽  
Tibial Plateau ◽  
Cruciate Ligament ◽  
Acl Injury ◽  
Magnetic Resonance Images ◽  
Lateral Tibial Plateau ◽  
Indian Patients ◽  
Males And Females ◽  
Anterior Cruciate

Purpose To compare anterior cruciate ligament (ACL)–injured and ACL-intact patients as well as males and females in terms of tibial plateau slopes to determine their association with ACL injury. Methods Magnetic resonance images (MRI) of the knee of 310 male and 179 female skeletally mature Indian patients (mean age, 40 years) with (n=170+29) or without (n=140+150) ACL injury were reviewed. Their medial and lateral tibial plateau slopes (MTPS and LTPS), medial tibial plateau depth (MTPD), and lateral tibial plateau height (LTPH) were measured using MRI. Results The ACL-injured and ACL-intact groups were comparable in terms of MTPS (6.72° vs. 6.73°, p=0.07), LTPS (5.68° vs. 5.70°, p=0.09), MTD (1.74 vs. 1.73 mm, p=0.356), and LTH (2.21 vs. 2.22 mm, p=0.393). Males and females were also comparable in terms of MTPS and LTPS in both ACL-injured and ACL-intact groups. Conclusion ACL-injured and ACL-intact patients as well as males and females were comparable in terms of the tibial plateau slope parameters.

Treatment with Tiludronic Acid Helps Reduce the Development of Experimental Osteoarthritis Lesions in Dogs with Anterior Cruciate Ligament Transection Followed by Reconstructive Surgery: A 1-Year Study with Quantitative Magnetic Resonance Imaging

2010 ◽  
Vol 38 (1) ◽  
pp. 118-128 ◽  
Author(s):  
JEAN-PIERRE PELLETIER ◽  
ÉRIC TRONCY ◽  
THIERRY BERTAIM ◽  
DOMINIQUE THIBAUD ◽  
ANNE-CHRISTINE GOULET ◽  
...  
Keyword(s):  
Anterior Cruciate Ligament ◽  
Magnetic Resonance ◽  
Reconstructive Surgery ◽  
Cruciate Ligament ◽  
Cartilage Volume ◽  
Magnetic Resonance Images ◽  
Volume Loss ◽  
Anterior Cruciate ◽  
Cartilage Volume Loss ◽  
Acl Transection

Objective.To investigate over a 1-year period in dogs that underwent extracapsular stabilization surgery (ECS) following anterior cruciate ligament (ACL) transection: whether reconstructive surgery could prevent osteoarthritis (OA) progression and whether treatment with the bisphosphonate tiludronic acid (TA) could improve the chronic evolution of OA structural changes.Methods.ACL transection was performed on dogs on Day 0 and ECS on Day 28. Dogs were randomly divided into 2 groups: 15 received placebo and 16 were treated with TA (2 mg/kg subcutaneous injection) on Days 14, 28, 56, and 84. Magnetic resonance images were acquired on Days −10, 26, 91, 210, and 357, and cartilage volume was quantified. At sacrifice (Day 364), cartilage from femoral condyles and tibial plateaus was macroscopically and histologically evaluated. Expression levels of MMP-1, -3, -13, ADAMTS-4, -5, BMP-2, FGF-2, IGF-1, TGF-ß1, collagen type II, and aggrecan were determined using real-time RT-PCR.Results.The loss of cartilage volume observed after ACL transection stabilized following ECS. Thereafter, a gradual gain occurred, with the cartilage volume loss on the tibial plateaus reduced at Day 91 (p < 0.02) and Day 210 (p < 0.001) in the TA-treated dogs. At sacrifice, TA-treated dogs presented a reduction in the severity of macroscopic (p = 0.03 for plateaus) and histologic (p = 0.07 for plateaus) cartilage lesions, had a better preserved collagen network, and showed decreased MMP-13 (p = 0.04), MMP-1 and MMP-3 levels.Conclusion.Our findings indicate that in dogs with ACL transection, ECS greatly prevents development of cartilage volume loss. Treatment with TA provided an additional benefit of reducing the development of OA lesions.

scholarly journals Correlation Between Magnetic Resonance Imaging and Surgical Exploration of the Anterolateral Structures of the Acute Anterior Cruciate Ligament–Injured Knee

2019 ◽  
Vol 47 (5) ◽  
pp. 1186-1193 ◽  
Author(s):  
Edoardo Monaco ◽  
Camilo Partezani Helito ◽  
Andrea Redler ◽  
Giuseppe Argento ◽  
Angelo De Carli ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Anterior Cruciate Ligament ◽  
Magnetic Resonance ◽  
Cruciate Ligament ◽  
Preoperative Imaging ◽  
Resonance Imaging ◽  
Surgical Exploration ◽  
Highly Sensitive ◽  
Anterior Cruciate ◽  
Sensitivity Specificity

Background: Combined anterior cruciate ligament (ACL) and anterolateral ligament (ALL) reconstruction is associated with improved clinical outcomes as compared with isolated intra-articular reconstruction, but the indications are not precisely defined. It may be the case that patients with proven anterolateral injury on preoperative imaging are most likely to benefit, but the accuracy of magnetic resonance imaging (MRI) is not known. Purpose/Hypothesis: To evaluate the correlation between MRI and surgical exploration in acute ACL-injured knees. The hypothesis was that a positive correlation would be identified between imaging and surgical findings for ALL/capsule and iliotibial band (ITB) injuries and that MRI would be highly sensitive, specific, and accurate. Study Design: Cohort study (diagnosis); Level of evidence, 2. Methods: Between January and May 2016, patients presenting with acute ACL injuries were considered for study eligibility. Included patients underwent 1.5-T MRI, which was evaluated by 3 investigators who attributed a Ferretti grade of injury to the anterolateral structures. At the time of ACL reconstruction, a lateral exploration was undertaken, and macroscopic injuries were identified. An evaluation of correlation between MRI and surgical exploration findings was performed. Results: Twenty-six patients participated in the study, and 96% had an ALL/capsule injury. The sensitivity, specificity, and accuracy of MRI and the correlation ( K) with surgical exploration findings were as follows, respectively: any ALL/capsule abnormality—88%, 100%, 88.5%, and 0.47; differentiating partial or complete ALL/capsule tears—78.6%, 41.7%, 61.5%, and 0.23; ITB injuries—62.5%, 40%, 50%, and 0.27. The percentage agreement between MRI and surgical findings was 88% for ALL/capsule injury, 65% for ITB injury, and 53% for Ferretti grading. Conclusion: Surgical exploration demonstrates that injuries occur to the anterolateral structures in almost all acute ACL-injured knees. MRI is highly sensitive, specific, and accurate for detection of abnormalities of the ALL/capsule and shows a high percentage of agreement with surgical findings. MRI has low sensitivity, specificity, and accuracy for the diagnosis of ITB injury. The Ferretti grade could not be reliably established from MRI, and there was only fair agreement between MRI and surgical findings with respect to ITB abnormalities and determination of whether ALL/capsular tears were partial or complete.

Magnetic Resonance Signal Abnormalities within the Pericruciate Fat Pad: A Possible Secondary Sign for Acute Anterior Cruciate Ligament Tears

2017 ◽  
Vol 68 (4) ◽  
pp. 438-444 ◽  
Author(s):  
Ferdinando Draghi ◽  
Mario Torresi ◽  
Luigi Urciuoli ◽  
Salvatore Gitto
Keyword(s):  
Anterior Cruciate Ligament ◽  
Magnetic Resonance ◽  
Cruciate Ligament ◽  
Diagnostic Value ◽  
Fat Pad ◽  
Acl Tear ◽  
Arthroscopic Findings ◽  
Anterior Cruciate ◽  
Cruciate Ligament Tears ◽  
Secondary Signs

Purpose The study sought to investigate the presence of magnetic resonance (MR) signal alterations within the pericruciate fat pad in patients with an acute anterior cruciate ligament (ACL) tear as well as evaluate its diagnostic value in comparison with the main secondary signs of ACL tears. Methods Two musculoskeletal radiologists retrospectively reviewed knee MR examinations performed from May to October 2015. The ACL was considered as torn or intact based on either previous arthroscopic findings or unequivocal MR imaging interpretation if arthroscopic correlation was unavailable. Abnormalities of the pericruciate fat pad were evaluated as increased signal on the fluid-sensitive sequences; the main secondary signs of ACL tears were identified. Sensitivity and specificity were calculated for each sign. Results A total of 182 patients entered this study: 22 with an acute ACL tear, 160 with intact ACL. Signal hyperintensity of the pericruciate fat pad was demonstrated in all patients with an acutely torn ACL, resulting significantly different between individuals with intact ACL and those with ligament tear ( P < .0001). This sign was much more sensitive (100%) but less specific (72.5%-75%) than other secondary signs. Conclusions Signal hyperintensity of the pericruciate fat pad on the fluid-sensitive sequences is associated with acute ACL tears and could be considered as a possible indicator of these injuries.

scholarly journals Femur-tibia Angle and Patella-tibia Angle: New Indicators for Diagnosing Anterior Cruciate Ligament Tears in Magnetic Resonance Imaging

2021 ◽  
Author(s):  
Zeng Li ◽  
Mengyuan Li ◽  
Yan Du ◽  
Hai Jiang ◽  
Yuanchen Ma ◽  
...  
Keyword(s):  
Anterior Cruciate Ligament ◽  
Knee Joint ◽  
Cruciate Ligament ◽  
Area Under The Curve ◽  
Roc Curves ◽  
Youden Index ◽  
Control Group ◽  
Acl Tear ◽  
Anterior Cruciate ◽  
Arthroscopic Knee

Abstract Background: Torn anterior cruciate ligament (ACL) contributes to internal rotation of tibia. However, there is no indicator in MRI to reflect the rotation of knee joint. So the purpose of this study is to introduce two new measurements in MRI, femur-tibia angle (FTA) and patella-tibia angle (PTA), which reflect the rotation of knee joint and assess their role in diagnosing ACL tears.Methods: Present study retrospectively reviewed the cases of primary arthroscopic knee surgery from January 2018 to December 2019 from the Arthroscopy Database at Guangdong Provincial People's Hospital. Firstly, comparisons of different measurements were conducted between the ACL tears group and isolated meniscus injury group. Then, the measurements were tested in diagnosing complete or partial ACL tears. Diagnostic performance of different measurements was assessed by area under the curve (AUC) of receiver operating characteristic (ROC) curve and cutoff values were determined by Youden index. Results: FTA and PTA in ACL tears group had 4.79 and 7.36 degrees more than that of control group (p = 0.022 and < 0.001, respectively). Besides, ACL angle and distance of anterior tibial subluxation (D) also showed significant differences (p<0.05). In distinguishing complete ACL tear with intact ACL, the ROC curves indicated that ACL angle had the highest AUC of 0.906 (95% CI: 0.833-0.978) while AUC of PTA was 0.849 (95% CI: 0.763-0.936) and AUC of FTA was 0.809 (95% CI: 0.710-0.908). In distinguishing partial ACL tear with intact ACL, the ROC curves showed that FTA and PTA had the highest AUCs of 0.847 and 0.813 with 95% CI of 0.737-0.957 and 0.680-0.947, respectively. In contrast, the AUCs of ACL angle and D were only 0.519 and 0.387 with 95% CI of 0.292-0.745 and 0.227-0.546.Conclusion: Present study introduced two new quantitative parameters, FTA and PTA, to assess the rotation of knee joint. FTA and PTA increased when ACL tears and they might be valuable in diagnosing ACL tears, especially in distinguishing partial ACL tear with intact ACL which was poorly diagnosed in MRI.

scholarly journals Relationship between intercondylar notch angle and anterior cruciate ligament injury: a magnetic resonance imaging analysis

2019 ◽  
Vol 47 (4) ◽  
pp. 1602-1609 ◽  
Author(s):  
Mengquan Huang ◽  
Yubiao Li ◽  
Naiming Guo ◽  
Chunlai Liao ◽  
Bin Yu
Keyword(s):  
Anterior Cruciate Ligament ◽  
Magnetic Resonance ◽  
Cruciate Ligament ◽  
Acl Injury ◽  
Tibial Slope ◽  
Magnetic Resonance Images ◽  
Ligament Injury ◽  
Intercondylar Notch ◽  
Notch Angle ◽  
Anterior Cruciate

Objectives This study was performed to compare the intercondylar notch angle (INA) and tibial slope in patients with and without anterior cruciate ligament (ACL) injury and determine the risk factors and influence of these anatomic variations on ACL injury. Methods Participants with and without non-contact ACL injuries were included in the patient and control groups, respectively. The INA (formed by the femoral axis and Blumensaat line), lateral tibial slope (LTS), and medial tibial slope (MTS) were measured on magnetic resonance images. Comparisons were performed between the two groups. A binary logistic regression model was used to determine the influence of the variables on ACL injury. Results Fifty-two participants were included in each group. The INA was significantly smaller and the LTS was significantly greater in the patients than in the controls. No difference was found in the MTS between the two groups. The area under the receiver operating characteristic curve for the combination of the INA and LTS was 0.776 (95% confidence interval, 0.688–0.864). Conclusions The INA was smaller and the LTS was greater in patients with than without ACL tears. The INA in combination with the LTS could be used to predict ACL injury.

The Incidence of Kaplan Fiber Injury Associated With Acute Anterior Cruciate Ligament Tear Based on Magnetic Resonance Imaging

2020 ◽  
Vol 48 (13) ◽  
pp. 3194-3199
Author(s):  
Niv Marom ◽  
Harry G. Greditzer ◽  
Michael Roux ◽  
Daphne Ling ◽  
Caroline Boyle ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Anterior Cruciate Ligament ◽  
Magnetic Resonance ◽  
Interrater Reliability ◽  
Cruciate Ligament ◽  
Resonance Imaging ◽  
Intrarater Reliability ◽  
Mri Scan ◽  
Acl Tear ◽  
Anterior Cruciate

Background: Kaplan fibers are distinct deep layers of the distal iliotibial band (ITB) that anchor the ITB to the distal femur and have a role in rotational stability of the knee. However, the incidence of Kaplan fiber injury in the setting of acute anterior cruciate ligament (ACL) tear is unknown. Purpose: To determine the reliability of identifying and evaluating Kaplan fibers on magnetic resonance imaging (MRI) examinations based on previously reported characteristics and to report on the incidence of combined ACL and Kaplan fiber injuries based on MRI examinations. Study Design: Cohort study (diagnosis); Level of evidence, 3. Methods: Patients with an acute primary ACL tear who obtained a postinjury MRI scan at our institution and were treated with ACL reconstruction between January 1, 2007, and May 31, 2012, were identified from an institutional registry. Each patient’s postinjury MRI scan was reviewed by 2 musculoskeletal radiologists, who identified Kaplan fibers and graded them as intact, injured, or not visualized. Intrarater reliability was measured using the intraclass correlation coefficient (ICC), and interrater reliability was measured using the kappa statistic. Results: A total of 72 patients were identified. For the proximal Kaplan fibers, 50% versus 58% were identified as injured, 32% versus 29% were identified as intact, and 18% versus 13% were not visualized by radiologist 1 and 2, respectively. For the distal Kaplan fibers, 46% versus 60% were identified as injured, 43% versus 28% were identified as intact, and 11% versus 12% were not visualized by radiologist 1 and 2, respectively. The ICC intrarater reliability measurements were 0.89 (95% CI, 0.83-0.93) for proximal Kaplan fibers and 0.66 (95% CI, 0.51-0.78) for distal Kaplan fibers. The interrater reliability measurements for both radiologists showed substantial agreement (kappa = 0.7) for proximal Kaplan fibers and moderate agreement (kappa = 0.51) for distal Kaplan fibers. Conclusion: Kaplan fibers were visualized on MRI studies in the majority of cases, with substantial reliability for the proximal fibers and moderate reliability for the distal fibers. There was an associated injury to either the proximal or distal or both Kaplan fibers in the majority of acute primary ACL tears.

The Role of Magnetic Resonance Imaging for Diagnosing Soft Tissue Lesions Associated with Anterior Cruciate Ligament Injuries

2018 ◽  
Vol 69 (9) ◽  
pp. 2498-2500
Author(s):  
Bogdan Sendrea ◽  
Antoine Edu ◽  
George Viscopoleanu
Keyword(s):  
Magnetic Resonance Imaging ◽  
Anterior Cruciate Ligament ◽  
Magnetic Resonance ◽  
Soft Tissue ◽  
Traumatic Event ◽  
Cruciate Ligament ◽  
Soft Tissue Injuries ◽  
Resonance Imaging ◽  
Soft Tissue Lesions ◽  
Anterior Cruciate

Magnetic resonance imaging has become the gold standard for soft tissue lesions evaluation especially after a traumatic event where there is need for diagnostic confirmation. The objective of the current paper was to evaluate the ability of magnetic resonance imaging in diagnosing soft tissue lesions in patients who underwent anterior cruciate ligament reconstruction compared with arthroscopic findings. Through the ability to diagnose soft tissue injuries, particularly meniscal lesions, magnetic resonance imaging should be considered as fundamental in guiding therapeutic management in patients with anterior cruciate ligament lesions.

Clinical Implications of Bone Bruise Patterns Accompanying Anterior Cruciate Ligament Tears

2021 ◽  
pp. 194173812110295
Author(s):  
Patrick Ward ◽  
Peter Chang ◽  
Logan Radtke ◽  
Robert H. Brophy
Keyword(s):  
Magnetic Resonance Imaging ◽  
Anterior Cruciate Ligament ◽  
Magnetic Resonance ◽  
Functional Outcomes ◽  
Cruciate Ligament ◽  
Acl Injury ◽  
Bone Bruise ◽  
Resonance Imaging ◽  
Bone Bruises ◽  
Anterior Cruciate

Background: Anterior cruciate ligament (ACL) tears are common injuries; they are often associated with concomitant injuries to other structures in the knee, including bone bruises. While there is limited evidence that bone bruises are associated with slightly worse clinical outcomes, the implications of bone bruises for the articular cartilage and the risk of developing osteoarthritis (OA) in the knee are less clear. Recent studies suggest that the bone bruise pattern may be helpful in predicting the presence of meniscal ramp lesions. Evidence Acquisition: A literature review was performed in EMBASE using the keyword search phrase (acl OR (anterior AND cruciate AND ligament)) AND ((bone AND bruise) OR (bone AND contusion) OR (bone AND marrow AND edema) OR (bone AND marrow AND lesion) OR (subchondral AND edema)). Study Design: Clinical review. Level of Evidence: Level 4. Results: The literature search returned 93 articles of which 25 were ultimately included in this review. Most studies identified a high prevalence of bone bruises in the setting of acute ACL injury. Individual studies have found relationships between bone bruise volume and functional outcomes; however, these results were not supported by systematic review. Similarly, the literature has contradictory findings on the relationship between bone bruises and the progression of OA after ACL reconstruction. Investigations into concomitant injury found anterolateral ligament and meniscal ramp lesions to be associated with bone bruise presence on magnetic resonance imaging. Conclusion: Despite the ample literature identifying the prevalence of bone bruises in association with ACL injury, there is little evidence to correlate bone bruises to functional outcomes or progression of OA. Bone bruises may best be used as a marker for concomitant injury such as medial meniscal ramp lesions that are not always well visualized on magnetic resonance imaging. Further research is required to establish the longitudinal effects of bone bruises on ACL tear recovery. Strength of Recommendation Taxonomy: 2.

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