scholarly journals Reappraisal of the Prognostic Factors of Outcome and Recovery Time in Patients with Idiopathic Bell’s Palsy: A Retrospective Single-Center Analysis

2021 ◽  
Vol 11 (3) ◽  
pp. 171
Author(s):  
Chi-Hao Peng ◽  
Jiun-Liang Chen ◽  
Ming-Feng Liao ◽  
Jung-Lung Hsu ◽  
Hui-Ching Hsu ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Recovery Time ◽  
Bell’S Palsy ◽  
Final Outcome ◽  
Favorable Outcome ◽  
Chang Gung Memorial Hospital ◽  
Bell's Palsy ◽  
Oral Glucocorticoid ◽  
Grade Ii ◽  
Different Doses

Study Objectives: This retrospective study investigated prognostic factors and recovery time in patients with Bell’s palsy after different doses and durations of oral glucocorticoid treatments. Subjects and Methods: A total of 396 patients initially diagnosed with Bell’s palsy that had visited the Department of Neurology of Chang Gung Memorial Hospital, Taoyuan, a tertiary referral medical center in Taiwan, between January 2014 and December 2018 were included. Medical records, facial electroneurography (fENoG), and blink reflex (BR) tests were reviewed and analyzed. A favorable outcome was defined as patients who improved to grade ≤ II, and an unfavorable outcome was defined as patients who improved to grade ≥ III in 6 months according to the House–Brackmann (HB) grading system. Results: The rate of favorable outcomes was 89.4% (354 of 396 patients) at the 6-month follow-up. A favorable outcome (HB less than grade II) was associated with a delayed BR (odds ratio, OR, 5.38; 95% CI, 1.82 to 15.90) and fENoG values (the lesion side/the healthy side) over 33% (OR, 6.67; 95% CI, 3.02 to 14.71). The recovery time was significantly shorter for those with a delayed BR than for those with an absent BR and shorter for those with good fENoG values (>33%) than for those with poor values (≤33%). However, treatment without or with different doses and durations of oral glucocorticoid did not influence the final outcome or recovery time in this study. Conclusions: The fENoG and BR tests were significant and highly valuable examinations for predicting the final outcome. Moreover, age younger than 60 years, a delayed BR, and fENoG values > 33% were associated with shorter recovery times.

Clinical Prediction of the Prognostic Factors for Recovery of Bell's Palsy

2019 ◽  
Author(s):  
Myung Chul Yoo ◽  
Yunsoo Soh ◽  
Jinmann Chon ◽  
Jong Ha Lee ◽  
Junyang Jung ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Bell’S Palsy ◽  
Clinical Prediction ◽  
Bell's Palsy

Idiopathic facial (Bell's) palsy: a clinical survey of prognostic factors

1988 ◽  
Vol 13 (1) ◽  
pp. 17-23 ◽  
Author(s):  
I. M. Smith ◽  
J. P. Heath ◽  
J. A. M. Murray ◽  
R. E. Cull
Keyword(s):  
Prognostic Factors ◽  
Bell’S Palsy ◽  
Bell's Palsy ◽  
Clinical Survey

Prognostic Factors Associated With Recovery in Children With Bell’s Palsy

2019 ◽  
Vol 34 (14) ◽  
pp. 891-896 ◽  
Author(s):  
Elif Karatoprak ◽  
Sila Yilmaz
Keyword(s):  
Prognostic Factors ◽  
Facial Nerve ◽  
Bell’S Palsy ◽  
Steroid Treatment ◽  
Grading System ◽  
Bell's Palsy ◽  
Early Recovery ◽  
Laboratory Findings ◽  
Distribution Width ◽  
Factors Affecting

Objectives: The aim of the study was to determine the prognosis of children with Bell’s palsy and analyze the prognostic factors affecting early recovery. Methods: The records of children with a diagnosis of Bell’s palsy were retrospectively analyzed. Demographic and clinical features including age, gender, House-Brackmann Facial Nerve Grading System House-Brackmann Grading Scale (HBGS) grade at admission and follow-up, and the dosage and onset of steroid treatment were reviewed. Laboratory findings such as red blood cell distribution width and neutrophil-to-lymphocyte ratio were noted. The patients who were recovered within the first month (early recovery) were compared with the patients who were recovered after first month (late recovery) in terms of demographic, clinical characteristics, laboratory findings and treatment modalities in order to determine the risk factors affecting early recovery. Results: A total of 102 children (65 girls and 37 boys) with a mean age of 10.37 ± 4.2 years were included in the study. The complete recovery was detected in 101 children (%99) with Bell’s palsy. Statistically significant difference was found in terms of dosage and time of onset of steroid treatment ( P = .04, P = .035, respectively) and House-Brackmann Facial Nerve Grading System grade on the 10th day ( P = .001) between the early and late recovery groups. Conclusion: The prognosis of Bell’s palsy in children was very good. The prognostic factors affecting the early recovery were being House-Brackmann Facial Nerve Grading System grade 2 or 3 on the 10th day and receiving steroid treatment in the first 24 hours. Neutrophil-to-lymphocyte ratio and red blood cell distribution width were not found to be predictive factors for early recovery.

scholarly journals Predictive Values of Neutrophil-to-Lymphocyte Ratio, Platelet-to-Lymphocyte Ratio, and Other Prognostic Factors in Pediatric Patients With Bell’s Palsy

2020 ◽  
pp. 014556132092209 ◽  
Author(s):  
Dong Hyun Kim ◽  
Jae Hwan Oh ◽  
Junsuk Kim ◽  
Chang Hyun Cho ◽  
Ju Hyoung Lee
Keyword(s):  
Prognostic Factors ◽  
Pediatric Patients ◽  
Bell’S Palsy ◽  
Neutrophil To Lymphocyte Ratio ◽  
Control Group ◽  
Low Grade ◽  
High Grade ◽  
Bell's Palsy ◽  
Platelet To Lymphocyte Ratio ◽  
Lymphocyte Ratio

Background and Objectives: Bell’s palsy (BP) is the most frequent cause of unilateral facial paralysis, and inflammation is believed to play an important role in pathogenesis. Due to its rarity, however, no consensus has been reached regarding optimum treatment or factors affecting prognosis. In the present study, treatment outcomes and prognostic factors of BP were investigated in pediatric patients who underwent steroid therapy. The goal was to investigate the relationship between BP and inflammation using multiple inflammatory markers, including neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), mean platelet volume (MPV), and red cell distribution width (RDW). Materials and Methods: In all, 54 patients diagnosed with BP and 39 healthy randomly selected controls were enrolled in this retrospective study. Demographic characteristics and complete blood cell count test results were compared. In addition, prognostic factors were sought by dividing the 54 patients with BP into 2 groups according to the House-Brackmann grading system: low grade BP (grades II and III) and high grade BP (grades IV and V). Serum samples were analyzed retrospectively on initial presentation and 6 months after the symptom begins. Meaningful hematological parameters include NLR, PLR, MPV, and RDW. Results: The NLR values in the BP group were significantly higher than in the control group. The NLR value in the 2 groups of patients with BP differed significantly. The mean PLR value in the BP group was higher than in the control group; however, there were no significant differences between the low-grade and high-grade BP groups nor were there any statically significant differences in the other characteristics. Conclusion: The NLR and PLR values are readily accessible parameters that may be useful prognostic markers in pediatric patients with BP. Further studies are required to confirm these results and their utility in predicting prognosis and treating pediatric patients with BP.

Electroneurographic facial muscle pattern in Bell's palsy

2000 ◽  
Vol 122 (2) ◽  
pp. 290-297 ◽  
Author(s):  
Mats Engström ◽  
Lars Jonsson ◽  
Margareta Grindlund ◽  
Erik Stälberg
Keyword(s):  
Bell’S Palsy ◽  
Favorable Outcome ◽  
Facial Muscle ◽  
Bell's Palsy ◽  
Prognostic Information ◽  
Facial Region ◽  
Recovery Pattern ◽  
Muscle Region ◽  
Over Time

To study the electroneurographic facial muscle pattern in Bell's palsy over time, electroneurographic recordings in the frontalis, orbicularis oculi, nasalis, and mentalis muscle regions were performed early (mean, day 11) and 1 and 3 months after the onset of the condition in 30 consecutive patients. The correlation between facial muscle electroneurographic recordings over time was also calculated. An additional aim was to assess whether further prognostic information could be obtained by electroneurographic recordings in more than one facial region. The recovery pattern was similar in all 4 facial regions. Initially, the correlation between the facial recordings was weak ( r = 0.20–0.27), but it was improved at follow-up examinations ( r = 0.33–0.65). Favorable outcome in 23 of 24 patients (96%) could have been predicted by the initial nasalis and/or mentalis recordings. The gap between patients with favorable outcome and patients with unfavorable outcome increased when the average electroneurography values were calculated from 1, 2, and 4 muscle recordings (4%, 8%, and 15%, respectively). Our results indicate that in Bell's palsy, electroneurographic examination of more than one facial muscle region may add prognostic information and that the degree of degeneration is initially different in the nerve branches.

scholarly journals Prognostic factors for recovery in Portuguese patients with Bell’s palsy

2016 ◽  
Vol 38 (10) ◽  
pp. 851-856 ◽  
Author(s):  
Margarida Ferreira ◽  
João Firmino-Machado ◽  
Elisa A. Marques ◽  
Paula C. Santos ◽  
Ana Daniela Simões ◽  
...  
Keyword(s):  
Prognostic Factors ◽  
Bell’S Palsy ◽  
Bell's Palsy

scholarly journals Preoperative ALBI grade predicts the outcomes in non-B non-C HCC patients undergoing primary curative resection

2021 ◽  
Author(s):  
Yu-Chieh Tsai ◽  
Fai-Meng Sou ◽  
Yueh-Wei Liu ◽  
Chee-Chien Yong ◽  
Pao-Yuan Huang ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Chronic Hepatitis ◽  
Prognostic Factors ◽  
Curative Resection ◽  
Chang Gung Memorial Hospital ◽  
Exclusion Criteria ◽  
Poor Overall Survival ◽  
Tumor Number ◽  
Tumor Stages ◽  
Grade Ii

Abstract Background The albumin-bilirubin (ALBI) grade has been validated as a significant predictor for hepatocellular carcinoma (HCC). However, there is little information about the ALBI grade in patients with non-B non-C HCC (NBNC-HCC) receiving surgery. Aim This study aimed to evaluate ALBI grade as a prognostic factor in patients with NBNC-HCC after primary curative resection. Method This retrospective study enrolled 2137 HCC patients, who received HCC resection between January 2001 and April 2016 at Kaohsiung Chang Gung Memorial Hospital. With exclusion criteria of patients who had chronic hepatitis B or chronic hepatitis C, and prior HCC treatment before resection and received liver transplantation and BCLC stage B or C, finally we enrolled 168 NBNC-HCC patients who received primary curative resection. ALBI score used for grading as well as clinic opathologic features was analyzed, the formula of ALBI score was log10 [albumin (mg/dL) x 17.1] x 0.66 – albumin (g/dL) x 0.85. Result There were 66 (39.3%), 98 (58.3%), and 4 (2.4%) patients who were stratified into ALBI grade I, II, and III, respectively. Patients with ALBI grade II/III had older age (p = 0.002), hypoalbuminemia (p <0.001), and Child Pugh B (p = 0.009), they also had poor overall survival compared with those with ALBI grade I (p = 0.003). The patients without liver cirrhosis had better survival rate in ALBI grade 1 group (P = 4 0.012). In multivariate analysis, tumor number (p = 0.001) and tumor stages (pTNM stages) (p = 0.007) were independent prognostic factors for recurrence. In predictors for mortality, AFP (p = 0.004), ALBI grade (p = 0.004), tumor number (P=0.003) and tumor stages (pTNM stages) (p <0.001) were independent prognostic factors. Conclusion Preoperative ALBI grade can be used to predict the mortality in patients with NBNC-HCC after primary curative resection.

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