scholarly journals Epidemiology of Candidemia in Kuwait: A Nationwide, Population-Based Study

2021 ◽  
Vol 7 (8) ◽  
pp. 673
Author(s):  
Khaled Alobaid ◽  
Suhail Ahmad ◽  
Mohammad Asadzadeh ◽  
Eiman Mokaddas ◽  
Noura Al-Sweih ◽  
...  
Keyword(s):  
Intensive Care ◽  
Susceptibility Testing ◽  
Fungal Infections ◽  
Population Based ◽  
Allocation Of Resources ◽  
Mixed Species ◽  
Candida Spp ◽  
Population Based Study ◽  
Fluconazole Resistance ◽  
Tof Ms

The Candida species cause a majority of invasive fungal infections. In this article, we describe the nationwide epidemiology of candidemia in Kuwait in 2018. Yeast bloodstream isolates submitted from all major hospitals and identified by phenotypic MALDI-TOF MS and/or by molecular methods were studied. Susceptibility testing was performed by Etest. Out of 313 bloodstream yeasts, 239 Candida spp. isolates (excluding duplicate isolates) were obtained during 234 candidemic episodes among 223 patients. Mixed-species candidemia and re-infection occurred in 5 and 11 patients, respectively. C. albicans (n = 74), C. parapsilosis (n = 54), C. tropicalis (n = 35), C. auris (n = 33), C. glabrata (n = 32), other Candida spp. (n = 11), and other yeasts (n = 9) caused fungemia. Nearly 50% of patients were in intensive care units. Candida spp. isolates (except C. glabrata) were susceptible to caspofungin and 27% of C. auris were amphotericin B-resistant. Resistance to fluconazole was 100% in C. auris, 17% in C. parapsilosis, 12% in C. glabrata, and 1% in C. albicans. Mortality was 47% for other Candida/yeast infections. Nationwide candidemia incidence in 2018 was 5.29 cases/100,000 inhabitants. Changes in species spectrum, increasing fluconazole resistance in C. parapsilosis, and the emergence of C. auris as a major pathogen in Kuwait are noteworthy findings. The data could be of help in informing decisions regarding planning, in the allocation of resources, and in antimicrobial stewardship.

Admission of Term Infants to Neonatal Intensive Care: A Population-Based Study

Birth ◽  
2007 ◽  
Vol 34 (4) ◽  
pp. 301-307 ◽  
Author(s):  
Sally K. Tracy ◽  
Mark B. Tracy ◽  
Elizabeth Sullivan
Keyword(s):  
Intensive Care ◽  
Neonatal Intensive Care ◽  
Population Based ◽  
Term Infants ◽  
Population Based Study

A population-based study on epidemiology of intensive care unit treated traumatic brain injury in Iceland

2017 ◽  
Vol 61 (4) ◽  
pp. 408-417 ◽  
Author(s):  
G. M. Jonsdottir ◽  
S. H. Lund ◽  
B. Snorradottir ◽  
S. Karason ◽  
I. H. Olafsson ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Traumatic Brain Injury ◽  
Intensive Care ◽  
Brain Injury ◽  
Population Based ◽  
Population Based Study

Age Related Changes In Intensive Care Bed Utilization Over Time: A Population Based Study

2010 ◽  
Author(s):  
Kendiss Olafson ◽  
Clare D. Ramsey ◽  
Marina Yogendran ◽  
Jason Waechter ◽  
Randy Fransoo ◽  
...  
Keyword(s):  
Intensive Care ◽  
Population Based ◽  
Population Based Study ◽  
Age Related ◽  
Over Time ◽  
Age Related Changes

How does lack of insurance affect use of intensive care? A population-based study*

2006 ◽  
Vol 34 (8) ◽  
pp. 2043-2048 ◽  
Author(s):  
Marion Danis ◽  
Walter T. Linde-Zwirble ◽  
Avraham Astor ◽  
Jeffrey R. Lidicker ◽  
Derek C. Angus
Keyword(s):  
Intensive Care ◽  
Population Based ◽  
Population Based Study

scholarly journals The epidemiology of pituitary adenomas in Iceland, 1955–2012: a nationwide population-based study

2015 ◽  
Vol 173 (5) ◽  
pp. 655-664 ◽  
Author(s):  
Tomas Thor Agustsson ◽  
Tinna Baldvinsdottir ◽  
Jon G Jonasson ◽  
Elinborg Olafsdottir ◽  
Valgerdur Steinthorsdottir ◽  
...  
Keyword(s):  
Pituitary Adenomas ◽  
Incidental Findings ◽  
Disease Burden ◽  
Clinical Information ◽  
Population Based ◽  
Incidence Rates ◽  
Allocation Of Resources ◽  
Population Based Study ◽  
Total Prevalence ◽  
Clinically Significant

ObjectivePituitary adenomas (PA) are among the most common human neoplasms. To describe the epidemiology and assess the disease burden of clinically significant PAs, population-based studies are needed. Iceland has a small well-defined population. The aim of this study is to describe the epidemiology of PAs in Iceland over an expanded period of time.DesignThis is a retrospective observational study, including all PAs diagnosed in Iceland from 1955 to 2012.MethodsExtensive clinical information was gathered in a database. Prevalence rates for all PA subtypes were calculated along with standardized incidence rates (SIR). Sex ratios and relationships with adenoma size, age, and symptoms were assessed.ResultsWe identified 471 individuals: 190 men and 281 women. Total prevalence in 2012 was 115.57/100 000, prolactinomas were most prevalent (54.37/100 000) followed by non-functioning adenomas (NFPAs) (42.32/100 000). Throughout the period, NFPAs were most common (43.0%) followed by prolactinomas (39.9%) and 11.3% had acromegaly and 5.7% Cushing's disease. Women are diagnosed younger with smaller adenomas. Total SIR has increased significantly and is now 5.8/100 000 per year.ConclusionIn this nationwide study spanning six decades, we have confirmed PAs rising prevalence and incidence rates noted in recent studies. We demonstrated higher overall prevalence and incidence rates than ever previously recorded with an increasing predominance of NFPAs, which is not explained by incidental findings alone. There is a relationship with the introduction of imaging modalities, but the vast majority of patients are symptomatic at diagnosis. This underlines the importance of increased awareness, education, and appropriate allocation of resources for this growing group of patients.

Severe sepsis and septic shock: a prospective population-based study in Icelandic intensive care units

2011 ◽  
Vol 55 (6) ◽  
pp. 722-731 ◽  
Author(s):  
E. VESTEINSDOTTIR ◽  
S. KARASON ◽  
S.E. SIGURDSSON ◽  
M. GOTTFREDSSON ◽  
G.H. SIGURDSSON
Keyword(s):  
Septic Shock ◽  
Severe Sepsis ◽  
Intensive Care ◽  
Intensive Care Units ◽  
Population Based ◽  
Population Based Study ◽  
Sepsis And Septic Shock
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