scholarly journals Basidiobolus omanensis sp. nov. Causing Angioinvasive Abdominal Basidiobolomycosis

2021 ◽  
Vol 7 (8) ◽  
pp. 653
Author(s):  
Abdullah M. S. Al-Hatmi ◽  
Abdullah Balkhair ◽  
Ibrahim Al-Busaidi ◽  
Marcelo Sandoval-Denis ◽  
Saif Al-Housni ◽  
...  

Human infectious fungal diseases are increasing, despite improved hygienic conditions. We present a case of gastrointestinal basidiobolomycosis (GIB) in a 20-year-old male with a history of progressively worsening abdominal pain. The causative agent was identified as a novel Basidiobolus species. Validation of its novelty was established by analysis of the partial ribosomal operon of two isolates from different organs. Phylogeny of ITS and LSU rRNA showed that these isolates belonged to the genus Basidiobolus, positioned closely to B. heterosporus and B. minor. Morphological and physiological data supported the identity of the species, which was named Basidiobolus omanensis, with CBS 146281 as the holotype. The strains showed high minimum inhibitory concentrations (MICs) to fluconazole (>64 µg/mL), itraconazole and voriconazole (>16 µg/mL), anidulafungin and micafungin (>16 µg/mL), but had a low MIC to amphotericin B (1 µg/mL). The pathogenic role of B. omanensis in gastrointestinal disease is discussed. We highlight the crucial role of molecular identification of these rarely encountered opportunistic fungi.

2020 ◽  
Vol 13 (12) ◽  
pp. e236701
Author(s):  
Anitha Gunalan ◽  
Rakhi Biswas ◽  
Balamurugan Sridharan ◽  
Thirthar Palanivelu Elamurugan

Splenic abscess is a rare entity, however if unrecognised or left untreated, it is invariably fatal. We herein report a case of splenic abscess in a 40-year-old man presenting with fever, left-sided abdominal pain, altered sensorium and vomiting. On clinical examination, hepatosplenomegaly was noted and the ultrasound of the abdomen showed multiple hypoechoic regions in the upper pole of spleen, and the diagnosis of splenic abscess was made. The patient received antimicrobial therapy and underwent an open splenectomy with full recovery. Pus aspirated from the splenic abscess grew an unusual organism named Parabacteroides distasonis. In the literature, there are only a few recorded cases of P. distasonis causing splenic abscess. Through this case report, we would like to emphasise the pathogenic role of P. distasonis in causing clinical disease, as this organism is typically known to constitute a part of the normal flora.


This chapter extends the book’s insights about nature, technology, and nation to the larger history of the modern period. While the modern nation loses its grip as a locus of identity and analysis, attempts to understand the operation, disruption, and collapse of continental and global infrastructures continue to mix the natural and the machinic in ways that define them both. Those vulnerabilities emphasize large-scale catastrophe; historiographically, they mask the crucial role of small-scale failures in the experience and culture of late modernity, including its definition of nature. Historical actors turned the uneven geographical distribution of small-scale failures into a marker of distinctive local natures and an element of regional and national identity. Attending to those failures helps not only situate cold-war technologies in the larger modern history of natural and machinic orders; it helps provincialize the superpowers by casting problematic “other” natures as central and primary.


Author(s):  
Elena A. Schneider

The introduction sketches the contours of the British six-week invasion and eleven-month occupation of Havana in 1762–1763, a major event in the history of the Atlantic world. It describes the framework of the book, “an event history” that relies on multiple, overlapping temporal and spatial frames in order to tie together many different strands of history, historical actors, perspectives, and scales. In giving a long-term history of the causes, central dynamics, and enduring consequences of this event, the book focuses on the crucial role of the slave trade and people of African descent. The actions of people of African descent and imperial rivalry over the slave trade shaped both the invasion and occupation of Havana in ways yet to be fully understood. The rest of the book explores the painful irony that black soldiers’ brave service in Havana during the British siege helped lead to new Spanish policies that endorsed and expanded slavery and the slave trade.


2018 ◽  
Vol 31 (4) ◽  
pp. 477-500 ◽  
Author(s):  
Hedvig Gröndal

ArgumentThis article examines how antimicrobial resistance (AMR) came to be constituted as a matter of public concern in Sweden in conjunction with the development of an inter-professional organization called Strama, founded to promote rational prescription of antibiotics. An outbreak of penicillin-resistant pneumococci in the mid-1990s was crucial for this development, because it brought attention to AMR as an urgent public threat. This outbreak fuelled the constitution of AMR as caused by consumption of antibiotics and as a matter of disease control. As a consequence, Strama was able to mobilize the Swedish health officers responsible for disease control. The outbreak is conceptualized as a “transformative event” – an event that makes an issue and its associated risks concrete and urgent. Transformative events play the crucial role of expediting the transformation of issues into matters of public concern.


Metabolites ◽  
2020 ◽  
Vol 10 (10) ◽  
pp. 387
Author(s):  
Valeria Calcaterra ◽  
Angela Zanfardino ◽  
Gian Vincenzo Zuccotti ◽  
Dario Iafusco

Maturity-onset diabetes of the young (MODY) represents a heterogenous group of monogenic autosomal dominant diseases, which accounts for 1–2% of all diabetes cases. Pregnancy represents a crucial time to diagnose MODY forms due to the 50% risk of inheritance in offspring of affected subjects and the potential implications on adequate fetal weight. Not only a history of maternal diabetes may affect the birth weight of offspring, paternal diabetes should also be taken into consideration for a correct pathogenetic diagnosis. The crucial role of maternal and paternal diabetes inheritance patterns and the impact of this inherited mutation on birthweight and the MODY diagnosis was discussed.


2021 ◽  
Vol 12 ◽  
Author(s):  
Pia Tohme ◽  
Martin Kolev

Bifocal attention has been conceptualized differently by various scholars; however, all converge in the idea that the therapeutic process includes the need for the therapist to focus his attention on more than one aspect of the therapeutic setting. We propose a novel view in the application of bifocal attention within the mentalizing framework (MBT) of working with children, adolescents, and their families. We start by providing a short history of the evolution of the construct of bifocal attention, followed by a brief description of the structure of MBT for children and adolescents, emphasizing the crucial role of bifocal and multiple attentions in the mentalizing therapist. We close by discussing the importance of continued supervision in facilitating the maintaining of mentalizing glasses in therapy.


Author(s):  
Lauren Allen Wendling

This article discusses faculty engaged teaching and research as an imperative function of the academic institution in the 21st century.  Reflecting on Ernest Boyer’s Scholarship Reconsidered, this article traces the history of the public nature of higher education and its role within institutions today and discusses the crucial role of promotion and tenure in advancing the engaged work of faculty.


2019 ◽  
Vol 6 (10) ◽  
pp. 3507
Author(s):  
Mena Zarif Helmy ◽  
Ahmed Abdel Kahaar Aldardeer

Background: Laparoscopy has been a valuable technique in the treatment of acute abdominal diseases and can be considered either to diagnose or to treat selected cases.Methods: Here, we randomly select patients with acute abdominal pain in whom the diagnosis was not clear after ultrasonography and plain X-ray, we did diagnostic laparoscopy and according to its findings, we proceeded to surgical intervention. 50 cases with acute abdomen were included in this study in order to clarify the role of laparoscopy in the diagnosis and treatment of acute abdomen.Results: From the 50 patients, the main complaint was abdominal pain and presented in (100%) of patients, 38 of patients had vomiting, fever in 29 patients and 14 patients had abdominal distension, 7 patients had alteration in bowel habits and burning micturition in 6 patients. In this study, 10 patients had past history of previous surgery. By laparoscopy we could see the pathology in 46 patients and complete the management in all of patients but failed to reach the diagnosis in 2 cases and conversion to laparotomy in other 2 cases. Laparoscopic surgery mean was 47.9±12.4 minutes. Hospital stay mean was (1.851) days. Morbidity was 10%. No mortality was found in our study.Conclusions: Laparoscopy can be considered safe for diagnosis and effective in the treatment of patients with acute abdomen. It may be useful to avoid the unnecessary laparotomies in a large number of patients presented with acute abdominal pain.


Res Publica ◽  
1994 ◽  
Vol 36 (2) ◽  
pp. 179-218
Author(s):  
Pasal Delfosse

This article is related with the linguistic conflict in Belgium and the role of the parties and parties factions in the Parliament during the period 1873-1914.  As a contribution to the history of the belgian Parliament, it illustrates the way the flemish claims for more autonomy were transformed in complex agreements in which non-linguistic matters, related to the system of cleavages of the belgian society, somestimes played a crucial role.


1970 ◽  
Vol 12 (3) ◽  
Author(s):  
John Martin

In late 1981 I attended the NZ Historical Association's annual conference at Victoria University, and heard a paper given by Jim Holt on the arbitration system in the early years of the 20th century. At the time I was beginning to work my way into the subject of labour history and the crucial role of arbitration, by looking at rural trade unions in particular. I found Jim Holt's paper particularly interesting and remember discussing with him briefly afterwards the extent to which awards were a means of disciplining and controlling workers such as shearers and threshing-mill hands. It is especially pleasing to see that work and his other already published articles coming together in book form at long last I subsequently sent him a paper of my own which he commented on in a letter saying: 'I haven't spent much time on rural workers partly because the most critical episode for the history of arbitration was well covered by Brendan Thompson (in his thesis on the Canterbury Agricultural and Pastoral Labourers' application for an award in 1907-8)." He also suggested that he was pushing forward his research on the arbitration system: "The 1930s I haven't thought about much yet but I am getting there gradually. Am about to work on the 1920s." I found his open and responsive approach welcome indeed.


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