scholarly journals A One Health Perspective to Recognize Fusarium as Important in Clinical Practice

2020 ◽  
Vol 6 (4) ◽  
pp. 235
Author(s):  
Valeri Sáenz ◽  
Carlos Alvarez-Moreno ◽  
Patrice Le Pape ◽  
Silvia Restrepo ◽  
Josep Guarro ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Interdisciplinary Research ◽  
One Health ◽  
Resistance Mechanisms ◽  
Potential Health ◽  
Hospital Environments ◽  
Plumbing Systems ◽  
Health Related ◽  
Human Infections

Any strategy that proposes solutions to health-related problems recognizes that people, animals, and the environment are interconnected. Fusarium is an example of this interaction because it is capable of infecting plants, animals, and humans. This review provides information on various aspects of these relations and proposes how to approach fusariosis with a One Health methodology (a multidisciplinary, and multisectoral approach that can address urgent, ongoing, or potential health threats to humans, animals, and the environment). Here, we give a framework to understand infection pathogenesis, through the epidemiological triad, and explain how the broad utilization of fungicides in agriculture may play a role in the treatment of human fusariosis. We assess how plumbing systems and hospital environments might play a role as a reservoir for animal and human infections. We explain the role of antifungal resistance mechanisms in both humans and agriculture. Our review emphasizes the importance of developing interdisciplinary research studies where aquatic animals, plants, and human disease interactions can be explored through coordination and collaborative actions.

scholarly journals A One Health Perspective to Recognize Fusarium and Neocosmospora as Important in Clinical Practice

2020 ◽  
Author(s):  
Valeri Sáenz ◽  
Carlos Alvarez-Moreno ◽  
Patrice Le Pape ◽  
Silvia Restrepo ◽  
Josep Guarro ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Human Disease ◽  
One Health ◽  
Resistance Mechanism ◽  
Aquatic Animals ◽  
Hospital Environments ◽  
Plumbing Systems ◽  
Health Related ◽  
Human Infections

A strategy to propose solutions to health-related problems recognizes that people, animals, and the environment are interconnected. Fusarium and Neocosmospora are an example of this interaction due to the capable of infecting plants, animals, and human. This review provides information on various aspects of these relations and proposes how to approach fusariosis with a One Health methodology. Here we give a framework to understand infection pathogenesis, through the epidemiological triad and explain how the broad utilization of fungicides in agriculture may play a role in the treatment of human fusariosis. We assess how plumbing systems and hospital environments might play a role as a reservoir for animal and human infections. We explain the role of antifungal resistance mechanism in both humans and agriculture. Our review emphasizes the importance of developing interdisciplinarity research studies where aquatic animals, plants, and human disease interactions can be explored through coordination and collaborative actions.

scholarly journals Effects of Padel Competition on Brain Health-Related Myokines

2021 ◽  
Vol 18 (11) ◽  
pp. 6042
Author(s):  
Francisco Pradas ◽  
María Pía Cádiz ◽  
María Teresa Nestares ◽  
Inmaculada C. Martínez-Díaz ◽  
Luis Carrasco
Keyword(s):  
Brain Health ◽  
Potential Health ◽  
Positive Effects ◽  
Brain Functions ◽  
Before And After ◽  
Health Related ◽  
Playing Time ◽  
Exercise Induced ◽  
The Brain

Padel is becoming one of the most widespread racket sports that may have potential health benefits. Considering that several myokines mediate the cross-talk between skeletal muscles and the brain, exerting positive effects on brain health status, this study was designed to evaluate the responses of brain-derived neurotrophic factor (BDNF), leukemia inhibitory factor (LIF), and irisin (IR) to padel competition in trained players and to determine whether these responses were sex-dependent. Twenty-four trained padel players (14 women and 10 men with a mean age of 27.8 ± 6.3 years) participated voluntarily in this study. Circulating levels of BDNF, LIF, and IR were assessed before and after simulated padel competition (real playing time, 27.8 ± 8.49 min; relative intensity, 75.2 ± 7.9% maximum heart rate). Except for BDNF responses observed in female players (increasing from 1531.12 ± 269.09 to 1768.56 ± 410.75 ng/mL), no significant changes in LIF and IR concentrations were reported after padel competition. In addition, no sex-related differences were found. Moreover, significant associations between IR and BDNF were established at both pre- and post-competition. Our results suggest that while competitive padel practice stimulates BDNF response in female players, padel competition failed to boost the release of LIF and IR. Future studies are needed to further explore the role of these exercise-induced myokines in the regulation of brain functions and to identify the field sports that can contribute to myokine-mediated muscle–brain crosstalk.

scholarly journals Hard Boiled: Alcohol Use as a Risk Factor for MDMA-Induced Hyperthermia: a Systematic Review

2021 ◽  
Author(s):  
Jan van Amsterdam ◽  
Tibor M. Brunt ◽  
Mimi Pierce ◽  
Wim van den Brink
Keyword(s):  
Alcohol Use ◽  
Negative Impact ◽  
Fatal Outcome ◽  
Alcoholic Beverages ◽  
Potential Health ◽  
Ambient Temperatures ◽  
Induced Hyperthermia ◽  
Delayed Initiation ◽  
Health Related

AbstractAlthough MDMA (ecstasy) is a relatively safe recreational drug and is currently considered for therapeutic use for the treatment of posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD), recreational MDMA use occasionally elicits hyperthermia and hyponatremia, sometimes with a fatal outcome. Specific risk factors for both adverse effects are profuse sweating while vigorously dancing under unfavorable conditions such as high ambient temperatures and insufficient fluid suppletion which result in dehydration. Concomitant use of MDMA and alcohol is highly prevalent, but adds to the existing risk, because alcohol facilitates the emergence of MDMA-induced adverse events, like hyperthermia, dehydration, and hyponatremia. Because of potential health-related consequences of concomitant use of MDMA and alcohol, it is important to identify the mechanisms of the interactions between alcohol and MDMA. This review summarizes the main drivers of MDMA-induced hyperthermia, dehydration, and hyponatremia and the role of concomitant alcohol use. It is shown that alcohol use has a profound negative impact by its interaction with most of these drivers, including poikilothermia, exposure to high ambient temperatures, heavy exercise (vigorous dancing), vasoconstriction, dehydration, and delayed initiation of sweating and diuresis. It is concluded that recreational and clinical MDMA-users should refrain from concomitant drinking of alcoholic beverages to reduce the risk for adverse health incidents when using MDMA.

scholarly journals Ethnobiology in One Health

2016 ◽  
Vol 7 (1) ◽  
Author(s):  
Marsha B. Quinlan ◽  
Robert J. Quinlan
Keyword(s):  
Interdisciplinary Research ◽  
One Health ◽  
Life Science ◽  
Cultural Factors ◽  
Health Needs ◽  
Health Concept ◽  
Health Related ◽  
Human Animal ◽  
Multidisciplinary Perspective ◽  
Social And Cultural Factors

The new One Health concept is, essentially, the ethnobiology of health, addressing the interrelation of human, animal and environmental health. Incited by 2003 outbreaks of animal-borne SARS and avian influenza, One Health’s multidisciplinary perspective complements growing international support for interdisciplinary research and health equity. One Health needs researchers able to integrate social and cultural factors into health-related life science questions.

scholarly journals Role of Health Care Professionals in Prevention of Hospital-Acquired Infections Caused By Carbapenemase Resistant Bacteria: Proactive Approach S in General Hospital Ptuj.

2019 ◽  
Vol 3 (2) ◽  
Author(s):  
Skender Veliu ◽  
Dominika Vrbnjak ◽  
Gabrijela Damevska Kaučič ◽  
Jasmina Kröpfl
Keyword(s):  
Health Care ◽  
General Hospital ◽  
Health Care Professionals ◽  
Treatment Options ◽  
Resistance Mechanisms ◽  
Resistant Bacteria ◽  
High Morbidity ◽  
Proactive Approach ◽  
Health Related

Background: Health-related infections represent a very important complication of health care treatment. They are associated with high morbidity, mortality, disability and high costs of treatment, care and rehabilitation. The problem is its rising incidence, mainly as pathogens have developed various antimicrobial resistance mechanisms. Enterobacterias that excrete carbapenemases are a significant problem, especially as the treatment options for infections is increasingly limited. Several guidelines dictate measures to prevent their spread and control at different levels of health care. Implementation of guidelines in practice is not easy, as it requires a lot of knowledge, cooperation, consistency, material, environmental and human resources. The role of health care professionals is indispensable in this field. The aim of the article is to present the role of health care professionals in the prevention of Carbapenem-resistant Enterobacteriaceae (CRE) infections and proactive approach of General hospital Ptuj in preventing and controlling CRE.

The miR-21 potential of serving as a biomarker for liver diseases in clinical practice

2020 ◽  
Vol 48 (5) ◽  
pp. 2295-2305
Author(s):  
Jiawei Zhang ◽  
Dandan Li ◽  
Rui Zhang ◽  
Peng Gao ◽  
Rongxue Peng ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Liver Diseases ◽  
Hepatic Disease ◽  
Noninvasive Detection ◽  
Diagnosis And Prognosis ◽  
Expected Performance ◽  
Potential Biomarker ◽  
Disease Condition ◽  
Complex Regulatory Network

The role of miR-21 in the pathogenesis of various liver diseases, together with the possibility of detecting microRNA in the circulation, makes miR-21 a potential biomarker for noninvasive detection. In this review, we summarize the potential utility of extracellular miR-21 in the clinical management of hepatic disease patients and compared it with the current clinical practice. MiR-21 shows screening and prognostic value for liver cancer. In liver cirrhosis, miR-21 may serve as a biomarker for the differentiating diagnosis and prognosis. MiR-21 is also a potential biomarker for the severity of hepatitis. We elucidate the disease condition under which miR-21 testing can reach the expected performance. Though miR-21 is a key regulator of liver diseases, microRNAs coordinate with each other in the complex regulatory network. As a result, the performance of miR-21 is better when combined with other microRNAs or classical biomarkers under certain clinical circumstances.

Enhancing clinical practice: The role of practice guidelines.

1994 ◽  
Vol 49 (1) ◽  
pp. 30-33 ◽  
Author(s):  
J. Jarrett Clinton ◽  
Kathleen McCormick ◽  
Jacqueline Besteman
Keyword(s):  
Clinical Practice ◽  
Practice Guidelines
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