scholarly journals Chronic Pulmonary Aspergillosis in Patients with Underlying Respiratory Disorders in Cuba—A Pilot Study

2019 ◽  
Vol 5 (1) ◽  
pp. 18 ◽  
Author(s):  
Nathalie Beltrán Rodríguez ◽  
Javier San Juan-Galán ◽  
Carlos Fernández Andreu ◽  
Dulce María Yera ◽  
Miriam Barrios Pita ◽  
...  
Keyword(s):  
Pilot Study ◽  
Close Association ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Igg Antibodies ◽  
Pulmonary Aspergillosis ◽  
Respiratory Condition ◽  
Mortality And Morbidity ◽  
Chronic Pulmonary Aspergillosis ◽  
Clinical Signs And Symptoms

Chronic pulmonary aspergillosis (CPA) is a fungal infection with high mortality and morbidity rates. This disease is caused by several Aspergillus species and affects patients with an underlying respiratory condition. This pilot study aims to recognize CPA among patients with different respiratory diseases. Twenty-one out of 47 patients were classified as CPA based on the examination of clinical signs and symptoms, radiological findings, mycological culture of respiratory samples and analysis of Aspergillus IgG antibodies. There was a close association between high levels of Aspergillus IgG antibodies and the presence of cavities. Although Aspergillus flavus was the predominant species among clinical isolates, the number of isolates was small to reach conclusions on the prevalence of this species as main cause of CPA in Cuba. From the eleven evaluable patients for the treatment with itraconazole (Lozartil®), nine improved their health status while two did not show any recovery. This drug is included in the therapy schemes for aspergillosis in Cuba.

Phasic jaw motor episodes in healthy subjects with or without clinical signs and symptoms of sleep bruxism: a pilot study

2013 ◽  
Vol 18 (1) ◽  
pp. 187-193 ◽  
Author(s):  
Shuichiro Yoshizawa ◽  
Takeshi Suganuma ◽  
Masayuki Takaba ◽  
Yasuhiro Ono ◽  
Takuro Sakai ◽  
...  
Keyword(s):  
Pilot Study ◽  
Healthy Subjects ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Sleep Bruxism ◽  
Clinical Signs And Symptoms

scholarly journals Aspergillus fumigatus spondylodiscitis with bilateral psoas abscess in a renal transplant patient with pulmonary tuberculosis : A rare case report

2015 ◽  
Vol 3 (2) ◽  
pp. 51
Author(s):  
Ravikumar Tv ◽  
Raghvendra Rao ◽  
Amit Grover ◽  
Daksh Gadi
Keyword(s):  
Case Report ◽  
Pulmonary Tuberculosis ◽  
Invasive Aspergillosis ◽  
Aspergillus Fumigatus ◽  
Psoas Abscess ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Rapid Progression ◽  
Mortality And Morbidity ◽  
Clinical Signs And Symptoms

<p><strong>Background:</strong> Aspergillus spondylodiscitis is increasingly described in immune-compromised patients. Its diagnosis is challenging and its delay results in high mortality and morbidity in view of its relative infrequency and the non- specific clinical signs and symptoms.</p><p><strong>Case report:</strong>We report a case of thoracic spondylodiscitis caused by Aspergillus fumigatus in a patient of renal transplantation and with proven pulmonary tuberculosis.</p><p><strong>Conclusion:</strong>We reiterate that transplantist and the treating physician should have high grade of suspicion for the invasive Aspergillosis even when the patient complains of vague non-specific back pain, and aggresively aim to rule out fungal infection. Early surgical debridement and antifungal therapy to be executedto prevent rapid progression of invasive aspergillosis and neurological damage.</p>

DIAGNOSTIC VALUE OF HYPERBILIRUBINEMIA IN ACUTE APPENDICITIS AND APPENDICULAR PERFORATION

2021 ◽  
pp. 1-3
Author(s):  
Baburam Basumatary ◽  
Abhigyan Borkotoky
Keyword(s):  
Acute Appendicitis ◽  
Serum Bilirubin ◽  
Delayed Diagnosis ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Diagnostic Value ◽  
Mortality And Morbidity ◽  
Medical College ◽  
Clinical Signs And Symptoms ◽  
Appendiceal Perforation

Introduction: Misdiagnosis or delayed diagnosis of acute appendicitis may result in perforation and will increase the mortality and morbidity of patients. Serum Bilirubin may be an aid in the diagnosis of appendiceal perforation. Methods: A study was conducted in the Department of Surgery, Assam Medical College, from November 2019 to November 2020. A total of 50 patients with clinical diagnosis of acute appendicitis or appendicular perforation were studied. The serum bilirubin estimation was carried out in all the patients. Result:Serum Bilirubin was elevated in the patients with both acute appendicitis and appendicular perforation. Conclusion: Serum Bilirubin has a predictive potential for the diagnosis of acute appendicitis and appendicular perforation. Patients who present with clinical signs and symptoms of appendicitis and a raised bilirubin level should be identied as having a higher probability of appendicular perforation.

scholarly journals Clinical signs and symptoms of tinnitus in temporomandibular joint disorders: A pilot study comparing patients and non-patients

2013 ◽  
Vol 60 (1) ◽  
Author(s):  
Amisha Kanji ◽  
Katijah Khoza-Shangase
Keyword(s):  
Pilot Study ◽  
High Frequency ◽  
Temporomandibular Disorder ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Temporomandibular Joint Disorders ◽  
Group A ◽  
Clinical Signs And Symptoms ◽  
Group B ◽  
Nose And Throat

Background: Tinnitus is one of the otologic symptoms commonly reported to be associated with temporomandibular disorder (TMD), and questions regarding its nature and cause continue to plague the clinical and research community.Objectives: The current pilot study aimed to investigate the clinical signs and symptoms of presenting tinnitus in a group of individuals with TMD (group A), and compare them with a group with tinnitus but without TMD (group B). Twenty participants were included in the study, 10 from each group.Methods: All participants underwent basic audiological as well as ear, nose and throat (ENT) evaluations to establish group A and group B. For tinnitus assessment, all participants completed a tinnitus survey questionnaire, and their tinnitus was evaluated using tinnitus matching procedures.Results: Findings revealed clinically relevant differences in attributes of tinnitus in patients with and without TMD. Most of the participants in group A matched their tinnitus to a 6 000 Hz tone or noise, at lower intensity levels than participants in group B, although these results were not statistically significant. Participants in group A associated their tinnitus with a single sound whereas some participants in group B associated it with more than one sound. More participants in group B reported the duration of their tinnitus as constant.Conclusions: Tinnitus may occur in patients with TMD, and be of high frequency. This highlights the importance of thorough assessment for patients with tinnitus as this might have implications for diagnosis and management.

scholarly journals Prevalence and Course of IgA and IgG Antibodies against SARS-CoV-2 in Healthcare Workers during the First Wave of the COVID-19 Outbreak in Germany: Interim Results from an Ongoing Observational Cohort Study

Healthcare ◽  
2021 ◽  
Vol 9 (5) ◽  
pp. 498
Author(s):  
Mark Reinwald ◽  
Peter Markus Deckert ◽  
Oliver Ritter ◽  
Henrike Andresen ◽  
Andreas G. Schreyer ◽  
...  
Keyword(s):  
Cohort Study ◽  
Healthcare Workers ◽  
Significant Proportion ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Observational Cohort Study ◽  
Igg Antibodies ◽  
University Hospitals ◽  
Observational Cohort

(1) Background: Healthcare workers (HCWs) are prone to intensified exposure to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in the ongoing pandemic. We prospectively analyzed the prevalence of antibodies against SARS-CoV-2 in HCWs at baseline and follow up with regard to clinical signs and symptoms in two university hospitals in Brandenburg, Germany. (2) Methods: Screening for anti-SARS-CoV-2 IgA and IgG antibodies was offered to HCWs at baseline and follow up two months thereafter in two hospitals of Brandenburg Medical School during the first wave of the COVID-19 pandemic in Germany in an ongoing observational cohort study. Medical history and signs and symptoms were recorded by questionnaires and analyzed. (3) Results: Baseline seroprevalence of anti-SARS-CoV-2 IgA was 11.7% and increased to 15% at follow up, whereas IgG seropositivity was 2.1% at baseline and 2.2% at follow up. The rate of asymptomatic seropositive cases was 39.5%. Symptoms were not associated with general seropositivity for anti-SARS-CoV-2; however, class switch from IgA to IgG was associated with increased symptom burden. (4) Conclusions: The seroprevalence of antibodies against SARS-CoV-2 was low in HCWs but higher compared to population data and increased over time. Screening for antibodies detected a significant proportion of seropositive participants cases without symptoms.

scholarly journals Dementia and Major Neurocognitive Disorders: Some Lessons Learned One Century after the first Alois Alzheimer’s Clinical Notes

Geriatrics ◽  
2021 ◽  
Vol 6 (1) ◽  
pp. 5
Author(s):  
Donatella Rita Petretto ◽  
Gian Pietro Carrogu ◽  
Luca Gaviano ◽  
Lorenzo Pili ◽  
Roberto Pili
Keyword(s):  
Young Woman ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Neurocognitive Disorders ◽  
Lessons Learned ◽  
Alzheimer Dementia ◽  
Clinical Notes ◽  
Alois Alzheimer ◽  
Clinical Signs And Symptoms

Over 100 years ago, Alois Alzheimer presented the clinical signs and symptoms of what has been later called “Alzheimer Dementia” in a young woman whose name was Augustine Deter [...]

scholarly journals Correction to: Levoketoconazole improves clinical signs and symptoms and patient-reported outcomes in patients with Cushing’s syndrome

Pituitary ◽  
2020 ◽  
Author(s):  
Eliza B. Geer ◽  
Roberto Salvatori ◽  
Atanaska Elenkova ◽  
Maria Fleseriu ◽  
Rosario Pivonello ◽  
...  
Keyword(s):  
Cushing’S Syndrome ◽  
Patient Reported Outcomes ◽  
Clinical Signs ◽  
Signs And Symptoms ◽  
Cushing's Syndrome ◽  
Original Version ◽  
Patient Reported ◽  
Author Group ◽  
Clinical Signs And Symptoms

The original version of the article unfortunately contained an error in the first name and the surname of one of the authors in the author group. The last author name was incorrectly published as ‘F. Pecori Giraldi’ and the corrected name is ‘Francesca Pecori Giraldi’ (First name: Francesca; Surname: Pecori Giraldi).

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