scholarly journals Proteomic Analysis of Pathogenic Fungi Reveals Highly Expressed Conserved Cell Wall Proteins

2016 ◽  
Vol 2 (1) ◽  
pp. 6 ◽  
Author(s):  
Jackson Champer ◽  
James Ito ◽  
Karl Clemons ◽  
David Stevens ◽  
Markus Kalkum
Keyword(s):  
Cell Wall ◽  
Proteomic Analysis ◽  
Pathogenic Fungi ◽  
Cell Wall Proteins

scholarly journals Proteomic Analysis ofPhytophthora infestansReveals the Importance of Cell Wall Proteins in Pathogenicity

2017 ◽  
Vol 16 (11) ◽  
pp. 1958-1971 ◽  
Author(s):  
Svante Resjö ◽  
Maja Brus ◽  
Ashfaq Ali ◽  
Harold J. G. Meijer ◽  
Marianne Sandin ◽  
...  
Keyword(s):  
Cell Wall ◽  
Proteomic Analysis ◽  
Cell Wall Proteins

Proteomic analysis reveals a novel set of cell wall proteins in a transformed tobacco cell culture that synthesises secondary walls as determined by biochemical and morphological parameters

Planta ◽  
2001 ◽  
Vol 212 (3) ◽  
pp. 404-415 ◽  
Author(s):  
Kristopher A. Blee ◽  
Edward R. Wheatley ◽  
Victoria A. Bonham ◽  
Geoffrey P. Mitchell ◽  
Duncan Robertson ◽  
...  
Keyword(s):  
Cell Culture ◽  
Cell Wall ◽  
Proteomic Analysis ◽  
Morphological Parameters ◽  
Cell Wall Proteins ◽  
Tobacco Cell ◽  
Tobacco Cell Culture ◽  
Transformed Tobacco

Employing proteomic analysis to compare Paracoccidioides lutzii yeast and mycelium cell wall proteins

2017 ◽  
Vol 1865 (11) ◽  
pp. 1304-1314 ◽  
Author(s):  
Danielle Silva Araújo ◽  
Patrícia de Sousa Lima ◽  
Lilian Cristiane Baeza ◽  
Ana Flávia Alves Parente ◽  
Alexandre Melo Bailão ◽  
...  
Keyword(s):  
Cell Wall ◽  
Proteomic Analysis ◽  
Cell Wall Proteins

scholarly journals Leaf-specific thionins of barley-a novel class of cell wall proteins toxic to plant-pathogenic fungi and possibly involved in the defence mechanism of plants

1988 ◽  
Vol 7 (6) ◽  
pp. 1559-1565 ◽  
Author(s):  
Holger Bohlmann ◽  
Susanne Clausen ◽  
Susanna Behnke ◽  
Henriette Giese ◽  
Claudia Hiller ◽  
...  
Keyword(s):  
Cell Wall ◽  
Pathogenic Fungi ◽  
Plant Pathogenic Fungi ◽  
Cell Wall Proteins ◽  
Defence Mechanism

The Regulatory Function of the Molecular Chaperone Hsp90 in the Cell Wall Integrity of Pathogenic Fungi

2018 ◽  
Vol 16 (1) ◽  
pp. 44-53
Author(s):  
Marina Campos Rocha ◽  
Camilla Alves Santos ◽  
Iran Malavazi
Keyword(s):  
Cell Wall ◽  
Antifungal Therapy ◽  
Molecular Chaperone ◽  
Regulatory Protein ◽  
Pathogenic Fungi ◽  
Antifungal Drugs ◽  
Cell Wall Integrity ◽  
Regulatory Function ◽  
Loss Of Function ◽  
Hsp90 Inhibition

Different signaling cascades including the Cell Wall Integrity (CWI), the High Osmolarity Glycerol (HOG) and the Ca2+/calcineurin pathways control the cell wall biosynthesis and remodeling in fungi. Pathogenic fungi, such as Aspergillus fumigatus and Candida albicans, greatly rely on these signaling circuits to cope with different sources of stress, including the cell wall stress evoked by antifungal drugs and the host’s response during infection. Hsp90 has been proposed as an important regulatory protein and an attractive target for antifungal therapy since it stabilizes major effector proteins that act in the CWI, HOG and Ca2+/calcineurin pathways. Data from the human pathogen C. albicans have provided solid evidence that loss-of-function of Hsp90 impairs the evolution of resistance to azoles and echinocandin drugs. In A. fumigatus, Hsp90 is also required for cell wall integrity maintenance, reinforcing a coordinated function of the CWI pathway and this essential molecular chaperone. In this review, we focus on the current information about how Hsp90 impacts the aforementioned signaling pathways and consequently the homeostasis and maintenance of the cell wall, highlighting this cellular event as a key mechanism underlying antifungal therapy based on Hsp90 inhibition.

scholarly journals Draft Genome Sequence of the Bacterium Gordonia jacobaea , a New Member of the Gordonia Genus

2015 ◽  
Vol 3 (5) ◽  
Author(s):  
G. Jiménez-Galisteo ◽  
T. G. Villa ◽  
T. Vinuesa ◽  
M. Viñas ◽  
A. Domínguez ◽  
...  
Keyword(s):  
Cell Wall ◽  
Genome Sequence ◽  
Draft Genome ◽  
Draft Genome Sequence ◽  
Cell Wall Proteins ◽  
Santiago De Compostela

Gordonia jacobaea was isolated and characterized in the Department of Microbiology, University of Santiago de Compostela, in 2000. Here we present the draft genome sequence of this species, which will improve our understanding of the diversity and the relation of the cell wall proteins of G. jacobaea with other mycolata.

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