scholarly journals Cognitive Aging in the Seattle Longitudinal Study: Within-Person Associations of Primary Mental Abilities with Psychomotor Speed and Cognitive Flexibility

2016 ◽  
Vol 4 (3) ◽  
pp. 12 ◽  
Author(s):  
Gizem Hülür ◽  
Nilam Ram ◽  
Sherry Willis ◽  
K. Schaie ◽  
Denis Gerstorf
2011 ◽  
Vol 47 (4) ◽  
pp. 1026-1041 ◽  
Author(s):  
Denis Gerstorf ◽  
Nilam Ram ◽  
Christiane Hoppmann ◽  
Sherry L. Willis ◽  
K. Warner Schaie

2020 ◽  
Vol 4 (Supplement_1) ◽  
pp. 663-663
Author(s):  
Dorina Cadar ◽  
Celine De Looze ◽  
Christine McGarrigle

Abstract We investigated cardiovascular health, functional disability and leisure activities profiles independently and in relation to cognitive decline and dementia in high and low-medium income countries using data from the English Longitudinal Study of Ageing, Irish Longitudinal Study on Ageing and Brazilian Bambui Cohort Study of Aging. Functional loss among older Brazilians has shown a hierarchical sequence over the 15-year follow-up, with the highest incidence in functional disability reported for dressing, followed by getting out of bed, bathing/showering, walking across a room, using the toilet and eating (de Oliveira). Using the Life’s Simple 7, an ideal cardiovascular health scoring system evaluating the muscular strength, mobility and physiological stress, we showed a reliable prediction of cognitive trajectories in a representative sample of Irish individuals (De Looze). Within the same cohort, we report discrepancies between men and women in functional decline driven by domestic tasks, rather than determining differential cognitive trajectories (McGarrigle). In an English representative sample, we found that participants with an increasing number of functional impairments over almost a decade were more likely to be classified with subsequent dementia compared with those with no impairments and this may imply a more comprehensive ascertainment during the prodromal stage of dementia (Cadar). In contrast, a reduced risk of dementia was found for individuals with higher levels of engagement in cognitively stimulating activities, that may preserve cognitive reserve until later in life (Almeida). Identifying factors that influence cognitive aging and dementia risk in a multifactorial perspective is critical toward developing adequate intervention and treatment.


2004 ◽  
Vol 59 (2) ◽  
pp. P84-P97 ◽  
Author(s):  
P. Rabbitt ◽  
P. Diggle ◽  
F. Holland ◽  
L. McInnes

Nutrients ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 2475
Author(s):  
Sanne Ahles ◽  
Yala R. Stevens ◽  
Peter J. Joris ◽  
David Vauzour ◽  
Jos Adam ◽  
...  

Cognitive decline is associated with lifestyle-related factors such as overweight, blood pressure, and dietary composition. Studies have reported beneficial effects of dietary anthocyanins on cognition in older adults and children. However, the effect of anthocyanin-rich Aronia melanocarpa extract (AME) on cognition is unknown. Therefore, this study aimed to determine the effect of long-term supplementation with AME on cognitive performance, mood, and vascular function in healthy, middle-aged, overweight adults. In a randomized double-blind placebo-controlled parallel study, 101 participants either consumed 90 mg AME, 150 mg AME, or placebo for 24 weeks. The grooved pegboard test, number cross-out test, and Stroop test were performed as measures for psychomotor speed, attention, and cognitive flexibility. Mood was evaluated with a visual analogue scale, serum brain-derived neurotrophic factor (BDNF) was determined, and vascular function was assessed by carotid ultrasounds and blood pressure measurements. AME improved psychomotor speed compared to placebo (90 mg AME: change = −3.37; p = 0.009). Furthermore, 150 mg AME decreased brachial diastolic blood pressure compared to 90 mg AME (change = 2.44; p = 0.011), but not compared to placebo. Attention, cognitive flexibility, BDNF, and other vascular parameters were not affected. In conclusion, AME supplementation showed an indication of beneficial effects on cognitive performance and blood pressure in individuals at risk of cognitive decline.


1995 ◽  
Vol 69 (1) ◽  
pp. 191-203 ◽  
Author(s):  
Ann L. Gruber-Baldini ◽  
K. Warner Schaie ◽  
Sherry L. Willis

2009 ◽  
Vol 32 (5) ◽  
pp. 540-550 ◽  
Author(s):  
Fang Yu ◽  
Lindsay H. Ryan ◽  
K. Warner Schaie ◽  
Sherry L. Willis ◽  
Ann Kolanowski

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