scholarly journals Comparison of Thermal Neutron and Hard X-ray Dark-Field Tomography

2020 ◽  
Vol 7 (1) ◽  
pp. 1
Author(s):  
Alex Gustschin ◽  
Tobias Neuwirth ◽  
Alexander Backs ◽  
Manuel Viermetz ◽  
Nikolai Gustschin ◽  
...  

High visibility (0.56) neutron-based multi-modal imaging with a Talbot–Lau interferometer at a wavelength of 1.6 Å is reported. A tomography scan of a strongly absorbing quartz geode sample was performed with both the neutron and an X-ray grating interferometer (70 kVp) for a quantitative comparison. Small scattering structures embedded in the absorbing silica matrix were well resolved in neutron dark-field CT slices with a spatial resolution of about 300 μm. Beneficial effects, such as monochromaticity and stronger penetration power of the used neutron radiation, helped to avoid the beam hardening-related artificial dark-field signal which was present in the X-ray data. Both dark-field modalities show mostly the same structures; however, some scattering features appear only in the neutron domain. Potential applications of combined X-ray and neutron multi-modal CT enabling one to probe both the nuclear and the electron density-related structural properties are discussed. strongly absorbing samples are now accessible for the dark-field modality by the use of thermal neutrons.

2020 ◽  
Vol 28 (13) ◽  
pp. 19187 ◽  
Author(s):  
Amogha Pandeshwar ◽  
Matias Kagias ◽  
Zhentian Wang ◽  
Marco Stampanoni

2011 ◽  
Vol 110 (10) ◽  
pp. 109902 ◽  
Author(s):  
Michael Chabior ◽  
Tilman Donath ◽  
Christian David ◽  
Manfred Schuster ◽  
Christian Schroer ◽  
...  

2016 ◽  
Vol 43 (6Part1) ◽  
pp. 2774-2779 ◽  
Author(s):  
Georg Pelzer ◽  
Gisela Anton ◽  
Florian Horn ◽  
Jens Rieger ◽  
André Ritter ◽  
...  

2009 ◽  
Vol 105 (10) ◽  
pp. 102006 ◽  
Author(s):  
F. Pfeiffer ◽  
M. Bech ◽  
O. Bunk ◽  
T. Donath ◽  
B. Henrich ◽  
...  

2021 ◽  
Vol 5 (1) ◽  
Author(s):  
Jana Andrejewski ◽  
Fabio De Marco ◽  
Konstantin Willer ◽  
Wolfgang Noichl ◽  
Alex Gustschin ◽  
...  

Abstract Background Grating-based x-ray dark-field and phase-contrast imaging allow extracting information about refraction and small-angle scatter, beyond conventional attenuation. A step towards clinical translation has recently been achieved, allowing further investigation on humans. Methods After the ethics committee approval, we scanned the full body of a human cadaver in anterior-posterior orientation. Six measurements were stitched together to form the whole-body image. All radiographs were taken at a three-grating large-object x-ray dark-field scanner, each lasting about 40 s. Signal intensities of different anatomical regions were assessed. The magnitude of visibility reduction caused by beam hardening instead of small-angle scatter was analysed using different phantom materials. Maximal effective dose was 0.3 mSv for the abdomen. Results Combined attenuation and dark-field radiography are technically possible throughout a whole human body. High signal levels were found in several bony structures, foreign materials, and the lung. Signal levels were 0.25 ± 0.13 (mean ± standard deviation) for the lungs, 0.08 ± 0.06 for the bones, 0.023 ± 0.019 for soft tissue, and 0.30 ± 0.02 for an antibiotic bead chain. We found that phantom materials, which do not produce small-angle scatter, can generate a strong visibility reduction signal. Conclusion We acquired a whole-body x-ray dark-field radiograph of a human body in few minutes with an effective dose in a clinical acceptable range. Our findings suggest that the observed visibility reduction in the bone and metal is dominated by beam hardening and that the true dark-field signal in the lung is therefore much higher than that of the bone.


2011 ◽  
Vol 110 (5) ◽  
pp. 053105 ◽  
Author(s):  
Michael Chabior ◽  
Tilman Donath ◽  
Christian David ◽  
Manfred Schuster ◽  
Christian Schroer ◽  
...  

2008 ◽  
Vol 7 (2) ◽  
pp. 134-137 ◽  
Author(s):  
F. Pfeiffer ◽  
M. Bech ◽  
O. Bunk ◽  
P. Kraft ◽  
E. F. Eikenberry ◽  
...  

2012 ◽  
Vol 1 (1) ◽  
Author(s):  
Martin Bech ◽  
Simone Schleede ◽  
Guillaume Potdevin ◽  
Klaus Achterhold ◽  
Oliver Bunk ◽  
...  

AbstractX-ray phase and dark-field contrast have recently been the source of much attention in the field of X-ray imaging, as they both contribute new imaging signals based on physical principles that differ from conventional X-ray imaging. With a so-called Talbot grating interferometer, both phase-contrast and dark-field images are obtained simultaneously with the conventional attenuation-based X-ray image, providing three complementary image modalities that are intrinsically registered. Whereas the physical contrast mechanisms behind attenuation and phase contrast are well understood, a formalism to describe the dark-field signal is still in progress. In this article, we report on correlative experimental results obtained with a grating interferometer and with small-angle X-ray scattering. Furthermore, we use a proposed model to quantitatively describe the results, which could be of great importance for future clinical and biomedical applications of grating-based X-ray imaging.


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