scholarly journals Automatic Detection and Distinction of Retinal Vessel Bifurcations and Crossings in Colour Fundus Photography

2017 ◽  
Vol 4 (1) ◽  
pp. 4 ◽  
Author(s):  
Harry Pratt ◽  
Bryan Williams ◽  
Jae Ku ◽  
Charles Vas ◽  
Emma McCann ◽  
...  
Keyword(s):  
Automatic Detection ◽  
Retinal Vessel ◽  
Fundus Photography ◽  
Vessel Bifurcations

scholarly journals An Unusual Retinal Vessel Modification in Patients Affected by JIA-Uveitis with a Follow-Up Longer Than 16 Years

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Alessandro Abbouda ◽  
Irene Abicca ◽  
Simone Bruschi ◽  
Federico Ricci ◽  
Gianluca Aloe ◽  
...  
Keyword(s):  
Vascular Inflammation ◽  
Retinal Vessel ◽  
Fundus Photography ◽  
Vessel Lumen ◽  
Vessel Walls ◽  
Clinical Changes ◽  
University Of Rome ◽  
The University ◽  
Sd Oct

Purpose. To report unusual and rare clinical changes of retinal vessel pattern in a series of patients affected by Juvenile Idiopathic Arthritis (JIA) uveitis with a follow-up longer than 16 years. Methods. A series of three patients with JIA-uveitis followed at the University of Rome “Sapienza” from 1998 to 2014 were reported. The retinal vessels were analyzed with fluorescein angiography using Heidelberg Retinal Angiogram-2 (HRA-2; Heidelberg Engineering GmBH, Dossenheim, Germany) and the Topcon TRC-50LX retinal camera (Topcon Europe, The Netherlands). A Spectralis Domain OCT (SD-OCT) (Spectralis Family Heidelberg, Germany) was performed to evaluate vessel anatomy. Results. Fundus photography showed sheathed vessels localized around the optic disc in every case. Angiography revealed a normal physiology of vessel walls and flow; no sheathing or leakage of dye was observed. SD-OCT demonstrated reflective vessel walls. Vessel lumen appeared patent, and the normal “hourglass configuration” was blurred, but identifiable. Conclusions. Vessel modifications observed in long-standing JIA-uveitis are not signs of vascular inflammation and are not associated to hypoperfusion. In these cases, ophthalmologists should avoid further invasive investigation and should consider introducing SD-OCT as a routine method to evaluate the vessel changes during the follow-up.

scholarly journals The association between retinal vessel abnormalities and H-type hypertension

2020 ◽  
Author(s):  
Kuankuan Huang ◽  
Zhixiang Zhang ◽  
Shan Huang ◽  
Yanwen Jia ◽  
Min Zhang ◽  
...  
Keyword(s):  
Multivariate Analysis ◽  
Multivariate Regression ◽  
Independent Risk Factor ◽  
Retinal Vessel ◽  
Plasma Homocysteine ◽  
Fundus Photography ◽  
Retinal Vessels ◽  
Hypertensive Patients ◽  
Retinal Fundus ◽  
The Relationship

Abstract Background: This study aimed to investigate the relationship between H-type hypertension and retinal vessel abnormalities.Methods: Hypertensive patients were retrospectively enrolled in this study. According to plasma homocysteine (HCY), patients were divided into isolated hypertension and H-type hypertension groups. The diameter of retinal vessels and retinopathy were evaluated by retinal fundus photography. The differences of retinal vessel abnormalities between H-type hypertension and isolated hypertension were investigated by univariate and multivariate regression.Results: A total of 191 hypertensive patients were included, of which 86 were with isolated hypertension and 105 with H-type hypertension. The H-type hypertension group had a higher ratio of retinopathy(P=0.004) and higher degree of retinal arteriosclerosis (P=0.005) than the isolated hypertension group. CRAE (107.47±13.99mm vs. 113.49±11.72mm, P=0.002) and AVR (0.55±0.06 vs. 0.58±0.06, P=0.001) were smaller in H-type hypertension group than those in isolated hypertension group. Multivariate analysis showed that after adjusting for age, sex, course of hypertension and diabetes, H-type hypertension was an independent risk factor of retinopathy (OR, 2.259; 95%CI, 1.165—4.378; P=0.016), CRAE (β=-5.669; 95%CI, -9.452—-1.886; P=0.004), and AVR (β=-0.023; 95%CI, -0.039—-0.007; P=0.005).Conclusion: H-type hypertension is closely related to more retinal vessel abnormalities than isolated hypertension. Controlling H-type hypertension may reduce the risk of small vascular damage.

scholarly journals The association between retinal vessel abnormalities and H-type hypertension

2020 ◽  
Author(s):  
Kuankuan Huang ◽  
Zhixiang Zhang ◽  
Shan Huang ◽  
Yanwen Jia ◽  
Min Zhang ◽  
...  
Keyword(s):  
Multivariate Analysis ◽  
Multivariate Regression ◽  
Independent Risk Factor ◽  
Retinal Vessel ◽  
Plasma Homocysteine ◽  
Fundus Photography ◽  
Retinal Vessels ◽  
Hypertensive Patients ◽  
Retinal Fundus ◽  
The Relationship

Abstract Background: This study aimed to investigate the relationship between H-type hypertension and retinal vessel abnormalities. Methods: Hypertensive patients were retrospectively enrolled in this study. According to plasma homocysteine (HCY), patients were divided into isolated hypertension and H-type hypertension groups. The diameter of retinal vessels and retinopathy were evaluated using retinal fundus photography. The differences of retinal vessel abnormalities between H-type hypertension and isolated hypertension were investigated by univariate and multivariate regression. Results: A total of 191 hypertensive patients were included, of which 86 were with isolated hypertension and 105 with H-type hypertension. The H-type hypertension group had a higher ratio of retinopathy(P=0.004) and higher degree of retinal arteriosclerosis (P=0.005) than the isolated hypertension group. CRAE (107.47±13.99mm v 113.49±11.72mm, P=0.002) and AVR (0.55±0.06 v 0.58±0.06, P=0.001) were smaller in H-type hypertension group than those in isolated hypertension group. Multivariate analysis showed that after adjusting for age, sex, course of hypertension and diabetes, H-type hypertension was an independent risk factor of retinopathy(OR, 2.259; 95%CI, 1.165—4.378; P=0.016), CRAE (B=-5.669; 95%CI, -9.452—-1.886; P=0.004), and AVR (B=-0.023; 95%CI,-0.039—-0.007; P=0.005). Conclusion: H-type hypertension is closely related to more retinal vessel abnormalities than isolated hypertension. Controlling H-type hypertension may reduce the risk of small vascular damage.

scholarly journals The association between retinal vessel abnormalities and H-type hypertension

BMC Neurology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Kuankuan Huang ◽  
Zhixiang Zhang ◽  
Shan Huang ◽  
Yanwen Jia ◽  
Min Zhang ◽  
...  
Keyword(s):  
Multivariate Analysis ◽  
Multivariate Regression ◽  
Independent Risk Factor ◽  
Retinal Vessel ◽  
Plasma Homocysteine ◽  
Fundus Photography ◽  
Retinal Vessels ◽  
Hypertensive Patients ◽  
Retinal Fundus ◽  
The Relationship

Abstract Background This study aimed to investigate the relationship between H-type hypertension and retinal vessel abnormalities. Methods Hypertensive patients were retrospectively enrolled in this study. According to plasma homocysteine (HCY), patients were divided into isolated hypertension and H-type hypertension groups. The diameter of retinal vessels and retinopathy were evaluated by retinal fundus photography. The differences of retinal vessel abnormalities between H-type hypertension and isolated hypertension were investigated by univariate and multivariate regression. Results A total of 191 hypertensive patients were included, of which 86 were with isolated hypertension and 105 with H-type hypertension. The H-type hypertension group had a higher ratio of retinopathy(P = 0.004) and higher degree of retinal arteriosclerosis (P = 0.005) than the isolated hypertension group. CRAE (107.47 ± 13.99µ m vs. 113.49 ± 11.72µ m, P = 0.002) and AVR (0.55 ± 0.06 vs. 0.58 ± 0.06, P = 0.001) were smaller in H-type hypertension group than those in isolated hypertension group. Multivariate analysis showed that after adjusting for age, sex, course of hypertension and diabetes, H-type hypertension was an independent risk factor of retinopathy (OR, 2.259; 95%CI, 1.165—4.378; P = 0.016), CRAE (β=-5.669; 95%CI, -9.452—-1.886; P = 0.004), and AVR (β=-0.023; 95%CI, -0.039—-0.007; P = 0.005). Conclusions H-type hypertension is closely related to more retinal vessel abnormalities than isolated hypertension. Controlling H-type hypertension may reduce the risk of small vascular damage.

scholarly journals Semi-automated retinal vessel analysis in nonmydriatic fundus photography

2013 ◽  
Vol 92 (1) ◽  
pp. e42-e49 ◽  
Author(s):  
Alexander Karl-Georg Schuster ◽  
Joachim Ernst Fischer ◽  
Urs Vossmerbaeumer
Keyword(s):  
Retinal Vessel ◽  
Fundus Photography ◽  
Retinal Vessel Analysis

scholarly journals The Association Between Retinal Vessel Abnormalities and H-type Hypertension

2020 ◽  
Author(s):  
Kuankuan Huang ◽  
Wenwei Yun ◽  
Shan Huang ◽  
Yanwen Jia ◽  
Zhixiang Zhang ◽  
...  
Keyword(s):  
Multivariate Analysis ◽  
Risk Factor ◽  
Multivariate Regression ◽  
Retinal Vessel ◽  
Fundus Photography ◽  
Retinal Vessels ◽  
Hypertensive Patients ◽  
Serum Homocysteine ◽  
Retinal Fundus ◽  
The Relationship

Abstract Introduction: This study aimed to investigate the relationship between H-type hypertension and retinal vessel abnormalities. Methods: Hypertensive patients were retrospectively enrolled in this study. According to serum homocysteine (HCY), patients were divided into isolated hypertension and H-type hypertension group. Retinal fundus photography was used to evaluate the diameter of retinal vessels and retinopathy. Univariate and multivariate regression were used to investigate difference of retinal vessel abnormalities between H-type hypertension and isolated hypertension patients. Results: A total of 191 hypertensive patients were included, of which 85 were isolated hypertension and 106 were H-type hypertension. H-type hypertension patients had a higher ratio of retinopathy(P=0.004) and higher degree of retinal arteriosclerosis (P=0.005). CRAE(P=0.002) and AVR(P=0.001) were smaller in H-type hypertension group. Multivariate analysis showed that after adjusting for age, sex, course of hypertension and diabetes, H-type hypertension were still risk factor of retinopathy(OR, 2.259; 95%CI, 1.165—4.378; P=0.016), CRAE (B=-5.669; 95%CI, -9.452—-1.886; P=0.004), and AVR(B=-0.023; 95%CI,-0.039—-0.007; P=0.005). Conclusion: H-type hypertension may aggravate retinal vessel abnormalities compared with isolated hypertension.

Abstract P323: Arterial Stiffness and Retinal Vessel Diameters: The Atherosclerosis Risk in Communities Study - Neurocognitive Study (ARIC-NCS)

Circulation ◽  
2014 ◽  
Vol 129 (suppl_1) ◽  
Author(s):  
Michelle L Snyder ◽  
Barbara E Klein ◽  
Ronald Klein ◽  
A. Richey Sharrett ◽  
Vijay Nambi ◽  
...  
Keyword(s):  
Older Adults ◽  
Arterial Stiffness ◽  
Population Sample ◽  
Retinal Vessel ◽  
Fundus Photography ◽  
Retinal Arteriole ◽  
Negatively Associated ◽  
Microvascular Changes ◽  
Retinal Microvasculature ◽  
Retinal Vessel Diameters

Background: The retinal microvasculature measured non-invasively by fundus photography enables examination of the role of small blood vessels in cerebrovascular disease since changes in retinal vessels may mimic that of cerebral arterioles. The association of arterial stiffness measured by pulse wave velocity (PWV) and retinal vessel diameters in a population sample is unknown, and evaluation of segment-specific PWV and retinal vessel diameters has not been conducted. Objectives: To quantify the cross-sectional association of PWV with retinal vessel diameters in a population of older adults. Methods: We examined data on PWV and retinal photography in 1,538 adults (853 females; mean age 77 years) from the population-based ARIC-NCS after excluding 43 participants with retinal diseases and 46 with missing covariates. Technicians used the Omron VP-1000 plus system following a standardized protocol to measure carotid femoral (cfPWV), brachial-ankle (baPWV), heart-femoral (hfPWV) and femoral-ankle (faPWV) twice and averaged the results. Non-mydriatic retinal fundus photography of both eyes were obtained and digital images were centrally processed with computer software to calculate central retinal arteriolar equivalent (CRAE) and central retinal vein equivalent (CRVE), which reflect diameters of retinal arterioles and venules, respectively. We used data from a randomly selected eye, and if missing, the non-missing eye was used (n=490). The relationship of PWV and CRAE and CRVE was assessed by multivariable linear regression adjusted for age, gender, race, hypertension, diabetes and smoking (current or former vs. never). Results: PWV was not associated with CRAE. The association of faPWV and CRVE was modified by gender. Among males, faPWV (cm/sec) was negatively associated with CRVE (beta= -0.01 μm, 95% confidence interval (CI): -0.02 to -0.006). This pattern was not observed among females. The association of baPWV and CRVE was modified by gender and smoking in which baPWV was only associated with CRVE in male smokers (current and former). Among male smokers, baPWV (cm/sec) was negatively associated with CRVE (beta= -0.002 μm, CI: -0.02 to -0.008). Interactions were robust to additional adjustment for systolic blood pressure, heart rate and body mass index. No association was observed between cfPWV and hfPWV with CRVE. Conclusion: Arterial stiffness was not associated with retinal arteriole diameters in older adults, but peripheral measures of arterial stiffness were associated with retinal venular diameters in males and male smokers. Whether peripheral stiffness plays a role in microvascular changes or has a shared mechanistic pathway with smoking among males requires additional investigation. The different associations of PWV and retinal measures suggest diverse pathogenic processes are involved in macrovascular and microvascular changes preceding end-organ damage.

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