scholarly journals Efficacy of Age-Specific High-Intensity Stretch-Shortening Contractions in Reversing Dynapenia, Sarcopenia, and Loss of Skeletal Muscle Quality

2018 ◽  
Vol 3 (2) ◽  
pp. 36 ◽  
Author(s):  
Brent Baker
Keyword(s):  
Skeletal Muscle ◽  
High Intensity ◽  
Muscle Quality ◽  
Shortening Contractions

scholarly journals EFFECTS OF PUERARIA LOBATA COMBINED WITH HIGH-INTENSITY INTERMITTENT TRAINING ON SKELETAL MUSCLE QUALITY AND GENE EXPRESSION

2021 ◽  
Vol 27 (spe2) ◽  
pp. 50-53
Author(s):  
Yun Zhao ◽  
Mingang Guo
Keyword(s):  
Gene Expression ◽  
Skeletal Muscle ◽  
Solvent Extraction ◽  
High Intensity ◽  
Fixed Bed ◽  
Muscle Quality ◽  
Pueraria Lobata ◽  
Water Solvent ◽  
Intermittent Training ◽  
Muscle Gene

ABSTRACT Extraction of effective components from Pueraria lobata has important value for skeletal muscle quality and gene expression. The improvement effect of traditional high-intensity intermittent training on skeletal muscle has not been obvious, and it is difficult to guarantee the properties of some volatiles. Based on this, this paper analyzes the effect of high-intensity intermittent training on skeletal muscle quality and gene expression in Pueraria lobata. Based on a brief summary of extraction of Pueraria lobata, status of research on the pharmaceutical components of Pueraria lobata was summarized. Different specimens of Pueraria lobata were selected as research objects, and the process of high-intensity intermittent training was designed. High-intensity intermittent training, solvent extraction and water solvent extraction were combined together to design the fixed-bed continuous extraction scheme. According to the influence of Pueraria lobata on skeletal muscle quality, the influence of intermittent training on skeletal muscle quality was analyzed. The extraction results showed that Pueraria lobata combined with high-intensity intermittent training can effectively improve the content of skeletal muscle and ensure the effective expression of skeletal muscle gene.

scholarly journals CT fatty muscle fraction as a new parameter for muscle quality assessment predicts outcome in venovenous extracorporeal membrane oxygenation

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Anton Faron ◽  
Stefan Kreyer ◽  
Alois M. Sprinkart ◽  
Thomas Muders ◽  
Stefan F. Ehrentraut ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Extracorporeal Membrane Oxygenation ◽  
Adverse Outcomes ◽  
Muscle Quality ◽  
Imaging Biomarker ◽  
Survival Prediction ◽  
Multivariable Logistic Regression Model ◽  
Muscle Area ◽  
Membrane Oxygenation ◽  
The Impact

AbstractImpaired skeletal muscle quality is a major risk factor for adverse outcomes in acute respiratory failure. However, conventional methods for skeletal muscle assessment are inapplicable in the critical care setting. This study aimed to determine the prognostic value of computed tomography (CT) fatty muscle fraction (FMF) as a biomarker of muscle quality in patients undergoing extracorporeal membrane oxygenation (ECMO). To calculate FMF, paraspinal skeletal muscle area was obtained from clinical CT and separated into areas of fatty and lean muscle based on densitometric thresholds. The cohort was binarized according to median FMF. Patients with high FMF displayed significantly increased 1-year mortality (72.7% versus 55.8%, P = 0.036) on Kaplan–Meier analysis. A multivariable logistic regression model was built to test the impact of FMF on outcome. FMF was identified as a significant predictor of 1-year mortality (hazard ratio per percent FMF, 1.017 [95% confidence interval, 1.002–1.033]; P = 0.031), independent of anthropometric characteristics, Charlson Comorbidity Index, Simplified Acute Physiology Score, Respiratory Extracorporeal Membrane Oxygenation Survival Prediction Score, and duration of ECMO support. To conclude, FMF predicted 1-year mortality independently of established clinical prognosticators in ECMO patients and may have the potential to become a new muscle quality imaging biomarker, which is available from clinical CT.

Injury to skeletal muscle fibers of mice following lengthening contractions

1985 ◽  
Vol 59 (1) ◽  
pp. 119-126 ◽  
Author(s):  
K. K. McCully ◽  
J. A. Faulkner
Keyword(s):  
Skeletal Muscle ◽  
Isometric Force ◽  
Muscle Fibers ◽  
Lengthening Contractions ◽  
Control Value ◽  
Skeletal Muscle Fibers ◽  
Maximum Isometric Force ◽  
Distal Tendon ◽  
Shortening Contractions

We tested the hypothesis that lengthening contractions result in greater injury to skeletal muscle fibers than isometric or shortening contractions. Mice were anesthetized with pentobarbital sodium and secured to a platform maintained at 37 degrees C. The distal tendon of the extensor digitorum longus muscle was attached to a servomotor. A protocol consisting of isometric, shortening, or lengthening contractions was performed. After the contraction protocol the distal tendon was reattached, incisions were closed, and the mice were allowed to recover. The muscles were removed after 1–30 days, and maximum isometric force (Po) was measured in vitro at 37 degrees C. Three days after isometric and shortening contractions and sham operations, histological appearance was not different from control and Po was 80% of the control value. Three days after lengthening contractions, histological sections showed that 37 +/- 4% of muscle fibers degenerated and Po was 22 +/- 3% of the control value. Muscle regeneration, first seen at 4 days, was nearly complete by 30 days, when Po was 84 +/- 3% of the control value. We conclude that, with the protocol used, lengthening, but not isometric or shortening contractions, caused significant injury to muscle fibers.

Effects of high-intensity intermittent swimming on PGC-1alpha protein expression in rat skeletal muscle

2005 ◽  
Vol 184 (1) ◽  
pp. 59-65 ◽  
Author(s):  
S. Terada ◽  
K. Kawanaka ◽  
M. Goto ◽  
T. Shimokawa ◽  
I. Tabata
Keyword(s):  
Skeletal Muscle ◽  
Protein Expression ◽  
High Intensity ◽  
Rat Skeletal Muscle

scholarly journals Eat like an athlete: insights of sports nutrition science to support active aging in healthy older adults

GeroScience ◽  
2021 ◽  
Author(s):  
Sara Y. Oikawa ◽  
Tristin D. Brisbois ◽  
Luc J. C. van Loon ◽  
Ian Rollo
Keyword(s):  
Skeletal Muscle ◽  
Performance Enhancement ◽  
Protein Supplementation ◽  
Muscle Quality ◽  
Active Aging ◽  
Omega 3 ◽  
Healthy Older Adults ◽  
Increased Risk ◽  
Muscle Health ◽  
Nutritional Strategies

AbstractSkeletal muscle mass losses with age are associated with negative health consequences, including an increased risk of developing metabolic disease and the loss of independence. Athletes adopt numerous nutritional strategies to maximize the benefits of exercise training and enhance recovery in pursuit of improving skeletal muscle quality, mass, or function. Importantly, many of the principles applied to enhance skeletal muscle health in athletes may be applicable to support active aging and prevent sarcopenia in the healthy (non-clinical) aging population. Here, we discuss the anabolic properties of protein supplementation in addition to ingredients that may enhance the anabolic effects of protein (e.g. omega 3 s, creatine, inorganic nitrate) in older persons. We conclude that nutritional strategies used in pursuit of performance enhancement in athletes are often applicable to improve skeletal muscle health in the healthy older population when implemented as part of a healthy active lifestyle. Further research is required to elucidate the mechanisms by which these nutrients may induce favourable changes in skeletal muscle and to determine the appropriate dosing and timing of nutrient intakes to support active aging.

scholarly journals Acute High-Intensity Exercise Impairs Skeletal Muscle Respiratory Capacity

2018 ◽  
Vol 50 (12) ◽  
pp. 2409-2417 ◽  
Author(s):  
GWENAEL LAYEC ◽  
GREGORY M. BLAIN ◽  
MATTHEW J. ROSSMAN ◽  
SONG Y. PARK ◽  
COREY R. HART ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
High Intensity ◽  
High Intensity Exercise ◽  
Respiratory Capacity
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