scholarly journals An Injectable Glass Polyalkenoate Cement Engineered for Fracture Fixation and Stabilization

2017 ◽  
Vol 8 (3) ◽  
pp. 25 ◽  
Author(s):  
Basel Khader ◽  
Sean Peel ◽  
Mark Towler
Keyword(s):  
Fracture Fixation ◽  
Glass Polyalkenoate Cement

scholarly journals An injectable glass polyalkenoate cement engineered for fracture fixation and stabilization

2021 ◽  
Author(s):  
Basel A. Khader ◽  
Sean A. F. Peel ◽  
Mark R. Towler
Keyword(s):  
Mechanical Properties ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Fracture Fixation ◽  
Bovine Serum ◽  
Germanium Oxide ◽  
Setting Times ◽  
Ability To Act ◽  
Keywords Fracture ◽  
Glass Polyalkenoate Cement

Glass polyalkenoate cements (GPCs) have potential as bio-adhesives due to their ease of application, appropriate mechanical properties, radiopacity and chemical adhesion to bone. Aluminium (Al)-free GPCs have been discussed in the literature, but have proven difficult to balance injectability with mechanical integrity. For example, zinc-based, Al-free GPCs reported compressive strengths of 63 MPa, but set in under 2 min. Here, the authors design injectable GPCs (IGPCs) based on zinc-containing, Al-free silicate compositions containing GeO2, substituted for ZnO at 3% increments through the series. The setting reactions, injectability and mechanical properties of these GPCs were evaluated using both a hand-mix (h) technique, using a spatula for sample preparation and application and an injection (i) technique, using a 16-gauge needle, post mixing, for application. GPCs ability to act as a carrier for bovine serum albumin (BSA) was also evaluated. Germanium (Ge) and BSA containing IGPCs were produced and reported to have working times between 26 and 44 min and setting times between 37 and 55 min; the extended handling properties being as a result of less Ge. The incorporation of BSA into the cement had no effect on the handling and mechanical properties, but the latter were found to have increased compression strength with the addition of Ge from between 27 and 37 MPa after 30 days maturation. Keywords: fracture fixation; distal radius fracture; germanium oxide; polyacrylic acid; injectable glass polyalkenoate cements; bovine serum albumin

scholarly journals An injectable glass polyalkenoate cement engineered for fracture fixation and stabilization

2021 ◽  
Author(s):  
Basel A. Khader ◽  
Sean A. F. Peel ◽  
Mark R. Towler
Keyword(s):  
Mechanical Properties ◽  
Bovine Serum Albumin ◽  
Serum Albumin ◽  
Fracture Fixation ◽  
Bovine Serum ◽  
Germanium Oxide ◽  
Setting Times ◽  
Ability To Act ◽  
Keywords Fracture ◽  
Glass Polyalkenoate Cement

Glass polyalkenoate cements (GPCs) have potential as bio-adhesives due to their ease of application, appropriate mechanical properties, radiopacity and chemical adhesion to bone. Aluminium (Al)-free GPCs have been discussed in the literature, but have proven difficult to balance injectability with mechanical integrity. For example, zinc-based, Al-free GPCs reported compressive strengths of 63 MPa, but set in under 2 min. Here, the authors design injectable GPCs (IGPCs) based on zinc-containing, Al-free silicate compositions containing GeO2, substituted for ZnO at 3% increments through the series. The setting reactions, injectability and mechanical properties of these GPCs were evaluated using both a hand-mix (h) technique, using a spatula for sample preparation and application and an injection (i) technique, using a 16-gauge needle, post mixing, for application. GPCs ability to act as a carrier for bovine serum albumin (BSA) was also evaluated. Germanium (Ge) and BSA containing IGPCs were produced and reported to have working times between 26 and 44 min and setting times between 37 and 55 min; the extended handling properties being as a result of less Ge. The incorporation of BSA into the cement had no effect on the handling and mechanical properties, but the latter were found to have increased compression strength with the addition of Ge from between 27 and 37 MPa after 30 days maturation. Keywords: fracture fixation; distal radius fracture; germanium oxide; polyacrylic acid; injectable glass polyalkenoate cements; bovine serum albumin

Biomechanical characteristics of allogeneic cortical bone pins designed for fracture fixation

2008 ◽  
Vol 21 (02) ◽  
pp. 140-146
Author(s):  
M. R. Edwards ◽  
S. P. James ◽  
W. S. Dernell ◽  
R. J. Scott ◽  
A. M. Bachand ◽  
...  
Keyword(s):  
Stainless Steel ◽  
Cortical Bone ◽  
Fracture Fixation ◽  
Impact Testing ◽  
Left Tibia ◽  
Four Point Bending ◽  
And Gender ◽  
The Right ◽  
Biomechanical Comparison ◽  
Better Than

SummaryThe biomechanical characteristics of 1.2 mm diameter allogeneic cortical bone pins harvested from the canine tibia were evaluated and compared to 1.1 mm diameter stainless steel pins and 1.3 mm diameter polydioxanone (PDS) pins using impact testing and four-point bending. The biomechanical performance of allogeneic cortical bone pins using impact testing was uniform with no significant differences between sites, side, and gender. In four-point bending, cortical bone pins harvested from the left tibia (204.8 ± 77.4 N/mm) were significantly stiffer than the right tibia (123.7 ± 54.4 N/mm, P=0.0001). The site of bone pin harvest also had a significant effect on stiffness, but this was dependent on interactions with gender and side. Site C in male dogs had the highest mean stiffness in the left tibia (224.4 ± 40.4 N/mm), but lowest stiffness in the right tibia (84.9 ± 24.2 N/mm). Site A in female dogs had the highest mean stiffness in the left tibia (344.9 ± 117.4 N/mm), but lowest stiffness in the right tibia (60.8 ± 3.7 N/mm). The raw and adjusted bending properties of 1.2 mm cortical bone pins were significantly better than 1.3 mm PDS pins, but significantly worse than 1.1 mm stainless steel pins (P<0.0001). In conclusion, cortical bone pins may be suitable as an implant for fracture fixation based on initial biomechanical comparison to stainless steel and PDS pins used in clinical practice.

scholarly journals Patient Positioning for Proximal Femur Fracture Fixation: a Review of Best Practices

2021 ◽  
Author(s):  
Khushdeep S. Vig ◽  
Curtis Adams ◽  
Joseph R. Young ◽  
Eric Perloff ◽  
Casey M. O’Connor ◽  
...  
Keyword(s):  
Best Practices ◽  
Proximal Femur ◽  
Fracture Fixation ◽  
Femur Fracture ◽  
Patient Positioning ◽  
Proximal Femur Fracture
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