scholarly journals Health-Related Quality of Life in Levothyroxine-Treated Hypothyroid Women and Women without Hypothyroidism: A Case–Control Study

2020 ◽  
Vol 9 (12) ◽  
pp. 3864
Author(s):  
Benjamín Romero-Gómez ◽  
Paula Guerrero-Alonso ◽  
Juan Manuel Carmona-Torres ◽  
Diana P. Pozuelo-Carrascosa ◽  
José Alberto Laredo-Aguilera ◽  
...  

The use of levothyroxine is not always related to the elimination of the symptoms of hypothyroidism. The aim of this study is to compare the health-related quality of life (HRQOL) of a group of hypothyroid women under levothyroxine treatment with that of a group of non-hypothyroid women. Methodology: A case–control study was performed. We used convenience sampling. The case group consisted of 152 levothyroxine-treated hypothyroid women; the control group consisted of 238 women without hypothyroidism disorders. All of the participants were euthyroid according to the clinical practice guidelines. We used as instruments the Short Form-12 questionnaire (SF-12v1) and a sociodemographic questionnaire. Results: Hypothyroid women scored significantly lower in HRQOL in SF-12v1 mental and physical components than the control group (mental component summary: 41.23 ± 12.12 vs. 46.45 ± 10.22, p < 0.001; physical component summary: 49.64 ± 10.16 vs. 54.75 ± 5.76, p < 0.001). body mass index (BMI) and age showed an influence on the physical component (p < 0.001 in both variables). Adjusted for age and BMI, hypothyroidism was still related to worse scores (p < 0.001). Conclusion: Despite being euthyroid, women with hypothyroidism showed a poorer quality of life than women without hypothyroidism. Health professionals need to assess the HRQOL of women with hypothyroidism. Further research on HRQOL and hypothyroidism is needed.

2010 ◽  
Vol 8 (1) ◽  
pp. 121 ◽  
Author(s):  
Channa T Hijmans ◽  
Karin Fijnvandraat ◽  
Jaap Oosterlaan ◽  
Harriët Heijboer ◽  
Marjolein Peters ◽  
...  

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Nerea Fernández de Larrea-Baz ◽  
Beatriz Pérez-Gómez ◽  
Ángel Guerrero-Zotano ◽  
Ana María Casas ◽  
Begoña Bermejo ◽  
...  

2017 ◽  
Vol 225 (4) ◽  
pp. e105
Author(s):  
Gopal L. Narang ◽  
Angela B. Smith ◽  
Byron Jaeger ◽  
Laura Pinheiro ◽  
Lloyd J. Edwards ◽  
...  

Dermatology ◽  
2014 ◽  
Vol 228 (3) ◽  
pp. 261-268 ◽  
Author(s):  
G.R. Vinding ◽  
K.M. Knudsen ◽  
C. Ellervik ◽  
A.B. Olesen ◽  
G.B.E. Jemec

2020 ◽  
Vol 20 (4) ◽  
pp. 829-836 ◽  
Author(s):  
Elizabeth Jedel ◽  
Magnus L. Elfström ◽  
Catharina Hägglin

AbstractObjectivesThe cardinal symptom of burning mouth syndrome (BMS) is long-lasting pain and comprehensive health-related quality of life (HRQL) assessments may estimate how well patients with BMS live in relation to their health issues. The aims of the study were to explore general and BMS-specific HRQL based on an HRQL model and to compare HRQL in patients with BMS and age-matched controls.MethodsFor this case-control study 56 female patients with BMS and 56 female controls completed the following: A general questionnaire with Global items for life satisfaction, general health and oral health; General Population-Clinical Outcomes in Routine Evaluation (GP-CORE); Hospital Anxiety and Depression Scale (HADS); and Oral Health Impact Profile-14 (OHIP-14). Patients with BMS completed additional questionnaires which included BMS-problem severity, a global item for ratings of overall severity perceptions measured by visual analog scale (VAS); and BMS-modified Multidimensional Pain Inventory-Swedish version (MPI-S). BMS-modified MPI-S includes the three subscales Pain severity, Interference and Social support.ResultsPatients with BMS scored worse on all global items, GP-CORE, HADS and OHIP-14 compared to controls and the differences were large. Patients with severe BMS problems, as defined by a median split on BMS-problem severity, scored worse on the BMS-modified MPI-S subscale Pain severity and the difference was large.ConclusionsWe found clearly impaired general HRQL in patients with BMS compared to controls. For specific HRQL, the severity of pain was worse among patients with higher overall BMS-problem severity. The HRQL model with global ratings together with physical, psychological and social concepts has capacity to increase comparability and validity of studies, however further evaluations of the measures are needed.The HRQL model may be used over time to increase the understanding of different HRQL aspects and their internal relationships. In clinical settings, with an increased knowledge of one´s own distinctive quality of life abilities and restrictions, the patients with BMS can be guided and supported to manage their long-lasting pain. The HRQL model may be an aid toward bridging distinctions between general and oral health to further encourage collaboration between medicine and odontology.


Digestion ◽  
2010 ◽  
Vol 82 (4) ◽  
pp. 221-228 ◽  
Author(s):  
Gian Eugenio Tontini ◽  
Emanuele Rondonotti ◽  
Valeria Saladino ◽  
Simone Saibeni ◽  
Roberto de Franchis ◽  
...  

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