scholarly journals 3D Printing Approach in Dentistry: The Future for Personalized Oral Soft Tissue Regeneration

2020 ◽  
Vol 9 (7) ◽  
pp. 2238
Author(s):  
Dobrila Nesic ◽  
Birgit M. Schaefer ◽  
Yue Sun ◽  
Nikola Saulacic ◽  
Irena Sailer
Keyword(s):  
Soft Tissue ◽  
3D Printing ◽  
Tissue Regeneration ◽  
Printing Technology ◽  
3D Printing Technology ◽  
Soft Tissue Regeneration ◽  
Periodontal Tissues ◽  
Surgical Guides ◽  
3D Printed ◽  
Oral Soft Tissue

Three-dimensional (3D) printing technology allows the production of an individualized 3D object based on a material of choice, a specific computer-aided design and precise manufacturing. Developments in digital technology, smart biomaterials and advanced cell culturing, combined with 3D printing, provide promising grounds for patient-tailored treatments. In dentistry, the “digital workflow” comprising intraoral scanning for data acquisition, object design and 3D printing, is already in use for manufacturing of surgical guides, dental models and reconstructions. 3D printing, however, remains un-investigated for oral mucosa/gingiva. This scoping literature review provides an overview of the 3D printing technology and its applications in regenerative medicine to then describe 3D printing in dentistry for the production of surgical guides, educational models and the biological reconstructions of periodontal tissues from laboratory to a clinical case. The biomaterials suitable for oral soft tissues printing are outlined. The current treatments and their limitations for oral soft tissue regeneration are presented, including “off the shelf” products and the blood concentrate (PRF). Finally, tissue engineered gingival equivalents are described as the basis for future 3D-printed oral soft tissue constructs. The existing knowledge exploring different approaches could be applied to produce patient-tailored 3D-printed oral soft tissue graft with an appropriate inner architecture and outer shape, leading to a functional as well as aesthetically satisfying outcome.

scholarly journals Could 3D printing be the future for oral soft tissue regeneration?

Bioprinting ◽  
2020 ◽  
Vol 20 ◽  
pp. e00100 ◽  
Author(s):  
Dobrila Nesic ◽  
Stéphane Durual ◽  
Laurine Marger ◽  
Mustapha Mekki ◽  
Irena Sailer ◽  
...  
Keyword(s):  
Soft Tissue ◽  
3D Printing ◽  
Tissue Regeneration ◽  
Soft Tissue Regeneration ◽  
The Future ◽  
Oral Soft Tissue

scholarly journals A millifluidic chip for cultivation of fish embryos and toxicity testing fabricated by 3D printing technology

RSC Advances ◽  
2021 ◽  
Vol 11 (33) ◽  
pp. 20507-20518
Author(s):  
Petr Panuška ◽  
Zuzana Nejedlá ◽  
Jiří Smejkal ◽  
Petr Aubrecht ◽  
Michaela Liegertová ◽  
...  
Keyword(s):  
3D Printing ◽  
Toxicity Testing ◽  
Toxicity Screening ◽  
Printing Technology ◽  
3D Printing Technology ◽  
Fish Embryos ◽  
3D Printed ◽  
Novel Design

A novel design of 3D printed zebrafish millifluidic system for embryonic long-term cultivation and toxicity screening has been developed. The chip unit provides 24 cultivation chambers and a selective individual embryo removal functionality.

scholarly journals 3D Printing for Soft Tissue Regeneration and Applications in Medicine

Biomedicines ◽  
2021 ◽  
Vol 9 (4) ◽  
pp. 336
Author(s):  
Sven Pantermehl ◽  
Steffen Emmert ◽  
Aenne Foth ◽  
Niels Grabow ◽  
Said Alkildani ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Additive Manufacturing ◽  
Soft Tissue ◽  
3D Printing ◽  
Tissue Regeneration ◽  
Research Area ◽  
Modern Medicine ◽  
Soft Tissue Regeneration ◽  
General Overview

The use of additive manufacturing (AM) technologies is a relatively young research area in modern medicine. This technology offers a fast and effective way of producing implants, tissues, or entire organs individually adapted to the needs of a patient. Today, a large number of different 3D printing technologies with individual application areas are available. This review is intended to provide a general overview of these various printing technologies and their function for medical use. For this purpose, the design and functionality of the different applications are presented and their individual strengths and weaknesses are explained. Where possible, previous studies using the respective technologies in the field of tissue engineering are briefly summarized.

scholarly journals 3D-Printed Nanocellulose-Based Cushioning–Antibacterial Dual-Function Food Packaging Aerogel

Molecules ◽  
2021 ◽  
Vol 26 (12) ◽  
pp. 3543
Author(s):  
Wei Zhou ◽  
Jiawei Fang ◽  
Shuwei Tang ◽  
Zhengguo Wu ◽  
Xiaoying Wang
Keyword(s):  
3D Printing ◽  
Food Packaging ◽  
Fruits And Vegetables ◽  
Antibacterial Effect ◽  
Dual Function ◽  
Printing Technology ◽  
E Coli ◽  
3D Printing Technology ◽  
The Core ◽  
3D Printed

Cushioning and antibacterial packaging are the requirements of the storage and transportation of fruits and vegetables, which are essential for reducing the irreversible quality loss during the process. Herein, the composite of carboxymethyl nanocellulose, glycerin, and acrylamide derivatives acted as the shell and chitosan/AgNPs were immobilized in the core by using coaxial 3D-printing technology. Thus, the 3D-printed cushioning–antibacterial dual-function packaging aerogel with a shell–core structure (CNGA/C–AgNPs) was obtained. The CNGA/C–AgNPs packaging aerogel had good cushioning and resilience performance, and the average compression resilience rate was more than 90%. Although AgNPs was slowly released, CNGA/C–AgNPs packaging aerogel had an obvious antibacterial effect on E. coli and S. aureus. Moreover, the CNGA/C–AgNPs packaging aerogel was biodegradable. Due to the customization capabilities of 3D-printing technology, the prepared packaging aerogel can be adapted to more application scenarios by accurately designing and regulating the microstructure of aerogels, which provides a new idea for the development of food intelligent packaging.

scholarly journals 3D PRINTING PREOPERATIVE PLANNING AND CUSTOMIZED SURGICAL GUIDES ASSOCIATED WITH O-ARM NAVIGATION SYSTEM FOR MULTIPLANAR OSTEOTOMY OF COMPLEX PELVIC DEFORMITY

2021 ◽  
Vol 108 (Supplement_3) ◽  
Author(s):  
M Fernández Álvarez ◽  
C Garcés Zarzalejo ◽  
M Adeba García ◽  
P Pernia Gomez ◽  
J A. Martínez Agüeros ◽  
...  
Keyword(s):  
3D Printing ◽  
Navigation System ◽  
Pelvic Ring ◽  
Posterior Column ◽  
Pubic Ramus ◽  
Printing Technology ◽  
3D Printing Technology ◽  
Ring Model ◽  
Surgical Guides ◽  
Hip Rotation

Abstract INTRODUCTION 3D printing technology is penetrating the healthcare field at an astonishing rate. The reduction of its costs, makes it more accessible to everyone. MATERIAL AND METHODS 35-year-old woman who had functional limitation in her right hip due to pelvic ring fracture in her childhood. She had dysmetria of lower limbs and femoral anteversion of 40 degrees. Imaging tests showed vicious consolidation of the right hemipelvis associated with antero-medial displacement. RESULTS Preoperative, we performed her 3D printing pelvic ring model. Osteotomies were digital planned (iliac crest, superior pubic ramus, incomplete of inferior pubic ramus, and semicircular of posterior column) and also how many degrees we would need for rotation the osteotomized fragment. Posterior column osteotomy was the most difficult, so we designed 3D surgical printing cutting guide able to being inserted into the iliac fossa. We used it to introduced four Kirschnner wires that leads us as a guide to avoid the greater sciatic notch. O-arm navigation system helped us make sure to achieve more precision. 3D printing pelvic ring model was sterilized to pre-contouring osteosynthesis plates. After two years of follow-up, good functional results were observed, without gait claudication either limb dysmetria. Her range of motion is 105 degrees of hip flexion, 20 degrees of internal hip rotation and 40 degrees of external hip rotation. Complete radiological consolidation was observed. CONCLUSION Digital planning and 3D printing technology allows to improve three-dimensional compression of bone pathology leading to a higher likelihood of a predictable ideal outcome compared to conventional techniques.

APPLICATION OF 3D PRINTING TECHNOLOGY FOR RAPID TOOLING IN SHEET METAL FORMING

2020 ◽  
Vol 3 ◽  
pp. 20-30
Author(s):  
M.A. SEREZHKIN ◽  
D.O. KLIMYUK ◽  
A.I. PLOKHIKH
Keyword(s):  
3D Printing ◽  
Sheet Metal ◽  
Sheet Metal Forming ◽  
Metal Forming ◽  
Rapid Tooling ◽  
Printing Technology ◽  
3D Printing Technology ◽  
3D Printed ◽  
Printed Materials ◽  
Printing Parameters

The article presents the study of the application of 3D printing technology for rapid tooling in sheet metal forming for custom or small–lot manufacturing. The main issue of the usage of 3D printing technology for die tooling was discovered. It is proposed to use the method of mathematical modelling to investigate how the printing parameters affect the compressive strength of FDM 3D–printed parts. Using expert research methods, the printing parameters most strongly affecting the strength of products were identified for further experiments. A method for testing the strength of 3D–printed materials has been developed and tested.

scholarly journals Implementation of 3D Printing Technology in the Food Industry

2021 ◽  
pp. 50-54
Author(s):  
Nor Aiman Sukindar ◽  
Noorazizi Mohd Samsuddin ◽  
Sharifah Imihezri Bt. Syed Shaharuddin ◽  
Shafie Kamaruddin ◽  
Ahmad Zahirani Ahmad Azhar ◽  
...  
Keyword(s):  
3D Printing ◽  
New Product Development ◽  
Food Industry ◽  
Printing Technology ◽  
3D Printing Technology ◽  
Fabrication Cost ◽  
Food Packages ◽  
3D Printed ◽  
The Cost ◽  
Fabrication Time

This project involves the implementation of 3D printing technology on designing and fabricating food holders in the food industry. Food holders are designed to hold the food packages in the filling line for food manufacturing industries that apply retort technology. Therefore, this study aims to implement the 3D printing technology in particular FDM to fabricate food holders for the food processing industry. The approach of using this technology is focused on giving more view on the capability of 3D printing technology, aiming at reducing the overall process fabrication cost and fabrication time. Hence, the fabrication cost and time between FDM and conventional machining methods were compared. This study revealed that Organic Gain food industry was able to reduce the cost and fabrication time for the food holder up to approximately 96.3% and 72% respectively. This project gives an insight into the ability of 3D printing technology in delivering the demands of the industry in producing parts as well as the adaptability of the technology to the industry in new product development. The project was carried out successfully and the 3D printed food holder has been tested and functions smoothly.

scholarly journals Promising Applications of Additive-Manufactured (3D-printed) Electrochemical Sensors for Forensic Chemistry

2021 ◽  
Author(s):  
Sílvia Castro ◽  
Raquel Rocha ◽  
Afonso João ◽  
Eduardo Richter ◽  
Rodrigo Munoz
Keyword(s):  
3D Printing ◽  
Illicit Drugs ◽  
Industrial Revolution ◽  
Electrochemical Sensors ◽  
Forensic Chemistry ◽  
Recent Contribution ◽  
Printing Technology ◽  
3D Printing Technology ◽  
Wide Range ◽  
3D Printed

Additive-manufacturing is one of the major pillars of the new industrial revolution and the three-dimensional (3D) printing technology has been highlighted in this scenario. Among the many areas benefited by 3D-printing, the development of electrochemical sensors has appeared in evidence in the last years. One potential application of 3D-printed electrochemical sensors is devoted to forensic chemistry, which demands for portable analytical methods that can provide on-site measurements and thus bring a relevant information in loco. In this context, this review highlights the recent contribution of 3D-printing technology on the development of electrochemical sensors with great promises for on-site analysis in “real-world” forensic scenarios. From the detection of trace explosives, gunshot residues, illicit drugs and chemical threats, to the measurement of adulterants in food and fuels, we show the wide range of applications that 3D-printed electrochemical sensors have been proposed and future demands that can be addressed by such a powerful, affordable, and accessible tool.

3D Printing Technology in Drug Delivery: Recent Progress and Application

2019 ◽  
Vol 24 (42) ◽  
pp. 5039-5048 ◽  
Author(s):  
Sabna Kotta ◽  
Anroop Nair ◽  
Nimer Alsabeelah
Keyword(s):  
Drug Delivery ◽  
3D Printing ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Pharmaceutical Manufacturing ◽  
Layer By Layer ◽  
Printing Technology ◽  
Drug Dosing ◽  
3D Printing Technology ◽  
3D Printed

Background: 3D printing technology is a new chapter in pharmaceutical manufacturing and has gained vast interest in the recent past as it offers significant advantages over traditional pharmaceutical processes. Advances in technologies can lead to the design of suitable 3D printing device capable of producing formulations with intended drug release. Methods: This review summarizes the applications of 3D printing technology in various drug delivery systems. The applications are well arranged in different sections like uses in personalized drug dosing, complex drugrelease profiles, personalized topical treatment devices, novel dosage forms and drug delivery devices and 3D printed polypills. Results: This niche technology seems to be a transformative tool with more flexibility in pharmaceutical manufacturing. Typically, 3D printing is a layer-by-layer process having the ability to fabricate 3D formulations by depositing the product components by digital control. This additive manufacturing process can provide tailored and individualized dosing for treatment of patients different backgrounds with varied customs and metabolism pattern. In addition, this printing technology has the capacity for dispensing low volumes with accuracy along with accurate spatial control for customized drug delivery. After the FDA approval of first 3D printed tablet Spritam, the 3D printing technology is extensively explored in the arena of drug delivery. Conclusion: There is enormous scope for this promising technology in designing various delivery systems and provides customized patient-compatible formulations with polypills. The future of this technology will rely on its prospective to provide 3D printing systems capable of manufacturing personalized doses. In nutshell, the 3D approach is likely to revolutionize drug delivery systems to a new level, though need time to evolve.

scholarly journals Calculating the activation energies of nickel, manufactured using 3D printing technology, with multichannel hydrogen diffusion model

2019 ◽  
Vol 121 ◽  
pp. 04017
Author(s):  
Petr Zumberov ◽  
Sergey Kolesov ◽  
Vladimir Polyansky ◽  
Evgeniy Varshavchik
Keyword(s):  
3D Printing ◽  
Hydrogen Diffusion ◽  
Mathematic Model ◽  
Activation Energies ◽  
Modern World ◽  
Printing Technology ◽  
High Entropy ◽  
3D Printing Technology ◽  
3D Printed ◽  
Vacuum Heating

In modern world more and more materials with extreme properties are being used: high alloys, high-entropy alloys, nanostructured materials, etc. The extreme properties of these materials make them especially sensitive to hydrogen diffusion. Hydrogen can severely impair their properties and cause failures in structures and machines the material is used in. Nowadays, when structures and components are becoming increasingly complex, the use of 3D printing technology is becoming more widespread. Components made using 3D printing technologies are usually layered, which increase the amount of hydrogen that can diffuse into the material. The amount of hydrogen concentration in 3D printed nickel samples has been determined using vacuum heating method in hydrogen analyzer AV-1. The samples were held at different constant temperatures and the total amount of hydrogen extracted at those temperatures was calculated. A mathematic model was developed to evaluate the amount of hydrogen extracted at a given temperature. The evaluation was then compared to the experiment results, and the validity of the mathematical model and the selected hydrogen activation energies was verified.

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