scholarly journals The Ocular Surface and the Coronavirus Disease 2019: Does a Dual ‘Ocular Route’ Exist?

2020 ◽  
Vol 9 (5) ◽  
pp. 1269 ◽  
Author(s):  
Pietro Emanuele Napoli ◽  
Matteo Nioi ◽  
Ernesto d’Aloja ◽  
Maurizio Fossarello
Keyword(s):  
Ocular Surface ◽  
Tear Film ◽  
Underlying Mechanism ◽  
Point Of View ◽  
World Health ◽  
Surface System ◽  
Important Health ◽  
Long Time ◽  
The Moment ◽  
Health Organization

Coronavirus disease 2019 (COVID-19) is an important health problem that was defined as a pandemic by the World Health Organization on 11 March 2020. Although great concern has been expressed about COVID-19 infection acquired through ocular transmission, its underlying mechanism has not currently been clarified. In the current work, we analyzed and elucidated the two main elements that should be taken into account to understand the “ocular route”, both from a clinical and molecular point of view. They are represented by the dynamism of the ocular surface system (e.g., the tear film turnover) and the distribution of ACE2 receptors and TMPRSS2 protein. Although it seems, at the moment, that there is a low risk of coronavirus spreading through tears, it may survive for a long time or replicate in the conjunctiva, even in absence of conjunctivitis signs, indicating that eye protection (e.g., protective goggles alone or in association with face shield) is advisable to prevent contamination from external droplets and aerosol.

Flouride and Nitrate Status of Some Ground Waters in Chittor District of Rajasthan State (India)

2018 ◽  
Vol 6 (9) ◽  
pp. 119
Author(s):  
Trapti Sharma ◽  
R. P. Nagar ◽  
R. C. Gaur ◽  
Pooja Gupta ◽  
Charanjit Kaur
Keyword(s):  
Point Of View ◽  
World Health ◽  
Indian Council ◽  
Standard Methods ◽  
Ground Waters ◽  
Drinking Waters ◽  
Health Organization ◽  
Research World ◽  
Drinking Purpose

In Rajasthan state the ground waters of some areas like Ramganj-mandi, Morak, Barmer, Jaisalmer, Chittor and Udaipur etc. are susceptible from drinking point of view.To test the quality of groundwater in Chittor district 14, ground water samples were collected from various places and analyzed for pH, E.C., Fluoride and Nitrate parameters by standard methods (A.P.H. A., Washington, USA, 1995). The study revealed that none of the ground waters was found suitable completely from drinking point of view. Some are having electrical conductivity > 1.4 dS/m, some are having pH >8.5, some area having fluoride >1.5 ppm and some are having nitrate>45 ppm. These are the limits of various parameters permitted by various International authorities like Bureau of Indian Standard, Indian Council of Medical Research,world health Organization etc. for drinking waters. So, it is recommended to the residents of above areas to use water for drinking purpose only after reverse osmosis or adopting suitable method of removing excess of Fluoride and Nitrate for drinking water to avoid unwanted pathogenic diseases harmful for human health.

scholarly journals Probiotics: A Promising Candidate for Management of Colorectal Cancer

Cancers ◽  
2021 ◽  
Vol 13 (13) ◽  
pp. 3178
Author(s):  
Ashutosh Tripathy ◽  
Jayalaxmi Dash ◽  
Sudhakar Kancharla ◽  
Prachetha Kolli ◽  
Deviyani Mahajan ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Treatment Strategies ◽  
Intestinal Barrier ◽  
World Health ◽  
Intestinal Barrier Function ◽  
Cancer Type ◽  
Prevention Therapy ◽  
Long Time ◽  
Health Organization ◽  
Cancerous Cells

Colorectal cancer (CRC) is the World’s third most frequently diagnosed cancer type. It accounted for about 9.4% mortality out of the total incidences of cancer in the year 2020. According to estimated facts by World Health Organization (WHO), by 2030, 27 million new CRC cases, 17 million deaths, and around 75 million people living with the disease will appear. The facts and evidence that establish a link between the intestinal microflora and the occurrence of CRC are quite intuitive. Current shortcomings of chemo- and radiotherapies and the unavailability of appropriate treatment strategies for CRC are becoming the driving force to search for an alternative approach for the prevention, therapy, and management of CRC. Probiotics have been used for a long time due to their beneficial health effects, and now, it has become a popular candidate for the preventive and therapeutic treatment of CRC. The probiotics adopt different strategies such as the improvement of the intestinal barrier function, balancing of natural gut microflora, secretion of anticancer compounds, and degradation of carcinogenic compounds, which are useful in the prophylactic treatment of CRC. The pro-apoptotic ability of probiotics against cancerous cells makes them a potential therapeutic candidate against cancer diseases. Moreover, the immunomodulatory properties of probiotics have created interest among researchers to explore the therapeutic strategy by activating the immune system against cancerous cells. The present review discusses in detail different strategies and mechanisms of probiotics towards the prevention and treatment of CRC.

Comparativa de modelos multivariados basados en aprendizaje automático para la predicción del riesgo de diabetes en etapas tempranas

2021 ◽  
Author(s):  
◽  
Zayra Ramírez Gaytán
Keyword(s):  
World Health ◽  
Degenerative Diseases ◽  
Decision Tree Algorithm ◽  
Data Set ◽  
The World ◽  
Long Time ◽  
Life Threatening ◽  
Health Organization ◽  
Logistic Regression Algorithm ◽  
Asymptomatic Phase

Diabetes is one of the fastest-growing, life-threatening, chronic degenerative diseases. According to the World Health Organization (WHO), it has affected 422 million people worldwide in 2018. Approximately 50% of all people who suffer diabetes are not diagnosed due to the asymptomatic phase which usually lasts a long time. In this work, a data set of 520 instances has been used. The data set has been analyzed with the next three algorithms: logistic regression algorithm, decision trees and random forest. The results show that the decision tree algorithm had better performance with an AUC of 98%. Also, it was found the most common symptoms that a person with a risk of diabetes presents are polyuria, polydipsia and sudden weight loss.

PERFORMANCE OF THE NURSING TEAM IN THE HUMANIZATION OF NORMAL DELIVERY

2021 ◽  
Keyword(s):  
Latin American ◽  
World Health ◽  
Normal Delivery ◽  
Normal Birth ◽  
Natural Event ◽  
Quality Of Delivery ◽  
Delivery Services ◽  
Women's Role ◽  
The Moment ◽  
Health Organization

Historically, birth was considered a natural event, respected until the sixteenth century as an exclusively female movement. From the moment that the delivery began to happen inside the hospital with the participation of doctors in the process of the same, the woman stopped being the most important person and active of that event. Therefore, in order to change in this scenario, the World Health Organization and the Ministry of Health have been guiding and implementing behaviors that should be stimulated during childbirth, such as the presence of a companion, the supply of fluids, the use of non-invasive techniques for relief of pain and freedom of choice of birth position, among others. The study aims to verify in the literature the systematization of knowledge about the awareness of the benefits of normal delivery, pointing out the behaviors performed that favor the woman's role. This is a literature review, with descriptive and explanatory character, in the databases Scientific Electronic Library (ScIELO), Latin American and Caribbean Literature in Health Sciences (LILACS); And the National Library of Medicine (PUBMED, from 2008 to 2019), using the following descriptors: normal delivery, humanization, humanization in normal birth, women's role, and the result was three categories: The synthesis of the articles allowed us to understand that there are already some changes in the care of women during labor, but that there is still a lack of knowledge about the role of women in the labor market. It is concluded that in order for women to take part in labor and delivery, humanization becomes necessary, which is evidenced by the need to improve access and quality of delivery services.

scholarly journals IMPORTANCE OF CLASSICAL MORPHOLOGY IN THE DIAGNOSIS OF MYELODYSPLASTIC SYNDROME

2015 ◽  
Vol 7 ◽  
pp. e2015035 ◽  
Author(s):  
Rosangela Invernizzi ◽  
Federica Quaglia ◽  
Matteo Giovanni Della Porta
Keyword(s):  
Molecular Techniques ◽  
Classification Systems ◽  
World Health ◽  
Hematopoietic Stem ◽  
Morphological Alterations ◽  
Diagnosis And Classification ◽  
The Moment ◽  
Health Organization ◽  
Selection Of

Myelodysplastic syndromes (MDS) are hematopoietic stem cell disorders characterized by dysplastic, ineffective, clonal and neoplastic hematopoiesis. MDS represent a complex hematological problem: differences in disease presentation, progression and outcome  have necessitated the use of classification systems to improve diagnosis, prognostication and treatment selection. However, since a single biological or genetic reliable diagnostic marker has not yet been discovered for MDS, quantitative and qualitative dysplastic morphological alterations of bone marrow precursors and of peripheral blood cells are still fundamental for diagnostic classification. In this paper World Health Organization (WHO) classification refinements and current minimal diagnostic criteria proposed by expert panels are highlighted and related problematic issues are discussed. The recommendations should facilitate diagnostic and prognostic evaluations in MDS and selection of patients for new effective targeted therapies. Although in the future morphology should be supplemented with new molecular techniques, the morphological approach, at least for the moment, is still the cornerstone for the diagnosis and classification of these disorders.

scholarly journals Correlation of Parenting and Nutrient Intake with Stunting in Children 24-59 Months

2020 ◽  
Vol 2 (1) ◽  
pp. 280-285
Author(s):  
Nelly SD Situmeang ◽  
Etti Sudaryati ◽  
Jumirah
Keyword(s):  
Correlation Analysis ◽  
Nutrient Intake ◽  
Pearson Correlation ◽  
World Health ◽  
Cross Sectional ◽  
Growth Standards ◽  
Long Time ◽  
Surveillance Programs ◽  
Cross Sectional Design ◽  
Health Organization

Stunting is a chronic nutritional problem due to insufficient intake for a long time, in Indonesia the prevalence is high. The World Health Organization (WHO) classifies if the length/height z score is below −2 SD. The purpose of this study was to analyze the correlation between parenting, and nutrient intake (energy and protein) with stunting in children aged 24-59 years. This study used a cross sectional design with a sample of 117 children. Data collection was carried out with questionnaire instruments for parenting, and 24-hour food recall for nutritional intake. Data stunting was performed by comparing the height of the children measured by the WHO growth standards. Correlation analysis using Pearson correlation analysis. The results showed that the prevalence of stunting for children aged 24-59 months was 50.4%. There was a significant correlation between parenting with stunting (r = 0.287 and p = 0.02), energy intake with stunting (r = 0.215 and p = 0.020) and protein intake with stunting (r = 0.354 and p = 0.0001). It is recommended that the Ministry of Health improve nutrition surveillance programs, and encourage the community to monitor the growth of children under five years every month in health services.

Impact of Equine-Assisted Activities on Quality of Life and Relational Skills for Older Adults With Dementia: A Mixed-Methodology Research

2021 ◽  
Vol 75 (Supplement_2) ◽  
pp. 7512520401p1-7512520401p1
Author(s):  
Charmaine Lim ◽  
Manisha Sheth
Keyword(s):  
Quality Of Life ◽  
Mixed Methodology ◽  
World Health ◽  
Significant Difference ◽  
The Moment ◽  
Health Organization ◽  
Equine Assisted ◽  
Primary Author ◽  
Relational Skills

Abstract Date Presented Accepted for AOTA INSPIRE 2021 but unable to be presented due to online event limitations. The purpose of this research was to examine the efficacy of a 9-week equine-assisted program named "Horse in the Moment." Mixed-methodology research was conducted to explore the effectiveness of equine-assisted activities on quality of life (QOL) and relational skills for individuals diagnosed with dementia. Pre and post scores on World Health Organization QOL showed significant difference. Families of the participants also reported improvements in communication and socialization. Primary Author and Speaker: Charmaine Lim Additional Authors and Speakers: Manisha Sheth

NEW CORONOVIRUS INFECTION: CLINICAL AND PATHOGENETIC ASPECTS OF COVID-19 IN PREGNANT WOMEN

2021 ◽  
pp. 57-62
Author(s):  
Allakhyarov D.Z. ◽  
Petrov Yu.A. ◽  
Chernavsky V.V.
Keyword(s):  
Pregnant Women ◽  
The Body ◽  
World Health ◽  
Upper Respiratory Tract ◽  
Global Pandemic ◽  
High Prevalence ◽  
Coronavirus Infection ◽  
The Moment ◽  
Health Organization ◽  
The Impact

This article presents reviews of literature sources on the clinical and pathogenetic aspects of the course of a new coronovirus infection in pregnant women, in order to analyze the features of the course of COVID-19 in pregnant women and to assess the impact of infection on the body of a woman and a fetus. Pregnancy is a special physiological condition, during which a number of changes occur in the body, not only in the hormonal status, but also in the immune system. The urgency of this problem is due to the high prevalence of new coronavirus infection among the population. On March 12, 2020, the World Health Organization (WHO), as a result of the dynamic development of the epidemic in many countries and continents, declared a global pandemic of the contagious disease COVID-19 caused by the SARS-CoV-2 virus. According to available studies, pregnant women are more susceptible to a more severe course of infectious diseases affecting the upper respiratory tract. According to various studies, a new coronavirus infection can lead to premature birth, miscarriage, and preeclampsia. Separate studies show increased mortality in pregnant women diagnosed with COVID-19. The SARS-CoV-2 virus does not have a direct teratogenic effect on the fetus, but it can indirectly lead to harmful effects on the developing organism. Special attention should be paid to the issue of vaccination of pregnant women against a new coronavirus infection, at the moment there is no accurate data on the effect of the vaccine on the body of the pregnant woman and the fetus. In this regard, the question of the impact of a new coronavirus infection on the course of pregnancy has become relevant.

scholarly journals Exploring WHO Communication during the COVID 19 Pandemic through the WHO Website Based on W3C Guidelines: Accessible for All?

2020 ◽  
Vol 17 (16) ◽  
pp. 5663
Author(s):  
Elena Fernández-Díaz ◽  
Patricia P. Iglesias-Sánchez ◽  
Carmen Jambrino-Maldonado
Keyword(s):  
The Elderly ◽  
Point Of View ◽  
World Health ◽  
Health Crisis ◽  
Digital Version ◽  
Recommendations For Action ◽  
The World ◽  
Accessibility Guidelines ◽  
Health Organization ◽  
Health Content

Health crisis situations generate greater attention and dependence on reliable and truthful information from citizens, especially from those organisations that represent authority on the subject, such as the World Health Organization (WHO). In times of global pandemics such as COVID-19, the WHO message “health for all” takes on great communicative importance, especially from the point of view of the prevention of the disease and recommendations for action. Therefore, any communication must be understandable and accessible by all types of people, regardless of their technology, language, culture or disability (physical or mental), according to the World Wide Web Consortium (W3C), taking on special relevance for public health content. This study analysed whether the WHO is accessible in its digital version for all groups of citizens according to the widely accepted standards in the field of the Internet. The conclusion reached was that not all the information is accessible in accordance with the Web Content Accessibility Guidelines 2.1, which implies that there are groups that are, to some extent, left out, especially affecting the elderly. This study can contribute to the development of proposals and suggest ways in which to improve the accessibility of health content to groups especially vulnerable in this pandemic.

scholarly journals Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Comprehensive Review

Diagnostics ◽  
2019 ◽  
Vol 9 (3) ◽  
pp. 91 ◽  
Author(s):  
Mateo Cortes Rivera ◽  
Claudio Mastronardi ◽  
Claudia Silva-Aldana ◽  
Mauricio Arcos-Burgos ◽  
Brett Lidbury
Keyword(s):  
Chronic Fatigue Syndrome ◽  
Age Of Onset ◽  
Chronic Fatigue ◽  
The United States ◽  
Myalgic Encephalomyelitis ◽  
World Health ◽  
Fatigue Syndrome ◽  
Control And Prevention ◽  
The Moment ◽  
Health Organization

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating chronic disease of unknown aetiology that is recognized by the World Health Organization (WHO) and the United States Center for Disease Control and Prevention (US CDC) as a disorder of the brain. The disease predominantly affects adults, with a peak age of onset of between 20 and 45 years with a female to male ratio of 3:1. Although the clinical features of the disease have been well established within diagnostic criteria, the diagnosis of ME/CFS is still of exclusion, meaning that other medical conditions must be ruled out. The pathophysiological mechanisms are unclear but the neuro-immuno-endocrinological pattern of CFS patients gleaned from various studies indicates that these three pillars may be the key point to understand the complexity of the disease. At the moment, there are no specific pharmacological therapies to treat the disease, but several studies’ aims and therapeutic approaches have been described in order to benefit patients’ prognosis, symptomatology relief, and the recovery of pre-existing function. This review presents a pathophysiological approach to understanding the essential concepts of ME/CFS, with an emphasis on the population, clinical, and genetic concepts associated with ME/CFS.

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