scholarly journals Reference Values for Cardiorespiratory Fitness in Healthy Koreans

2019 ◽  
Vol 8 (12) ◽  
pp. 2191 ◽  
Author(s):  
Won Young Jang ◽  
Woohyeun Kim ◽  
Dong Oh Kang ◽  
Yoonjee Park ◽  
Jieun Lee ◽  
...  
Keyword(s):  
Cardiorespiratory Fitness ◽  
Reference Values ◽  
Age Groups ◽  
National Standards ◽  
Healthy Population ◽  
Vo2 Max ◽  
Sports Science ◽  
Age Related ◽  
Significant Difference ◽  
Study Population

We investigated reference values for cardiorespiratory fitness (CRF) for healthy Koreans and Koreans with coronary heart disease (CHD) and used them to identify inter-ethnic differences in CRF, differences over time in CRF, and differences in CRF between the healthy population and patients with CHD. The study population for healthy Koreans was derived from the database of KISS FitS (Korea Institute of Sports Science Fitness Standards) between 2014 and 2015. The study population for Koreans with CHD was derived from the database of the Korea University Guro Hospital Cardiac Rehabilitation Registry between June 2015 and December 2018. In healthy Koreans, there was a significant difference between sex and age groups for VO2 max. The VO2 max of healthy Koreans differed from that of Westerners in age-related reference values. Our results were not significantly different from those of the Korean population in the past, except for a small decline in the young population. There seemed to be a clear inter-ethnic difference in CRF. We could also identify signs of small change in CRF in younger age groups. Therefore, CRF should be assessed according to ethnic or national standards, and it will be necessary to establish a reference for each nation or ethnicity with periodic updates.

P4339Reference values for cardiorespiratory fitness in healthy Koreans: compared to western nations and nomogram

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
W Y Jang ◽  
W Kim ◽  
D O Kang ◽  
Y Park ◽  
E J Park ◽  
...  
Keyword(s):  
Oxygen Uptake ◽  
Exercise Capacity ◽  
Cardiorespiratory Fitness ◽  
Reference Values ◽  
Maximal Oxygen Uptake ◽  
National Standards ◽  
Specific Reference ◽  
P Value ◽  
Sports Science ◽  
Korean Adults

Abstract Introduction Cardiorespiratory Fitness (CRF), defined as the integrated ability to properly oxygenate skeletal muscles during physical activity, is associated with a high risk of cardiovascular disease and all-cause mortality. The reference range for CRF may differ among nations, with Asians under-represented in previous data. Purpose In this study, we sought to establish reference values of CRF for Asians using a recent Korean cohort. Methods We analyzed 2646 healthy Korean adults recently enrolled in the Korea Institute of Sports Science Fitness Standards (KISS FitS) project with estimated maximal oxygen uptake (VO2max) values during treadmill test. Patients with cardiovascular or renal disease, systemic infection, pregnant women and those with orthopedic injuries unable to measure physical fitness were excluded. Age-specific mean VO2max values were compared with those from recent American, Norwegian, Danish cohorts and old Korean data. Results Age-specific reference values for healthy Korean adults in this cohort were as shown (Table). We were able to draw a nomogram to predict exercise capacity for a given age and MET value (Figure). When compared to other countries, less CRF reduction by aging was seen in Asians than in other Westerners. When compared to old Korean data from the 1980s, values were similar after adjustment for difference in methods, except for those under 30 years old which were decreased. Exercise capacity of healthy Korean Men Women Age VO2max (ml/kg/min) N P-value for trend Age VO2max (ml/kg/min) N P-value for trend 19–29 42.3±6.3± 209 <0.01 19–29 34.3±4.3± 110 <0.01 30–39 42.0±5.0± 170 39–39 32.2±4.5± 211 40–49 41.4±5.6± 238 40–49 30.8±4.6± 284 50–59 38.0±5.7± 274 50–59 28.3±4.6± 367 60–69 32.4±6.2± 134 60–69 26.0±5.7± 336 70–79 27.2±5.6± 83 70–79 23.9±4.4± 195 >80 24.1±4.0± 11 >80 21.0±3.7± 24 Total 38.6±7.4± 1119 Total 28.5±5.8 1527 Data are presented as mean ± standard deviation. VO2max, maximal oxygen uptake; N, number. Nomogram of exercise capacity in Koreans Conclusions While there was no significant change in CRF over time in the same ethnic group, there was a clear inter-ethnic difference. CRF should be assessed according to ethnic or national standards, and it is necessary to establish a reference for each nation or ethnicity with periodic updates. Acknowledgement/Funding National Sports Promotion Fund of the Korea Sports Promotion Foundation in 2015

scholarly journals The prevalence of diphtheria immunity in healthy population in Poland

2001 ◽  
Vol 126 (2) ◽  
pp. 225-230 ◽  
Author(s):  
J. WALORY ◽  
P. GRZESIOWSKI ◽  
W. HRYNIEWICZ
Keyword(s):  
Geometric Mean ◽  
Age Groups ◽  
Significant Proportion ◽  
Reference Method ◽  
Vero Cells ◽  
Healthy Population ◽  
Serum Samples ◽  
Booster Immunization ◽  
Age Related ◽  
Significant Difference

The degree of seroprotection against diphtheria in Poland was evaluated by determination of IgG antibodies to Corynebacterium diphtheriae toxin (IgG-DTAb). The study population consisted of 4829 healthy subjects aged from 1 day to 85 years from 7 regions of Poland. Serum samples collected between 1996 and 1998 were assayed for IgG-DTAb antibodies using a toxoid enzyme immunoassay. Neutralization of toxin in Vero cells was performed as a reference method with the WHO standard for human diphtheria antitoxin. The study revealed a lack of seroprotection (IgG-DTAb < 0·1 IU/ml) in 23 % of individuals, basic seroprotection (0·1–1·0 IU/ml) in 64 %, and effective seroprotection (> 1·0 IU/ml) in 13 %. The non-protected group consisted of non-vaccinated children below 2 months of age (10 %), individuals between 2 months and 18 years old (20 %) and greater than 19 years old (70 %). Of the adults, 32 % were seronegative, 63 % had basic seroprotection and only 5 % were fully protected; 43 % of adults between 30 and 64 years, who had not been vaccinated at least during the previous 10 years were not protected against diphtheria. The geometric mean titre (GMT) of IgG-DTAb was 0·25 IU/ml in the total population. Age-related GMTs differed significantly from each other and were higher (0·44 IU/ml) in individuals from 2 months to 18 years old, compared with 0·14 IU/ml and 0·17 IU/ml in children under 2 months and adults, respectively. No significant difference was found in the GMTs of men and women in all age groups. We conclude that the currently used vaccination programme in Poland is highly effective and assures protection against diphtheria in the majority of the population in the 10-year period following the last booster. However, a significant proportion of adults between 30 and 64 years lack protection and this indicates a need for booster immunization for this group.

Determination of reference values for serotonin concentration in platelets of healthy newborns, children, adults, and elderly subjects by HPLC with electrochemical detection

1990 ◽  
Vol 36 (12) ◽  
pp. 2117-2120 ◽  
Author(s):  
E Flachaire ◽  
C Beney ◽  
A Berthier ◽  
J Salandre ◽  
C Quincy ◽  
...  
Keyword(s):  
Electrochemical Detection ◽  
Reference Values ◽  
High Performance ◽  
Elderly Subjects ◽  
Healthy Population ◽  
Serotonin Concentration ◽  
Platelet Serotonin ◽  
Age Related ◽  
Significant Difference

Abstract We adapted a high-performance liquid chromatographic method with electrochemical detection (Clin Chim Acta 1984;139:1-12) to the determination of platelet serotonin. We used this method to determine platelet serotonin reference values in a healthy population, measuring platelet serotonin concentration in the following subjects: 31 newborns (16 girls, 15 boys); 41 children (11 girls, 30 boys), ages 20 months to 15 years; 56 adults (26 women, 30 men), ages 20 to 58 years; and 20 elderly subjects (16 women, four men), ages 65 to 94 years. There was no significant difference in platelet serotonin concentration between sexes in each age group. However, significant changes (P less than 0.001) were observed between the newborns (mean +/- SD: 1.67 +/- 0.74 nmol/10(9) platelets) and the children (4.09 +/- 1.04) or the adults (3.81 +/- 0.87). Moreover, the platelet serotonin concentration in the elderly subjects (2.57 +/- 1.12) was significantly (P less than 0.001) lower than in the adults and children and significantly higher (P less than 0.01) than in the newborns. Such age-related differences must be taken into consideration when data from neurological or psychiatric patients and control subjects are compared.

scholarly journals Maximum mouth opening in healthy children and adolescents in Istanbul

2018 ◽  
Vol 6 (1) ◽  
Author(s):  
Mine Koruyucu ◽  
Derya Tabakcilar ◽  
Figen Seymen ◽  
Koray Gençay
Keyword(s):  
Age Groups ◽  
Clinical Signs ◽  
Mouth Opening ◽  
Healthy Children ◽  
Class Iii ◽  
Age Related ◽  
Significant Difference ◽  
Study Population ◽  
Interincisal Distance ◽  
The Mean

Objectives: Mouth opening capacity is often regarded as one of the important parameters for evaluating the function of the temporomandibular joint (TMJ) and masticatory muscle status. A reduced mouth opening capacity may be one of the first clinical signs of TMJ involvement. The purpose of this study was to create age related percentiles for the maximal interincisal distance (MID) of healthy children. Methods: The patients admitted for routine dental examinations to Istanbul University Faculty of Dentistry, Department of Pedodontics were included in this study. The interincisal measurements were performed with metallic calliper and also malocclusions were recorded for all children. Oneway Anova test, Tukey HDS test, Tamhane’s T2 test and Student t test were used for statistical analysis. Results: The study population comprised of 1059 (569 males, 490 females), 3-to 15-year-old (mean age 8.82±3.06) children. The mean score of maximal inter-incisal distance was found 33.24±5.54 for females; 33.32±5.71 for males. There was no statistically significant difference according to gender (p=0.815; p>0.05). The mean score of maximal inter-incisal distance was found 28.63±4.34 for 3-5 years; 33.52±4.84 for 6-11 years; 37.35±5.52 for 12-15 years children. Statistically significant differences were found between age groups (p: 0.001; p<0.01). The mean score of maximal inter-incisal distance was found 32.9±5.6 for class I; 34.92±5.51 for class II; 35.2±5.36 for class III malocclusions. Statistically significant differences were found between malocclusion groups (p:0.001; p<0.01). Conclusion: The result of this study indicated that positive relationship between the maximum mouth opening and age and malocclusion.

The influence of osteopathic correction on the rate of various rhythms of the body

2019 ◽  
pp. 64-71 ◽  
Author(s):  
A. E. Chernikova ◽  
Yu. P. Potekhina
Keyword(s):  
Heart Rate ◽  
Respiratory Rate ◽  
Age Groups ◽  
Biomechanical Properties ◽  
Dispersion Analysis ◽  
The Body ◽  
Body Tissues ◽  
Age Related ◽  
Significant Difference ◽  
Before And After

Introduction. An osteopathic examination determines the rate, the amplitude and the strength of the main rhythms (cardiac, respiratory and cranial). However, there are relatively few studies in the available literature dedicated to the influence of osteopathic correction (OC) on the characteristics of these rhythms.Goal of research — to study the influence of OC on the rate characteristics of various rhythms of the human body.Materials and methods. 88 adult osteopathic patients aged from 18 to 81 years were examined, among them 30 men and 58 women. All patients received general osteopathic examination. The rate of the cranial rhythm (RCR), respiratory rate (RR) heart rate (HR), the mobility of the nervous processes (MNP) and the connective tissue mobility (CTM) were assessed before and after the OC session.Results. Since age varied greatly in the examined group, a correlation analysis of age-related changes of the assessed rhythms was carried out. Only the CTM correlated with age (r=–0,28; p<0,05) in a statistically significant way. The rank dispersion analysis of Kruskal–Wallis also showed statistically significant difference in this indicator in different age groups (p=0,043). With the increase of years, the CTM decreases gradually. After the OC, the CTM, increased in a statistically significant way (p<0,0001). The RCR varied from 5 to 12 cycles/min in the examined group, which corresponded to the norm. After the OC, the RCR has increased in a statistically significant way (p<0,0001), the MNP has also increased (p<0,0001). The initial heart rate in the subjects varied from 56 to 94 beats/min, and in 15 % it exceeded the norm. After the OC the heart rate corresponded to the norm in all patients. The heart rate and the respiratory rate significantly decreased after the OC (р<0,0001).Conclusion. The described biorhythm changes after the OC session may be indicative of the improvement of the nervous regulation, of the normalization of the autonomic balance, of the improvement of the biomechanical properties of body tissues and of the increase of their mobility. The assessed parameters can be measured quickly without any additional equipment and can be used in order to study the results of the OC.

EXPRESS: Serum Carbohydrate Antigen72-4 levels decrease with age in females but not males in Beijing, China

2021 ◽  
pp. 000456322110269
Author(s):  
Tongmei Duan ◽  
Xun Chen ◽  
Jing Wu ◽  
Ronghai Li ◽  
Huijuan Guo ◽  
...  
Keyword(s):  
Age Groups ◽  
Reference Interval ◽  
Carbohydrate Antigen ◽  
Female Group ◽  
Healthy Population ◽  
Age Difference ◽  
Significant Difference ◽  
The Difference ◽  
And Gender ◽  
Beijing China

Objective: Carbohydrate antigen 72-4 (CA72-4) is widely used in the diagnosis and monitoring of many cancers. However, there are few studies on the differences of CA72-4 levels in terms of age and gender. Methods: 10957 healthy subjects were divided into two groups according to gender and three age groups. The serum CA72-4 were detected. Statistical analysis was performed by SPSS. Results: The CA72-4 level in female group was significantly higher than that in male group. The level of CA72-4 gradually decreased with age. Compared with the age >60 group, the CA72-4 levels were increased in the age 46-60 group and 16-45 group (P >0.05, respectively). To better observe the age difference, the age 16-45 and 46–60 group were combined into the age 16-60 group. In comparison to the age >60 group, the CA72-4 level of age 16-60 group was significantly increased (P =0.000). In the age >60 group, there was no difference between genders. Nevertheless, the difference between the sexes in the age 16-60 group was significant (P =0.023). Conclusions: The reference interval of CA72-4 for local healthy population was established. CA72-4 levels gradually decreased with the increase of age, and CA72-4 level in females aged 16-60 years (0-18.0 U/mL) was higher than in males (0-14.5 U/mL), however there was no gender difference in the age group above 60 years old (0-14.5 U/mL). Moreover, male CA72-4 was no significant difference among all age groups, while the potential mechanism of female changes with age needed further study.

scholarly journals Age Related Variation in Feminine Handwriting among Population Groups of Delhi, India

2018 ◽  
Vol 6 (1) ◽  
pp. 1-6
Author(s):  
Vijit Deepani ◽  
A.K Kapoor ◽  
Monika Saini
Keyword(s):  
Significant Variation ◽  
Research Result ◽  
Age Groups ◽  
Population Group ◽  
Population Groups ◽  
Related Variation ◽  
Age Related ◽  
Significant Difference ◽  
Micro Features ◽  
Lower Loop

Background: Handwriting is a uniquely human trait which progresses and evolves during lifetime and declines with age. The aim of the present paper is to assess variation in handwriting features with age among female writers of select population groups of Delhi, India (for roman script). Method: A total of 405 handwritten samples were obtained from female (n=405) writers in the age range of 14-60 years. Writers were stratified into three age groups (≤ 18 years, 19-38 years and ≥39 years) in accordance to population group. Macro- and micro-features of handwriting were extracted from the scanned handwritten samples. These features were subjected to statistical analysis in the objective driven research. Result: The mean difference among age groups for pen pressure, height of handwriting and handwriting connectivity was statistically significant (p < 0.001). Significant difference was also observed among age groups for all micro-features of handwriting selected in the present study, namely, nature of ‘i’ – dot (p < 0.001), nature of lower loop of ‘g’ (p < 0.01); nature of‘d’- stem (p < 0.01), nature of ‘m’-hump (p < 0.05) and ‘r’- shape (p < 0.001). Conclusion: The present study showed that there was a significant variation in both macro- and micro- features of handwriting with respect to age of the writer. Pen pressure, height of handwriting and handwriting connectivity were prominent macro-features that addressed age related variation in handwriting. In addition, significant variation was observed among age groups for all micro-features of handwriting selected in the present study. The present study has immense forensic significance as it can assist to analyze age of the writer on the basis of handwriting characteristics.

scholarly journals MONITORING HEALTH INDICES IN FEMALES OF DIFFERENT AGE GROUPS

2019 ◽  
Vol 98 (8) ◽  
pp. 827-832
Author(s):  
Olga S. Aminova ◽  
N. N. Tyatenkova ◽  
Yu. E. Uvarova ◽  
S. V. Yakovlev
Keyword(s):  
Age Groups ◽  
Blood Cholesterol ◽  
Dynamic State ◽  
Social Functions ◽  
Total Blood ◽  
Health Indices ◽  
Age Related ◽  
Significant Difference ◽  
Definition Of ◽  
Functional Examination

Introduction. Health - is a complex and at the same integral multivariable dynamic state, developing in the process of realization of the genetic potential in a particular social and ecological environment, which permits a person to carry out its biological and social functions. Material and methods Health indices deteriorate with age. In this situation, special attention should be paid to older age groups. However, recent studies prefer to investigate young people. Data about health status of different age groups is not well investigated. Survey of 415 women aged 20 to 59 years residing on Yaroslavl region has been performed. Evaluation of age-related changes in health indices included questionnaire, morphological and functional examination, definition of physical development and adaptative potential according to the calculated indices and reference values. Results. The study examined the dynamics of health indices and established a statistically significant difference in the gain in body weight, blood pressure, total blood cholesterol, decreased lung capacity relative to body mass and adaptive capacity of the cardiovascular system with the age. Analysis of the incidence showed that chronic diseases incidence has increased from 56% in the 20-29 years group to 88% among 50-59 years old persons. Diseases of cardiovascular and musculoskeletal system (48-49%) become predominant pathology with age. Evaluation of lifestyle shows that poor physical activity and sleep disorders were registered in 77% and 32% respectively regardless of age. Eating disorders were registered in 41% patients aged of 20-29 years. Ratio tobacco users decreased from 23% to 10% with age, while the number of cigarettes smoked per day was increased. Сonclusion. The study established the negative dynamics of health indices to be typical for women aged 20-59 years, while the rate of deterioration exceeds the average one in the Russian population. Self-preservation behavior is not predominant in all age groups, it is typical only for 3% of young women and 11-15% of other groups.

scholarly journals Pattern of Glucose Tolerance among Patients with Peripheral Spondyloarthritis

2020 ◽  
Vol 5 (9) ◽  
pp. 773-777
Author(s):  
A T M Tanveer Hasan ◽  
Al-Mamun .
Keyword(s):  
Diabetes Mellitus ◽  
General Population ◽  
Glucose Tolerance ◽  
Inflammatory Diseases ◽  
Age Groups ◽  
Oral Glucose ◽  
Increased Risk ◽  
Significant Difference ◽  
Study Population ◽  
Peripheral Spondyloarthritis

Peripheral spondyloarthritis is a variant of spondyloarthritis which usually has a chronic course. There is an increased risk of cardiovascular diseases among patients with chronic inflammatory diseases in general. Coexisting diabetes mellitus can potentially add to the risk. The objective of this study was to determine the frequency of glucose intolerance in patients with spondyloarthritis The study was conducted among 35 participants with peripheral spondyloarthritis who visited the Department of Rheumatology, Enam Medical College & Hospital, Savar, Dhaka, Bangladesh from September, 2018 to January, 2020. The participants underwent either oral glucose tolerance test or estimation of HbA1C. The mean age of participants was 43.96 years. The majority (80%) of them were young to muddle-aged (≤40 years). 22.9% of the participants were prediabetic. Diabetes mellitus was found to be present in 37.1% of the participants. There was no significant difference between the study population and the general population in terms of frequency of prediabetes. But the frequency of diabetes in the study population was higher than that in the general population. There was no significant difference between males and females with regard to the frequencies of prediabetes and DM. Moreover, there was no significant difference in the frequencies of prediabetes and DM between young and middle-aged to elderly population. Considering the greater burden of DM among patients with peripheral spondyloarthritis across all age groups, routine screening for DM may be indicated in these individuals.

scholarly journals Hematological parameters of the blood count in a healthy population of pregnant women in the Northwest of Morocco (Tetouan-M'diq-Fnideq provinces)

2018 ◽  
Vol 29 ◽  
Author(s):  
Saad Bakrim ◽  
Youssef Motiaa ◽  
Ali Ouarour ◽  
Azlarab Masrar
Keyword(s):  
Pregnant Women ◽  
Reference Values ◽  
Blood Count ◽  
Complete Blood Count ◽  
Hematological Parameters ◽  
Control Group ◽  
Mean Corpuscular Hemoglobin ◽  
Healthy Population ◽  
Corpuscular Hemoglobin ◽  
Significant Difference

Introduction: numerous biological parameters are physiologically modified during normal pregnancy, in particular hematology. The knowledge of these modifications of the maternal body by biologists and clinicians allows the screening of possible anomalies. In Morocco, the reference values of the complete blood count test for pregnant woman are missing, as are those specific to different trimesters of pregnancy. The aim of this study is to look for the reference values for healthy pregnant women of the Northwest region of Morocco, to compare them to those of non-pregnant women (control) and to those of the literature. Methods: blood samples were taken voluntarily from 3898 healthy pregnant women from 18 to 46 years old who presented themselves at the center of health Kalaa and at the service of gynecology obstetrics of the Provincial Hospital Center of M'diq (Morocco), for prenatal care. To establish the reference intervals of the CBC for non-pregnant women, a control group was constituted by 7035 healthy women from 18 to 50 years old selected according to the Moroccan law of blood donation. The CBC was measured on a Sysmex KX21N® analyzer. For each sample a systematic blood smear was done to determine the leukocyte differential. Results: a statistically significant difference between the pregnant women and control group was noted (p < 0.05) for all the hematological parameters: red blood cells, hematocrit, hemoglobin, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, leukocytes, neutrophils, basophils, eosinophils, lymphocytes, monocytes, platelets and mean platelet volume. So, the comparison of the averages established between the first, second and third trimester of pregnancy showed the existence of a significant variation with regard to all the parameters of the CBC test looked for (p < 0.001). Conclusion: the present study provides additional baseline data for basic hematological parameters in healthy pregnant Moroccan women and concluded that pregnancy in women has the tendency to alter some hematological indices. For these reasons, there is an interest to take these modifications into account for optimal maternal and fetal medical care.

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