scholarly journals The Outcomes of Pancreatic Transplantation from Pediatric Donors–A Single Institution Experience

2019 ◽  
Vol 8 (9) ◽  
pp. 1386 ◽  
Author(s):  
Ito ◽  
Kenmochi ◽  
Aida ◽  
Kurihara ◽  
Kawai ◽  
...  
Keyword(s):  
Blood Glucose Concentration ◽  
Serum Insulin ◽  
Oral Glucose ◽  
Oral Glucose Tolerance ◽  
Pancreatic Transplantation ◽  
Single Institution ◽  
Oral Glucose Tolerance Tests ◽  
Glucose Tolerance Tests ◽  
Pediatric Donors ◽  
Pancreatic Graft

Objectives: The aim of this study was to compare the outcomes of pancreatic transplantation from pediatric donors younger than 15 years of age to the outcomes of pancreatic transplantation from adult donors. Methods: Sixty patients underwent pancreatic transplantation in our facility from August 2012 to June 2019. These patients were divided into two groups according to the age of the donor: Cases in which the donor was younger than 15 years of age were classified into the PD group (n = 7), while those in which the donor was older than 15 years of age were classified into the AD group (n = 53). The outcomes of pancreas transplantation were retrospectively compared between the two groups. Results: Pancreatic graft survival did not differ between the PD and AD groups. Furthermore, there were no differences in the HbA1c and serum creatinine levels at three months, with good values maintained in both groups. The results of oral glucose tolerance tests (OGTTs) revealed that the blood glucose concentration did not differ between the two groups. However, the serum insulin concentration at 30 min after 75 g glucose loading was significantly higher in the PD group. Conclusion: The outcomes of pancreatic transplantation from pediatric donors may be comparable to those of pancreatic transplantation from adult donors and the insulin secretion ability after transplantation may be better.

Low carbohydrate intake and oral glucose-tolerance tests

The Lancet ◽  
1998 ◽  
Vol 352 (9135) ◽  
pp. 1223 ◽  
Author(s):  
Keiji Yoshioka ◽  
Sadayoshi Yokoh ◽  
Toshihide Yoshida
Keyword(s):  
Glucose Tolerance ◽  
Carbohydrate Intake ◽  
Oral Glucose ◽  
Oral Glucose Tolerance ◽  
Low Carbohydrate ◽  
Oral Glucose Tolerance Tests ◽  
Glucose Tolerance Tests

scholarly journals ogttMetrics: Data structures and algorithms for oral glucose tolerance tests

F1000Research ◽  
2017 ◽  
Vol 6 ◽  
pp. 684
Author(s):  
Benjamin J. Stubbs ◽  
Keith Frankston ◽  
Marcel Ramos ◽  
Nancy Laranjo ◽  
Frank M. Sacks ◽  
...  
Keyword(s):  
Glucose Tolerance ◽  
Open Source Software ◽  
Oral Glucose ◽  
Oral Glucose Tolerance ◽  
Estimation Of Parameters ◽  
Large Clinical Trial ◽  
Oral Glucose Tolerance Tests ◽  
Open Source Software Package ◽  
Glucose Tolerance Tests ◽  
Data Structures And Algorithms

We describe an open source software package, ogttMetrics, to compute diverse measures of glucose metabolism derived from oral glucose tolerance tests (OGTTs). Tools are provided to organize, visualize and compare OGTT data from large cohorts. Numerical difficulties in estimation of parameters of the Bergman minimal model are described, and in one large clinical trial, the simpler closed form index of Matsuda is observed to lead to similar rankings of individuals with respect to insulin sensitivity, and similar inferences concerning effects of modifications to carbohydrate content and glycemic index of experimental diets.

Reversibility of endocrine changes produced in guinea pigs by exposure to cold

1965 ◽  
Vol 208 (1) ◽  
pp. 115-117 ◽  
Author(s):  
Harry Sobel ◽  
George C. Haberfelde ◽  
Albert E. Reeves
Keyword(s):  
Glucose Tolerance ◽  
Guinea Pigs ◽  
Room Temperature ◽  
Oral Glucose ◽  
Oral Glucose Tolerance ◽  
Definite Evidence ◽  
Exposure To Cold ◽  
Thyroid Glands ◽  
Oral Glucose Tolerance Tests ◽  
Glucose Tolerance Tests

Guinea pigs were exposed continuously to a temperature of 2–4 C for 6 months. They were then reacclimatized to room temperature, and after 4–6 months certain tests were carried out. During control collections and following exposure to cold the previously cold-exposed animals exhibited urinary corticoid excretion values which were approximately 10% below those of their controls. Following intraperitoneal injection of ACTH the response was approximately 20% greater. However, these differences were not statistically significant. Oral glucose tolerance tests revealed definite evidence of reduction in tolerance in the previously cold-exposed animals. Six animals exhibited 150-min values which exceeded by more than 20 mg/ 100 ml the highest value observed in the controls. Fourteen others whose values fell within this limit exhibited a statistically significant increase in the 150-min value as compared with the controls. The PBI values were the same in each group. There were no histological residues in the pituitary, adrenal, pancreas, and thyroid glands.

scholarly journals Estimating plasma glucose with the FreeStyle Libre Pro continuous glucose monitor during oral glucose tolerance tests in youth without diabetes

2019 ◽  
Vol 20 (8) ◽  
pp. 1072-1079 ◽  
Author(s):  
Nejla Ghane ◽  
Miranda M. Broadney ◽  
Elisabeth K. Davis ◽  
Robert W. Trenschel ◽  
Shavonne M. Collins ◽  
...  
Keyword(s):  
Glucose Tolerance ◽  
Plasma Glucose ◽  
Oral Glucose ◽  
Oral Glucose Tolerance ◽  
Continuous Glucose Monitor ◽  
Freestyle Libre ◽  
Oral Glucose Tolerance Tests ◽  
Glucose Tolerance Tests
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