scholarly journals Aseptic Ligatures Induce Marginal Peri-Implant Bone Loss—An 8-Week Trial in Rabbits

2019 ◽  
Vol 8 (8) ◽  
pp. 1248 ◽  
Author(s):  
David Reinedahl ◽  
Silvia Galli ◽  
Tomas Albrektsson ◽  
Pentti Tengvall ◽  
Carina B. Johansson ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Bone Resorption ◽  
Close Contact ◽  
Contact Point ◽  
Healing Time ◽  
Tissue Reaction ◽  
Clinical Value ◽  
Bone Contact ◽  
Soft Tissue Reactions ◽  
Tissue Reactions

The clinical value of ligature-induced experimental peri-implantitis studies has been questioned due to the artificial nature of the model. Despite repeated claims that ligatures of silk, cotton and other materials may not induce bone resorption by themselves; a recent review showed that the tissue reaction toward them has not been investigated. Hence, the current study aimed to explore the hard and soft tissue reactions toward commonly used ligature materials. A total of 60 dental implants were inserted into the femur (n = 20) and tibia (n = 40) of 10 rabbits. The femoral implants were ligated with sterile 3-0 braided silk in one leg and sterile cotton retraction chord in the other leg. The tibial implants were ligated with silk or left as non-ligated controls. All wounds were closed in layers. After a healing time of 8 weeks, femoral (silk versus cotton) and proximal tibial (silk versus non-ligated control) implants were investigated histologically. Distal tibial (silk versus non-ligated control) implants were investigated with real time polymerase chain reaction (qPCR). The distance from the implant-top to first bone contact point was longer for silk ligated implants compared to non-ligated controls (p = 0.007), but did not vary between cotton and silk. The ligatures triggered an immunological reaction with cell infiltrates in close contact with the ligature materials, adjacent soft tissue encapsulation and bone resorption. qPCR further demonstrated an upregulated immune response toward the silk ligatures compared to non-ligated controls. Silk and cotton ligatures provoke foreign body reactions of soft tissue encapsulation type and bone resorption around implants in the absence of plaque.

scholarly journals Bearing exchange in the management of pseudotumours

2013 ◽  
Vol 95 (4) ◽  
pp. 266-270 ◽  
Author(s):  
MA Kemp ◽  
A Mitra ◽  
T Mendes da Costa ◽  
RF Spencer
Keyword(s):  
Soft Tissue ◽  
Hip Resurfacing ◽  
Tissue Reaction ◽  
Wear Rates ◽  
Metal On Metal ◽  
Metal Wear ◽  
Soft Tissue Reactions ◽  
Tissue Reactions ◽  
Considerable Discussion ◽  
Ceramic On Ceramic

Introduction Soft tissue reactions following metal-on-metal (MoM) arthroplasty of the hip have been under considerable discussion. These reactions are seen following both hip resurfacing and MoM total hip arthroplasty (THA). The phenomenon may arise owing to shedding of metal particles in high wear states, hypersensitivity with normal metal wear rates or a combination of the two. Methods Three patients were identified who had developed a soft tissue reaction (pseudotumour) following MoM hip resurfacing procedures. The prostheses were revised to ceramic-on-ceramic (CoC) THA with only minimal debridement of the pseudotumour. Pre and postoperative magnetic resonance imaging was performed to assess the size of the lesions. Results Progressive and satisfactory resolution of the associated pseudotumours was identified following revision of the prostheses to CoC THA. Conclusions In the early stages of pseudotumour formation following MoM hip resurfacing, this potentially devastating condition can be managed adequately with revision to a CoC bearing THA with minimal soft tissue excision.

Midterm outcomes of total hip arthroplasty with a modular Birmingham head

2019 ◽  
pp. 112070001987738 ◽  
Author(s):  
Duncan W Cushnie ◽  
Brent A Lanting ◽  
Richard McCalden ◽  
Douglas DR Naudie ◽  
James L Howard
Keyword(s):  
Soft Tissue ◽  
Total Hip Arthroplasty ◽  
Hip Arthroplasty ◽  
Femoral Stem ◽  
Tissue Reaction ◽  
Harris Hip Score ◽  
Total Hip ◽  
Tissue Reactions ◽  
Clinical Records

Introduction: Birmingham Hip Resurfacing (BHR) implants may be combined with a conventional femoral stem to create a modular metal-on-metal total hip arthroplasty (BHR MoM THA). There is little outcome data regarding this construct. This study examines midterm outcomes of BHR MoM THA compared to oxidised zirconium total hip arthroplasty (THA). Methods: A retrospective institutional review identified all patients receiving BHR MoM THA between April 2005 and February 2011 and a matched control cohort of zirconium THA patients. Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Harris Hip Score (HHS), and SF-12 Health status scores were obtained. Revisions and complications were collected from clinical records. Radiographs were assessed for evidence of component malposition, loosening, osteolysis, or heterotopic ossification. Results: 63 modular BHR MoM THA were identified in 61 patients (36 with BHR cups, 27 with R3 cups) and 63 zirconium THA in 58 matched controls. Mean follow-up was 58 months. 14 BHR MoM THA hips (22.2%) were revised (4 infections, 1 dislocation, 9 soft tissue reactions) compared to 3 (4.8%) zirconium THA (all infections). At latest follow-up, 18.4% of surviving BHR MoM THA hips were painful compared to 0.5% of zirconium THA controls ( p < 0.001). WOMAC, HHS, and SF-12 did not differ significantly between surviving members of the 2 groups. Discussion: BHR MoM THA demonstrated a high revision rate, largely for adverse local soft tissue reaction and pain. Among those not revised, many reported some residual pain despite similar quality of life measures to those who received zirconium THA.

A Retrospective Cohort Study on the Influence of Comorbidity on Soft Tissue Reactions, Revision Surgery, and Implant Loss in Bone-anchored Hearing Implants

2015 ◽  
Vol 36 (5) ◽  
pp. 812-818 ◽  
Author(s):  
Christine A. den Besten ◽  
Rik C. Nelissen ◽  
Petronella G. M. Peer ◽  
Hubert T. Faber ◽  
Catherina A. J. Dun ◽  
...  
Keyword(s):  
Cohort Study ◽  
Soft Tissue ◽  
Revision Surgery ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Soft Tissue Reactions ◽  
Tissue Reactions

Soft tissue reactions evoked by implanted gallium phosphide

Biomaterials ◽  
2008 ◽  
Vol 29 (35) ◽  
pp. 4598-4604 ◽  
Author(s):  
Cecilia E. Linsmeier ◽  
Lars Wallman ◽  
Linda Faxius ◽  
Jens Schouenborg ◽  
Lars M. Bjursten ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Gallium Phosphide ◽  
Soft Tissue Reactions ◽  
Tissue Reactions

The New Baha Implant

2012 ◽  
Vol 146 (6) ◽  
pp. 979-983 ◽  
Author(s):  
Riccardo D’Eredità ◽  
Matteo Caroncini ◽  
Roberto Saetti
Keyword(s):  
Revision Surgery ◽  
Tertiary Care ◽  
Case Series ◽  
Titanium Implant ◽  
Skin Incision ◽  
Healing Time ◽  
Early Loading ◽  
Soft Tissue Reactions ◽  
Tissue Reactions ◽  
Age Range

Objectives. To assess stability of a new-design titanium implant (Cochlear Baha BAI300) in bone-anchored hearing aid (Baha) recipients over time. Study Design and Setting. Prospective case series with planned data collection at a tertiary care institution. Twelve patients who underwent Baha surgery over 12 months were analyzed. Subjects. All patients (3 children, age range 6-10 years, mean 7.7 years, median 7.3 years; 9 adults, age range 34-73 years, mean 52.8 years, median 48 years) underwent the 1-stage procedure following the standard Brånemark technique. In all procedures, the single-skin incision was applied. Methods. The stability of the implant was measured with implant stability quotient (ISQ) measurement tests. All patients were tested at surgery and every week after for 1 year. Wound-healing time, degree of soft tissue reactions around the abutment, and need for revision surgery were examined. Two-tailed Student t test and χ2 for all comparisons were calculated; P < .05 values were considered significant. Results. The new implant showed a steep increase of ISQ values over the first 2 weeks and reached stable ISQ values 3 weeks after surgery. Complete skin healing time was obtained in 8 days on average (range, 7-12 days; median 7.6 days). Neither implant extrusion nor skin revision surgery was observed in our patients during the first year of follow-up. Conclusions. This new implant revealed stability and fast integration. The data from the present study suggest the new implant may be suitable for early loading protocols.

Soft tissue reactions following cochlear implantation

2018 ◽  
Vol 276 (2) ◽  
pp. 343-347
Author(s):  
Mohnish Grover ◽  
Shitanshu Sharma ◽  
Tanmaya Kataria ◽  
Sunil Samdani ◽  
Shubham Agarwal ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Cochlear Implantation ◽  
Soft Tissue Reactions ◽  
Tissue Reactions
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