scholarly journals A Systematic Review of the Clinical Value and Applications of Three-Dimensional Printing in Renal Surgery

2019 ◽  
Vol 8 (7) ◽  
pp. 990 ◽  
Author(s):  
Catalina Lupulescu ◽  
Zhonghua Sun
Keyword(s):  
Systematic Review ◽  
3D Printing ◽  
Renal Disease ◽  
User Satisfaction ◽  
Surgical Simulation ◽  
Case Reports ◽  
Time Duration ◽  
Printing Process ◽  
Estimated Blood Loss ◽  
3D Printed

The purpose of this systematic review is to collate and analyse the current literature which examines clinical applications of 3D printing for renal disease, alongside cost and time duration factors associated with the printing process. A comprehensive search of the literature was performed across five different databases to identify studies that qualitatively and quantitatively assessed the value of 3D-printed kidney models for renal disease. Twenty-seven studies met the selection criteria for inclusion in the review. Twenty-five were original studies, and two were case reports. Of the 22 studies reporting a qualitative evaluation, the analysis of findings demonstrated the value of the 3D-printed models in areas of clinician and patient education, and pre-surgical simulation for complex cases of renal disease. Of five studies performing a quantitative analysis, the analysis of results displayed a high level of spatial and anatomical accuracy amongst models, with benefits including reducing estimated blood loss and risk of intra-operative complications. Fourteen studies evaluated manufacturing costs and time duration, with costs ranging from USD 1 to 1000 per model, and time duration ranging from 15 min to 9 days. This review shows that the use of customised 3D-printed models is valuable in the education of junior surgeons as well as the enhancement of operative skills for senior surgeons due to a superior visualisation of anatomical networks and pathologic morphology compared to volumetric imaging alone. Furthermore, 3D-printed kidney models may facilitate interdisciplinary communication and decision-making regarding the management of patients undergoing operative treatment for renal disease. It cannot be suggested that a more expensive material constitutes a higher level of user-satisfaction and model accuracy. However, higher costs in the manufacturing of the 3D-printed models reported, on average, a slightly shorter time duration for the 3D-printing process and total manufacturing time.

Effects of post-curing conditions on mechanical properties of 3D printed clear dental aligners

2020 ◽  
Vol 26 (8) ◽  
pp. 1337-1344 ◽  
Author(s):  
Prashant Jindal ◽  
Mamta Juneja ◽  
Divya Bajaj ◽  
Francesco Luke Siena ◽  
Philip Breedon
Keyword(s):  
Mechanical Properties ◽  
3D Printing ◽  
Mechanical Strength ◽  
Financial Burden ◽  
Experimental Studies ◽  
Cost Savings ◽  
Time Duration ◽  
Content Type ◽  
Curing Conditions ◽  
3D Printed

Purpose 3D printing techniques have been widely used for manufacturing complex parts for various dental applications. For achieving suitable mechanical strength, post-cure processing is necessary, where the relative time duration and temperature specification also needs to be defined. The purpose of this study/paper is to assess the effects of post curing conditions and mechanical properties of 3D printed clear dental aligners Design/methodology/approach Dental long-term clear resin material has been used for 3D printing of dental aligners using a Formlabs 3D printer for direct usage on patients. Post-curing conditions have been varied, all of which have been subjected to mechanical compression loading of 1,000 N to evaluate the curing effects on the mechanical strength of the aligners. Findings The experimental studies provide significant insight into both temperatures and time durations that could provide sufficient compressive mechanical strength to the 3D printed clear dental aligners. It was observed that uncured aligners deformed plastically with large deformations under the loading conditions, whereas aligners cured between 400°C–800°C for 15–20 min deformed elastically before fragmenting into pieces after safely sustaining higher compressive loads between 495 N and 666 N. The compressive modulus ratio for cured aligners ranged between 4.46 and 5.90 as compared to uncured aligners. For shorter cure time durations and lower temperature conditions, an appropriate elevated compressive strength was also achieved. Originality/value Based on initial assessments by dental surgeons, suitable customised clear aligners can be designed, printed and cured to the desired levels based on patient’s requirements. This could result in time, energy and unit production cost savings, which ultimately would help to alleviate the financial burden placed on both the health service and their patients.

scholarly journals Stress, strain and deformation of poly-lactic acid filament deposited onto polyethylene terephthalate woven fabric through 3D printing process

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Prisca Aude Eutionnat-Diffo ◽  
Yan Chen ◽  
Jinping Guan ◽  
Aurelie Cayla ◽  
Christine Campagne ◽  
...  
Keyword(s):  
Lactic Acid ◽  
3D Printing ◽  
Tensile Properties ◽  
Polyethylene Terephthalate ◽  
Polymeric Materials ◽  
Deposition Process ◽  
Woven Fabric ◽  
Poly Lactic Acid ◽  
Printing Process ◽  
3D Printed

Abstract Although direct deposition of polymeric materials onto textiles through 3D printing is a great technique used more and more to develop smart textiles, one of the main challenges is to demonstrate equal or better mechanical resistance, durability and comfort than those of the textile substrates before deposition process. This article focuses on studying the impact of the textile properties and printing platform temperature on the tensile and deformations of non-conductive and conductive poly lactic acid (PLA) filaments deposited onto polyethylene terephthalate (PET) textiles through 3D printing process and optimizing them using theoretical and statistical models. The results demonstrate that the deposition process affects the tensile properties of the printed textile in comparison with the ones of the textiles. The stress and strain at rupture of the first 3D printed PLA layer deposited onto PET textile material reveal to be a combination of those of the printed layer and the PET fabric due to the lower flexibility and diffusion of the polymeric printed track through the textile fabric leading to a weak adhesion at the polymer/textile interface. Besides, printing platform temperature and textile properties influence the tensile and deformation properties of the 3D printed PLA on PET textile significantly. Both, the washing process and the incorporation of conductive fillers into the PLA do not affect the tensile properties of the extruded polymeric materials. The elastic, total and permanent deformations of the 3D-printed PLA on PET fabrics are lower than the ones of the fabric before polymer deposition which demonstrates a better dimensional stability, higher stiffness and lower flexibility of these materials.

scholarly journals Utility of Three-Dimensional Printing for Preoperative Assessment of Children with Extra-Cranial Solid Tumors: A Systematic Review

2022 ◽  
Vol 14 (1) ◽  
pp. 32-39
Author(s):  
Sachit Anand ◽  
Nellai Krishnan ◽  
Prabudh Goel ◽  
Anjan Kumar Dhua ◽  
Vishesh Jain ◽  
...  
Keyword(s):  
Systematic Review ◽  
3D Printing ◽  
Solid Tumors ◽  
Surgical Planning ◽  
Three Dimensional ◽  
Current Evidence ◽  
Printing Technology ◽  
Three Dimensional Printing ◽  
3D Printed ◽  
Dimensional Printing

Background: In cases with solid tumors, preoperative radiological investigations provide valuable information on the anatomy of the tumor and the adjoining structures, thus helping in operative planning. However, due to a two-dimensional view in these investigations, a detailed spatial relationship is difficult to decipher. In contrast, three-dimensional (3D) printing technology provides a precise topographic view to perform safe surgical resections of these tumors. This systematic review aimed to summarize and analyze current evidence on the utility of 3D printing in pediatric extra-cranial solid tumors. Methods: The present study was registered on PROSPERO—international prospective register of systematic reviews (registration number: CRD42020206022). PubMed, Embase, SCOPUS, and Google Scholar databases were explored with appropriate search criteria to select the relevant studies. Data were extracted to study the bibliographic information of each article, the number of patients in each study, age of the patient(s), type of tumor, organ of involvement, application of 3D printing (surgical planning, training, and/or parental education). The details of 3D printing, such as type of imaging used, software details, printing technique, printing material, and cost were also synthesized. Results: Eight studies were finally included in the systematic review. Three-dimensional printing technology was used in thirty children with Wilms tumor (n = 13), neuroblastoma (n = 7), hepatic tumors (n = 8), retroperitoneal tumor (n = 1), and synovial sarcoma (n = 1). Among the included studies, the technology was utilized for preoperative surgical planning (five studies), improved understanding of the surgical anatomy of solid organs (two studies), and improving the parental understanding of the tumor and its management (one study). Computed tomography and magnetic resonance imaging were either performed alone or in combination for radiological evaluation in these children. Different types of printers and printing materials were used in the included studies. The cost of the 3D printed models and time involved (range 10 h to 4–5 days) were reported by two studies each. Conclusions: 3D printed models can be of great assistance to pediatric surgeons in understanding the spatial relationships of tumors with the adjacent anatomic structures. They also facilitate the understanding of families, improving doctor–patient communication.

scholarly journals Comparison between Tests and Simulations Regarding Bending Resistance of 3D Printed PLA Structures

Polymers ◽  
2021 ◽  
Vol 13 (24) ◽  
pp. 4371
Author(s):  
Dorin-Ioan Catana ◽  
Mihai-Alin Pop ◽  
Denisa-Iulia Brus
Keyword(s):  
Mechanical Properties ◽  
Additive Manufacturing ◽  
3D Printing ◽  
Process Parameters ◽  
Bending Stress ◽  
Test Results ◽  
Printing Process ◽  
Simulation Process ◽  
Bending Resistance ◽  
3D Printed

Additive manufacturing is one of the technologies that is beginning to be used in new fields of parts production, but it is also a technology that is constantly evolving, due to the advances made by researchers and printing equipment. The paper presents how, by using the simulation process, the geometry of the 3D printed structures from PLA and PLA-Glass was optimized at the bending stress. The optimization aimed to reduce the consumption of filament (material) simultaneously with an increase in the bending resistance. In addition, this paper demonstrates that the simulation process can only be applied with good results to 3D printed structures when their mechanical properties are known. The inconsistency of printing process parameters makes the 3D printed structures not homogeneous and, consequently, the occurrence of errors between the test results and those of simulations become natural and acceptable. The mechanical properties depend on the values of the printing process parameters and the printing equipment because, in the case of 3D printing, it is necessary for each combination of parameters to determine their mechanical properties through specific tests.

scholarly journals Clinical efficacy and effectiveness of 3D printing: a systematic review

BMJ Open ◽  
2017 ◽  
Vol 7 (12) ◽  
pp. e016891 ◽  
Author(s):  
Laura E Diment ◽  
Mark S Thompson ◽  
Jeroen H M Bergmann
Keyword(s):  
Systematic Review ◽  
3D Printing ◽  
Clinical Efficacy ◽  
Musculoskeletal System ◽  
Preoperative Planning ◽  
Maxillofacial Surgery ◽  
Oral And Maxillofacial Surgery ◽  
Level Of Evidence ◽  
Standard Clinical Practice ◽  
3D Printed

ObjectiveTo evaluate the clinical efficacy and effectiveness of using 3D printing to develop medical devices across all medical fields.DesignSystematic review compliant with Preferred Reporting Items for Systematic Reviews and Meta-Analyses.Data sourcesPubMed, Web of Science, OVID, IEEE Xplore and Google Scholar.MethodsA double-blinded review method was used to select all abstracts up to January 2017 that reported on clinical trials of a three-dimensional (3D)-printed medical device. The studies were ranked according to their level of evidence, divided into medical fields based on the International Classification of Diseases chapter divisions and categorised into whether they were used for preoperative planning, aiding surgery or therapy. The Downs and Black Quality Index critical appraisal tool was used to assess the quality of reporting, external validity, risk of bias, risk of confounding and power of each study.ResultsOf the 3084 abstracts screened, 350 studies met the inclusion criteria. Oral and maxillofacial surgery contained 58.3% of studies, and 23.7% covered the musculoskeletal system. Only 21 studies were randomised controlled trials (RCTs), and all fitted within these two fields. The majority of RCTs were 3D-printed anatomical models for preoperative planning and guides for aiding surgery. The main benefits of these devices were decreased surgical operation times and increased surgical accuracy.ConclusionsAll medical fields that assessed 3D-printed devices concluded that they were clinically effective. The fields that most rigorously assessed 3D-printed devices were oral and maxillofacial surgery and the musculoskeletal system, both of which concluded that the 3D-printed devices outperformed their conventional comparators. However, the efficacy and effectiveness of 3D-printed devices remain undetermined for the majority of medical fields. 3D-printed devices can play an important role in healthcare, but more rigorous and long-term assessments are needed to determine if 3D-printed devices are clinically relevant before they become part of standard clinical practice.

scholarly journals 3D printing in neurosurgery education: a review

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Grace M. Thiong’o ◽  
Mark Bernstein ◽  
James M. Drake
Keyword(s):  
3D Printing ◽  
Skull Base ◽  
Surgical Simulation ◽  
Simulation Modelling ◽  
Full Potential ◽  
Skull Defects ◽  
3D Printed ◽  
Dissection Techniques ◽  
Surgery Education ◽  
Neurosurgical Education

Abstract Objectives The objectives of this manuscript were to review the literature concerning 3D printing of brain and cranial vault pathology and use these data to define the gaps in global utilization of 3D printing technology for neurosurgical education. Methods Using specified criteria, literature searching was conducted to identify publications describing engineered neurosurgical simulators. Included in the study were manuscripts highlighting designs validated for neurosurgical skill transfer. Purely anatomical designs, lacking aspects of surgical simulation, were excluded. Eligible manuscripts were analyzed. Data on the types of simulators, representing the various modelled neurosurgical pathologies, were recorded. Authors’ countries of affiliation were also recorded. Results A total of thirty-six articles, representing ten countries in five continents were identified. Geographically, Africa as a continent was not represented in any of the publications. The simulation-modelling encompassed a variety of neurosurgical subspecialties including: vascular, skull base, ventriculoscopy / ventriculostomy, craniosynostosis, skull lesions / skull defects, intrinsic brain tumor and other. Finally, the vascular and skull base categories together accounted for over half (52.8 %) of the 3D printed simulated neurosurgical pathology. Conclusions Despite the growing body of literature supporting 3D printing in neurosurgical education, its full potential has not been maximized. Unexplored areas of 3D printing for neurosurgical simulation include models simulating the resection of intrinsic brain tumors or of epilepsy surgery lesions, as these require complex models to accurately simulate fine dissection techniques. 3D printed surgical phantoms offer an avenue for the advancement of global-surgery education initiatives.

scholarly journals Personalized Surgical Planning – The Use of 3D Printing in Oncological Pathology

2018 ◽  
Vol 1 (Supplement) ◽  
pp. 40
Author(s):  
E. Liciu ◽  
B. Frumuşeanu ◽  
B.M. Popescu ◽  
D.C. Florea ◽  
L. Niculescu ◽  
...  
Keyword(s):  
3D Printing ◽  
Neoadjuvant Chemotherapy ◽  
Surgical Planning ◽  
Preoperative Planning ◽  
Surgical Simulation ◽  
Malignant Tumors ◽  
Surgical Removal ◽  
Orthopedic Surgeons ◽  
3D Printed ◽  
Children And Young Adults

Abstract Introduction. Among the cases of malignant tumors, gathering 30% of them, the most frequent is the osteosarcoma. It occurs especially in children and young adults, the mean age being 14 years old. The treatment consists initially in neoadjuvant chemotherapy, followed by the surgical removal of the tumor. Due to aggressive malignant features (rapid increase in size, tendency to invade surrounding tissues, variable location), in multiple cases, the surgical treatment of osteosarcoma becomes a true challenge. Materials and methods. Nowadays, it is possible to create 3D printed models, by using CT and MRI, which are superior to the 3D graphical reconstructions. The 3D printing technique facilitates the production of these 1:1 scale printed models that faithfully embody the patient’s particular features concerning the anatomic pathology. The benefits gained from using such a modern tool allow the orthopedic surgeons to establish the measurements of a precise resection and to simulate the surgical maneuvers, as part of an elaborated modern surgical planning. Results. In this article, we presented the case of a 10-year-old patient diagnosed with femoral osteosarcoma and treated with neoadjuvant chemotherapy followed by GMRS surgical approach based on a preoperative planning involving a 3D printed model. This piece was used to provide precise information regarding the tumor, to allow preoperative measurements and a surgical simulation. Conclusion. The surgical accuracy can be increased by using a personalized preoperative planning based on a 3D printed model, leading to a lower rate of long/ short-term complications, recurrences, or metastases.

scholarly journals 3D Modeling and Printing in Congenital Heart Surgery: Entering the Stage of Maturation

2021 ◽  
Vol 9 ◽  
Author(s):  
Shi Joon Yoo ◽  
Nabil Hussein ◽  
Brandon Peel ◽  
John Coles ◽  
Glen S. van Arsdell ◽  
...  
Keyword(s):  
3D Printing ◽  
Surgical Training ◽  
Congenital Heart ◽  
Heart Surgery ◽  
Surgical Simulation ◽  
Heart Diseases ◽  
Congenital Heart Surgery ◽  
Congenital Heart Diseases ◽  
3D Printed ◽  
The Impact

3D printing allows the most realistic perception of the surgical anatomy of congenital heart diseases without the requirement of physical devices such as a computer screen or virtual headset. It is useful for surgical decision making and simulation, hands-on surgical training (HOST) and cardiovascular morphology teaching. 3D-printed models allow easy understanding of surgical morphology and preoperative surgical simulation. The most common indications for its clinical use include complex forms of double outlet right ventricle and transposition of the great arteries, anomalous systemic and pulmonary venous connections, and heterotaxy. Its utility in congenital heart surgery is indisputable, although it is hard to “scientifically” prove the impact of its use in surgery because of many confounding factors that contribute to the surgical outcome. 3D-printed models are valuable resources for morphology teaching. Educational models can be produced for almost all different variations of congenital heart diseases, and replicated in any number. HOST using 3D-printed models enables efficient education of surgeons in-training. Implementation of the HOST courses in congenital heart surgical training programs is not an option but an absolute necessity. In conclusion, 3D printing is entering the stage of maturation in its use for congenital heart surgery. It is now time for imagers and surgeons to find how to effectively utilize 3D printing and how to improve the quality of the products for improved patient outcomes and impact of education and training.

3D Printing and Growth Induced Bending based on PET-RAFT Polymerization

2020 ◽  
Author(s):  
Chris Bainbridge ◽  
Kyle Engel ◽  
Jianyong Jin
Keyword(s):  
3D Printing ◽  
Surface Properties ◽  
Raft Polymerization ◽  
Advanced Manufacturing ◽  
3D Printer ◽  
4D Printing ◽  
Printing Process ◽  
Raft Agent ◽  
3D Printed ◽  
First Time

4D printing has steadily become an emerging area of advanced manufacturing research and has produced some truly fantastic innovations. Previously we have demonstrated the 3D printing process based on PET-RAFT polymerization, and its subsequent capability in the post-production modification of surface properties. In this work, (1) we further optimized the PET-RAFT 3D printing formulation by replacing RAFT agent CDTPA with BTPA and adjusting the monomers composition; (2) we also observed the photodegradation of the photocatalysts EB and EY under 405nm light and the effects this has on 3D printing; (3) we then did successful 3D printing using a commercial 405nm DLP 3D printer, with an improved build speed of up to 2286 µm/hr; (4) lastly, for the first time we have demonstrated a method for growth induced bending of a 3D printed strip, where the growth on one side of the strip causes stress and the strip bends accordingly to reach a more comfortable position.

scholarly journals 3D printed complete removable dental prostheses: a narrative review

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Eva Anadioti ◽  
Leen Musharbash ◽  
Markus B. Blatz ◽  
George Papavasiliou ◽  
Phophi Kamposiora
Keyword(s):  
3D Printing ◽  
Clinical Performance ◽  
Case Reports ◽  
Complete Dentures ◽  
Exclusion Criteria ◽  
Digital Dentistry ◽  
Dental Prostheses ◽  
Removable Dental Prostheses ◽  
Cad Cam ◽  
3D Printed

Abstract Background The purpose of this paper is to review the available literature on three-dimensionally printed complete dentures in terms of novel biomaterials, fabrication techniques and workflow, clinical performance and patient satisfaction. Methods The methodology included applying a search strategy, defining inclusion and exclusion criteria, selecting studies and forming tables to summarize the results. Searches of PubMed, Scopus, and Embase databases were performed independently by two reviewers to gather literature published between 2010 and 2020. Results A total of 126 titles were obtained from the electronic database, and the application of exclusion criteria resulted in the identification of 21 articles pertaining to printed technology for complete dentures. Current innovations and developments in digital dentistry have successfully led to the fabrication of removable dental prostheses using CAD/CAM technologies. Milled dentures have been studied more than 3D printed ones in the currently available literature. The limited number of clinical studies, mainly case reports, suggest current indications of 3D printing in denture fabrication process to be custom tray, record bases, trial, interim or immediate dentures but not definitive prostheses fabrication. Limitations include poor esthetics and retention, inability to balance occlusion and low printer resolution. Conclusions Initial studies on digital dentures have shown promising short-term clinical performance, positive patient-related results and reasonable cost-effectiveness. 3D printing has potential to modernize and streamline the denture fabrication techniques, materials and workflows. However, more research is required on the existing and developing materials and printers to allow for advancement and increase its application in removable prosthodontics.

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