scholarly journals Real-World Use and Outcomes of ALK-Positive Crizotinib-Treated Metastatic NSCLC in US Community Oncology Practices: A Retrospective Observational Study

2018 ◽  
Vol 7 (6) ◽  
pp. 129 ◽  
Author(s):  
Craig Reynolds ◽  
Elizabeth Masters ◽  
Jenny Black-Shinn ◽  
Marley Boyd ◽  
Jack Mardekian ◽  
...  
Keyword(s):  
Observational Study ◽  
Real World ◽  
Retrospective Observational Study ◽  
Metastatic Nsclc ◽  
Community Oncology ◽  
Alk Positive

scholarly journals P3.02a-019 Real World Utilization and Outcomes of ALK-Positive Crizotinib Treated Metastatic NSCLC Patients in US Community Oncology Practice

2017 ◽  
Vol 12 (1) ◽  
pp. S1172-S1173 ◽  
Author(s):  
Craig Reynolds ◽  
Elizabeth Masters ◽  
Jenny Black-Shinn ◽  
Jack Mardekian ◽  
Janet Espirito ◽  
...  
Keyword(s):  
Real World ◽  
Metastatic Nsclc ◽  
Community Oncology ◽  
Alk Positive ◽  
Oncology Practice ◽  
Nsclc Patients

Understanding the Users with Chronic Pain on AI CBT Mental Health App (Wysa): A Mixed-Methods Retrospective Observational Study (Preprint)

2021 ◽  
Author(s):  
S Meheli ◽  
Chaitali Sinha ◽  
Madhura Kabada
Keyword(s):  
Mental Health ◽  
Chronic Pain ◽  
Pain Management ◽  
Observational Study ◽  
Real World ◽  
Effect Size ◽  
Retrospective Observational Study ◽  
Medium Effect ◽  
Health Concerns ◽  
Perceived Needs

BACKGROUND Digital health interventions can bridge barriers in access to treatment of care for individuals with chronic pain. OBJECTIVE This study aimed to evaluate the perceived needs, engagement and the effectiveness of the mental health app Wysa on mental health outcomes among real-world users who reported chronic pain and engaged with the app for support. METHODS Real-world data from users (N = 2,194) who reported chronic pain and associated health conditions in their conversations with a mental health app was analyzed using a mixed-method retrospective observational study. An inductive thematic analysis was used to analyse conversational data of users with chronic pain to assess perceived needs, along with comparative macro-analyses of conversational flows to capture engagement within the app. Additionally, the scores from a subset of users who completed a set of pre-post assessment questionnaires, namely PHQ-9 (N=69) and GAD-7 (N=57), were examined to evaluate the effectiveness of Wysa in providing support for mental health concerns for those managing chronic pain. RESULTS The themes emerging from the conversations of users with chronic pain included Health Concerns, Socioeconomic Concerns, and Pain Management Concerns. Findings from the quantitative analysis indicated that users with chronic pain showed significantly greater app engagement (p value <2.2e-16) than users without chronic pain, with a large effect size (Vargha and Delaney’s A- 0.76 -0.8). Furthermore, the sample of users with pre-post assessments during the study period were found to have significant improvements in group means on both PHQ-9 and GAD-7 symptom scores, with medium effect size (Cohens’d, 0.6-0.61), respectively. CONCLUSIONS The findings indicate that users look for tools that can help them address their concerns related to mental health, pain management, and sleep issues. The study findings also indicate the breadth of needs for users with chronic pain and the lack of support structures, and suggests that Wysa can provide effective support to bridge the gap.

scholarly journals Real-world use of procalcitonin and other biomarkers among sepsis hospitalizations in the United States: A retrospective, observational study

PLoS ONE ◽  
2018 ◽  
Vol 13 (10) ◽  
pp. e0205924 ◽  
Author(s):  
Eric Gluck ◽  
H. Bryant Nguyen ◽  
Kishore Yalamanchili ◽  
Margaret McCusker ◽  
Jaya Madala ◽  
...  
Keyword(s):  
United States ◽  
Observational Study ◽  
Real World ◽  
The United States ◽  
Retrospective Observational Study
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