scholarly journals Optimal Pharmacologic Treatment Strategies in Obesity and Type 2 Diabetes

2014 ◽  
Vol 3 (2) ◽  
pp. 595-613 ◽  
Author(s):  
Gayotri Goswami ◽  
Nataliya Shinkazh ◽  
Nichola Davis
2013 ◽  
Vol 22 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Tatsuhiko Urakami ◽  
Remi Kuwabara ◽  
Masako Habu ◽  
Ayako Yoshida ◽  
Misako Okuno ◽  
...  

2021 ◽  
Vol 11 (20) ◽  
pp. 9436
Author(s):  
Abegail Tshivhase ◽  
Tandi Matsha ◽  
Shanel Raghubeer

Maturity-Onset Diabetes of the Young (MODY) is the most common form of monogenic diabetes resulting from a single gene mutation. It is characterized by mild hyperglycemia, autosomal dominant inheritance, early onset of diabetes (<25 years), insulin resistance, and preservation of endogenous insulin secretion. Currently, 14 MODY subtypes have been identified, with differences in incidence, clinical features, diabetes severity and related complications, and treatment response. This type of diabetes is mostly misdiagnosed as either type 1 or type 2 diabetes mellitus because it is difficult to differentiate between these forms of diabetes due to clinical similarities, the high cost of genetic testing, and lack of awareness. As a result, thousands of patients are not receiving appropriate treatment. Accurate diagnosis would allow for more effective therapeutic management and treatment strategies that are distinct from those used for type 1 and type 2 diabetes. This review serves to explore MODY subtypes, diagnosis, and treatment, and increase awareness of MODY incidence.


2021 ◽  
Author(s):  
Mohammadhosain Afrand ◽  
Mohammad Afkhami-Ardekani ◽  
Ahmad Shojaoddiny-Ardekani ◽  
Azita Ariaeinejad

Metabolic syndrome is defined as the co-occurrence of metabolic risk factors for both type 2 diabetes and cardiovascular disease (i.e. abdominal obesity, hyperglycemia, dyslipidemia, and hypertension). Indeed, metabolic syndrome is an important risk factor for subsequent development of type 2 diabetes and/or CVD. Thus, the key clinical implication of a diagnosis of metabolic syndrome is the identification of a patient who needs aggressive lifestyle modification focused on weight reduction and increased physical activity. Multiple different phenotypes and ethnic-specific values for waist circumference are included within metabolic syndrome, with indications for differing treatment strategies. This book covers several aspects of metabolic syndrome, including its definition, diagnostic criteria, preventive measures, and treatment, as well as the possible association between ethnicity and the occurrence of metabolic syndrome.


Sign in / Sign up

Export Citation Format

Share Document