scholarly journals Hyperferritinemia—A Clinical Overview

2021 ◽  
Vol 10 (9) ◽  
pp. 2008
Author(s):  
Miriam Sandnes ◽  
Rune J. Ulvik ◽  
Marta Vorland ◽  
Håkon Reikvam

Ferritin is one of the most frequently requested laboratory tests in primary and secondary care, and levels often deviate from reference ranges. Serving as an indirect marker for total body iron stores, low ferritin is highly specific for iron deficiency. Hyperferritinemia is, however, a non-specific finding, which is frequently overlooked in general practice. In routine medical practice, only 10% of cases are related to an iron overload, whilst the rest is seen as a result of acute phase reactions and reactive increases in ferritin due to underlying conditions. Differentiation of the presence or absence of an associated iron overload upon hyperferritinemia is essential, although often proves to be complex. In this review, we have performed a review of a selection of the literature based on the authors’ own experiences and assessments in accordance with international recommendations and guidelines. We address the biology, etiology, and epidemiology of hyperferritinemia. Finally, an algorithm for the diagnostic workup and management of hyperferritinemia is proposed, and general principles regarding the treatment of iron overload are discussed.

2020 ◽  
Vol 3 (1) ◽  
pp. 87-89
Author(s):  
David IMB

Some years ago – let’s say, for sure, some decades ago – a “good physician” was considered the one who would request a few laboratory tests to some patient and they would come out all altered. – Yes – one would say – he got it right to the point, disease concerning. However, in the 21st century, when we have moved the focus of preventive care from prevention of diseases to health maintenance, we believe that the “good physician” may be considered the one that aims at keeping all the test results basically normal. Actually, more than that: optimal. In fact, keeping the eyes on optimal test results is a major goal for Age Management practitioners. For that, even if we still have the established reference ranges, we’ve got to have our own interpretation of the tests we are used to from a different, more detailed standpoint than in the general practice. Some normal results must be seen as subnormal, which are, indeed, still different from abnormal. Some results may also be considered critical – that is, those ones which demand some urgent and immediate action.


2020 ◽  
pp. 120-127
Author(s):  
E. N. Skvortsova ◽  
O. P. Deryugina

The article discusses the results of a study on the selection of wax inhibitors that can be used at the Kondinskoye oil field during transportation and dehydration of the emulsion.Asphaltene precipitation is one of the most serious issues in oil production. The experiment was conducted in order to select the most effective wax inhibitors. We have carried out laboratory tests to choose the most effective wax inhibitor in the conditions of oil production, collection, preparation and external transport systems at the Kondinskoye oil field. Based on the data obtained, wax inhibitor-2, wax inhibitor-4, and wax inhibitor-6 have shown the best results in ensuring the efficiency of inhibition, which should be at least 70 %, and, therefore, they can be allowed to pilot tests. The recommended initial dosage of inhibitors according to the results obtained during pilot tests should be at least 500 g/t of oil.


Sensors ◽  
2020 ◽  
Vol 21 (1) ◽  
pp. 166
Author(s):  
Jakub T. Wilk ◽  
Beata Bąk ◽  
Piotr Artiemjew ◽  
Jerzy Wilde ◽  
Maciej Siuda

Honeybee workers have a specific smell depending on the age of workers and the biological status of the colony. Laboratory tests were carried out at the Department of Apiculture at UWM Olsztyn, using gas sensors installed in two twin prototype multi-sensor detectors. The study aimed to compare the responses of sensors to the odor of old worker bees (3–6 weeks old), young ones (0–1 days old), and those from long-term queenless colonies. From the experimental colonies, 10 samples of 100 workers were taken for each group and placed successively in the research chambers for the duration of the study. Old workers came from outer nest combs, young workers from hatching out brood in an incubator, and laying worker bees from long-term queenless colonies from brood combs (with laying worker bee’s eggs, humped brood, and drones). Each probe was measured for 10 min, and then immediately for another 10 min ambient air was given to regenerate sensors. The results were analyzed using 10 different classifiers. Research has shown that the devices can distinguish between the biological status of bees. The effectiveness of distinguishing between classes, determined by the parameters of accuracy balanced and true positive rate, of 0.763 and 0.742 in the case of the best euclidean.1nn classifier, may be satisfactory in the context of practical beekeeping. Depending on the environment accompanying the tested objects (a type of insert in the test chamber), the introduction of other classifiers as well as baseline correction methods may be considered, while the selection of the appropriate classifier for the task may be of great importance for the effectiveness of the classification.


2003 ◽  
Vol 11 (3) ◽  
pp. 162-167 ◽  
Author(s):  
Linda Wang ◽  
Paulo Henrique Perlatti D'Alpino ◽  
Lawrence Gonzaga Lopes ◽  
José Carlos Pereira

A wide variety of dental products that are launched on the market becomes the correct selection of these materials a difficult task. Although the mechanical properties do not necessarily represent their actual clinical performance, they are used to guide the effects of changes in their composition or processing on these properties. Also, these tests might help somehow the clinician to choose once comparisons between former formulations and new ones, as well as, with the leading brand, are highlighted by manufactures. This paper presents a review of the most important laboratory tests. In this manner, the knowledge of these tests will provide a critical opinion related to the properties of different dental materials.


2020 ◽  
Vol 1 (2) ◽  
pp. 65-70
Author(s):  
Esa Indah Ayudia ◽  
Huntari Harahap ◽  
Irfannuddin Irfannuddin

  Obesity is a condition in which the ratio of body weight and height exceeds the specified standards. Obesity is an increase in total body fat, that is, if you are found to be overweight> 20% in men and 25% in women because of fat. The intermittent fasting diet is a calorie restriction method that is widely used for health or weight loss reasons. Overall kidney function is based on nephron function and impaired function is caused by decreased nephron action. Several laboratory tests have been developed to evaluate kidney function and identify the disorder early on. This can help clinicians to take early prevention and management in order to prevent the progression of kidney disorders to kidney failure. Renal function tests are carried out by examining the levels of urea and cretinin.    


2015 ◽  
Vol 65 (632) ◽  
pp. e204-e206 ◽  
Author(s):  
Jessica Webb ◽  
Chris Arden ◽  
John B Chambers

BMJ ◽  
2004 ◽  
Vol 328 (7442) ◽  
pp. s122.3-s122
Author(s):  
Susan Kersley

Got a career or related problem that needs answering? Can't find the right person to point you in the right direction? Log on to the Advice Zone (www.bmjcareers.com/advicezone) for reliable medical careers advice. You can post a question or see if one of our 300 advisers has already answered a similar question. Here is a selection of questions and answers posted on the site.


Sign in / Sign up

Export Citation Format

Share Document