scholarly journals Cartilage Micrografts as a Novel Non-Invasive and Non-Arthroscopic Autograft Procedure for Knee Chondropathy: Three-Year Follow-Up Study

2021 ◽  
Vol 10 (2) ◽  
pp. 322
Author(s):  
Marco Marcarelli ◽  
Marcello Zappia ◽  
Lorenzo Rissolio ◽  
Chiara Baroni ◽  
Carlo Astarita ◽  
...  
Keyword(s):  
Oxford Knee Score ◽  
Resonance Imaging ◽  
Non Invasive ◽  
Follow Up Study ◽  
Chondral Defects ◽  
Before And After ◽  
Magnetic Resonance Imaging Mri

(1) Background: Focal chondral defects of the knee can significantly impair patient quality of life. Although different options are available, they are still not conclusive and have several limitations. The aim of this study was to evaluate the role of autologous cartilage micrografts in the treatment of knee chondropathy. (2) Methods: Eight patients affected by knee chondropathy were evaluated before and after 6 months and 3 years following autologous cartilage micrografts by magnetic resonance imaging (MRI) for cartilage measurement and clinical assessment. (3) Results: All patients recovered daily activities, reporting pain reduction without the need for analgesic therapy; Oxford Knee Score (OKS) was 28.4 ± 6 and 40.8 ± 6.2 and visual analogue scale (VAS) was 5.5 ± 1.6 and 1.8 ± 0.7 before and after 6 months following treatment, respectively. Both scores remained stable after 3 years. Lastly, a significant improvement of the cartilage thickness was observed using MRI after 3 years. (4) Conclusions: Autologous cartilage micrografts can promote the formation of new cartilage, and could be a valid approach for the treatment of knee chondropathy.

scholarly journals Diffusion-Weighted Imaging in Oncology: An Update

Cancers ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1493 ◽  
Author(s):  
Carmelo Messina ◽  
Rodolfo Bignone ◽  
Alberto Bruno ◽  
Antonio Bruno ◽  
Federico Bruno ◽  
...  
Keyword(s):  
Diffusion Weighted Imaging ◽  
Water Molecules ◽  
Non Invasive ◽  
Diffusion Weighted ◽  
Routine Magnetic Resonance Imaging ◽  
Treatment Responses ◽  
Magnetic Resonance Imaging Mri ◽  
Almost All

To date, diffusion weighted imaging (DWI) is included in routine magnetic resonance imaging (MRI) protocols for several cancers. The real additive role of DWI lies in the “functional” information obtained by probing the free diffusivity of water molecules into intra and inter-cellular spaces that in tumors mainly depend on cellularity. Although DWI has not gained much space in some oncologic scenarios, this non-invasive tool is routinely used in clinical practice and still remains a hot research topic: it has been tested in almost all cancers to differentiate malignant from benign lesions, to distinguish different malignant histotypes or tumor grades, to predict and/or assess treatment responses, and to identify residual or recurrent tumors in follow-up examinations. In this review, we provide an up-to-date overview on the application of DWI in oncology.

scholarly journals Impact of recent life events on the health related quality of life of adolescents and youths: the role of gender and life events typologies in a follow-up study

2010 ◽  
Vol 8 (1) ◽  
pp. 71 ◽  
Author(s):  
Ester Villalonga-Olives ◽  
Sonia Rojas-Farreras ◽  
Gemma Vilagut ◽  
Jorge A Palacio-Vieira ◽  
José Valderas ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Life Events ◽  
Health Related Quality ◽  
Follow Up Study ◽  
Related Quality ◽  
Health Related

The role of magnetic resonance imaging in the evaluation of the functionally single ventricle before and after conversion to the Fontan circulation

2005 ◽  
Vol 15 (S3) ◽  
pp. 51-56 ◽  
Author(s):  
Pierluigi Festa ◽  
Lamia Ait Ali ◽  
Massimo Bernabei ◽  
Daniele De Marchi
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Fontan Circulation ◽  
Resonance Imaging ◽  
Full Spectrum ◽  
Non Invasive ◽  
Current Review ◽  
Future Clinical Practice ◽  
Before And After

Magnetic resonance imaging is a powerful diagnostic tool, able to give us accurate anatomical and functional insights concerning the structure of the heart, and capable of overcoming some of the drawbacks and limitations of echocardiography and catheterization. The aim of our current review is to highlight the advantages and applications of the technique in the evaluation of patients with functionally univentricular hearts before and after conversion to the Fontan circulation. Most of these patients will have undergone surgery several times in their life, with a certain body size, and with less than optimal echocardiographic windows because of the surgical scars. Moreover, vascular access is sometimes unavailable due to previous catheterizations. Furthermore, resonance imaging is non-invasive, and can be performed without sedation in patients older than 8 years. Since many of the current techniques, some of them still experimental, will be used extensively in future clinical practice, physicians should be aware of the full spectrum of capabilities of resonance imaging. We will highlight all these applications in the sections which follow.

ICHD-II Diagnostic Criteria for Tolosa—Hunt Syndrome in Idiopathic Inflammatory Syndromes of the Orbit and/or the Cavernous Sinus

Cephalalgia ◽  
2008 ◽  
Vol 28 (6) ◽  
pp. 577-584 ◽  
Author(s):  
S Colnaghi ◽  
M Versino ◽  
E Marchioni ◽  
A Pichiecchio ◽  
S Bastianello ◽  
...  
Keyword(s):  
Diagnostic Criteria ◽  
Response To Treatment ◽  
High Dose ◽  
Inclusion Criteria ◽  
Resonance Imaging ◽  
Hunt Syndrome ◽  
Magnetic Resonance Imaging Mri

A bibliographical search was conducted for papers published between 1999 and 2007 to verify the validity of International Classification of Headache Disorders (ICHD)-II criteria for the Tolosa-Hunt syndrome (THS) in terms of (i) the role of magnetic resonance imaging (MRI); (ii) which steroid treatment should be considered as adequate; and (iii) the response to treatment. Of 536 articles, 48, reporting on 62 patients, met the inclusion criteria. MRI was positive in 92.1% of the cases and it normalized after clinical resolution. There was no evidence of which steroid schedule should be considered as adequate; high-dose steroids are likely to be more effective both to induce resolution and to avoid recurrences. Pain subsided within the time limit required by the ICHD-II criteria, but signs did not. We conclude that THS diagnostic criteria can be improved on the basis of currently available data. MRI should play a pivotal role both to diagnose and to follow-up THS.

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