scholarly journals Light Sources in Europe—Case Study: The COMPACTLIGHT Collaboration

Instruments ◽  
2019 ◽  
Vol 3 (3) ◽  
pp. 43 ◽  
Author(s):  
Nikolaos Gazis ◽  
Eugene Tanke ◽  
Theodoros Apostolopoulos ◽  
Katerina Pramatari ◽  
Regina Alexandra Rochow-Carbone ◽  
...  
Keyword(s):  
Generation X ◽  
Free Electron Laser ◽  
European Region ◽  
Light Sources ◽  
Market Survey ◽  
X Ray ◽  
Funded Project ◽  
The Many ◽  
Conceptual Design Report

The light sources currently existing or under development in Europe address needs in the Central and Northwestern regions, whereas in the Southeastern European region there is no facility of this kind. The CompactLight collaboration, an H2020 funded project, is going to deliver a Conceptual Design Report (CDR) of a novel generation X-ray Free Electron Laser (XFEL) facility which is compact, innovative, relatively cheap and to be implemented for industrial and medical applications. The CDR will facilitate technological updates of the many European region institutions and enable them to construct a novel light source. Cost and risk analysis, as well as technology transfer and market survey of the project results are also discussed.

scholarly journals Successful sample preparation for serial crystallography experiments

2019 ◽  
Vol 52 (6) ◽  
pp. 1385-1396 ◽  
Author(s):  
John H. Beale ◽  
Rachel Bolton ◽  
Stephen A. Marshall ◽  
Emma V. Beale ◽  
Stephen B. Carr ◽  
...  
Keyword(s):  
Sample Preparation ◽  
Case Studies ◽  
Free Electron Laser ◽  
Laser Light ◽  
Light Sources ◽  
Batch Crystallization ◽  
X Ray ◽  
Vapour Diffusion ◽  
Serial Crystallography ◽  
The Many

Serial crystallography, at both synchrotron and X-ray free-electron laser light sources, is becoming increasingly popular. However, the tools in the majority of crystallization laboratories are focused on producing large single crystals by vapour diffusion that fit the cryo-cooled paradigm of modern synchrotron crystallography. This paper presents several case studies and some ideas and strategies on how to perform the conversion from a single crystal grown by vapour diffusion to the many thousands of micro-crystals required for modern serial crystallography grown by batch crystallization. These case studies aim to show (i) how vapour diffusion conditions can be converted into batch by optimizing the length of time crystals take to appear; (ii) how an understanding of the crystallization phase diagram can act as a guide when designing batch crystallization protocols; and (iii) an accessible methodology when attempting to scale batch conditions to larger volumes. These methods are needed to minimize the sample preparation gap between standard rotation crystallography and dedicated serial laboratories, ultimately making serial crystallography more accessible to all crystallographers.

scholarly journals The Dynamic Response of Polymers Interrogated by 3rd Generation X-ray Light Sources

2019 ◽  
Author(s):  
Andrew Abbott ◽  
Brittany Branch ◽  
Eric N. Brown ◽  
Carl A. Carlson ◽  
Bradford E. Clements ◽  
...  
Keyword(s):  
Dynamic Response ◽  
Generation X ◽  
Light Sources ◽  
X Ray

Time-Resolved X-Ray Scattering from Coherent Excitations in Solids

MRS Bulletin ◽  
2010 ◽  
Vol 35 (7) ◽  
pp. 514-519 ◽  
Author(s):  
Mariano Trigo ◽  
David Reis
Keyword(s):  
Time Domain ◽  
Free Electron Laser ◽  
Femtosecond Lasers ◽  
Light Sources ◽  
Time Resolved ◽  
X Ray ◽  
X Ray Scattering ◽  
Far From Equilibrium ◽  
The Time Domain ◽  
Ray Scattering

AbstractRecent advances in pulsed x-ray sources have opened up new opportunities to study the dynamics of matter directly in the time domain with picosecond to femtosecond resolution. In this article, we present recent results from a variety of ultrafast sources on time-resolved x-ray scattering from elementary excitations in periodic solids. A few representative examples are given on folded acoustic phonons, coherent optical phonons, squeezed phonons, and polaritons excited by femtosecond lasers. Next-generation light sources, such as the x-ray-free electron laser, will lead to improvements in coherence, flux, and pulse duration. These experiments demonstrate potential opportunities for studying matter far from equilibrium on the fastest time scales and shortest distances that will be available in the coming years.

Few-femtosecond timing at fourth-generation X-ray light sources

2011 ◽  
Vol 5 (3) ◽  
pp. 162-165 ◽  
Author(s):  
F. Tavella ◽  
N. Stojanovic ◽  
G. Geloni ◽  
M. Gensch
Keyword(s):  
Generation X ◽  
Fourth Generation ◽  
Light Sources ◽  
X Ray

scholarly journals Transverse gradient in Apple-type undulators

2017 ◽  
Vol 24 (3) ◽  
pp. 600-608 ◽  
Author(s):  
M. Calvi ◽  
C. Camenzuli ◽  
E. Prat ◽  
Th. Schmidt
Keyword(s):  
Free Electron ◽  
Free Electron Laser ◽  
Polarized Light ◽  
Light Sources ◽  
X Ray ◽  
Flexible Devices ◽  
Delta Type ◽  
Transverse Gradient ◽  
New Generation ◽  
Operational Modes

Apple-type undulators are globally recognized as the most flexible devices for the production of variable polarized light in the soft X-ray regime, both at synchrotron and free-electron laser facilities. Recently, the implementation of transverse gradient undulators has been proposed to enhance the performance of new generation light sources. In this paper it is demonstrated that Apple undulators do not only generate linear and elliptical polarized light but also variable transverse gradient under certain conditions. A general theoretical framework is introduced to evaluate the K-value and its transverse gradient for an Apple undulator, and formulas for all regular operational modes and different Apple types (including the most recent Delta type and Apple X) are calculated and critically discussed.

scholarly journals Effects of x-ray free-electron laser pulse intensity on the Mn Kβ1,3 x-ray emission spectrum in photosystem II—A case study for metalloprotein crystals and solutions

2021 ◽  
Vol 8 (6) ◽  
pp. 064302
Author(s):  
Thomas Fransson ◽  
Roberto Alonso-Mori ◽  
Ruchira Chatterjee ◽  
Mun Hon Cheah ◽  
Mohamed Ibrahim ◽  
...  
Keyword(s):  
Photosystem Ii ◽  
Laser Pulse ◽  
Emission Spectrum ◽  
Free Electron ◽  
Free Electron Laser ◽  
X Ray ◽  
Pulse Intensity ◽  
Laser Pulse Intensity

scholarly journals On the release ofcppxfelfor processing X-ray free-electron laser images

2016 ◽  
Vol 49 (3) ◽  
pp. 1065-1072 ◽  
Author(s):  
Helen Mary Ginn ◽  
Gwyndaf Evans ◽  
Nicholas K. Sauter ◽  
David Ian Stuart
Keyword(s):  
Data Analysis ◽  
Free Electron ◽  
Free Electron Laser ◽  
Software Package ◽  
Light Sources ◽  
Data Sets ◽  
Delivery Methods ◽  
Data Set ◽  
X Ray ◽  
Software Packages

As serial femtosecond crystallography expands towards a variety of delivery methods, including chip-based methods, and smaller collected data sets, the requirement to optimize the data analysis to produce maximum structure quality is becoming increasingly pressing. Herecppxfel, a software package primarily written in C++, which showcases several data analysis techniques, is released. This software package presently indexes images using DIALS (diffraction integration for advanced light sources) and performs an initial orientation matrix refinement, followed by post-refinement of individual images against a reference data set.Cppxfelis released with the hope that the unique and useful elements of this package can be repurposed for existing software packages. However, as released, it produces high-quality crystal structures and is therefore likely to be also useful to experienced users of X-ray free-electron laser (XFEL) software who wish to maximize the information extracted from a limited number of XFEL images.

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