scholarly journals The Bioavailability, Extraction, Biosynthesis and Distribution of Natural Dihydrochalcone: Phloridzin

2021 ◽  
Vol 22 (2) ◽  
pp. 962
Author(s):  
Lei Tian ◽  
Jianxin Cao ◽  
Tianrui Zhao ◽  
Yaping Liu ◽  
Afsar Khan ◽  
...  
Keyword(s):  
Extraction Method ◽  
High Speed ◽  
High Performance ◽  
Natural Compound ◽  
Antibacterial Activities ◽  
Countercurrent Chromatography ◽  
Pharmacological Effects ◽  
Adsorption Technology ◽  
Phenolic Substances ◽  
Resin Adsorption

Phloridzin is an important phytochemical which was first isolated from the bark of apple trees. It is a member of the dihydrochalcones and mainly distributed in the plants of the Malus genus, therefore, the extraction method of phloridzin was similar to those of other phenolic substances. High-speed countercurrent chromatography (HSCCC), resin adsorption technology and preparative high-performance liquid chromatography (HPLC) were used to separate and purify phloridzin. Many studies showed that phloridzin had multiple pharmacological effects, such as antidiabetic, anti-inflammatory, antihyperglycaemic, anticancer and antibacterial activities. Besides, the physiological activities of phloridzin are cardioprotective, neuroprotective, hepatoprotective, immunomodulatory, antiobesity, antioxidant and so on. The present review summarizes the biosynthesis, distribution, extraction and bioavailability of the natural compound phloridzin and discusses its applications in food and medicine.

The Research Progress of Melanin

2011 ◽  
Vol 204-210 ◽  
pp. 2057-2060
Author(s):  
Jian Ming Wang ◽  
Ai Hua Ao ◽  
Chang Sheng Qiao ◽  
Yu Zhong ◽  
Yuan Yuan Zhang
Keyword(s):  
High Speed ◽  
High Performance ◽  
Analytical Techniques ◽  
Research Progress ◽  
Countercurrent Chromatography ◽  
New Techniques ◽  
Wide Range ◽  
High Performance Capillary Electrophoresis ◽  
Relationship Of ◽  
The Relationship

The sources of melanin and the sorts of melanin are introduced. New techniques for extraction and analysis of natural melanin were introduced. New analytical techniques are high performance liquid chromatography, high-speed countercurrent chromatography, high performance capillary electrophoresis and chromatography-mass spectrometry. The relationship of polyketide melanogenesis molecular biology to that of nonmelanin-producing pathways in a wide range of fungi and other organisms is discussed. The applications of melanin are introduced.

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